Lista de obras - Graham M Lord - Dominio Público Uruguay

A central role for monocytes in Toll-like receptor-mediated activation of the vasculature

artículo científico publicado en 2009

A global call for action to include gender in research impact assessment

artículo científico publicado en 2016

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

artículo científico publicado en 2012

A strategy for translation

artículo científico publicado en 2007

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

artículo científico publicado en 2007

An imaging flow cytometric method for measuring cell division history and molecular symmetry during mitosis.

artículo científico publicado en 2011

Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

artículo científico publicado en 2007

Aristolochic acid nephropathy

artículo científico publicado en 2012

Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy.

artículo científico publicado en 2013

Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

artículo científico publicado en 2019

Balancing susceptibility to infection and autoimmunity: a role for leptin?

artículo científico publicado en 2002

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

artículo científico publicado en 2002

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

artículo científico publicado en 2016

Boosting translational research in the U.K.

artículo científico

CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.

artículo científico publicado en 2014

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

scientific article published on September 2009

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

artículo científico publicado en 2007

Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.

artículo científico publicado en 2013

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

artículo científico publicado en 2010

Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α

scientific article published on 30 January 2019

Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses

artículo científico publicado en 2011

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.

artículo científico publicado en 2007

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

artículo científico publicado en 2016

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

artículo científico publicado en 2010

Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples

artículo científico publicado en 2019

Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model.

artículo científico publicado en 2015

Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression

artículo científico publicado en 2020

Genetic loci influencing kidney function and chronic kidney disease

artículo científico publicado en 2010

Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.

artículo científico publicado en 2017

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

artículo científico publicado en 2013

Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis

artículo científico publicado en 2013

Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management.

artículo científico publicado en 2017

How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?

artículo científico publicado en 2014

IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

artículo científico publicado en 2016

IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER

scholarly article published 21 April 2018

Immune biomarkers: the promises and pitfalls of personalized medicine.

artículo científico publicado en 2015

Immunomodulatory role of Keratin 76 in oral and gastric cancer

scientific article published in Nature Communications

Immunotherapy

scientific article published on 01 January 1999

Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet ⬇️

artículo científico publicado el 2 de abril de 2013

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

scholarly article

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients

artículo científico publicado en 2016

Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis.

artículo científico publicado en 2000

Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery.

artículo científico publicado en 2013

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

artículo científico publicado en 2015

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

scientific article published on 02 December 2019

Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines.

artículo científico publicado en 2002

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression ⬇️

artículo científico publicado el 27 de agosto de 1998

Leptin prevents the fall in plasma osteocalcin during starvation in male mice.

artículo científico publicado en 2002

Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

artículo científico publicado en 1999

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

artículo científico publicado en 2018

Lyoplate-based multiparameter flow cytometry for the analysis of T cell subsets in human immuno-monitoring studies.

artículo científico publicado en 2011

MAGI2 Mutations Cause Congenital Nephrotic Syndrome

artículo científico publicado en 2016

Markers of achievement for assessing and monitoring gender equity in translational research organisations: a rationale and study protocol

artículo científico publicado en 2016

MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function

artículo científico publicado en 2021

Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension

artículo científico publicado en 2011

Monocytes control natural killer cell differentiation to effector phenotypes

artículo científico publicado en 2011

Multiple Cladosporium brain abscesses in a renal transplant patient: aggressive management improves outcome

scientific article published on 01 January 1997

Nephropathy caused by Chinese herbs in the UK

artículo científico publicado en 1999

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

artículo científico publicado en 2007

Plasma immunoreactive leptin concentration in end-stage renal disease.

artículo científico publicado en 1997

Preventing aristolochic acid nephropathy.

artículo científico publicado en 2015

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells

artículo científico publicado en 2020

Regulatory T-cell therapy in Crohn's disease: challenges and advances

scientific article published on 24 January 2020

Relative Resistance of Human CD4+ Memory T Cells to Suppression by CD4+CD25+ Regulatory T Cells ⬇️

artículo científico publicado el 12 de julio de 2011

Relative roles of Th1 and Th17 effector cells in allograft rejection.

artículo científico publicado en 2009

Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.

artículo científico publicado en 2001

Response to LTE 19-01163

artículo científico publicado en 2019

Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response

artículo científico publicado en 2016

Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program

artículo científico publicado en 2015

Role and species-specific expression of colon T cell homing receptor GPR15 in colitis

artículo científico publicado en 2014

Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8 effector recruitment to mucosal tissues

artículo científico publicado en 2019

Spontaneous spinal epidural haematoma: a cautionary tale.

artículo científico publicado en 1993

Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.

artículo científico publicado en 2018

Strategies for translational research in the United Kingdom

scientific article published on 01 October 2010

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

artículo científico publicado en 2016

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

artículo científico publicado en 2012

T-bet as a key regulator of mucosal immunity.

artículo científico

T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

article

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

artículo científico publicado en 2005

T-bet, a Th1 transcription factor regulates the expression of Tim-3.

artículo científico publicado en 2010

T-bet: a bridge between innate and adaptive immunity.

artículo científico publicado en 2013

The bioenergetics of the immune system.

artículo científico publicado en 2001

The challenges of stratifying patients for trials in inflammatory bowel disease.

artículo científico

The genetic determinants of renal allograft rejection

artículo científico publicado en 2018

The immune cell transcription factor T-bet: A novel metabolic regulator.

artículo científico publicado en 2013

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

artículo científico publicado en 2019

The peritoneal fluid concentration of leptin is increased in women with peritoneal but not ovarian endometriosis

artículo científico publicado en 2001

The transcription T-bet is required for optimal proinflammatory trafficking of CD4+ T cells.

artículo científico publicado en 2005

The transcription factor E4bp4/Nfil3 controls commitment to the NK lineage and directly regulates Eomes and Id2 expression.

artículo científico publicado en 2014

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

artículo científico publicado en 2012

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

artículo científico publicado en 2009

The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.

artículo científico

Transcriptional control of natural killer cell differentiation and function.

artículo científico publicado en 2011

Transcriptional regulation of the mucosal immune system mediated by T-bet.

artículo científico publicado en 2010

Translational medicine and the NIHR Biomedical Research Centre concept

artículo científico publicado en 2008

Translational mini-review series on Th17 cells: development of mouse and human T helper 17 cells.

artículo científico publicado en 2009

microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance

artículo científico publicado en 2019

Lista de obras de Graham M Lord

A central role for monocytes in Toll-like receptor-mediated activation of the vasculature

A global call for action to include gender in research impact assessment

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

A strategy for translation

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

An imaging flow cytometric method for measuring cell division history and molecular symmetry during mitosis.

Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

Aristolochic acid nephropathy

Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy.

Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

Balancing susceptibility to infection and autoimmunity: a role for leptin?

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

Boosting translational research in the U.K.

CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α

Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses

Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples

Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model.

Exhausted CD4+ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression

Genetic loci influencing kidney function and chronic kidney disease

Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis

Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management.

How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?

IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER

Immune biomarkers: the promises and pitfalls of personalized medicine.

Immunomodulatory role of Keratin 76 in oral and gastric cancer

Immunotherapy

Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet ⬇️

In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients

Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis.

Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery.

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines.

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression ⬇️

Leptin prevents the fall in plasma osteocalcin during starvation in male mice.

Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

Lyoplate-based multiparameter flow cytometry for the analysis of T cell subsets in human immuno-monitoring studies.

MAGI2 Mutations Cause Congenital Nephrotic Syndrome

Markers of achievement for assessing and monitoring gender equity in translational research organisations: a rationale and study protocol

MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function

Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension

Monocytes control natural killer cell differentiation to effector phenotypes

Multiple Cladosporium brain abscesses in a renal transplant patient: aggressive management improves outcome

Nephropathy caused by Chinese herbs in the UK

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

Plasma immunoreactive leptin concentration in end-stage renal disease.

Preventing aristolochic acid nephropathy.

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells

Regulatory T-cell therapy in Crohn's disease: challenges and advances

Relative Resistance of Human CD4+ Memory T Cells to Suppression by CD4+CD25+ Regulatory T Cells ⬇️

Relative roles of Th1 and Th17 effector cells in allograft rejection.

Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.

Response to LTE 19-01163

Retinoic Acid Signaling in B Cells Is Required for the Generation of an Effective T-Independent Immune Response

Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program

Role and species-specific expression of colon T cell homing receptor GPR15 in colitis

Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8 effector recruitment to mucosal tissues

Spontaneous spinal epidural haematoma: a cautionary tale.

Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.

Strategies for translational research in the United Kingdom

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

T-bet as a key regulator of mucosal immunity.

T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.