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Lista de obras de Jean-Marc Sabatier

A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels.

artículo científico publicado en 2003

A specific immunological probe for the major myelin proteolipid. Confirmation of a deletion in DM-20.

artículo científico publicado en 1986

Accessibility of the highly conserved amino- and carboxy-terminal regions from HIV-1 external envelope glycoproteins

artículo científico publicado en 1989

An anti-HIV peptide construct derived from the cleavage region of the Env precursor acts on Env fusogenicity through the presence of a functional cleavage sequence.

artículo científico publicado en 1998

Analysis of the interacting surface of maurotoxin with the voltage-gated Shaker B K(+) channel

artículo científico publicado en 2011

Animal venoms: from deadly arsenals (toxins) to therapeutic drug candidates.

artículo científico publicado en 2011

Anti-HIV activity of multibranched peptide constructs derived either from the cleavage sequence or from the transmembrane domain (gp41) of the human immunodeficiency virus type 1 envelope.

artículo científico publicado en 1996

Antibacterial Peptides

artículo científico publicado en 2020

Bacteriocins active against multi-resistant gram negative bacteria implicated in nosocomial infections.

artículo científico publicado en 2015

Bee Venom: Overview of Main Compounds and Bioactivities for Therapeutic Interests

scientific article published on 19 August 2019

Block of maurotoxin and charybdotoxin on human intermediate-conductance calcium-activated potassium channels (hIKCa1).

artículo científico publicado en 2004

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2.

artículo científico publicado en 2017

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

scientific article published on 30 June 2018

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5

scientific article published on 30 June 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6

scientific article published on 28 December 2019

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4

scientific article published on 31 December 2018

Cell penetration properties of a highly efficient mini maurocalcine Peptide

artículo científico publicado en 2013

Cell penetration properties of maurocalcine, a natural venom peptide active on the intracellular ryanodine receptor.

artículo científico publicado en 2006

Characterization of Am IT, an anti-insect β-toxin isolated from the venom of scorpion Androctonus mauretanicus

artículo científico publicado en 2015

Characterization of minor and major antigenic regions within the hepatitis B virus nucleocapsid.

artículo científico publicado en 1993

Chemical synthesis and characterization of J46 peptide, an atypical class IIa bacteriocin from Lactococcus lactis subsp. cremoris J46 Strain

scientific article published on 01 February 2008

Chemical synthesis and characterization of maurotoxin, a short scorpion toxin with four disulfide bridges that acts on K+ channels.

artículo científico publicado en 1996

Chemical synthesis and structure-activity relationships of Ts kappa, a novel scorpion toxin acting on apamin-sensitive SK channel

artículo científico publicado en 1999

Chemical synthesis, molecular modeling, and antimicrobial activity of a novel bacteriocin, MMFII

scientific article published on 01 November 2001

Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumor invasion

artículo científico publicado en 2015

Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels

artículo científico publicado en 2004

Comparison of the neurotoxic and myotoxic effects of two Moroccan scorpion venoms and their neutralization by experimental polyclonal antivenom.

artículo científico publicado en 2015

Contribution of the functional dyad of animal toxins acting on voltage-gated Kv1-type channels.

artículo científico publicado en 2005

Correspondences between the binding characteristics of a non-natural peptide, Lei-Dab7, and the distribution of SK subunits in the rat central nervous system.

artículo científico publicado en 2015

Cytotoxic effect on lymphocytes of Tat from human immunodeficiency virus (HIV-1).

artículo científico publicado en 1993

Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2.

artículo científico publicado en 2001

Design of a disulfide-less, pharmacologically inert, and chemically competent analog of maurocalcine for the efficient transport of impermeant compounds into cells.

artículo científico publicado en 2008

Differential effects of maurocalcine on Ca2+ release events and depolarization-induced Ca2+ release in rat skeletal muscle.

artículo científico publicado en 2005

Differential involvement of disulfide bridges on the folding of a scorpion toxin

artículo científico publicado en 1997

Disulfide bridge reorganization induced by proline mutations in maurotoxin.

artículo científico publicado en 2001

Diversity of folds in animal toxins acting on ion channels.

artículo científico publicado en 2004

Drug targets in viral infections

artículo científico publicado en 2009

Editorial

artículo científico publicado en 2016

Effect of Cu2+ on the oxidative folding of synthetic maurotoxin in vitro.

artículo científico publicado en 2008

Effect of maurotoxin, a four disulfide-bridged toxin from the chactoid scorpion Scorpio maurus, on Shaker K+ channels.

artículo científico publicado en 2000

Endogenous animal toxin-like human β-defensin 2 inhibits own K(+) channels through interaction with channel extracellular pore region.

artículo científico publicado en 2014

Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes

artículo científico publicado en 2014

Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins.

artículo científico publicado en 2004

Evolution of maurotoxin conformation and blocking efficacy towards Shaker B channels during the course of folding and oxidation in vitro

artículo científico publicado en 2002

Genetic Characterization of Lactic Acid Bacteria Isolated from Tunisian Milk Waste and their Antimicrobial Activity Against some Bacteria Implicated in Nosocomial Infections.

artículo científico publicado en 2016

Identification of a common domain in calmodulin-activated eukaryotic and bacterial adenylate cyclases

artículo científico publicado en 1989

Immunogenicity of the Human Immunodeficiency Virus (HIV) RecombinantnefGene Product. Mapping of T-Cell and B-Cell Epitopes in Immunized Chimpanzees

artículo científico publicado el 1 de septiembre de 1990

In vivo protection against Androctonus australis hector scorpion toxin and venom by immunization with a synthetic analog of toxin II.

artículo científico publicado en 1997

Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.

artículo científico publicado en 2005

Isolation, Characterization and Chemical Synthesis of Large Spectrum Antimicrobial Cyclic Dipeptide (l-leu-l-pro) from Streptomyces misionensisV16R3Y1 Bacteria Extracts. A Novel 1H NMR Metabolomic Approach

artículo científico publicado en 2020

K+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom.

artículo científico publicado en 2005

Lacticin LC14, a new bacteriocin produced by Lactococcus lactis BMG6.14: isolation, purification and partial characterization

scientific article published on 01 August 2012

Large fragments of nef-protein and gp110 envelope glycoprotein from HIV-1. Synthesis, CD analysis and immunoreactivity

artículo científico publicado en 1990

Lethal neurotoxicity in mice of the basic domains of HIV and SIV Rev proteins. Study of these regions by circular dichroism.

artículo científico publicado en 1991

Liposomal encapsulation enhances antiviral efficacy of SPC3 against human immunodeficiency virus type-1 infection in human lymphocytes.

artículo científico publicado en 2002

Maurocalcine and domain A of the II-III loop of the dihydropyridine receptor Cav 1.1 subunit share common binding sites on the skeletal ryanodine receptor.

artículo científico publicado en 2004

Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.

artículo científico publicado en 2003

Maurotoxin versus Pi1/HsTx1 scorpion toxins. Toward new insights in the understanding of their distinct disulfide bridge patterns.

artículo científico publicado en 2000

Maurotoxin: a potent inhibitor of intermediate conductance Ca2+-activated potassium channels.

artículo científico publicado en 2003

Mechanism of action and in vitro activity of short hybrid antimicrobial peptide PV3 against Pseudomonas aeruginosa.

artículo científico publicado en 2016

Mechanisms of maurotoxin action on Shaker potassium channels.

artículo científico publicado en 2000

Modelling of the III-IV loop, a domain involved in calcium channel Ca(v)2.1 inactivation, highlights a structural homology with the gamma subunit of G proteins.

artículo científico publicado en 2002

Modulators of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels and their Therapeutic Indications

artículo científico publicado en 2007

Molecular modeling and docking simulations of scorpion toxins and related analogs on human SKCa2 and SKCa3 channels

scientific article published on 19 April 2005

Monoclonal antibodies neutralizing the toxin II from Androctonus australis hector scorpion venom: usefulness of a synthetic, non-toxic analog

artículo científico publicado en 1997

Montivipera bornmuelleri Venom: Inhibitory Effect on Staphylococcus epidermidis and Escherichia coli F1F0-ATPases and Cytotoxicity on HCT116 Cancer Cell Lines

artículo científico publicado en 2021

Multi-branched peptides based on the HIV-1 V3 loop consensus motif inhibit HIV-1 and HIV-2 infection in CD4+ and CD4- cells

scientific article published on 01 November 1993

Novel Mutant Phospholipase D from Hemiscorpius lepturus Acts as A Highly Immunogen in BALB/c Mice Against the Lethality of Scorpion Venom

artículo científico publicado en 2020

Optimized Chemical Extraction Methods of Antimicrobial Peptides from Roots and Leaves of Extremophilic Plants: Anthyllis sericea and Astragalus armatus Collected from the Tunisian Desert

artículo científico publicado en 2022

Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion

artículo científico publicado en 2016

Pharmacological profiling of Orthochirus scrobiculosus toxin 1 analogs with a trimmed N-terminal domain

artículo científico publicado en 2006

Potential Inhibitory Effect of Apis mellifera's Venom and of Its Two Main Components-Melittin and PLA2-on Escherichia coli F1F0-ATPase

artículo científico publicado en 2020

Preface

Properties of HIV envelope expressed in the presence of SPC3, an Env-derived peptide drug under phase II clinical trials

scientific article published on 01 October 1998

Protein content analysis and antimicrobial activity of the crude venom of Montivipera bornmuelleri; a viper from Lebanon

artículo científico publicado en 2014

Protein-protein recognition control by modulating electrostatic interactions.

artículo científico publicado en 2010

Reduction and reoxidation of the neurotoxin II from the scorpion Androctonus australis Hector

artículo científico publicado en 1987

Relevance of anti-nef antibody detection as an early serologic marker of human immunodeficiency virus infection.

artículo científico publicado en 1990

Resistance of hepatitis C virus to NS3-4A protease inhibitors: mechanisms of drug resistance induced by R155Q, A156T, D168A and D168V mutations.

artículo científico publicado en 2006

SPC3, a synthetic peptide derived from the V3 domain of human immunodeficiency virus type 1 (HIV-1) gp120, inhibits HIV-1 entry into CD4+ and CD4- cells by two distinct mechanisms

artículo científico publicado en 1995

Small-conductance Ca2+-activated potassium type 2 channels regulate the formation of contextual fear memory.

artículo científico publicado en 2015

Solution structure of P05-NH2, a scorpion toxin analog with high affinity for the apamin-sensitive potassium channel

artículo científico publicado en 1993

Solution structure of TsKapa, a charybdotoxin-like scorpion toxin fromTityus serrulatus with high affinity for apamin-sensitive Ca2+-activated K+ channels

artículo científico publicado el 1 de noviembre de 1997

Solution structure of maurotoxin, a scorpion toxin fromScorpio maurus, with high affinity for voltage-gated potassium channels

artículo científico publicado el 1 de noviembre de 1997

Special Issue "Structure-Activity Relationship of Natural Products"

artículo científico publicado en 2017

Structure-activity relationship study of a scorpion toxin with high affinity for apamin-sensitive potassium channels by means of the solution structure of analogues

artículo científico publicado en 1995

Substance P receptor blockade decreases stretch-induced lung cytokines and lung injury in rats

scientific article published on 22 February 2010

Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells.

artículo científico publicado en 1994

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels.

artículo científico publicado en 2003

Synthesis and characterization of leiurotoxin I analogs lacking one disulfide bridge: evidence that disulfide pairing 3-21 is not required for full toxin activity

artículo científico publicado en 1996

Synthesis, 1H NMR structure, and activity of a three-disulfide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins

scientific article published on 01 May 2000

Synthetic multimeric peptides derived from the principal neutralization domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 bind to galactosylceramide and block HIV-1 infection in a human CD4-negative mucosal epithelial cell line

artículo científico publicado en 1995

Synthetic peptides as tools to investigate the structure and pharmacology of potassium channel-acting short-chain scorpion toxins

artículo científico publicado el 1 de febrero de 1998

The 'functional' dyad of scorpion toxin Pi1 is not itself a prerequisite for toxin binding to the voltage-gated Kv1.2 potassium channels.

artículo científico publicado en 2004

The Detection of Potential Native Probiotics Lactobacillus spp. against Salmonella Enteritidis, Salmonella Infantis and Salmonella Kentucky ST198 of Lebanese Chicken Origin

artículo científico publicado en 2022

The deciphered genome of Mesobuthus martensii uncovers the resistance mysteries of scorpion to its own venom and toxins at the ion channel level

artículo científico publicado en 2013

The impact of the fourth disulfide bridge in scorpion toxins of the α-KTx6 subfamily

artículo científico publicado en 2005

The interaction between the I-II loop and the III-IV loop of Cav2.1 contributes to voltage-dependent inactivation in a beta -dependent manner.

artículo científico publicado en 2002

Topology, Antiviral Functional Residues and Mechanism of IFITM1

artículo científico publicado en 2020

Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membrane

artículo científico publicado en 2005

Transient loss of voltage control of Ca2+ release in the presence of maurocalcine in skeletal muscle.

artículo científico publicado en 2006

Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues.

artículo científico publicado en 2014

Use of synthetic peptides for the detection of antibodies against the nef reguating protein in sera of HIV-infected patients

article

V3 loop-derived peptide SPC3 inhibits infection of CD4- and galactosylceramide- cells by LAV-2/B.

artículo científico publicado en 1999

Venoms of Iranian Scorpions (Arachnida, Scorpiones) and Their Potential for Drug Discovery

artículo científico publicado en 2019

Vipers of the Middle East: A Rich Source of Bioactive Molecules

[Chemical synthesis of lactococcin B and functional evaluation of the N-terminal domain using a truncated synthetic analogue]

artículo científico publicado en 2008