Lista de obras - Johan Flygare - Dominio Público Uruguay

Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

artículo científico publicado en 2020

Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.

artículo científico publicado en 2004

Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

artículo científico publicado en 2016

Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.

artículo científico publicado en 2005

Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase

artículo científico publicado en 2020

Diamond-Blackfan anemia: erythropoiesis lost in translation

artículo científico publicado en 2006

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia

artículo científico publicado en 2012

Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

artículo científico publicado en 2016

Direct lineage reprogramming: a useful addition to the blood cell research toolbox

artículo científico publicado en 2016

Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia

artículo científico publicado en 2015

Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development

artículo científico publicado en 2007

Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells

artículo científico publicado en 2013

From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones

scientific article published on July 2010

From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

artículo científico publicado en 2011

Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.

artículo científico publicado en 2008

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

artículo científico publicado en 2015

HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal

artículo científico publicado en 2010

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits

artículo científico publicado en 2007

Identification and functional characterization of early stress erythroid progenitors using novel surface markers and in vivo tracing

scholarly article by Sofie Singbrant Soderberg published in September 2015

Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia

artículo científico publicado en 2017

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis

artículo científico publicado en 2002

Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation

artículo científico publicado en 2011

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia

artículo científico publicado en 2011

Progress towards mechanism-based treatment for Diamond-Blackfan anemia

artículo científico publicado en 2012

Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond-Blackfan anemia improves following RPS19 gene transfer

artículo científico publicado en 2003

Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.

artículo científico publicado en 2007

ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors

scientific journal article

miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.

artículo científico publicado en 2010

Lista de obras de Johan Flygare

Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.

Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.

Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase

Diamond-Blackfan anemia: erythropoiesis lost in translation

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia

Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

Direct lineage reprogramming: a useful addition to the blood cell research toolbox

Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia

Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development

Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells

From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones

From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits

Identification and functional characterization of early stress erythroid progenitors using novel surface markers and in vivo tracing

Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis

Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia

Progress towards mechanism-based treatment for Diamond-Blackfan anemia

Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond-Blackfan anemia improves following RPS19 gene transfer

Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.

ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors

miR-191 regulates mouse erythroblast enucleation by down-regulating Riok3 and Mxi1.