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Lista de obras de Pierre Desreumaux

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.

artículo científico publicado en 2013

4-Oxo-1,4-dihydropyridines as selective CB2 cannabinoid receptor ligands: structural insights into the design of a novel inverse agonist series

artículo científico publicado en 2010

4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.

artículo científico publicado en 2012

5-aminosalicylates and colorectal cancer: preventive role in chronic inflammatory bowel disease?

artículo científico publicado en 2004

5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease

artículo científico publicado en 2005

764 Results of Andante, a Randomized Clinical Study With an Anti-IL6 Antibody (PF-04236921) in Subjects With Crohn's Disease Who Are Anti-TNF Inadequate Responders

979 Modulating Peroxisome Proliferator-Activated Receptor Gamma (PPARγ): A Potential New Therapeutic Strategy for Lactose Intolerance

A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome

artículo científico publicado en 2014

AIEC colonization and pathogenicity: influence of previous antibiotic treatment and preexisting inflammation.

artículo científico publicado en 2012

Abnormalities in Mucin Gene Expression in Crohnʼs Disease

article

Acrylamide induces accelerated endothelial aging in a human cell model.

artículo científico publicado en 2015

Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease.

artículo científico publicado en 1995

Activation of PPARΓ protects against colon inflammation by inhibiting TNFA signaling pathways

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

artículo científico publicado en 1998

Adalimumab dose escalation is effective and well tolerated in Crohn's disease patients with secondary loss of response to adalimumab

artículo científico publicado en 2016

Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro

artículo científico publicado en 2007

Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice

artículo científico publicado en 2013

Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation

artículo científico publicado en 2003

Author's reply to Comment on “A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome” by Guillaume Pineton de Chambrun et al. [Digestive and Liver Disease 2015;47:119–24]

artículo científico publicado en 2015

Autologous stem cell transplantation for autoimmune diseases: recommendations from the SFGM-TC

artículo científico publicado en 2014

Bacteriophages Targeting Adherent Invasive Escherichia coli Strains as a Promising New Treatment for Crohn's Disease

artículo científico publicado en 2017

Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA

artículo científico publicado en 2002

CD28+ intraepithelial lymphocytes with long telomeres are recruited within the inflamed ileal mucosa in Crohn disease

scientific article published on 01 July 2001

CD8+ cytotoxic T cells induce relapsing colitis in normal mice.

artículo científico publicado en 2006

CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

artículo científico publicado en 2007

Cannabis : des nouvelles fonctions anti-diarrhéiques et anti-cancéreuses

artículo científico publicado en 2004

Cerebro-spinal fluid eosinophilia in shunt infections

article

Characterization of ethylcellulose: starch-based film coatings for colon targeting.

artículo científico publicado en 2009

Chronic stress stimulates organ specific cytokine expression in mice

Colon targeting with bacteria-sensitive films adapted to the disease state.

artículo científico publicado en 2009

Colonic inflammation in mice is improved by cigarette smoke through iNKT cells recruitment

artículo científico publicado en 2013

Colonization of Mice byCandida albicansIs Promoted by Chemically Induced Colitis and Augments Inflammatory Responses through Galectin‐3

article

Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.

artículo científico publicado en 2014

Crohn's disease: beyond antagonists of tumour necrosis factor

artículo científico publicado en 2008

Decreased lymphatic vessel density is associated with postoperative endoscopic recurrence in Crohn's disease

artículo científico publicado en 2013

Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

artículo científico publicado en 2015

Distinct cytokine patterns in early and chronic ileal lesions of Crohn's disease

scientific article published on 01 July 1997

Dysbiosis in inflammatory bowel disease

artículo científico publicado en 2004

Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn's Disease: Report of the TOSCA Study

artículo científico publicado en 2017

Effect of intrajejunal elemental diet perfusion on local secretion of soluble CD4 and CD8

artículo científico publicado en 1996

Effects of infliximab therapy on abdominal fat and metabolic profile in patients with Crohn's disease

artículo científico publicado en 2009

Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon

artículo científico publicado en 2017

Enhanced production of IL-8 in chronic but not in early ileal lesions of Crohn's disease (CD)

artículo científico publicado en 2000

Enteric microflora in inflammatory bowel disease patients

artículo científico publicado en 2016

Enterocolitis induced by autoimmune targeting of enteric glial cells: a possible mechanism in Crohn's disease?

artículo científico publicado en 2001

Enzymatically degraded Eurylon 6 HP-PG: ethylcellulose film coatings for colon targeting in inflammatory bowel disease patients

artículo científico publicado en 2010

Eosinophilic enteritis

artículo científico

Eosinophils in allergic reactions.

artículo científico publicado en 1996

Epithelial inflammation response induced by Shigella flexneri depends on mucin gene expression

article

Evaluation of therapeutic properties of fermented vegetables extract (OM-X®) in the model of colitis induced by Citrobacter rodentium in mice

Expression of peroxisome proliferator-activated receptor γ (PPARγ) in normal human pancreatic islet cells

artículo científico publicado en 2000

Fluorescent imaging in digestive endoscopy

artículo científico publicado en 2006

Functional polymorphisms in the regulatory regions of the VNN1 gene are associated with susceptibility to inflammatory bowel diseases

artículo científico publicado en 2013

GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

artículo científico publicado en 2012

Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia.

artículo científico publicado en 2002

Genetically related Escherichia coli strains associated with Crohn's disease.

artículo científico publicado en 2001

Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration

artículo científico publicado en 2014

Gut: An underestimated target organ for Aluminum

artículo científico publicado en 2016

Hepatic deficiency of interleukin 10 in chronic hepatitis C

artículo científico publicado en 2000

Hepatitis C virus infection down-regulates the expression of peroxisome proliferator-activated receptor alpha and carnitine palmitoyl acyl-CoA transferase 1A.

artículo científico publicado en 2005

High carriage of adherent invasive E. coli in wildlife and healthy individuals.

artículo científico publicado en 2018

How NOD2 mutations predispose to Crohn's disease?

artículo científico publicado en 2007

IL-10 hepatic deficit in hepatitis C virus (HCV) infection

IL-8 in early and chronic ileal lesions of Crohn's disease (CD)

Ige receptor affects fecal flora, bacterial translocation and intestinal inflammation

scholarly article by Sophie Nutten et al published April 2000 in Gastroenterology

Ileal or Anastomotic Location of Lesions Does Not Impact Rate of Postoperative Recurrence in Crohn's Disease Patients Classified i2 on the Rutgeerts Score.

artículo científico publicado en 2016

Immunobiology of eosinophils in allergy and inflammation.

artículo científico publicado en 1997

Immunologie du tube digestif et maladie de Crohn

scientific article published on 01 June 2004

Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma.

artículo científico publicado en 1995

Immunosupressants and MICI

artículo científico publicado en 2004

Impact of Small Bowel Exploration Using Video-Capsule Endoscopy in the Management of Acute Gastrointestinal Graft-versus-Host Disease

artículo científico publicado en 2004

Impaired contractile response of mesenteric arteries in Crohn's disease

artículo científico publicado en 2000

Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis

artículo científico publicado en 2003

Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.

artículo científico publicado en 2005

Implication of TNF-Related Apoptosis-Inducing Ligand in Inflammatory Intestinal Epithelial Lesions

artículo científico publicado en 2006

In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice

artículo científico publicado en 2013

Infectious agents and Crohn's disease

artículo científico publicado en 1999

Inflammatory alterations in mesenteric adipose tissue in Crohn's disease

artículo científico publicado en 1999

Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease

artículo científico publicado en 2001

Interleukin 5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease

artículo científico publicado en 1992

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

artículo científico publicado en 2005

Intestinal steroidogenesis

artículo científico

Intestinal steroidogenesis controls PPARγ expression in the colon and is impaired during ulcerative colitis

scientific article published on 22 July 2014

LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease

artículo científico publicado en 2007

La tomographie par cohérence optique en gastroentérologie

artículo científico publicado en 2005

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors

artículo científico publicado en 2006

Laparoscopic surgery reduces peroperative opiold requirement in Crohn's disease

Low ileal IL-10 mRNA levels predict endoscopic recurrence in patients operated on for Crohn's disease (CD)

article published in 2000

Low ileal interleukin 10 concentrations are predictive of endoscopic recurrence in patients with Crohn's disease.

artículo científico publicado en 2002

L’IL-23R, un nouveau gène de susceptibilité dans les maladies inflammatoires chroniques intestinales

article

L’endoscopie confocale

artículo científico publicado en 2005

Macrophage collections in gastrointestinal biopsies and metabolic disorders: two unusual case reports

artículo científico publicado en 2003

Manifestations digestives des allergies alimentaires chez l'adulte

artículo científico publicado en 1991

Mesenteric adipose tissue: A major source of TNFA in experimental ileitis in rats

Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's disease

artículo científico publicado en 2011

Mesenteric fat in Crohn's disease: a pathogenetic hallmark or an innocent bystander?

artículo científico publicado en 2006

Mixed Adenocarcinoid Tumor and Crohn's Disease

scientific article published on 01 June 1998

Mo1823 Highlighting of Epidemic Areas of Crohn's Disease in a Population-Based Registry Over 22 Years: Genetic or Environmental Cause?

Mo1898 Continuation or Switch to Another Anti-TNFα After Intestinal Resection in Crohn's Disease Patients Previously Exposed to Anti-TNFα?

Mo1899 Evaluation and Long-Term Benefit of Deep Remission in Crohn's Disease Patients Treated With Infliximab

Mo1900 Combination Therapy With Infliximab and Methotrexate Does Not Improve Crohn's Disease Outcome and Infliximab Tolerance Compared to Infliximab Therapy Alone

Mo1909 Adalimumab Dose Escalation Is Effective and Well Tolerated in Crohn's Disease Patients With Secondary Loss of Response to Adalimumab

Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation.

artículo científico publicado en 2005

NOD2/CARD15 et maladie de Crohn

scientific article published on 01 June 2005

NOD2: a potential target for regulating liver injury

artículo científico publicado en 2008

NODs in defence: from vulnerable antimicrobial peptides to chronic inflammation

Natural history of eosinophilic gastroenteritis

artículo científico publicado en 2011

Neoboutonia melleri var velutina Prain: in vitro and in vivo hepatoprotective effects of the aqueous stem bark extract on acute hepatitis models

artículo científico publicado en 2018

Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control

artículo científico publicado en 2009

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis

artículo científico publicado en 2011

No Evidence for an Involvement of the P38 and JNK Mitogen-Activated Protein in Inflammatory Bowel Diseases

artículo científico publicado en 2006

No evidence for involvement of the mitogen-activated protein kinase (MAPK) P38 and JNK pathways in human inflammatory bowel diseases and experimental colitis

article

Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis

artículo científico publicado en 2015

Novel polymeric film coatings for colon targeting: Drug release from coated pellets.

artículo científico publicado en 2009

Novel polymeric film coatings for colon targeting: how to adjust desired membrane properties

artículo científico publicado en 2008

O-001 A Multicenter, Double-Blind, Placebo-Controlled Phase3 Study of Ustekinumab, a Human IL-12/23P40 mAB, in Moderate-Service Crohnʼs Disease Refractory to Anti-TFNα

Obesity, visceral fat and Crohn's disease

artículo científico publicado en 2010

Oral vancomycin induces sustained deep remission in adult patients with ulcerative colitis and primary sclerosing cholangitis

Overexpression of leptin mRNA in the mesenteric adipose tissue of inflammatory bowel disease (IBD)

PPAR-gamma in ulcerative colitis: a novel target for intervention

artículo científico publicado en 2013

PPARγ

PPARγ agonists as a new class of effective treatment for ulcerative colitis

scientific article published on 01 June 2009

Parallel interleukin 5 synthesis by eosinophils in duodenal and skin lesions of a patient with dermatitis herpetiformis.

artículo científico publicado en 1995

Patients with Crohn's Disease with High Body Mass Index Present More Frequent and Rapid Loss of Response to Infliximab

artículo científico publicado en 2017

Peroxisome proliferator-activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut.

artículo científico publicado en 2017

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

artículo científico publicado en 2010

Peroxisome proliferator-activated receptor gamma in the colon: inflammation and innate antimicrobial immunity

artículo científico publicado en 2014

Pouchitis Is Associated with Mucosal Imbalance Between Interleukin-8 and Interleukin-10

scientific article published on 01 August 2000

Preclinical studies of a specific PPARγ modulator in the control of skin inflammation

artículo científico publicado en 2013

Preliminary study of urinary schistosomiasis in a village in the delta of the Senegal river basin, Senegal

artículo científico publicado en 1994

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

artículo científico publicado en 1998

Previous Exposure to Multiple Anti-TNF Is Associated with Decreased Efficiency in Preventing Postoperative Crohn's Disease Recurrence

artículo científico publicado en 2016

Probiotic Yeast Therapy for Irritable Bowel Syndrome

artículo científico publicado en 2016

Probiotics in inflammatory bowel disease: a critical review

artículo científico publicado en 2003

Pyrogenicity and cytokine-inducing properties of Streptococcus pyogenes superantigens: comparative study of streptococcal mitogenic exotoxin Z and pyrogenic exotoxin A.

artículo científico publicado en 2001

Randomised trial and open-label extension study of an anti-interleukin-6 antibody in Crohn's disease (ANDANTE I and II).

artículo científico publicado en 2017

Recent advances in the development of selective CB(2) agonists as promising anti-inflammatory agents.

artículo científico

Resistin-like molecule beta regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice

artículo científico publicado en 2008

Results of treatment with COX-2 inhibitors and lanreotide in a patient with Menetrier's hypertrophic gastropathy

artículo científico publicado en 2004

Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis

artículo científico publicado en 2017

Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases

artículo científico publicado en 2002

Régulation de l’immunité intestinale par Nod2

artículo científico publicado en 2004

Rôles de PPAR et PPAR / au cours du cancer colorectal

artículo científico publicado en 2004

Sa1846 The Expression of the Short Isoform of TSLP in the Colon Is Regulated by the Nuclear Receptor PPARγ and Is Impaired During Ulcerative Colitis

Sa1960 Crohn's Disease Patients With High Body Mass Index Present More Frequent and Rapid Loss of Response to Infliximab

article

Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis

artículo científico publicado en 2017

Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease

artículo científico publicado en 2012

Search for evidence of recurring or persistent viruses in Crohn's disease

article

Selective expansion of intraepithelial lymphocytes expressing the HLA-E–specific natural killer receptor CD94 in celiac disease

article

Similar IL-5, IL-3, and GM-CSF syntheses by eosinophils in the jejunal mucosa of patients with celiac disease and dermatitis herpetiformis.

artículo científico publicado en 1998

Specific targeting of IL-6 signalling pathway: a new way to treat IBD?

artículo científico publicado en 2000

Streptococcal pyrogenic exotoxin A (SPE A) superantigen induced production of hematopoietic cytokines, IL-12 and IL-13 by human peripheral blood mononuclear cells

artículo científico publicado en 1997

Stress-induced disruption of colonic epithelial barrier: role of interferon-gamma and myosin light chain kinase in mice

artículo científico publicado en 2003

Su1868 Dissecting the Role of RAGE in Intestinal Fibrosis

Successful induction of tolerance to infliximab in patients with Crohn's disease and prior severe infusion reactions

artículo científico publicado en 2006

Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T cells

artículo científico publicado en 2015

Switching cannabinoid response from CB2 agonists to FAAH inhibitors

artículo científico publicado en 2014

Switching invariant natural killer T (iNKT) cell response from anticancerous to anti-inflammatory effect: molecular bases.

artículo científico

Systemic Administration of Agonist Peptide Blocks the Progression of Spontaneous CD8-Mediated Autoimmune Diabetes in Transgenic Mice Without Bystander Damage

artículo científico publicado en 2000

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

artículo científico

The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ.

artículo científico publicado en 2013

The Expression of the Short Isoform of Thymic Stromal Lymphopoietin in the Colon Is Regulated by the Nuclear Receptor Peroxisome Proliferator Activated Receptor-Gamma and Is Impaired during Ulcerative Colitis

artículo científico publicado en 2017

The Presence of Adherent-Invasive Escherichia Coli (AIEC) on the Surgical Specimen is a Predictor of Severe Endoscopic Postoperative Recurrence in Ileal Crohn's Disease

The role of PPARγ-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology

artículo científico publicado en 2015

The schistosome glutathione S-transferase P28GST, a unique helminth protein, prevents intestinal inflammation in experimental colitis through a Th2-type response with mucosal eosinophils

artículo científico publicado en 2015

Toxicological consequences of experimental exposure to aluminum in human intestinal epithelial cells.

artículo científico publicado en 2016

Treatments for Crohn’s Disease–Associated Bowel Damage: A Systematic Review

artículo científico publicado en 2018

Trough Levels and Antibodies to Infliximab May Not Predict Response to Intensification of Infliximab Therapy in Patients With Inflammatory Bowel Disease

scientific article published on 29 August 2011

Trough Levels and Antibodies to Ustekinumab are not Correlated to Response to Ustekinumab Treatment in Crohn's Disease Patients

Tu1881 HLA B27 Transgenic Rat: A New Animal Model of Postsurgical Ileitis in Inflammatory Bowel Disease

Use of mouse models to evaluate the persistence, safety, and immune modulation capacities of lactic acid bacteria

artículo científico publicado en 2003

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

artículo científico publicado en 2016

Variants of NOD1 and NOD2 genes display opposite associations with familial risk of Crohn's disease and anti-saccharomyces cerevisiae antibody levels.

artículo científico publicado en 2011

Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine

artículo científico publicado en 2007

Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.

artículo científico publicado en 2013

Visceral fat and gut inflammation

artículo científico publicado en 2012

Yersinia pseudotuberculosis anti-inflammatory components reduce trinitrobenzene sulfonic acid-induced colitis in the mouse

artículo científico publicado en 2004

[Narrow band image videoendoscopy in gastroterology].

artículo científico publicado en 2005

[Nuclear receptor PPAR and hepatology: pathophysiological and therapeutical aspects].

artículo científico publicado en 2008

lnterferon-α in combination with corticosteroids improves systemic mast cell disease

artículo científico publicado en 1995

micro-Opioid receptor activation prevents acute hepatic inflammation and cell death

artículo científico publicado en 2007