Lista de obras - Sam Alsford - Dominio Público Uruguay

A fluorescence in situ hybridisation study of the regulation of histone mRNA levels during the cell cycle of Trypanosoma brucei

artículo científico publicado en 1996

A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation.

artículo científico publicado en 2007

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

artículo científico publicado en 2013

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei

artículo científico publicado en 2014

Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei.

artículo científico publicado en 2012

Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei

artículo científico publicado en 2019

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.

scientific article published on 12 September 2016

Correction: Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes.

artículo científico publicado en 2015

Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA

artículo científico publicado en 2013

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

artículo científico publicado en 2013

DNA breaks as triggers for antigenic variation in African trypanosomes

artículo científico publicado en 2009

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

artículo científico publicado en 2018

Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest

artículo científico publicado en 2007

Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs

artículo científico publicado en 2017

Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes.

artículo científico

Genetic dissection of drug resistance in trypanosomes

artículo científico publicado en 2013

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes

artículo científico publicado en 2014

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6 ⬇️

artículo científico publicado el 18 de noviembre de 2010

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

artículo científico publicado en 2017

High-throughput decoding of antitrypanosomal drug efficacy and resistance

artículo científico publicado en 2012

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

artículo científico publicado en 2011

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis.

artículo científico publicado en 2014

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

artículo científico publicado en 2018

Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

artículo científico publicado en 2015

Multiplex analysis of RNA interference defects in Trypanosoma brucei

artículo científico publicado en 2005

NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions

artículo científico publicado en 2012

Nicotinic acetylcholine receptors on the surface of the blood fluke Schistosoma

scientific article published on 01 April 1995

Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei.

artículo científico publicado en 2017

RNA polymerase I transcription stimulates homologous recombination in Trypanosoma brucei.

artículo científico publicado en 2007

Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy.

artículo científico publicado en 2013

Segregation of minichromosomes in trypanosomes: implications for mitotic mechanisms

artículo científico publicado en 1998

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

artículo científico publicado en 2008

Subverting lysosomal function in Trypanosoma brucei

artículo científico publicado en 2015

Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects

artículo científico publicado en 2005

Trypanosomatid histones.

artículo científico publicado en 2004

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes.

artículo científico publicado en 2008

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

artículo científico publicado en 2016

Lista de obras de Sam Alsford

A fluorescence in situ hybridisation study of the regulation of histone mRNA levels during the cell cycle of Trypanosoma brucei

A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation.

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei

Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei.

Chemogenomic Profiling of Antileishmanial Efficacy and Resistance in the Related Kinetoplastid Parasite Trypanosoma brucei

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.

Correction: Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes.

Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

DNA breaks as triggers for antigenic variation in African trypanosomes

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest

Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs

Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes.

Genetic dissection of drug resistance in trypanosomes

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6 ⬇️

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

High-throughput decoding of antitrypanosomal drug efficacy and resistance

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis.

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

Multiplex analysis of RNA interference defects in Trypanosoma brucei

NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions

Nicotinic acetylcholine receptors on the surface of the blood fluke Schistosoma

Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei.

RNA polymerase I transcription stimulates homologous recombination in Trypanosoma brucei.

Receptor-mediated endocytosis for drug delivery in African trypanosomes: fulfilling Paul Ehrlich's vision of chemotherapy.

Segregation of minichromosomes in trypanosomes: implications for mitotic mechanisms

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

Subverting lysosomal function in Trypanosoma brucei

Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects

Trypanosomatid histones.

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes.

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes