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Lista de obras de Gianfranco Caselli

An HGF-MSP chimera disassociates the trophic properties of scatter factors from their pro-invasive activity.

artículo científico publicado en 2002

Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain

artículo científico publicado en 2011

Andolast acts at different cellular levels to inhibit immunoglobulin E synthesis.

artículo científico publicado en 2009

Antihistaminic/antiallergic activity of 2-dialkylaminoalkylthio(oxy)-1-substituted benzimidazoles: evaluation "in vitro" and "in vivo".

artículo científico publicado en 1990

CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma

scientific article published on 15 July 2021

CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats.

artículo científico publicado en 2012

CR4056, a powerful analgesic imidazoline-2 receptor ligand, inhibits the inflammation-induced PKCε phosphorylation and membrane translocation in sensory neurons

scientific article published on 07 November 2019

Dendrimeric tetravalent ligands for the serotonin-gated ion channel

artículo científico publicado en 2014

Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.

artículo científico publicado en 2008

Design, synthesis, and preliminary biological evaluation of pyrrolo[3,4-c]quinolin-1-one and oxoisoindoline derivatives as aggrecanase inhibitors.

artículo científico publicado en 2010

Discovery, synthesis, selectivity modulation and DMPK characterization of 5-azaspiro[2.4]heptanes as potent orexin receptor antagonists ⬇️

artículo científico publicado el 1 de mayo de 2013

Does colchicine really induce bone formation in the rodent bone Marrow? Yes, it does

artículo científico publicado en 1999

EFFICACY OF A NEW TOPICAL GEL-SPRAY FORMULATION OF KETOPROFEN LYSINE SALT IN THE RAT: PERCUTANEOUS PERMEATIONIN VITROANDIN VIVOAND PHARMACOLOGICAL ACTIVITY

artículo científico publicado en 1998

Effectiveness of carbocysteine lysine salt monohydrate on models of airway inflammation and hyperresponsiveness.

artículo científico publicado en 1995

Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis.

artículo científico publicado en 2017

Experimental pharmacology of glucosamine sulfate.

artículo científico

Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity

artículo científico publicado en 2013

Functional in vitro characterization of CR 3394: a novel voltage dependent N-methyl-D-aspartate (NMDA) receptor antagonist.

artículo científico publicado en 2005

IL-1 beta primes IL-8-activated human neutrophils for elastase release, phospholipase D activity, and calcium flux

artículo científico publicado en 1996

IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease

artículo científico publicado en 2003

Improved efficacy, tolerance, safety and abuse liability profile of the combination CR4056-morphine over morphine alone in rodent models

scientific article published on 10 March 2020

Lipopolysaccharide-induced lung injury in mice. I. Concomitant evaluation of inflammatory cells and haemorrhagic lung damage

artículo científico publicado en 2000

Lipopolysaccharide-induced lung injury in mice. II. Evaluation of functional damage in isolated parenchyma strips

scientific article published on 01 January 2000

Lps induces IL-6 in the brain and in serum largely through TNF production

scientific article published on 01 August 2000

Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats

artículo científico publicado en 2014

Multivalent ligands for the serotonin 5-HT receptor

artículo científico publicado en 2017

Multivalent supramolecular dendrimer-based drugs

artículo científico publicado en 2010

Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients

scientific article published on 01 October 1999

Pharmacokinetic study of a new angiotensin-AT1 antagonist by HPLC

artículo científico publicado en 2008

Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.

artículo científico publicado en 2018

Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity.

artículo científico publicado en 2004

Phenylindenone isomers as divergent modulators of p38α MAP kinase

artículo científico publicado en 2016

Progress towards the identification of new aggrecanase inhibitors

artículo científico publicado en 2009

Prostaglandins and lipolysis I: PGI2 formation by rat epididymal adipose tissue artery

scientific article published on 01 September 1981

Role of tumor necrosis factor-alpha in endotoxin-induced lung parenchymal hyporesponsiveness in mice

artículo científico publicado en 2001

Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers.

artículo científico publicado en 2001

Silibinin hemisuccinate binding to proteins in plasma and blood cell/plasma partitioning in mouse, rat, dog and man in vitro ⬇️

artículo científico publicado el 1 de enero de 2013

Supramolecular glycodendrimer-based hybrid drugs

artículo científico publicado en 2014

Synthesis and in vitro and in vivo evaluation of the 2-(6'methoxy-3',4'-dihydro-1'-naphtyl)-4H-3,1-benzoxazin-4- one as a new potent substrate inhibitor of human leukocyte elastase

artículo científico publicado en 1999

Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds

artículo científico publicado en 2013

Synthesis and structure-activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold

artículo científico publicado en 2014

Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones

artículo científico publicado en 2000

Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP4 receptor

artículo científico publicado en 2011

Targeting of ADAMTS5's ancillary domain with the recombinant mAb CRB0017 ameliorates disease progression in a spontaneous murine model of osteoarthritis ⬇️

artículo científico publicado el 15 de agosto de 2013

Tartronates: a new generation of drugs affecting bone metabolism

artículo científico publicado en 1997

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

artículo científico publicado en 2013

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