Filtros de búsqueda

Lista de obras de Simon F Lacey

A Phase I Study in Adults of Clofarabine Combined with High-Dose Melphalan as Reduced-Intensity Conditioning for Allogeneic Transplantation ⬇️

artículo científico publicado el 27 de julio de 2011

A cellular antidote to specifically deplete anti-CD19 chimeric antigen receptor-positive cells

artículo científico publicado en 2020

A comparative study of Merkel cell, BK and JC polyomavirus infections in renal transplant recipients and healthy subjects ⬇️

artículo científico publicado el 27 de julio de 2010

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.

artículo científico publicado en 2017

Abstract CT105: Safety and feasibility of chimeric antigen receptor modified T cells directed against mesothelin (CART-meso) in patients with mesothelin expressing cancers

artículo científico publicado en 2015

Activity of Mesothelin-specific Chimeric Antigen Receptor T cells Against Pancreatic Carcinoma Metastases in a Phase 1 Trial

artículo científico publicado en 2018

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma

artículo científico publicado en 2019

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.

artículo científico publicado en 2018

Assessment of cellular immunity to human cytomegalovirus in recipients of allogeneic stem cell transplants.

artículo científico publicado en 2004

Attenuated poxvirus expressing three immunodominant CMV antigens as a vaccine strategy for CMV infection.

artículo científico publicado en 2006

Attenuated poxviruses generate clinically relevant frequencies of CMV-specific T cells.

artículo científico publicado en 2004

Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals

artículo científico publicado en 2020

B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma

artículo científico publicado en 2019

Biomarkers in T-cell therapy clinical trials

artículo científico publicado en 2013

Biomarkers in chimeric antigen receptor T-cell therapy

scientific article published on 26 April 2018

CAR T Cell Therapy of Non-hematopoietic Malignancies: Detours on the Road to Clinical Success

article by Kristen B Long et al published 3 December 2018 in Frontiers in Immunology

CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration

artículo científico publicado en 2020

CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.

artículo científico publicado en 2000

CRISPR-engineered T cells in patients with refractory cancer

scientific article published on 07 February 2020

Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia

artículo científico publicado en 2017

Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants

artículo científico publicado en 2002

Characterization of host immunity to cytomegalovirus pp150 (UL32).

artículo científico publicado en 2005

Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice

artículo científico publicado en 2011

Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma

artículo científico publicado en 2015

Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

artículo científico publicado en 2017

Chimeric Antigen Receptor T Cells: Self-Replicating Drugs for Cancer

artículo científico publicado en 2015

Chimeric antigen receptor T cells for sustained remissions in leukemia

artículo científico publicado en 2014

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

artículo científico publicado en 2015

Clinical evaluation of safety and immunogenicity of PADRE-cytomegalovirus (CMV) and tetanus-CMV fusion peptide vaccines with or without PF03512676 adjuvant

artículo científico publicado en 2012

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

artículo científico publicado en 2015

Cross-reactive CTL recognizing two HLA-A*02-restricted epitopes within the BK virus and JC virus VP1 polypeptides are frequent in immunocompetent individuals

artículo científico publicado en 2006

Cross-reactivity of T lymphocytes recognizing a human cytotoxic T-lymphocyte epitope within BK and JC virus VP1 polypeptides.

artículo científico publicado en 2005

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

artículo científico publicado en 2016

Cytokine release syndrome associated with chimeric-antigen receptor T-cell therapy: clinicopathological insights

artículo científico publicado en 2017

Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection.

artículo científico publicado en 2005

DNA and low titer, helper-free, recombinant AAV prime-boost vaccination for cytomegalovirus induces an immune response to CMV-pp65 and CMV-IE1 in transgenic HLA A*0201 mice

artículo científico publicado en 2004

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

scientific article published on 15 July 2020

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

artículo científico publicado en 2020

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.

artículo científico publicado en 2018

Development of infectious recombinant BK virus ⬇️

artículo científico publicado el 4 de agosto de 2011

Diagnostic biomarkers to differentiate sepsis from cytokine release syndrome in critically ill children

artículo científico publicado en 2020

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

artículo científico publicado en 2018

Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication

artículo científico publicado en 2018

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

artículo científico publicado en 2016

Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer

artículo científico publicado en 2020

Endothelial Biomarkers Are Associated With Indirect Lung Injury in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome

scientific article published on 04 December 2020

Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation.

artículo científico publicado en 2018

Establishing a model system for evaluating CAR T cell therapy using dogs with spontaneous diffuse large B cell lymphoma

artículo científico publicado en 2019

Evaluating the skin in patients undergoing chimeric antigen receptor modified T-cell therapy

artículo científico publicado en 2016

Ex vivo detection of CD8 T cells specific for H-Y minor histocompatibility antigens in allogeneic hematopoietic stem cell transplant recipients

artículo científico publicado en 2014

First Trial of CRISPR-Edited T cells in Lung Cancer

artículo científico publicado en 2020

Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults

artículo científico publicado en 2007

Functional comparison of T cells recognizing cytomegalovirus pp65 and intermediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients

artículo científico publicado en 2006

Herpesvirus saimiri transformation of HIV type 1 suppressive CD8+ lymphocytes from an HIV type 1-infected asymptomatic individual

artículo científico publicado en 1998

Human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy maintain activated CD8+ T cell subsets as a strong adaptive immune response to cytomegalovirus.

artículo científico publicado en 2001

IMCT-15PILOT STUDY OF T CELLS REDIRECTED TO EGFRvIII WITH A CHIMERIC ANTIGEN RECEPTOR IN PATIENTS WITH EGFRvIII+ GLIOBLASTOMA.

artículo científico publicado en 2015

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

artículo científico publicado en 2016

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

artículo científico publicado en 2016

Immunization with Th-CTL Fusion Peptide and Cytosine-Phosphate-Guanine DNA in Transgenic HLA-A2 Mice Induces Recognition of HIV-Infected T Cells and Clears Vaccinia Virus Challenge ⬇️

artículo científico publicado el 15 de octubre de 2003

Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients

scientific article published on 15 April 2009

In vitro expansion of polyclonal T-cell subsets for adoptive immunotherapy by recombinant modified vaccinia Ankara

artículo científico

Increased programmed death-1 molecule expression in cytomegalovirus disease and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation

artículo científico publicado en 2009

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

artículo científico publicado en 2018

La Rosa C et al (J Infect Dis 2012; 205:1294–304).

artículo científico publicado en 2013

Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia

artículo científico publicado en 2020

Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma

scholarly article by David L Bajor et al published 2018 in OncoImmunology

Low frequency of BK virus in prostatic adenocarcinomas

artículo científico publicado en 2007

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy

artículo científico publicado en 2016

NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma.

artículo científico publicado en 2015

Neural Stem Cell-Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients.

artículo científico publicado en 2016

Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.

scientific article published on 28 October 2013

Neurotoxicity after CTL019 in a pediatric and young adult cohort

artículo científico publicado en 2018

Noncytolytic CD8 T cell-mediated suppression of HIV replication

artículo científico publicado en 1997

Nonviral RNA chimeric antigen receptor-modified T cells in patients with Hodgkin lymphoma

artículo científico publicado en 2018

Oblimersen and alpha-interferon in metastatic renal cancer: a phase II study of the California Cancer Consortium.

artículo científico publicado en 2007

Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia

scientific article published on 09 December 2019

PD-1 blockade modulates chimeric antigen receptor (CAR)-modified T cells: refueling the CAR.

artículo científico publicado en 2016

Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy

scientific article published on 10 May 2016

Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers

scientific article published on 30 July 2019

Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice.

artículo científico publicado en 2002

Programmed death-1 expression in liver transplant recipients as a prognostic indicator of cytomegalovirus disease.

artículo científico publicado en 2008

Programmed death-1 receptor and interleukin-10 in liver transplant recipients at high risk for late cytomegalovirus disease

artículo científico publicado en 2010

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

artículo científico publicado en 2010

Recombinant modified vaccinia virus ankara (MVA) expressing wild-type human p53 induces specific antitumor CTL expansion.

artículo científico publicado en 2011

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

scientific article published on 20 July 2018

Relative dominance of HLA-B*07 restricted CD8+ T-lymphocyte immune responses to human cytomegalovirus pp65 in persons sharing HLA-A*02 and HLA-B*07 alleles

artículo científico publicado en 2003

Relevance of peptide avidity to the T cell receptor for cytomegalovirus-specific ex vivo CD8 T cell cytotoxicity

artículo científico publicado en 2003

Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology Patients

artículo científico publicado en 2017

Risk-Adapted Preemptive Tocilizumab to Prevent Severe Cytokine Release Syndrome After CTL019 for Pediatric B-Cell Acute Lymphoblastic Leukemia: A Prospective Clinical Trial

artículo científico publicado en 2021

Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer

artículo científico publicado en 2017

Serial treatment of relapsed/refractory multiple myeloma with different BCMA-targeting therapies

scientific article published on 01 August 2019

Simultaneous reconstitution of multiple cytomegalovirus-specific CD8+ cell populations with divergent functionality in hematopoietic stem-cell transplant recipients.

artículo científico publicado en 2005

Stable HLA antibodies following sustained CD19+ cell depletion implicate a long-lived plasma cell source

scientific article published on 01 September 2020

Status of Cytomegalovirus Prevention and Treatment in 2000.

artículo científico publicado en 2000

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.

artículo científico publicado en 2017

Systemic Endothelial Activation Is Associated With Early Acute Respiratory Distress Syndrome in Children With Extrapulmonary Sepsis

artículo científico publicado en 2020

The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma.

artículo científico publicado en 2016

The CXC chemokine stromal cell-derived factor 1 is not responsible for CD8+T cell suppression of syncytia-inducing strains of HIV-1 ⬇️

artículo científico publicado el 2 de septiembre de 1997

The Safety of Bridging Radiation with Anti-BCMA CAR T-Cell Therapy for Multiple Myeloma

artículo científico publicado en 2021

The cytological features of CAR(T) cells

artículo científico publicado en 2016

The effect of single and combined activating killer immunoglobulin-like receptor genotypes on cytomegalovirus infection and immunity after hematopoietic cell transplantation

artículo científico publicado en 2009

Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of epigenome

artículo científico publicado en 2020

Treatment of leukemia antigen-loss relapses occurring after CD19-targeted immunotherapies by combination of anti-CD123 and anti-CD19 chimeric antigen receptor T cells.

artículo científico publicado en 2015

Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques.

artículo científico publicado en 2010

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda