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Lista de obras de Sean M Davidson

116 Matrix metalloproteinase inhibition attenuates reperfusion injury, independently of and additive to mitochondrial permeability transition pore inhibition

16 Matrix metalloproteinase inhibition is a parallel pathway to protection against reperfusion injury, both independent and additive to mitochondrial permeability transition pore inhibition

162 Polymersomes Functionalized with HSP70 – Novel, Synthetic Cardioprotective Nanovesicles

162 Regulated Exosome Secretion by Vascular Smooth Muscle Cells Mediates Vascular Calcification

193 The role of the pi3k-alpha isoform in cardioprotection

253 REMOTE ISCHAEMIC PRECONDITIONING IS MEDIATED VIA THE SDF 1Α/CXCR4 SIGNALLING AXIS

9th Hatter Biannual Meeting: position document on ischaemia/reperfusion injury, conditioning and the ten commandments of cardioprotection

artículo científico publicado en 2016

A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development

scientific journal article

A needle in a haystack: focus on “Proteomic alterations of distinct mitochondrial subpopulations in the type 1 diabetic heart”

scientific article published on 01 December 2010

A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies.

artículo científico publicado en 2017

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

artículo científico publicado en 2018

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

artículo científico publicado en 2022

Apelin, the potentially therapeutic adipocytokine, protects against myocardial ischemia–reperfusion injury

article published in 2007

Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemiareperfusion injury

artículo científico publicado en 2007

Assessing Mitochondrial Potential, Calcium, and Redox State in Isolated Mammalian Cells Using Confocal Microscopy

artículo científico publicado en 2007

Biologically active constituents of the secretome of human W8B2+ cardiac stem cells.

artículo científico publicado en 2018

Calcium handling precedes cardiac differentiation to initiate the first heartbeat

artículo científico publicado en 2016

Calcium microdomains and oxidative stress

scientific article published on 17 October 2006

Can glucagon-like peptide-1 (GLP-1) analogues make neuroprotection a reality?

artículo científico publicado en 2020

Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro.

artículo científico publicado en 2017

Cardioprotection mediated by urocortin is dependent on PKCepsilon activation.

artículo científico publicado en 2005

Cardioprotection – is no the answer? A renewed look at nitric oxide signalling in cardiomyocytes

scientific article published on 01 May 2018

Cardioprotective actions of necrostatin

Cardioprotective actions of the novel adipocytokine visfatin

Circadian rhythms in ischaemic heart disease: key aspects for preclinical and translational research: position paper of the ESC working group on cellular biology of the heart

artículo científico publicado en 2021

Circulating blood cells and extracellular vesicles in acute cardioprotection

scientific article published on 01 June 2019

Co-dependence of the neural and humoral pathways in the mechanism of remote ischemic conditioning

artículo científico publicado en 2016

Comparison of small extracellular vesicles isolated from plasma by ultracentrifugation or size-exclusion chromatography: yield, purity and functional potential

Comparison of the effect of two different bone-targeted radiofrequency ablation (RFA) systems alone and in combination with percutaneous vertebroplasty (PVP) on the biomechanical stability of the metastatic spine

artículo científico publicado en 2015

Confounding factors in vesicle uptake studies using fluorescent lipophilic membrane dyes

artículo científico publicado en 2017

Correction: Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury.

artículo científico publicado en 2013

Corrigendum to “Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway” [Biochem. Biophys. Res. Commun. 328 (2005) 442–448]

scholarly article published in Biochemical and Biophysical Research Communications

Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system

artículo científico publicado el 1 de enero de 1992

DJ-1 protects against cell death following acute cardiac ischemia-reperfusion injury.

artículo científico publicado en 2014

David Garcia-Dorado: a true pioneer in cardiac ischaemia/reperfusion injury

artículo científico publicado en 2019

De novo cardiomyocytes from within the activated adult heart after injury

artículo científico publicado en 2011

Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism.

artículo científico publicado en 2015

Dissecting out the mechanism of cardioprotection by endogenous erthyropoietin using genetic engineering

artículo científico publicado en 2006

Does Hyperglycemia Reduce Proliferation or Increase Apoptosis?

artículo científico publicado en 2006

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure

artículo científico publicado en 2019

ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies

artículo científico publicado en 2014

Editorial to: "Building a Bridge to the Future of Cardiovascular Drugs and Therapy".

artículo científico publicado en 2017

Effects of NO on mitochondrial function in cardiomyocytes: Pathophysiological relevance

artículo científico publicado en 2006

Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning

artículo científico publicado en 2018

Endothelial insulin resistance protects the heart against prolonged ischemia-reperfusion injury but does not prevent insulin transport across the endothelium in a mouse Langendorff model.

artículo científico publicado en 2014

Endothelial mitochondria and heart disease

artículo científico publicado en 2010

Endothelial mitochondria: contributing to vascular function and disease

artículo científico publicado en 2007

Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury

artículo científico publicado en 2011

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

artículo científico publicado en 2017

Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3.

artículo científico publicado en 2012

Exogenous Administration of Recombinant MIF at Physiological Concentrations Failed to Attenuate Infarct Size in a Langendorff Perfused Isolated Mouse Heart Model

scientific article published on 22 June 2016

Exogenous SDF-1α Protects Human Myocardium from Hypoxia-Reoxygenation Injury via CXCR4.

artículo científico publicado en 2015

Exosomes and Cardiovascular Protection.

artículo científico publicado en 2016

Exosomes and cardioprotection - A critical analysis

artículo científico publicado en 2017

Exosomes: nanoparticles involved in cardioprotection?

artículo científico

Extracellular histones are a target in myocardial ischaemia-reperfusion injury

artículo científico publicado en 2022

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology.

artículo científico publicado en 2018

FAM3A - A mitochondrial route to the stimulation of angiogenesis?

artículo científico publicado en 2019

FLIP protects cardiomyocytes from apoptosis induced by simulated ischemia/reoxygenation, as demonstrated by short hairpin-induced (shRNA) silencing of FLIP mRNA

scientific journal article

Failure of the Adipocytokine, Resistin, to Protect the Heart From Ischemia-Reperfusion Injury

artículo científico publicado en 2010

Fantastic beasts and how to find them-Molecular identification of the mitochondrial ATP-sensitive potassium channel

scientific article published on 15 October 2019

Flagging flora: heart disease link

scientific article published on 07 September 2011

From Protecting the Heart to Improving Athletic Performance - the Benefits of Local and Remote Ischaemic Preconditioning.

artículo científico publicado en 2015

Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse

artículo científico publicado en 2008

HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore.

artículo científico publicado en 2014

High on the hog

artículo científico publicado en 2010

Hsp25 and the p38 MAPK pathway are involved in differentiation of cardiomyocytes.

artículo científico publicado en 2000

Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway

scientific journal article

Imaging Mitochondrial Calcium Fluxes with Fluorescent Probes and Single- or Two-Photon Confocal Microscopy

artículo científico publicado en 2018

Imaging Mitochondrial Calcium Signalling with Fluorescent Probes and Single or Two Photon Confocal Microscopy

artículo científico publicado en 2012

Increased production of functional small extracellular vesicles in senescent endothelial cells

artículo científico publicado en 2020

Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury

artículo científico publicado en 2010

Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.

artículo científico publicado en 2015

Innate immunity as a target for acute cardioprotection

scientific article published on 01 June 2019

Interaction of Cardiovascular Nonmodifiable Risk Factors, Comorbidities and Comedications With Ischemia/Reperfusion Injury and Cardioprotection by Pharmacological Treatments and Ischemic Conditioning

artículo científico publicado en 2022

Interaction of the heart and its close and distant neighbours: report of the Meeting of the ESC Working Groups Myocardial Function and Cellular Biology

artículo científico publicado en 2013

Intrinsic cardiac ganglia and acetylcholine are important in the mechanism of ischaemic preconditioning.

artículo científico publicado en 2017

Ischaemic Preconditioning Protects Cardiomyocytes from Anthracycline-Induced Toxicity via the PI3K Pathway.

artículo científico publicado en 2018

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

artículo científico publicado en 2014

Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

artículo científico publicado en 2016

Leptin, the obesity-related adipocytokine, protects the myocardium against ischaemia–reperfusion injury

Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore

artículo científico publicado en 2010

Leptin-stimulated inhibition of mitochondrial permeability transition is dependent on presence of functional OB-RB leptin receptor

Letter by Takov et al Regarding Article, "Fabrication of Synthetic Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice".

artículo científico publicado en 2017

Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors

scientific journal article

Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.

artículo científico publicado en 2013

Matrix metalloproteinase inhibition protects CyPD knockout mice independently of RISK/mPTP signalling: a parallel pathway to protection.

artículo científico publicado en 2013

Melatonin as a cardioprotective therapy following ST-segment elevation myocardial infarction: is it really promising? Reply.

artículo científico publicado en 2017

Metformin cardioprotects the diabetic heart by inhibiting mPTP opening via the risk pathway

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

artículo científico publicado en 2009

Metformin protects against myocardial reperfusion injury via PI3-kinase-dependent inhibition of mitochondrial permeability transition

Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening

artículo científico publicado en 2007

Microvesicles and Exosomes in Local and Distant Communication with the Heart

Microvesicles and exosomes: new players in metabolic and cardiovascular disease

artículo científico publicado en 2016

Mitochondrial DNA damage, oxidative stress, and atherosclerosis: where there is smoke there is not always fire

artículo científico publicado en 2013

Mitochondrial PINK1--a novel cardioprotective kinase?

artículo científico publicado en 2008

Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury

scientific article published on 10 March 2020

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning

artículo científico publicado en 2010

Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure

artículo científico publicado en 2011

Mitochondrial pharmacology: energy, injury and beyond.

artículo científico publicado en 2014

Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation

Molecular regulation of cardiac hypertrophy

artículo científico publicado en 2008

Monitoring dynamic changes in lymph metabolome of fasting and fed rats by electrospray ionization-ion mobility mass spectrometry (ESI-IMMS).

artículo científico publicado en 2009

Mouse models of atherosclerosis and their suitability for the study of myocardial infarction

artículo científico publicado en 2020

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week

scientific article published on 01 January 2019

Myocardial regeneration: expanding the repertoire of thymosin β4 in the ischemic heart

artículo científico publicado en 2012

Necrostatin: a potentially novel cardioprotective agent?

artículo científico publicado en 2007

Neural mechanisms in remote ischaemic conditioning in the heart and brain: mechanistic and translational aspects.

artículo científico publicado en 2018

Neuroprotection in Rats Following Ischaemia-Reperfusion Injury by GLP-1 Analogues-Liraglutide and Semaglutide

scientific article published on 01 December 2019

New insights into cardiotoxicity caused by chemotherapeutic agents

artículo científico publicado en 2017

Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

artículo científico publicado en 2017

Novel therapeutic strategies for cardioprotection.

artículo científico

Optical delivery and monitoring of photodynamic therapy of prostate cancer

Over-expression of the cardioprotective kinase Akt modulates mitochondrial morphology

P439Comparative metabolomics identifies conserved metabolic pathways that control mitochondrial ROS production during ischaemia reperfusion injury

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

artículo científico publicado en 2004

Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells

artículo científico publicado en 2012

Plasma exosomes protect the myocardium from ischemia-reperfusion injury.

artículo científico publicado en 2015

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

artículo científico publicado en 2016

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

artículo científico publicado en 2018

Preconditioning and postconditioning: The essential role of the mitochondrial permeability transition pore

Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore

artículo científico publicado en 2007

Protection From Cardiac Ischemia-Reperfusion Injury by Epigenetic Regulation of NADPH Oxidase

artículo científico publicado en 2018

Reflections on 40 years of the British Society for Cardiovascular Research (BSCR).

artículo científico publicado en 2013

Remote ischaemic conditioning reduces infarct size in animal in vivo models of ischaemia-reperfusion injury: a systematic review and meta-analysis

artículo científico publicado en 2016

Remote ischaemic preconditioning involves signalling through the SDF-1α/CXCR4 signalling axis

artículo científico publicado en 2013

Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop

artículo científico publicado en 2015

Response to "Causal reasoning: the 'magical number' three"

artículo científico publicado en 2009

Rho-kinase mediates reoxygenation-induced cardiomyocyte death and promotes mitochondrial transition pore opening

Role of Caspase 1 in Ischemia/Reperfusion Injury of the Myocardium

artículo científico publicado en 2019

Role of PI3K in myocardial ischaemic preconditioning: mapping pro-survival cascades at the trigger phase and at reperfusion

artículo científico publicado en 2017

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage

artículo científico publicado en 2005

STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis

artículo científico publicado en 2003

STAT5 fits the RISK profile for cardioprotection

artículo científico publicado en 2012

Shining the spotlight on cardioprotection: beyond the cardiomyocyte

artículo científico publicado en 2019

Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection

artículo científico publicado en 2005

Silencing PTEN, a negative regulator of the PI3K/AKT pathway, is not sufficient to confer protection against simulated ischaemia and reperfusion

Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation

artículo científico publicado en 2011

Small extracellular vesicles secreted from human amniotic fluid mesenchymal stromal cells possess cardioprotective and promigratory potential

artículo científico publicado en 2020

Stem Cell Aging and Age-Related Cardiovascular Disease: Perspectives of Treatment by Ex-vivo Stem Cell Rejuvenation.

artículo científico publicado en 2014

Stromal cell-derived factor-1α signals via the endothelium to protect the heart against ischaemia-reperfusion injury

scientific article published on 07 February 2019

Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium.

artículo científico publicado en 2014

TPC1 Knockout Knocks Out TPC1.

artículo científico publicado en 2015

Targeting myocardial ischaemic injury in the absence of reperfusion

scientific article published on 14 October 2020

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology

scientific article published on 11 October 2018

The Caspase 1 Inhibitor VX-765 Protects the Isolated Rat Heart via the RISK Pathway.

artículo científico publicado en 2018

The GTN patch: a simple and effective new approach to cardioprotection?

artículo científico publicado en 2018

The Role of Extracellular DNA and Histones in Ischaemia-Reperfusion Injury of the Myocardium

scientific article published on 01 February 2020

The adipocytokine, resistin, is not cardioprotective despite activating components of the risk pathway

The cannabinoid CB1 receptor antagonist, rimonabant, protects against acute myocardial infarction.

artículo científico publicado en 2009

The cardioprotective actions of leptin are lost in the Zucker obese (fa/fa) rat.

artículo científico publicado en 2009

The cardioprotective effect of atorvastatin—Is there a role for the adenosine receptor?

The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage

artículo científico publicado en 2004

The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection

scientific article published on 01 June 2019

The cytokine storm of COVID-19: a spotlight on prevention and protection

artículo científico publicado en 2020

The developmental expression of small HSP.

artículo científico publicado en 2002

The effect of Cyclosporine A on cardiomyocytes differentiation

artículo científico publicado en 2007

The importance of clinically relevant background therapy in cardioprotective studies

artículo científico publicado en 2020

The mitochondrial permeability transition pore as a target for cardioprotection in hypertrophic cardiomyopathy.

artículo científico publicado en 2013

The novel adipocytokine visfatin exerts direct cardioprotective effects

artículo científico publicado en 2008

The powerful cardioprotective effects of urocortin and the corticotropin releasing hormone (CRH) family

artículo científico publicado en 2008

The role of PI3Kα isoform in cardioprotection

artículo científico publicado en 2017

The role of nitric oxide in mitochondria. Focus on “Modulation of mitochondrial Ca2+ by nitric oxide in cultured bovine vascular endothelial cells”

scientific article published on 01 October 2005

The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin

scientific journal article

Title: Therapeutic strategies utilising SDF-1α in ischaemic cardiomyopathy.

artículo científico publicado en 2017

Transgenic overexpression of HSP56 does not result in cardiac hypertrophy nor protect from ischaemia/reperfusion injury

artículo científico publicado en 2010

Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction

artículo científico publicado en 2010

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

artículo científico publicado en 2010

Trials, tribulations and speculation! Report from the 7th Biennial Hatter Cardiovascular Institute Workshop

artículo científico publicado en 2012

UK-Russia Researcher Links Workshop: extracellular vesicles - mechanisms of biogenesis and roles in disease pathogenesis, M.V. Lomonosov Moscow State University, Moscow, Russia, 1-5 March 2015

artículo científico publicado en 2015

Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress

artículo científico publicado en 2007

Urocortin: a few inflammatory remarks.

artículo científico publicado en 2009

Urocortin: a protective peptide that targets both the myocardium and vasculature

artículo científico publicado en 2009

Using multiphoton microscopy to examine the response of the heart to ischaemia and reperfusion injury

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion.

artículo científico publicado en 2015

Ventilation strategy has a major influence on remote ischaemic preconditioning in mice

artículo científico publicado en 2017

miR-19a-3p containing exosomes improve function of ischaemic myocardium upon shock wave therapy

scientific article published on 13 August 2019

β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.

artículo científico publicado en 2014

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