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Lista de obras de Sylvaine You

A selective CD28 antagonist and rapamycin synergise to protect against spontaneous autoimmune diabetes in NOD mice

artículo científico publicado en 2018

Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment

artículo científico publicado en 2007

Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells

artículo científico publicado en 2005

CD3 antibodies as unique tools to restore self-tolerance in established autoimmunity their mode of action and clinical application in type 1 diabetes

artículo científico publicado en 2008

Combining autologous dendritic cell therapy with CD3 antibodies promotes regulatory T cells and permanent islet allograft acceptance

artículo científico publicado en 2014

Control of Immune Response to Allogeneic Embryonic Stem Cells by CD3 Antibody-Mediated Operational Tolerance Induction

artículo científico publicado en 2015

Delayed Anti-CD3 Therapy Results in Depletion of Alloreactive T Cells and the Dominance of Foxp3+CD4+ Graft Infiltrating Cells

artículo científico publicado el 10 de junio de 2013

Detection and characterization of T cells specific for BDC2.5 T cell-stimulating peptides.

artículo científico publicado en 2003

Differential Impact of T-bet and IFNγ on Pancreatic Islet Allograft Rejection

artículo científico publicado en 2018

Differential sensitivity of regulatory and effector T cells to cell death: a prerequisite for transplant tolerance.

artículo científico

Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases

artículo científico publicado en 2003

Engagement of TLR2 Reverses the Suppressor Function of Conjunctiva CD4+CD25+Regulatory T Cells and Promotes Herpes Simplex Virus Epitope-Specific CD4+CD25−Effector T Cell Responses

artículo científico publicado el 17 de mayo de 2011

Feeding NOD mice with pig splenocytes induces transferable mechanisms that modulate cellular and humoral xenogeneic reactions against pig spleen or islet cells

artículo científico publicado en 2002

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

artículo científico publicado en 2007

Human CD3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance

scientific article published on 01 February 2011

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

artículo científico publicado en 2010

Immunoregulatory pathways controlling progression of autoimmunity in NOD mice

artículo científico publicado en 2008

In vitro xenorecognition of adult pig pancreatic islet cells by splenocytes from nonobese diabetic or non-diabetes-prone mice

artículo científico publicado en 1998

Induction of allograft tolerance by monoclonal CD3 antibodies: a matter of timing.

artículo científico publicado en 2012

Intragraft mechanisms associated with the immunosuppressive versus the tolerogenic effect of CD3 antibodies in a mouse model of islet allografts.

artículo científico publicado en 2013

Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target

artículo científico publicado en 2009

Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice

artículo científico publicado en 2017

Perifusion analysis of insulin secretion from specific pathogen-free large-white pig islets shows satisfactory functional characteristics for xenografts in humans

artículo científico publicado el 1 de junio de 1998

Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice.

artículo científico publicado en 2004

Proinsulin: a unique autoantigen triggering autoimmune diabetes.

artículo científico publicado en 2006

Regulatory mechanisms of immune tolerance in type 1 diabetes and their failures

artículo científico publicado en 2016

Revisiting the phenotypic and genetic profiling of anergic T cells mediating long-term transplant tolerance.

artículo científico publicado en 2017

Spleen cells of non-obese diabetic mice fed with pig splenocytes display modified proliferation and reduced aggressiveness in vitro against pig islet cells.

artículo científico publicado en 1998

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance

artículo científico publicado en 2016

The Induction and Maintenance of Transplant Tolerance Engages Both Regulatory and Anergic CD4+ T cells

artículo científico publicado en 2017

The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells

artículo científico publicado en 2006

Therapeutic use of a selective S1P1 receptor modulator ponesimod in autoimmune diabetes

artículo científico publicado en 2013

Tryptophan catabolism generates autoimmune-preventive regulatory T cells

artículo científico publicado en 2006