Lista de obras - Nicholas J Clemons - Dominio Público Uruguay

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death

artículo científico publicado en 2020

APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

artículo científico publicado en 2015

Advances in understanding the pathogenesis of Barrett's esophagus

artículo científico publicado en 2014

Barrett's esophagus: cancer and molecular biology.

artículo científico

Bridging the molecular divide: Alcohol-induced downregulation of PAX9 and tumour development.

artículo científico publicado en 2018

Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

artículo científico publicado en 2015

Characterization of a novel tumorigenic esophageal adenocarcinoma cell line: OANC1.

artículo científico publicado en 2014

Correction: Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

scientific article published on 18 March 2020

Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage ⬇️

artículo científico publicado en 2022

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

artículo científico publicado en 2022

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

artículo científico publicado en 2019

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

scientific article published on 01 August 2020

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.

artículo científico publicado en 2014

Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.

artículo científico publicado en 2005

Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.

artículo científico publicado en 2004

Inhibiting system xC- and glutathione biosynthesis - a potential Achilles' heel in mutant-p53 cancers.

artículo científico publicado en 2017

Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

artículo científico publicado en 2017

Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts

artículo científico publicado en 2015

Molecular changes in the phosphatidylinositide 3-kinase (PI3K) pathway are common in gastric cancer.

artículo científico publicado en 2013

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

artículo científico publicado en 2021

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

artículo científico publicado en 2010

Nitric oxide-mediated invasion in Barrett's high-grade dysplasia and adenocarcinoma.

artículo científico publicado en 2010

Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis

artículo científico publicado en 2016

Preclinical models for the study of Barrett's carcinogenesis

artículo científico publicado en 2018

Preclinical models of esophageal adenocarcinoma for drug development

artículo científico publicado en 2016

Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junction

artículo científico publicado en 2013

Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus.

artículo científico publicado en 2012

Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers

artículo científico publicado en 2010

TGF-beta signaling and its targeted therapy in gastrointestinal cancers

artículo científico publicado en 2018

TRAIL-induced apoptosis is enhanced by heat shock protein 70 expression

artículo científico publicado en 2006

The prognostic value of TP53 mutations in oesophageal adenocarcinoma: a systematic review and meta-analysis

artículo científico publicado en 2016

Translational research on Barrett's esophagus.

artículo científico publicado en 2014

Lista de obras de Nicholas J Clemons

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death

APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

Advances in understanding the pathogenesis of Barrett's esophagus

Barrett's esophagus: cancer and molecular biology.

Bridging the molecular divide: Alcohol-induced downregulation of PAX9 and tumour development.

Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

Characterization of a novel tumorigenic esophageal adenocarcinoma cell line: OANC1.

Correction: Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage ⬇️

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.

Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.

Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.

Inhibiting system xC- and glutathione biosynthesis - a potential Achilles' heel in mutant-p53 cancers.

Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation

Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts

Molecular changes in the phosphatidylinositide 3-kinase (PI3K) pathway are common in gastric cancer.

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

Nitric oxide-mediated invasion in Barrett's high-grade dysplasia and adenocarcinoma.

Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis

Preclinical models for the study of Barrett's carcinogenesis

Preclinical models of esophageal adenocarcinoma for drug development

Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junction

Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus.

Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers

TGF-beta signaling and its targeted therapy in gastrointestinal cancers

TRAIL-induced apoptosis is enhanced by heat shock protein 70 expression

The prognostic value of TP53 mutations in oesophageal adenocarcinoma: a systematic review and meta-analysis

Translational research on Barrett's esophagus.