Lista de obras - Rodolfo Ippoliti - Dominio Público Uruguay

A Long Journey to the Cytosol

A chimeric saporin-transferrin conjugate compared to ricin toxin: role of the carrier in intracellular transport and toxicity.

artículo científico publicado en 1995

A peroxiredoxin-based proteinaceous scaffold for the growth and differentiation of neuronal cells and tumour stem cells in the absence of prodifferentiation agents

scholarly article by Annamaria Cimini et al published 8 February 2016 in Journal of Tissue Engineering and Regenerative Medicine

A ribosomal protein is specifically recognized by saporin, a plant toxin which inhibits protein synthesis

artículo científico publicado el 24 de febrero de 1992

A saporin-insulin conjugate: Synthesis and biochemical characterization

artículo científico publicado en 1996

Binding and internalization of ricin labelled with fluorescein isothiocyanate

artículo científico publicado en 1990

Biochemical and rheodynamic properties of red blood cells crosslinked with glutaraldehyde ⬇️

artículo científico publicado el 1 de octubre de 1992

Biocompatibility of composites based on chitosan, apatite, and graphene oxide for tissue applications

artículo científico publicado en 2018

Cooperative ligand binding of crosslinked hemoglobins at very high temperatures

artículo científico publicado en 1990

Covalent complex of microperoxidase with a 21-residue synthetic peptide as a maquette for low-molecular-mass redox proteins.

artículo científico publicado en 1997

Crystallization and preliminary X-ray study of saporin, a ribosome-inactivating protein fromSaponaria officinalis

artículo científico publicado en 1998

Current Status and Biomedical Applications of Ribosome-Inactivating Proteins

EV20-Sap, a novel anti-HER-3 antibody-drug conjugate, displays promising antitumor activity in melanoma.

artículo científico publicado en 2017

Effect of aromatic isothiocyanates on the functional properties of human hemoglobin. Role of the stereochemistry of the charged group.

artículo científico publicado en 1990

Endocytosis of a chimera between human pro-urokinase and the plant toxin saporin: an unusual internalization mechanism.

artículo científico publicado en 2000

Energy metabolism in glioblastoma stem cells: PPARα a metabolic adaptor to intratumoral microenvironment

artículo científico publicado en 2017

Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants

artículo científico publicado en 2009

Flavopiridol: An Old Drug With New Perspectives? Implication for Development of New Drugs

artículo científico publicado en 2016

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

artículo científico publicado en 2018

Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance

artículo científico publicado en 2016

Glutathione S-transferase tissue profiling by reporter peptide monitoring

artículo científico publicado en 2005

Human erythrocytes cross-linked with glutaraldehyde general properties and significance as a blood substitute

scientific article published on 01 October 1988

Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy

artículo científico publicado en 2012

Immunogold localisation of P-glycoprotein in supported lipid bilayers by transmission electron microscopy and atomic force microscopy

artículo científico publicado en 2001

Innovative Therapies against Human Glioblastoma Multiforme

artículo científico publicado en 2011

Intracellular dynamics of ricin followed by fluorescence microscopy on living cells reveals a rapid accumulation of the dimeric toxin in the Golgi apparatus

article

Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: possible role of 4-hydroxynonenal (4-HNE).

artículo científico publicado en 2014

Learning from the Cell Life-Cycle: A Self-adaptive Paradigm

Ligand binding and slow structural changes in chlorocruorin from Spirographis spallanzanii

scientific article published on 01 August 1993

Liposomal targeting of leukaemia HL60 cells induced by transferrin-receptor endocytosis

artículo científico publicado en 1996

Local anesthetics counteract cell proliferation and migration of human triple-negative breast cancer and melanoma cells

scientific article published on 20 September 2019

Metal-induced self-assembly of peroxiredoxin as a tool for sorting ultrasmall gold nanoparticles into one-dimensional clusters

Modulation of mitochondrial respiration by nitric oxide: investigation by single cell fluorescence microscopy

artículo científico publicado en 1999

Molecular characterization of nitrite reductase gene (aniA) and gene product in Neisseria meningitidis isolates: is aniA essential for meningococcal survival?

artículo científico publicado en 2008

Multiple strategies for O2 transport: from simplicity to complexity

artículo científico publicado en 2007

N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy.

artículo científico publicado en 2017

Neuroprotective effects of PrxI over-expression in an in vitro human Alzheimer's disease model

artículo científico publicado en 2013

Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.

artículo científico publicado en 2015

On the oxygen-linked anion-binding sites in human hemoglobin. Functional properties of human hemoglobin reacted with 4-isothiocyanatobenzenesulphonic acid and its hybrids.

artículo científico publicado en 1986

One ring (or two) to hold them all – on the structure and function of protein nanotubes.

artículo científico

Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera.

artículo científico publicado en 2016

P-glycoprotein inserted in planar lipid bilayers formed by liposomes opened on amorphous carbon and Langmuir-Blodgett monolayer.

artículo científico publicado en 2002

PDZ Domain in the Engineering and Production of a Saporin Chimeric Toxin as a Tool for targeting Cancer Cells

artículo científico publicado en 2015

PPARα Antagonist AA452 Triggers Metabolic Reprogramming and Increases Sensitivity to Radiation Therapy in Human Glioblastoma Primary Cells.

artículo científico publicado en 2016

PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms

artículo científico publicado en 2015

Physiological roles of ovotransferrin

artículo científico

Pichia pastoris as a host for secretion of toxic saporin chimeras

artículo científico publicado en 2009

Ppars In Neurodegenerative And Neuroinflammatory Pathways

artículo científico publicado en 2017

Proteolytic activity of bovine lactoferrin

artículo científico publicado en 2004

Proteolytic activity of bovine lactoferrin

scientific article published in 2004

Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase

artículo científico publicado en 2004

Ricin and Saporin: Plant Enzymes for the Research and the Clinics

article

Role of immune sera in the in-vitro phagocytosis of Bordetella pertussis strains

artículo científico publicado en 2002

Roles of PPAR transcription factors in the energetic metabolic switch occurring during adult neurogenesis.

artículo científico publicado en 2016

Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells

artículo científico publicado en 2005

Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins

artículo científico publicado en 2018

Structure and function of the plant toxin ricin, an N-glycosidase enzyme.

artículo científico publicado en 2004

Supramolecular self-assembly of graphene oxide and metal nanoparticles into stacked multilayers by means of a multitasking protein ring

artículo científico publicado en 2016

Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis

artículo científico publicado en 2013

Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems

artículo científico publicado en 2015

Targeted therapy of human glioblastoma via delivery of a toxin through a peptide directed to cell surface nucleolin.

artículo científico publicado en 2017

Targeting of saporin to Hodgkin's lymphoma cells by anti-CD30 and anti-CD25 bispecific antibodies

artículo científico publicado en 1998

The PPARβ/δ Agonist GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons: Role of PPARβ/δ in Neuronal Maturation

artículo científico publicado en 2015

The amino acid sequence and oxygen-binding properties of the single hemoglobin of the cold-adapted Antarctic teleost Gymnodraco acuticeps

article by Maurizio Tamburrini et al published January 1992 in Archives of Biochemistry and Biophysics

The amino acid sequence of a ribosome-inactivating protein from Saponaria officinalis seeds

artículo científico publicado en 1990

The effect of AZT and chloroquine on the activities of ricin and a saporin-transferrin chimeric toxin.

artículo científico publicado en 2005

The effect of monensin and chloroquine on the endocytosis and toxicity of chimeric toxins.

artículo científico publicado en 1998

The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves

artículo científico publicado en 2010

Towards a Stem Architecture Description Language for Self-Adaptive Systems

Uric Acid Amplifies Aβ Amyloid Effects Involved in the Cognitive Dysfunction/Dementia: Evidences From an Experimental Model In Vitro.

artículo científico publicado en 2016

Lista de obras de Rodolfo Ippoliti

A Long Journey to the Cytosol

A chimeric saporin-transferrin conjugate compared to ricin toxin: role of the carrier in intracellular transport and toxicity.

A peroxiredoxin-based proteinaceous scaffold for the growth and differentiation of neuronal cells and tumour stem cells in the absence of prodifferentiation agents

A ribosomal protein is specifically recognized by saporin, a plant toxin which inhibits protein synthesis

A saporin-insulin conjugate: Synthesis and biochemical characterization

Binding and internalization of ricin labelled with fluorescein isothiocyanate

Biochemical and rheodynamic properties of red blood cells crosslinked with glutaraldehyde ⬇️

Biocompatibility of composites based on chitosan, apatite, and graphene oxide for tissue applications

Cooperative ligand binding of crosslinked hemoglobins at very high temperatures

Covalent complex of microperoxidase with a 21-residue synthetic peptide as a maquette for low-molecular-mass redox proteins.

Crystallization and preliminary X-ray study of saporin, a ribosome-inactivating protein fromSaponaria officinalis

Current Status and Biomedical Applications of Ribosome-Inactivating Proteins

EV20-Sap, a novel anti-HER-3 antibody-drug conjugate, displays promising antitumor activity in melanoma.

Effect of aromatic isothiocyanates on the functional properties of human hemoglobin. Role of the stereochemistry of the charged group.

Endocytosis of a chimera between human pro-urokinase and the plant toxin saporin: an unusual internalization mechanism.

Energy metabolism in glioblastoma stem cells: PPARα a metabolic adaptor to intratumoral microenvironment

Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants

Flavopiridol: An Old Drug With New Perspectives? Implication for Development of New Drugs

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

Glioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and Radioresistance

Glutathione S-transferase tissue profiling by reporter peptide monitoring

Human erythrocytes cross-linked with glutaraldehyde general properties and significance as a blood substitute

Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy

Immunogold localisation of P-glycoprotein in supported lipid bilayers by transmission electron microscopy and atomic force microscopy

Innovative Therapies against Human Glioblastoma Multiforme

Intracellular dynamics of ricin followed by fluorescence microscopy on living cells reveals a rapid accumulation of the dimeric toxin in the Golgi apparatus

Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: possible role of 4-hydroxynonenal (4-HNE).

Learning from the Cell Life-Cycle: A Self-adaptive Paradigm

Ligand binding and slow structural changes in chlorocruorin from Spirographis spallanzanii

Liposomal targeting of leukaemia HL60 cells induced by transferrin-receptor endocytosis

Local anesthetics counteract cell proliferation and migration of human triple-negative breast cancer and melanoma cells

Metal-induced self-assembly of peroxiredoxin as a tool for sorting ultrasmall gold nanoparticles into one-dimensional clusters

Modulation of mitochondrial respiration by nitric oxide: investigation by single cell fluorescence microscopy

Molecular characterization of nitrite reductase gene (aniA) and gene product in Neisseria meningitidis isolates: is aniA essential for meningococcal survival?

Multiple strategies for O2 transport: from simplicity to complexity

N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy.

Neuroprotective effects of PrxI over-expression in an in vitro human Alzheimer's disease model

Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.

On the oxygen-linked anion-binding sites in human hemoglobin. Functional properties of human hemoglobin reacted with 4-isothiocyanatobenzenesulphonic acid and its hybrids.

One ring (or two) to hold them all – on the structure and function of protein nanotubes.

Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera.

P-glycoprotein inserted in planar lipid bilayers formed by liposomes opened on amorphous carbon and Langmuir-Blodgett monolayer.

PDZ Domain in the Engineering and Production of a Saporin Chimeric Toxin as a Tool for targeting Cancer Cells

PPARα Antagonist AA452 Triggers Metabolic Reprogramming and Increases Sensitivity to Radiation Therapy in Human Glioblastoma Primary Cells.

PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms

Physiological roles of ovotransferrin

Pichia pastoris as a host for secretion of toxic saporin chimeras

Ppars In Neurodegenerative And Neuroinflammatory Pathways

Proteolytic activity of bovine lactoferrin

Proteolytic activity of bovine lactoferrin

Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase

Ricin and Saporin: Plant Enzymes for the Research and the Clinics

Role of immune sera in the in-vitro phagocytosis of Bordetella pertussis strains

Roles of PPAR transcription factors in the energetic metabolic switch occurring during adult neurogenesis.

Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells

Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins

Structure and function of the plant toxin ricin, an N-glycosidase enzyme.

Supramolecular self-assembly of graphene oxide and metal nanoparticles into stacked multilayers by means of a multitasking protein ring

Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis

Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems

Targeted therapy of human glioblastoma via delivery of a toxin through a peptide directed to cell surface nucleolin.

Targeting of saporin to Hodgkin's lymphoma cells by anti-CD30 and anti-CD25 bispecific antibodies

The PPARβ/δ Agonist GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons: Role of PPARβ/δ in Neuronal Maturation

The amino acid sequence and oxygen-binding properties of the single hemoglobin of the cold-adapted Antarctic teleost Gymnodraco acuticeps

The amino acid sequence of a ribosome-inactivating protein from Saponaria officinalis seeds

The effect of AZT and chloroquine on the activities of ricin and a saporin-transferrin chimeric toxin.

The effect of monensin and chloroquine on the endocytosis and toxicity of chimeric toxins.

The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves

Towards a Stem Architecture Description Language for Self-Adaptive Systems

Uric Acid Amplifies Aβ Amyloid Effects Involved in the Cognitive Dysfunction/Dementia: Evidences From an Experimental Model In Vitro.