Lista de obras - Alberto Luini - Dominio Público Uruguay

A 14-3-3γ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIIIβ to regulate post-Golgi carrier formation.

artículo científico publicado en 2012

A randomized trial of low-dose tamoxifen on breast cancer proliferation and blood estrogenic biomarkers

artículo científico publicado en 2003

A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway.

artículo científico publicado en 2008

ADP ribosylation factor regulates spectrin binding to the Golgi complex ⬇️

artículo científico publicado el 21 de julio de 1998

ARFGAP1 promotes AP-2-dependent endocytosis.

artículo científico publicado en 2011

Actin dynamics at sites of extracellular matrix degradation.

artículo científico publicado en 2006

Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation

artículo científico publicado en 2011

Analogs of the Golgi complex in microsporidia: structure and avesicular mechanisms of function.

artículo científico publicado en 2007

Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial

scientific article published on 11 March 2013

Breast phyllodes tumor: a review of literature and a single center retrospective series analysis

artículo científico

Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation

artículo científico publicado en 2014

Characterization of chemical inhibitors of brefeldin A-activated mono-ADP-ribosylation.

artículo científico publicado en 1997

Components of the CtBP1/BARS-dependent fission machinery.

artículo científico publicado en 2013

Conservative surgery in patients with multifocal/multicentric breast cancer

artículo científico publicado en 2008

Constitutive transport between the trans-Golgi network and the plasma membrane according to the maturation model. A hypothesis

scientific article published on 01 November 1998

Control systems of membrane transport at the interface between the endoplasmic reticulum and the Golgi

artículo científico publicado en 2014

Correlation of 4Pi and electron microscopy to study transport through single Golgi stacks in living cells with super resolution.

artículo científico publicado en 2009

Correlative video-light-electron microscopy: development, impact and perspectives.

artículo científico

CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission

artículo científico publicado en 2003

CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization

artículo científico publicado en 2009

CtBP3/BARS drives membrane fission in dynamin-independent transport pathways

artículo científico publicado en 2005

Cyclosporin A, but not FK506, increases arachidonic acid release and inhibits proliferation of pituitary corticotrope tumor cells.

artículo científico publicado en 1999

Cytosolic phospholipase A₂ε drives recycling through the clathrin-independent endocytic route

scientific article published on 10 January 2014

Dicumarol, an inhibitor of ADP-ribosylation of CtBP3/BARS, fragments golgi non-compact tubular zones and inhibits intra-golgi transport

artículo científico publicado en 2004

ER-to-Golgi carriers arise through direct en bloc protrusion and multistage maturation of specialized ER exit domains

artículo científico publicado en 2003

Functional dissociation between glucocorticoid-induced decrease in arachidonic acid release and inhibition of adrenocorticotropic hormone secretion in AtT-20 corticotrophs.

artículo científico publicado en 1997

Glucocorticoid stabilization of actin filaments: a possible mechanism for inhibition of corticotropin release ⬇️

artículo científico publicado el 1 de mayo de 1992

Golgi enzymes are enriched in perforated zones of golgi cisternae but are depleted in COPI vesicles.

artículo científico publicado en 2004

Golgi-dependent signaling: self-coordination of membrane trafficking.

artículo científico publicado en 2013

Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport

artículo científico publicado en 2009

Heterogeneity of triple-negative breast cancer: histologic subtyping to inform the outcome.

artículo científico publicado en 2012

High-dose-rate Brachytherapy as Adjuvant Local rEirradiation for Salvage Treatment of Recurrent breAst cancer (BALESTRA): a retrospective mono-institutional study

artículo científico publicado en 2020

Immunohistochemically defined subtypes and outcome in occult breast carcinoma with axillary presentation.

artículo científico publicado en 2011

Immunohistochemically defined subtypes and outcome of apocrine breast cancer

artículo científico publicado en 2012

Increasing steroid hormone receptors expression defines breast cancer subtypes non responsive to preoperative chemotherapy

artículo científico publicado en 2008

Intermittent Letrozole Administration as Adjuvant Endocrine Therapy for Postmenopausal Women With Hormone Receptor-Positive Early Breast Cancer: A Biologic Study

artículo científico publicado en 2015

Intracellular processing and activation of membrane type 1 matrix metalloprotease depends on its partitioning into lipid domains.

artículo científico publicado en 2004

Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: prognostic implications of EGFR immunoreactivity

artículo científico publicado en 2008

Invasive lobular breast cancer: subtypes and outcome

artículo científico publicado en 2012

Lack of prognostic significance of “classic” lobular breast carcinoma: a matched, single institution series

Large pleiomorphic traffic intermediates in the secretory pathway.

artículo científico publicado en 2005

Letrozole plus GnRH analogue as preoperative and adjuvant therapy in premenopausal women with ER positive locally advanced breast cancer.

artículo científico publicado en 2011

Male breast cancer: a special therapeutic problem. Anything new? (Review).

artículo científico publicado en 2004

Mechanism of constitutive export from the golgi: bulk flow via the formation, protrusion, and en bloc cleavage of large trans-golgi network tubular domains.

artículo científico publicado en 2003

Metronomic chemotherapy combined with bevacizumab and erlotinib in patients with metastatic HER2-negative breast cancer: clinical and biological activity.

artículo científico publicado en 2012

Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling

artículo científico publicado en 2015

Mitotic Golgi partitioning is driven by the membrane-fissioning protein CtBP3/BARS.

artículo científico publicado en 2004

Models for Golgi traffic: a critical assessment

artículo científico publicado en 2011

Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.

artículo científico publicado en 1999

Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS.

artículo científico publicado en 2013

Morphogenesis of post-Golgi transport carriers

artículo científico publicado en 2008

Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation.

artículo científico publicado en 2008

Nonrandomized comparison between concomitant and sequential chemoradiotherapy with anthracyclines in breast cancer

artículo científico publicado en 2015

Outcomes of patients with breast cancer who present with ipsilateral supraclavicular or internal mammary lymph node metastases.

artículo científico publicado en 2013

PDMP blocks the BFA-induced ADP-ribosylation of BARS-50 in isolated Golgi membranes

artículo científico publicado en 1999

Passage through the Golgi.

artículo científico publicado en 2010

Pathological complete response after preoperative systemic therapy and outcome: relevance of clinical and biologic baseline features

artículo científico publicado en 2010

Pathological features and survival outcomes of very young patients with early breast cancer: how much is "very young"?

artículo científico publicado en 2013

Pegylated liposomal doxorubicin in combination with low-dose metronomic cyclophosphamide as preoperative treatment for patients with locally advanced breast cancer

artículo científico publicado en 2011

Phase II trial of combination of pegylated liposomal doxorubicin, cisplatin, and infusional 5-fluorouracil (CCF) plus trastuzumab as preoperative treatment for locally advanced and inflammatory breast cancer.

artículo científico publicado en 2010

Preoperative concurrent chemo- and endocrine therapies for women with large operable breast cancer expressing steroid hormone receptors

artículo científico publicado en 2008

Preoperative therapy with trastuzumab and oral vinorelbine (+/- endocrine therapy) in patients with HER2-positive breast cancer

artículo científico publicado en 2010

Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.

artículo científico publicado en 2016

Procollagen Traverses the Golgi Stack without Leaving the Lumen of Cisternae

artículo científico publicado en 1998

Proposed new clinicopathological surrogate definitions of luminal A and luminal B (HER2-negative) intrinsic breast cancer subtypes

artículo científico publicado en 2014

Purification and functional properties of the membrane fissioning protein CtBP3/BARS

artículo científico publicado en 2005

Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex.

artículo científico publicado en 1993

Regulation of Golgi signaling and trafficking by the KDEL receptor.

artículo científico

Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells

artículo científico publicado en 2014

Role of NAD+ and ADP-ribosylation in the maintenance of the Golgi structure.

artículo científico publicado en 1997

Second malignancies following breast cancer treatment: a case-control study based on the Peridose methodology. Allegro project (task 5.4).

artículo científico publicado en 2012

Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments.

artículo científico publicado en 2004

Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial

artículo científico publicado en 2023

Signaling Circuits on the Golgi Complex ⬇️

artículo científico publicado el 15 de noviembre de 2012

Signaling at the Golgi: sensing and controlling the membrane fluxes.

artículo científico publicado en 2016

Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae

artículo científico publicado en 2001

Tailored preoperative treatment of locally advanced triple negative (hormone receptor negative and HER2 negative) breast cancer with epirubicin, cisplatin, and infusional fluorouracil followed by weekly paclitaxel.

artículo científico publicado en 2007

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

artículo científico publicado en 2012

The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured

artículo científico publicado en 2006

The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment ⬇️

artículo científico publicado el 1 de diciembre de 2001

The Golgi complex

artículo científico publicado en 2009

The Golgi mitotic checkpoint is controlled by BARS-dependent fission of the Golgi ribbon into separate stacks in G2.

artículo científico publicado en 2007

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS.

artículo científico publicado en 2008

The physiology of membrane transport and endomembrane-based signalling

artículo científico publicado en 2006

Trans-membrane area asymmetry controls the shape of cellular organelles

artículo científico publicado en 2015

Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae

artículo científico publicado en 2014

Unravelling druggable signalling networks that control F508del-CFTR proteostasis

artículo científico publicado en 2015

Variations on the Intracellular Transport Theme: Maturing Cisternae and Trafficking Tubules ⬇️

artículo científico publicado el 11 de agosto de 1997

Visualizing live dynamics and ultrastructure of intracellular organelles with preembedding correlative light-electron microscopy.

artículo científico publicado en 2012

Visualizing membrane traffic in vivo by combined video fluorescence and 3D electron microscopy

artículo científico publicado en 2000

Lista de obras de Alberto Luini

A 14-3-3γ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIIIβ to regulate post-Golgi carrier formation.

A randomized trial of low-dose tamoxifen on breast cancer proliferation and blood estrogenic biomarkers

A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway.

ADP ribosylation factor regulates spectrin binding to the Golgi complex ⬇️

ARFGAP1 promotes AP-2-dependent endocytosis.

Actin dynamics at sites of extracellular matrix degradation.

Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation

Analogs of the Golgi complex in microsporidia: structure and avesicular mechanisms of function.

Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial

Breast phyllodes tumor: a review of literature and a single center retrospective series analysis

Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation

Characterization of chemical inhibitors of brefeldin A-activated mono-ADP-ribosylation.

Components of the CtBP1/BARS-dependent fission machinery.

Conservative surgery in patients with multifocal/multicentric breast cancer

Constitutive transport between the trans-Golgi network and the plasma membrane according to the maturation model. A hypothesis

Control systems of membrane transport at the interface between the endoplasmic reticulum and the Golgi

Correlation of 4Pi and electron microscopy to study transport through single Golgi stacks in living cells with super resolution.

Correlative video-light-electron microscopy: development, impact and perspectives.

CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission

CtBP1/BARS Gly172-->Glu mutant structure: impairing NAD(H)-binding and dimerization

CtBP3/BARS drives membrane fission in dynamin-independent transport pathways

Cyclosporin A, but not FK506, increases arachidonic acid release and inhibits proliferation of pituitary corticotrope tumor cells.

Cytosolic phospholipase A₂ε drives recycling through the clathrin-independent endocytic route

Dicumarol, an inhibitor of ADP-ribosylation of CtBP3/BARS, fragments golgi non-compact tubular zones and inhibits intra-golgi transport

ER-to-Golgi carriers arise through direct en bloc protrusion and multistage maturation of specialized ER exit domains

Functional dissociation between glucocorticoid-induced decrease in arachidonic acid release and inhibition of adrenocorticotropic hormone secretion in AtT-20 corticotrophs.

Glucocorticoid stabilization of actin filaments: a possible mechanism for inhibition of corticotropin release ⬇️

Golgi enzymes are enriched in perforated zones of golgi cisternae but are depleted in COPI vesicles.

Golgi-dependent signaling: self-coordination of membrane trafficking.

Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport

Heterogeneity of triple-negative breast cancer: histologic subtyping to inform the outcome.

High-dose-rate Brachytherapy as Adjuvant Local rEirradiation for Salvage Treatment of Recurrent breAst cancer (BALESTRA): a retrospective mono-institutional study

Immunohistochemically defined subtypes and outcome in occult breast carcinoma with axillary presentation.

Immunohistochemically defined subtypes and outcome of apocrine breast cancer

Increasing steroid hormone receptors expression defines breast cancer subtypes non responsive to preoperative chemotherapy

Intermittent Letrozole Administration as Adjuvant Endocrine Therapy for Postmenopausal Women With Hormone Receptor-Positive Early Breast Cancer: A Biologic Study

Intracellular processing and activation of membrane type 1 matrix metalloprotease depends on its partitioning into lipid domains.

Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: prognostic implications of EGFR immunoreactivity

Invasive lobular breast cancer: subtypes and outcome

Lack of prognostic significance of “classic” lobular breast carcinoma: a matched, single institution series

Large pleiomorphic traffic intermediates in the secretory pathway.

Letrozole plus GnRH analogue as preoperative and adjuvant therapy in premenopausal women with ER positive locally advanced breast cancer.

Male breast cancer: a special therapeutic problem. Anything new? (Review).

Mechanism of constitutive export from the golgi: bulk flow via the formation, protrusion, and en bloc cleavage of large trans-golgi network tubular domains.

Metronomic chemotherapy combined with bevacizumab and erlotinib in patients with metastatic HER2-negative breast cancer: clinical and biological activity.

Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling

Mitotic Golgi partitioning is driven by the membrane-fissioning protein CtBP3/BARS.

Models for Golgi traffic: a critical assessment

Molecular cloning and functional characterization of brefeldin A-ADP-ribosylated substrate. A novel protein involved in the maintenance of the Golgi structure.

Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS.

Morphogenesis of post-Golgi transport carriers

Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation.

Nonrandomized comparison between concomitant and sequential chemoradiotherapy with anthracyclines in breast cancer

Outcomes of patients with breast cancer who present with ipsilateral supraclavicular or internal mammary lymph node metastases.

PDMP blocks the BFA-induced ADP-ribosylation of BARS-50 in isolated Golgi membranes

Passage through the Golgi.

Pathological complete response after preoperative systemic therapy and outcome: relevance of clinical and biologic baseline features

Pathological features and survival outcomes of very young patients with early breast cancer: how much is "very young"?

Pegylated liposomal doxorubicin in combination with low-dose metronomic cyclophosphamide as preoperative treatment for patients with locally advanced breast cancer

Phase II trial of combination of pegylated liposomal doxorubicin, cisplatin, and infusional 5-fluorouracil (CCF) plus trastuzumab as preoperative treatment for locally advanced and inflammatory breast cancer.

Preoperative concurrent chemo- and endocrine therapies for women with large operable breast cancer expressing steroid hormone receptors

Preoperative therapy with trastuzumab and oral vinorelbine (+/- endocrine therapy) in patients with HER2-positive breast cancer

Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.

Procollagen Traverses the Golgi Stack without Leaving the Lumen of Cisternae

Proposed new clinicopathological surrogate definitions of luminal A and luminal B (HER2-negative) intrinsic breast cancer subtypes

Purification and functional properties of the membrane fissioning protein CtBP3/BARS

Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex.

Regulation of Golgi signaling and trafficking by the KDEL receptor.

Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells

Role of NAD+ and ADP-ribosylation in the maintenance of the Golgi structure.

Second malignancies following breast cancer treatment: a case-control study based on the Peridose methodology. Allegro project (task 5.4).

Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments.

Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial

Signaling Circuits on the Golgi Complex ⬇️

Signaling at the Golgi: sensing and controlling the membrane fluxes.

Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae

Tailored preoperative treatment of locally advanced triple negative (hormone receptor negative and HER2 negative) breast cancer with epirubicin, cisplatin, and infusional fluorouracil followed by weekly paclitaxel.

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator

The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured