Lista de obras - William T Festuccia - Dominio Público Uruguay

11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues

artículo científico publicado en 2007

A comparative perspective on lipid storage in animals

artículo científico publicado en 2013

A novel peptide that improves metabolic parameters without adverse central nervous system effects.

artículo científico publicado en 2017

Adaptation to a high protein, carbohydrate-free diet induces a marked reduction of fatty acid synthesis and lipogenic enzymes in rat adipose tissue that is rapidly reverted by a balanced diet.

artículo científico publicado en 2005

Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.

artículo científico publicado en 2017

Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice

artículo científico publicado en 2021

Basal adrenergic tone is required for maximal stimulation of rat brown adipose tissue UCP1 expression by chronic PPAR-gamma activation.

artículo científico publicado en 2010

Brown adipose tissue glyceroneogenesis is activated in rats exposed to cold.

artículo científico publicado en 2004

Cagaita fruit (Eugenia dysenterica DC.) and obesity: Role of polyphenols on already established obesity

artículo científico publicado en 2017

Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue ⬇️

artículo científico publicado en 2010

Constitutive Activation of the Nutrient Sensor mTORC1 in Myeloid Cells Induced by Tsc1 Deletion Protects Mice from Diet-Induced Obesity

artículo científico publicado en 2018

Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.

artículo científico publicado en 2016

Control of Brown Adipose Tissue Glucose and Lipid Metabolism by PPARγ.

artículo científico

Critical review of beige adipocyte thermogenic activation and contribution to whole-body energy expenditure

artículo científico publicado en 2017

DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.

artículo científico publicado en 2012

Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.

artículo científico publicado en 2017

Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide

artículo científico publicado en 2019

Depletion of Ric-8B leads to reduced mTORC2 activity

scientific article published on 11 May 2020

Depot-specific effects of the PPARgamma agonist rosiglitazone on adipose tissue glucose uptake and metabolism.

artículo científico publicado en 2009

Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1

artículo científico publicado en 2007

Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects

artículo científico publicado en 2019

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

artículo científico publicado en 2020

Eicosapentaenoic Acid Reduces Adiposity, Glucose Intolerance and Increases Oxygen Consumption Independently of Uncoupling Protein 1

artículo científico publicado en 2019

Exercise rescues the immune response fine-tuned impaired by peroxisome proliferator-activated receptors γ deletion in macrophages

scientific article published on 21 September 2018

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

artículo científico publicado en 2016

Fish Oil Protects Wild Type and Uncoupling Protein 1-Deficient Mice from Obesity and Glucose Intolerance by Increasing Energy Expenditure

scientific article published on 17 January 2019

High-fat diet-induced hypertension and autonomic imbalance are associated with an upregulation of CART in the dorsomedial hypothalamus of mice.

artículo científico publicado en 2016

Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle

scientific article published on 28 August 2019

Hypothalamic actions of tumor necrosis factor alpha provide the thermogenic core for the wastage syndrome in cachexia

artículo científico publicado en 2009

Hypothalamic stearoyl-CoA desaturase-2 (SCD2) controls whole-body energy expenditure.

artículo científico publicado en 2015

Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2016.

artículo científico publicado en 2017

Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2018

article

Immunometabolism: molecular mechanisms, diseases, and therapies.

artículo científico publicado en 2014

Increased glyceroneogenesis in adipose tissue from rats adapted to a high-protein, carbohydrate-free diet: role of dietary fatty acids.

artículo científico publicado en 2006

Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria

scientific article published on 21 September 2018

Interscapular brown adipose tissue denervation does not promote the oxidative activity of inguinal white adipose tissue in male mice

scientific article published on 28 August 2018

Involvement of adipose tissues in the early hypolipidemic action of PPARgamma agonism in the rat

artículo científico publicado en 2006

Leukotriene-B4 modulates macrophage metabolism and fat loss in type 1 diabetic mice.

artículo científico publicado en 2019

Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids

scientific article published on 24 January 2020

Liver lipidome signature and metabolic pathways in non-alcoholic fatty liver disease induced by a high-sugar diet

artículo científico publicado en 2020

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion

artículo científico publicado en 2012

Mechanisms of the depot specificity of peroxisome proliferator-activated receptor gamma action on adipose tissue metabolism

scientific journal article

Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function

artículo científico publicado en 2012

Mild-cold water swimming does not exacerbate white adipose tissue browning and brown adipose tissue activation in mice

artículo científico publicado en 2020

Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide

scientific journal article

Omega-3 fatty acids protect from diet-induced obesity, glucose intolerance, and adipose tissue inflammation through PPARγ-dependent and PPARγ-independent actions

artículo científico publicado en 2015

PPARγ activation attenuates cold-induced upregulation of thyroid status and brown adipose tissue PGC-1α and D2

scientific journal article

PPARγ activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats.

artículo científico publicado en 2014

PPARγ is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues

article

Palmitoleate attenuates diet induced insulin resistance and hepatic inflammation independently of PPAR-α.

artículo científico publicado en 2014

Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner

artículo científico publicado en 2013

Palmitoleic acid (n-7) increases white adipocytes GLUT4 content and glucose uptake in association with AMPK activation.

artículo científico publicado en 2014

Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells

artículo científico publicado en 2020

Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status

artículo científico publicado en 2008

Polyphenols of cambuci (Campomanesia phaea (O. Berg.)) fruit ameliorate insulin resistance and hepatic steatosis in obese mice

artículo científico publicado en 2020

Preliminary report: pharmacologic 11beta-hydroxysteroid dehydrogenase type 1 inhibition increases hepatic fat oxidation in vivo and expression of related genes in rats fed an obesogenic diet

artículo científico publicado en 2009

Regulation of Adipocyte and Macrophage Functions by mTORC1 and 2 in Metabolic Diseases

scientific article published on 26 February 2020

Regulation of Metabolic Disease-Associated Inflammation by Nutrient Sensors

scientific article published on 04 July 2018

Regulation of adiposity by mTORC1.

artículo científico publicado en 2017

Regulation of brown adipose tissue recruitment, metabolism and thermogenic function by peroxisome proliferator-activated receptor γ

artículo científico publicado en 2015

Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation.

artículo científico publicado en 2009

Sympathetic Regulation of Slc2a4 Gene Expression: Participation of a Putative cAMP Responsive Element (CRE) Site in the Slc2a4 Promoter

artículo científico publicado en 2019

The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis

scientific article published on 04 October 2019

The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake

artículo científico publicado en 2009

The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis

scientific article published on 08 August 2019

Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat.

artículo científico publicado en 2008

Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice

artículo científico publicado en 2012

Turning up the heat against metabolic syndrome and non-alcoholic fatty liver disease

artículo científico publicado en 2017

mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function

artículo científico publicado en 2016

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.

artículo científico publicado en 2016

Lista de obras de William T Festuccia

11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues

A comparative perspective on lipid storage in animals

A novel peptide that improves metabolic parameters without adverse central nervous system effects.

Adaptation to a high protein, carbohydrate-free diet induces a marked reduction of fatty acid synthesis and lipogenic enzymes in rat adipose tissue that is rapidly reverted by a balanced diet.

Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis.

Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice

Basal adrenergic tone is required for maximal stimulation of rat brown adipose tissue UCP1 expression by chronic PPAR-gamma activation.

Brown adipose tissue glyceroneogenesis is activated in rats exposed to cold.

Cagaita fruit (Eugenia dysenterica DC.) and obesity: Role of polyphenols on already established obesity

Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue ⬇️

Constitutive Activation of the Nutrient Sensor mTORC1 in Myeloid Cells Induced by Tsc1 Deletion Protects Mice from Diet-Induced Obesity

Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.

Control of Brown Adipose Tissue Glucose and Lipid Metabolism by PPARγ.

Critical review of beige adipocyte thermogenic activation and contribution to whole-body energy expenditure

DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.

Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.

Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide

Depletion of Ric-8B leads to reduced mTORC2 activity

Depot-specific effects of the PPARgamma agonist rosiglitazone on adipose tissue glucose uptake and metabolism.

Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1

Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

Eicosapentaenoic Acid Reduces Adiposity, Glucose Intolerance and Increases Oxygen Consumption Independently of Uncoupling Protein 1

Exercise rescues the immune response fine-tuned impaired by peroxisome proliferator-activated receptors γ deletion in macrophages

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

Fish Oil Protects Wild Type and Uncoupling Protein 1-Deficient Mice from Obesity and Glucose Intolerance by Increasing Energy Expenditure

High-fat diet-induced hypertension and autonomic imbalance are associated with an upregulation of CART in the dorsomedial hypothalamus of mice.

Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle

Hypothalamic actions of tumor necrosis factor alpha provide the thermogenic core for the wastage syndrome in cachexia

Hypothalamic stearoyl-CoA desaturase-2 (SCD2) controls whole-body energy expenditure.

Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2016.

Immunometabolism: Molecular Mechanisms, Diseases, and Therapies 2018

Immunometabolism: molecular mechanisms, diseases, and therapies.

Increased glyceroneogenesis in adipose tissue from rats adapted to a high-protein, carbohydrate-free diet: role of dietary fatty acids.

Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria

Interscapular brown adipose tissue denervation does not promote the oxidative activity of inguinal white adipose tissue in male mice

Involvement of adipose tissues in the early hypolipidemic action of PPARgamma agonism in the rat

Leukotriene-B4 modulates macrophage metabolism and fat loss in type 1 diabetic mice.

Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids

Liver lipidome signature and metabolic pathways in non-alcoholic fatty liver disease induced by a high-sugar diet

Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion

Mechanisms of the depot specificity of peroxisome proliferator-activated receptor gamma action on adipose tissue metabolism

Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function

Mild-cold water swimming does not exacerbate white adipose tissue browning and brown adipose tissue activation in mice

Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide

Omega-3 fatty acids protect from diet-induced obesity, glucose intolerance, and adipose tissue inflammation through PPARγ-dependent and PPARγ-independent actions

PPARγ activation attenuates cold-induced upregulation of thyroid status and brown adipose tissue PGC-1α and D2

PPARγ activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats.

PPARγ is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues

Palmitoleate attenuates diet induced insulin resistance and hepatic inflammation independently of PPAR-α.

Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner

Palmitoleic acid (n-7) increases white adipocytes GLUT4 content and glucose uptake in association with AMPK activation.

Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells

Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status

Polyphenols of cambuci (Campomanesia phaea (O. Berg.)) fruit ameliorate insulin resistance and hepatic steatosis in obese mice

Preliminary report: pharmacologic 11beta-hydroxysteroid dehydrogenase type 1 inhibition increases hepatic fat oxidation in vivo and expression of related genes in rats fed an obesogenic diet

Regulation of Adipocyte and Macrophage Functions by mTORC1 and 2 in Metabolic Diseases

Regulation of Metabolic Disease-Associated Inflammation by Nutrient Sensors

Regulation of adiposity by mTORC1.

Regulation of brown adipose tissue recruitment, metabolism and thermogenic function by peroxisome proliferator-activated receptor γ

Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation.

Sympathetic Regulation of Slc2a4 Gene Expression: Participation of a Putative cAMP Responsive Element (CRE) Site in the Slc2a4 Promoter

The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis

The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake

The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis

Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat.

Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice

Turning up the heat against metabolic syndrome and non-alcoholic fatty liver disease

mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function

mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.