Lista de obras - Angelo Paci - Dominio Público Uruguay

A case of melphalan sustained accumulation in an 80-year old patient.

artículo científico publicado en 2015

A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

article

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.

artículo científico publicado en 2017

Acoustic characterization of a new trisacryl contrast agent. Part I: In vitro study

artículo científico publicado en 2007

Application of an acceptance sampling plan for post-production quality control of chemotherapeutic batches in an hospital pharmacy

artículo científico publicado en 2006

Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer

artículo científico publicado en 2019

Body composition variation and impact of low skeletal muscle mass in patients with advanced medullary thyroid carcinoma treated with vandetanib: results from a placebo-controlled study

artículo científico publicado en 2013

Busulfan after HSCT in children and young adults

artículo científico publicado en 2017

Busulfan pharmacokinetics following intravenous and oral dosing regimens in children receiving high-dose myeloablative chemotherapy for high-risk neuroblastoma as part of the HR-NBL-1/SIOPEN trial.

artículo científico publicado en 2012

Busulfan-Melphalan followed by autologous stem cell transplantation in patients with high-risk neuroblastoma or Ewing sarcoma: an exposed-unexposed study evaluating the clinical impact of the order of drug administration

artículo científico publicado en 2016

Circulating oncometabolite D-2-hydroxyglutarate enantiomer is a surrogate marker of isocitrate dehydrogenase-mutated intrahepatic cholangiocarcinomas

artículo científico publicado en 2017

Colchicine is an active treatment for everolimus-induced oral ulcers

artículo científico publicado en 2017

Comparative transplacental transfer of taxanes using the human perfused cotyledon placental model

artículo científico publicado en 2012

Contribution of high-performance thin-layer chromatography to a pharmaceutical quality assurance programme in a hospital chemotherapy manufacturing unit

artículo científico publicado en 2003

Crizotinib-induced immunogenic cell death in non-small cell lung cancer

artículo científico publicado en 2019

Curcumin dietary supplements and everolimus-based cancer treatment.

artículo científico publicado en 2017

Dual-mode gradient HPLC procedure for the simultaneous determination of chloroquine and proguanil.

artículo científico publicado en 2002

Dyslipidemia causes overestimation of plasma mitotane measurements

artículo científico publicado en 2016

E.F.P.--European Fellowship for Pharmacists Promoting Clinical Pharmacy in Europe

artículo científico publicado en 2005

Early progression under mitotane and polychemotherapy does not mean failure in adrenocortical carcinoma patient.

artículo científico publicado en 2016

Efficacy and safety of gefitinib during pregnancy: case report and literature review.

artículo científico publicado en 2014

Elevated plasma ferritin and busulfan pharmacodynamics during high-dose chemotherapy regimens in children with malignant solid tumors

scientific article published on 28 March 2007

Evaluation of the pharmacokinetic profile and analgesic efficacy of oral morphine after total hip arthroplasty.

artículo científico publicado en 2006

Familial hematological malignancies: new IDH2 mutation.

artículo científico publicado en 2016

High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up

scientific article published on 02 November 2011

High-performance thin-layer chromatography with a derivatization procedure, a suitable method for the identification and the quantitation of busulfan in various pharmaceutical products.

artículo científico publicado en 2004

Human pharmacokinetic study of heated intraperitoneal oxaliplatin in increasingly hypotonic solutions after complete resection of peritoneal carcinomatosis.

artículo científico publicado en 2002

Hyperthermic pelvic perfusion with tumor necrosis factor-α for locally advanced cancers: encouraging results of a phase II study

artículo científico publicado en 2012

Identification and quantitation of antineoplastic compounds in chemotherapeutic infusion bags by use of HPTLC: application to the vinca-alkaloids.

artículo científico publicado en 2003

Individualized Pazopanib Dosing-Letter

artículo científico publicado en 2016

Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction

artículo científico publicado en 2006

Influence of the multidrug transporter P-glycoprotein on the intracellular pharmacokinetics of vandetanib.

artículo científico publicado en 2013

Insights into significance of combined inhibition of MEK and m-TOR signalling output in KRAS mutant non-small-cell lung cancer

artículo científico publicado en 2016

Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence.

artículo científico publicado en 2018

Irinotecan loaded in eluting beads: preclinical assessment in a rabbit VX2 liver tumor model

artículo científico publicado en 2012

Lipoprotein-Free Mitotane Exerts High Cytotoxic Activity in Adrenocortical Carcinoma.

artículo científico publicado en 2015

Liposomal formulation of a glycerolipidic prodrug for lymphatic delivery of didanosine via oral route

scientific article published on 03 June 2007

Liquid chromatography-mass spectrometry assay for quantitation of ifosfamide and its N-deschloroethylated metabolites in rat microsomal medium.

artículo científico publicado en 2005

Liquid chromatography-tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver.

artículo científico publicado en 2006

Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.

artículo científico publicado en 2009

Microbiological and physicochemical stability of fentanyl and sufentanil solutions for patient-controlled delivery systems.

artículo científico publicado en 2006

Microbiological and physicochemical stability of oxycodone hydrochloride solutions for patient-controlled delivery systems.

artículo científico publicado en 2010

Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations

artículo científico publicado en 2018

Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues.

artículo científico publicado en 2011

Near infrared spectroscopy and process analytical technology to master the process of busulfan paediatric capsules in a university hospital

artículo científico publicado en 2006

New dosing nomogram and population pharmacokinetic model for young and very young children receiving busulfan for hematopoietic stem cell transplantation conditioning

scientific article published on 24 July 2020

New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity

artículo científico publicado en 2008

Nilotinib versus imatinib for GIST

artículo científico publicado en 2015

Off-patent oral oncology drugs for kids (O3K FP7-project): from bedside to PUMA

artículo científico publicado en 2012

Organoids as preclinical models to improve intraperitoneal chemotherapy effectiveness for colorectal cancer patients with peritoneal metastases: Preclinical models to improve HIPEC.

artículo científico publicado en 2017

Oxazaphosphorines: new therapeutic strategies for an old class of drugs

artículo científico publicado en 2010

Parameters for Stable Water-in-Oil Lipiodol Emulsion for Liver Trans-Arterial Chemo-Eembolization

artículo científico publicado en 2017

Personalizing Busulfan-Based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee

artículo científico publicado en 2016

Pharmacokinetic Behavior and Appraisal of Intravenous Busulfan Dosing in Infants and Older Children

Pharmacokinetic interaction involving fenofibrate and everolimus

artículo científico publicado en 2014

Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors

artículo científico publicado en 2006

Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan.

artículo científico publicado en 2012

Phase I clinical trial combining imatinib mesylate and IL-2 in refractory cancer patients: IL-2 interferes with the pharmacokinetics of imatinib mesylate

artículo científico publicado en 2013

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR(+) NK cell levels correlate with disease outcome

artículo científico publicado en 2013

Phase I study of temsirolimus in combination with cetuximab in patients with advanced solid tumours.

artículo científico publicado en 2017

Phase I study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours

artículo científico publicado en 2010

Phase II study of vinorelbine and continuous low doses cyclophosphamide in children and young adults with a relapsed or refractory malignant solid tumour: good tolerance profile and efficacy in rhabdomyosarcoma--a report from the Société Française d

artículo científico publicado en 2012

Physico-chemical stability of busulfan in injectable solutions in various administration packages

artículo científico publicado en 2013

Pickering-Emulsion for Liver Trans-Arterial Chemo-Embolization with Oxaliplatin

artículo científico publicado en 2018

Poly-isoprenylated ifosfamide analogs: Preactivated antitumor agents as free formulation or nanoassemblies

artículo científico publicado en 2017

Population pharmacokinetics of busulfan in children--letter

artículo científico publicado en 2012

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

artículo científico publicado en 2014

Prevention of 5-fluorouracil-induced early severe toxicity by pre-therapeutic dihydropyrimidine dehydrogenase deficiency screening: The multiparametric approach is not convincing

artículo científico publicado en 2017

Prognostic markers of survival after combined mitotane- and platinum-based chemotherapy in metastatic adrenocortical carcinoma.

artículo científico publicado en 2010

Quality control and stability study using HPTLC: applications to cyclophosphamide in various pharmaceutical products

artículo científico publicado en 2005

Quantification of dimethyl-ifosfamide and its N-deschloropropylated metabolites in mouse plasma by liquid chromatography–tandem mass spectrometry ⬇️

artículo científico publicado el 13 de febrero de 2011

Quantitation of isocitrate dehydrogenase (IDH)-induced D and L enantiomers of 2-hydroxyglutaric acid in biological fluids by a fully validated liquid tandem mass spectrometry method, suitable for clinical applications

artículo científico publicado en 2016

Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxics

artículo científico publicado en 2014

Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies

artículo científico publicado en 2014

Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit.

artículo científico publicado en 2015

Safety and quality assurance of chemotherapeutic preparations in a hospital production unit: acceptance sampling plan and economic impact

artículo científico publicado en 2011

Safety of raltegravir-based antiretroviral therapy in HIV-infected patients receiving multi-kinase inhibitors

artículo científico publicado en 2016

Safety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study.

artículo científico publicado en 2017

Simultaneous determination of gemcitabine and gemcitabine-squalene by liquid chromatography-tandem mass spectrometry in human plasma

scientific article published on 22 August 2007

Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography-tandem mass spectrometry in mouse plasma and its application to a pharmacokinetic study

scientific article published on 20 April 2015

Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice.

artículo científico publicado en 2008

Stability of Melphalan in 0.9% Sodium Chloride Solutions Prepared in Polyvinyl Chloride Bags for Intravenous Injection

artículo científico publicado en 2015

Stabilization Improves Theranostic Properties of Lipiodol®-Based Emulsion During Liver Trans-arterial Chemo-embolization in a VX2 Rabbit Model

artículo científico publicado en 2017

Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV

article

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

artículo científico publicado en 2020

The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development

artículo científico publicado en 2016

The lack of antitumor effects of o,p'DDA excludes its role as an active metabolite of mitotane for adrenocortical carcinoma treatment

artículo científico publicado en 2014

Therapeutic Drug Monitoring of Carboplatin in High-Dose Protocol (TI-CE) for Advanced Germ Cell Tumors: Pharmacokinetic Results of a Phase II Multicenter Study

artículo científico publicado en 2017

Therapeutic drug monitoring in cancer--are we missing a trick?

artículo científico publicado en 2014

Tyrosine kinase inhibitors and pregnancy: A risk to the fetus?

artículo científico publicado en 2016

Ultrasound-induced mild hyperthermia improves the anticancer efficacy of both Taxol® and paclitaxel-loaded nanocapsules.

artículo científico publicado en 2017

Validation of a new methodology for characterizing ultrasound contrast agents (UCA)

artículo científico publicado en 2005

Variation in transplacental transfer of tyrosine kinase inhibitors in the human perfused cotyledon model

artículo científico publicado en 2015

Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.

artículo científico publicado en 2013

What sample preparation should be chosen for targeted MS monoclonal antibody quantification in human serum?

artículo científico publicado en 2018

[Dihydropyrimidine déhydrogenase (DPD) deficiency screening and securing of fluoropyrimidine-based chemotherapies: Update and recommendations of the French GPCO-Unicancer and RNPGx networks].

artículo científico publicado en 2018

Lista de obras de Angelo Paci

A case of melphalan sustained accumulation in an 80-year old patient.

A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.

Acoustic characterization of a new trisacryl contrast agent. Part I: In vitro study

Application of an acceptance sampling plan for post-production quality control of chemotherapeutic batches in an hospital pharmacy

Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer

Body composition variation and impact of low skeletal muscle mass in patients with advanced medullary thyroid carcinoma treated with vandetanib: results from a placebo-controlled study

Busulfan after HSCT in children and young adults

Busulfan pharmacokinetics following intravenous and oral dosing regimens in children receiving high-dose myeloablative chemotherapy for high-risk neuroblastoma as part of the HR-NBL-1/SIOPEN trial.

Busulfan-Melphalan followed by autologous stem cell transplantation in patients with high-risk neuroblastoma or Ewing sarcoma: an exposed-unexposed study evaluating the clinical impact of the order of drug administration

Circulating oncometabolite D-2-hydroxyglutarate enantiomer is a surrogate marker of isocitrate dehydrogenase-mutated intrahepatic cholangiocarcinomas

Colchicine is an active treatment for everolimus-induced oral ulcers

Comparative transplacental transfer of taxanes using the human perfused cotyledon placental model

Contribution of high-performance thin-layer chromatography to a pharmaceutical quality assurance programme in a hospital chemotherapy manufacturing unit

Crizotinib-induced immunogenic cell death in non-small cell lung cancer

Curcumin dietary supplements and everolimus-based cancer treatment.

Dual-mode gradient HPLC procedure for the simultaneous determination of chloroquine and proguanil.

Dyslipidemia causes overestimation of plasma mitotane measurements

E.F.P.--European Fellowship for Pharmacists Promoting Clinical Pharmacy in Europe

Early progression under mitotane and polychemotherapy does not mean failure in adrenocortical carcinoma patient.

Efficacy and safety of gefitinib during pregnancy: case report and literature review.

Elevated plasma ferritin and busulfan pharmacodynamics during high-dose chemotherapy regimens in children with malignant solid tumors

Evaluation of the pharmacokinetic profile and analgesic efficacy of oral morphine after total hip arthroplasty.

Familial hematological malignancies: new IDH2 mutation.

High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up

High-performance thin-layer chromatography with a derivatization procedure, a suitable method for the identification and the quantitation of busulfan in various pharmaceutical products.

Human pharmacokinetic study of heated intraperitoneal oxaliplatin in increasingly hypotonic solutions after complete resection of peritoneal carcinomatosis.

Hyperthermic pelvic perfusion with tumor necrosis factor-α for locally advanced cancers: encouraging results of a phase II study

Identification and quantitation of antineoplastic compounds in chemotherapeutic infusion bags by use of HPTLC: application to the vinca-alkaloids.

Individualized Pazopanib Dosing-Letter

Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction

Influence of the multidrug transporter P-glycoprotein on the intracellular pharmacokinetics of vandetanib.

Insights into significance of combined inhibition of MEK and m-TOR signalling output in KRAS mutant non-small-cell lung cancer

Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence.

Irinotecan loaded in eluting beads: preclinical assessment in a rabbit VX2 liver tumor model

Lipoprotein-Free Mitotane Exerts High Cytotoxic Activity in Adrenocortical Carcinoma.

Liposomal formulation of a glycerolipidic prodrug for lymphatic delivery of didanosine via oral route

Liquid chromatography-mass spectrometry assay for quantitation of ifosfamide and its N-deschloroethylated metabolites in rat microsomal medium.

Liquid chromatography-tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver.

Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.

Microbiological and physicochemical stability of fentanyl and sufentanil solutions for patient-controlled delivery systems.

Microbiological and physicochemical stability of oxycodone hydrochloride solutions for patient-controlled delivery systems.

Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations

Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues.

Near infrared spectroscopy and process analytical technology to master the process of busulfan paediatric capsules in a university hospital

New dosing nomogram and population pharmacokinetic model for young and very young children receiving busulfan for hematopoietic stem cell transplantation conditioning

New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity

Nilotinib versus imatinib for GIST

Off-patent oral oncology drugs for kids (O3K FP7-project): from bedside to PUMA

Organoids as preclinical models to improve intraperitoneal chemotherapy effectiveness for colorectal cancer patients with peritoneal metastases: Preclinical models to improve HIPEC.

Oxazaphosphorines: new therapeutic strategies for an old class of drugs

Parameters for Stable Water-in-Oil Lipiodol Emulsion for Liver Trans-Arterial Chemo-Eembolization

Personalizing Busulfan-Based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee

Pharmacokinetic Behavior and Appraisal of Intravenous Busulfan Dosing in Infants and Older Children

Pharmacokinetic interaction involving fenofibrate and everolimus

Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors

Pharmacology of dimethanesulfonate alkylating agents: busulfan and treosulfan.

Phase I clinical trial combining imatinib mesylate and IL-2 in refractory cancer patients: IL-2 interferes with the pharmacokinetics of imatinib mesylate

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR(+) NK cell levels correlate with disease outcome

Phase I study of temsirolimus in combination with cetuximab in patients with advanced solid tumours.

Phase I study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours

Phase II study of vinorelbine and continuous low doses cyclophosphamide in children and young adults with a relapsed or refractory malignant solid tumour: good tolerance profile and efficacy in rhabdomyosarcoma--a report from the Société Française d

Physico-chemical stability of busulfan in injectable solutions in various administration packages

Pickering-Emulsion for Liver Trans-Arterial Chemo-Embolization with Oxaliplatin

Poly-isoprenylated ifosfamide analogs: Preactivated antitumor agents as free formulation or nanoassemblies

Population pharmacokinetics of busulfan in children--letter

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

Prevention of 5-fluorouracil-induced early severe toxicity by pre-therapeutic dihydropyrimidine dehydrogenase deficiency screening: The multiparametric approach is not convincing

Prognostic markers of survival after combined mitotane- and platinum-based chemotherapy in metastatic adrenocortical carcinoma.

Quality control and stability study using HPTLC: applications to cyclophosphamide in various pharmaceutical products

Quantification of dimethyl-ifosfamide and its N-deschloropropylated metabolites in mouse plasma by liquid chromatography–tandem mass spectrometry ⬇️

Quantitation of isocitrate dehydrogenase (IDH)-induced D and L enantiomers of 2-hydroxyglutaric acid in biological fluids by a fully validated liquid tandem mass spectrometry method, suitable for clinical applications

Review of therapeutic drug monitoring of anticancer drugs part 1--cytotoxics

Review of therapeutic drug monitoring of anticancer drugs part two--targeted therapies

Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit.

Safety and quality assurance of chemotherapeutic preparations in a hospital production unit: acceptance sampling plan and economic impact

Safety of raltegravir-based antiretroviral therapy in HIV-infected patients receiving multi-kinase inhibitors

Safety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study.

Simultaneous determination of gemcitabine and gemcitabine-squalene by liquid chromatography-tandem mass spectrometry in human plasma