Lista de obras - Alessandro Pini - Dominio Público Uruguay

A branched peptide mimotope of the nicotinic receptor binding site is a potent synthetic antidote against the snake neurotoxin alpha-bungarotoxin

scientific article published on 01 August 2002

A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors.

artículo científico publicado en 2014

A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo.

artículo científico publicado en 2009

An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue

scientific article published on 20 November 2019

Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification

artículo científico publicado en 2005

Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles

artículo científico publicado en 2019

Bioactive peptides from libraries.

artículo científico publicado en 2005

Biochemical filtering of a protein-protein docking simulation identifies the structure of a complex between a recombinant antibody fragment and alpha-bungarotoxin

artículo científico publicado en 2003

Branched peptides as therapeutics

artículo científico publicado en 2008

Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity.

artículo científico publicado en 2007

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

artículo científico publicado en 2017

D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

artículo científico publicado en 2015

Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.

artículo científico publicado en 2010

Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.

artículo científico publicado en 1998

Diagnostics of myasthenic syndromes: detection of anti-AChR and anti-MuSK antibodies

artículo científico publicado en 2017

Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions

artículo científico publicado en 2011

Esculentin(1-21), an amphibian skin membrane-active peptide with potent activity on both planktonic and biofilm cells of the bacterial pathogen Pseudomonas aeruginosa.

artículo científico publicado en 2013

Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action

artículo científico publicado en 2016

Hierarchical affinity maturation of a phage library derived antibody for the selective removal of cytomegalovirus from plasma.

artículo científico publicado en 1997

Immunomodulatory and Anti-inflammatory Activity in Vitro and in Vivo of a Novel Antimicrobial Candidate

scientific article published on 07 October 2016

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

artículo científico publicado en 2016

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

artículo científico publicado en 2016

Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

artículo científico publicado en 2017

Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

artículo científico publicado en 2012

Mimotopes of the nicotinic receptor binding site selected by a combinatorial peptide library.

artículo científico publicado en 2001

Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs

artículo científico publicado en 2016

Molecular basis of branched peptides resistance to enzyme proteolysis

artículo científico publicado en 2007

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging.

artículo científico publicado en 2018

Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.

artículo científico publicado en 2015

Oligo-branched peptides for tumor targeting: from magic bullets to magic forks

artículo científico publicado en 2009

Phage display and colony filter screening for high-throughput selection of antibody libraries.

artículo científico publicado en 2002

Phage display of antibody fragments.

artículo científico publicado en 2000

Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase

artículo científico publicado en 2014

Solubility improvement of an anthrax toxin peptide inhibitor by rational amino acid randomization.

artículo científico publicado en 2008

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

artículo científico publicado en 2006

Strategies for the construction and use of peptide and antibody libraries displayed on phages

artículo científico publicado en 2004

Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens

artículo científico publicado en 2017

Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting

artículo científico publicado en 2007

Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides

artículo científico publicado en 2011

The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.

artículo científico publicado en 2018

The development of antimicrobial peptides as new antibacterial drugs.

artículo científico publicado en 2013

The proteome speciation of an immortalized cystic fibrosis cell line: New perspectives on the pathophysiology of the disease.

artículo científico publicado en 2017

Tumor imaging with tetrabranched neurotensin.

artículo científico publicado en 2009

Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

artículo científico publicado en 2015

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

scientific article published on 18 September 2019

Lista de obras de Alessandro Pini

A branched peptide mimotope of the nicotinic receptor binding site is a potent synthetic antidote against the snake neurotoxin alpha-bungarotoxin

A novel phage-library-selected peptide inhibits human TNF-α binding to its receptors.

A novel tetrabranched antimicrobial peptide that neutralizes bacterial lipopolysaccharide and prevents septic shock in vivo.

An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue

Antimicrobial activity of novel dendrimeric peptides obtained by phage display selection and rational modification

Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles

Bioactive peptides from libraries.

Biochemical filtering of a protein-protein docking simulation identifies the structure of a complex between a recombinant antibody fragment and alpha-bungarotoxin

Branched peptides as therapeutics

Characterization of the branched antimicrobial peptide M6 by analyzing its mechanism of action and in vivo toxicity.

Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate

D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents.

Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel.

Diagnostics of myasthenic syndromes: detection of anti-AChR and anti-MuSK antibodies

Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions

Esculentin(1-21), an amphibian skin membrane-active peptide with potent activity on both planktonic and biofilm cells of the bacterial pathogen Pseudomonas aeruginosa.

Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action

Hierarchical affinity maturation of a phage library derived antibody for the selective removal of cytomegalovirus from plasma.

Immunomodulatory and Anti-inflammatory Activity in Vitro and in Vivo of a Novel Antimicrobial Candidate

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe

Investigations into the killing activity of an antimicrobial peptide active against extensively antibiotic-resistant K. pneumon iae and P. aeruginosa.

Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

Mimotopes of the nicotinic receptor binding site selected by a combinatorial peptide library.

Models of In-Vivo Bacterial Infections for the Development of Antimicrobial Peptide-based Drugs

Molecular basis of branched peptides resistance to enzyme proteolysis

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging.

Neurotensin branched peptide as a tumor-targeting agent for human bladder cancer.

Oligo-branched peptides for tumor targeting: from magic bullets to magic forks

Phage display and colony filter screening for high-throughput selection of antibody libraries.

Phage display of antibody fragments.

Site-specific pegylation of an antimicrobial peptide increases resistance to Pseudomonas aeruginosa elastase

Solubility improvement of an anthrax toxin peptide inhibitor by rational amino acid randomization.

Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo

Strategies for the construction and use of peptide and antibody libraries displayed on phages

Synergistic activity profile of an antimicrobial peptide against multidrug-resistant and extensively drug-resistant strains of Gram-negative bacterial pathogens

Synthesis and biological activity of stable branched neurotensin peptides for tumor targeting

Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides

The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.

The development of antimicrobial peptides as new antibacterial drugs.

The proteome speciation of an immortalized cystic fibrosis cell line: New perspectives on the pathophysiology of the disease.

Tumor imaging with tetrabranched neurotensin.

Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity