Lista de obras - John T Poirier - Dominio Público Uruguay

A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals

artículo científico publicado en 2019

Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers

scientific article published on 01 March 2019

Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.

artículo científico publicado en 2017

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

scientific article published on 01 July 2019

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

artículo científico publicado en 2016

CRISPR Libraries and Screening.

artículo científico publicado en 2017

Characterization of a full-length infectious cDNA clone and a GFP reporter derivative of the oncolytic picornavirus SVV-001 ⬇️

artículo científico publicado el 12 de septiembre de 2012

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

artículo científico publicado en 2017

Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations

scientific article published on 12 July 2019

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

artículo científico publicado en 2017

Correction: Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for use in Peptide-Prodrug Therapy.

artículo científico publicado en 2015

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

artículo científico publicado en 2015

Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens

artículo científico publicado en 2016

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

scientific article published on 08 July 2020

Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer

scientific article published on 09 July 2020

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer

artículo científico publicado en 2015

Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

artículo científico publicado en 2018

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

scientific article published on 11 September 2020

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

scientific article published on 08 October 2020

Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts

artículo científico publicado en 2022

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

artículo científico publicado en 2020

Histone Code Aberrancies in Small Cell Lung Cancer.

artículo científico publicado en 2017

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids

scientific article published on 12 July 2019

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

artículo científico publicado en 2017

Lineage reversion drives WNT independence in intestinal cancer

artículo científico publicado en 2020

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

artículo científico publicado en 2019

MYC, MAX, and small cell lung cancer.

artículo científico publicado en 2014

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

artículo científico publicado en 2019

NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

artículo científico publicado en 2018

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

scientific article published on 01 February 2020

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.

artículo científico publicado en 2016

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

artículo científico publicado en 2017

ONECUT2 is a driver of neuroendocrine prostate cancer

artículo científico publicado en 2019

P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.

artículo científico publicado en 2016

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.

artículo científico publicado en 2016

Peptide-based PET quantifies target engagement of PD-L1 therapeutics

artículo científico publicado en 2019

Phase I Clinical Study of Seneca Valley Virus (SVV-001),a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features ⬇️

artículo científico publicado el 8 de febrero de 2011

Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group

artículo científico publicado en 2014

Positron-Emission Tomographic Imaging of a Fluorine 18-Radiolabeled Poly(ADP-Ribose) Polymerase 1 Inhibitor Monitors the Therapeutic Efficacy of Talazoparib in SCLC Patient-Derived Xenografts

artículo científico publicado en 2019

ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching

artículo científico publicado en 2018

Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis

artículo científico publicado en 2016

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

artículo científico publicado en 2015

RET mutations in neuroendocrine tumors: including small-cell lung cancer

artículo científico publicado en 2014

Rapamycin rescues ABT-737 efficacy in small cell lung cancer

artículo científico publicado en 2014

Regenerative lineages and immune-mediated pruning in lung cancer metastasis

artículo científico publicado en 2020

Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

artículo científico publicado en 2021

Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

artículo científico publicado en 2013

Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy

artículo científico publicado en 2015

Small-cell lung cancer in 2016: Shining light on novel targets and therapies.

artículo científico publicado en 2016

TMEM41B is a pan-flavivirus host factor

scientific article published on 11 October 2020

Talazoparib Is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts

scientific article published on 26 June 2018

Target engagement imaging of PARP inhibitors in small-cell lung cancer.

artículo científico publicado en 2018

Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts.

artículo científico publicado en 2016

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition

artículo científico publicado en 2019

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer

artículo científico publicado en 2021

Unravelling the biology of SCLC: implications for therapy

artículo científico publicado en 2017

Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.

artículo científico publicado en 2009

Virus-Receptor Interactions and Virus Neutralization: Insights for Oncolytic Virus Development

artículo científico publicado en 2020

Virus-Receptor Interactions: Structural Insights For Oncolytic Virus Development

artículo científico publicado en 2019

Lista de obras de John T Poirier

A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals

Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers

Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.

Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer

CRISPR Libraries and Screening.

Characterization of a full-length infectious cDNA clone and a GFP reporter derivative of the oncolytic picornavirus SVV-001 ⬇️

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

Correction: Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for use in Peptide-Prodrug Therapy.

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer

Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer

Fc-mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts

HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers

Histone Code Aberrancies in Small Cell Lung Cancer.

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

Lineage reversion drives WNT independence in intestinal cancer

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer

MYC, MAX, and small cell lung cancer.

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets.

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

ONECUT2 is a driver of neuroendocrine prostate cancer

P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.

Peptide-based PET quantifies target engagement of PD-L1 therapeutics

Phase I Clinical Study of Seneca Valley Virus (SVV-001),a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features ⬇️

Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group

Positron-Emission Tomographic Imaging of a Fluorine 18-Radiolabeled Poly(ADP-Ribose) Polymerase 1 Inhibitor Monitors the Therapeutic Efficacy of Talazoparib in SCLC Patient-Derived Xenografts

ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching

Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

RET mutations in neuroendocrine tumors: including small-cell lung cancer

Rapamycin rescues ABT-737 efficacy in small cell lung cancer

Regenerative lineages and immune-mediated pruning in lung cancer metastasis

Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer

Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy

Small-cell lung cancer in 2016: Shining light on novel targets and therapies.

TMEM41B is a pan-flavivirus host factor

Talazoparib Is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts

Target engagement imaging of PARP inhibitors in small-cell lung cancer.

Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts.

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition

ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer

Unravelling the biology of SCLC: implications for therapy

Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.

Virus-Receptor Interactions and Virus Neutralization: Insights for Oncolytic Virus Development

Virus-Receptor Interactions: Structural Insights For Oncolytic Virus Development