Lista de obras - Mats Larhed - Dominio Público Uruguay

(11)C-Labeling of a potent hydroxyethylamine BACE-1 inhibitor and evaluation in vitro and in vivo.

artículo científico publicado en 2014

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

scholarly article by Benjamin Pelcman published in August 2015

A Series of Analogues to the ATR Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

artículo científico publicado en 2019

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes.

artículo científico publicado en 2017

A new highly asymmetric chelation-controlled heck arylation

artículo científico publicado en 2003

A new regioselective Heck vinylation with enamides. Synthesis and investigation of fluorous-tagged bidentate ligands for fast separation

artículo científico publicado en 2003

A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains

artículo científico publicado en 2006

A one-pot isomerization-arylation of 2,3-epoxycyclohexanone under controlled microwave heating

artículo científico publicado en 2005

A rapid microwave protocol for Heck vinylation of aryl chlorides under air.

artículo científico publicado en 2003

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

artículo científico publicado en 2009

Achiral pyrazinone-based inhibitors of the hepatitis C virus NS3 protease and drug-resistant variants with elongated substituents directed toward the S2 pocket

artículo científico publicado en 2013

Aminocarbonylation of 4-iodo-1H-imidazoles with an amino acid amide nucleophile: synthesis of constrained H-Phe-Phe-NH2 analogues

artículo científico publicado en 2013

Aminocarbonylations employing Mo(CO)6 and a bridged two-vial system: allowing the use of nitro group substituted aryl iodides and aryl bromides

artículo científico publicado en 2012

An efficient method to perform milliliter-scale PCR utilizing highly controlled microwave thermocycling

scientific article published on 08 March 2004

Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity

artículo científico publicado en 2005

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

artículo científico publicado en 2016

Arylboronic acids as versatile coupling partners in fast microwave promoted oxidative Heck chemistry

artículo científico publicado en 2003

Aspartic protease inhibitors containing tertiary alcohol transition-state mimics

artículo científico publicado en 2014

Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density

artículo científico publicado en 2016

Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer

scientific article published on 14 September 2019

Chelation-mediated palladium(II)-catalyzed domino Heck-Mizoroki/Suzuki-Miyaura reactions using arylboronic acids: increasing scope and mechanistic understanding.

artículo científico publicado en 2011

DXR inhibition by potent mono- and disubstituted fosmidomycin analogues

artículo científico publicado en 2013

Decarboxylative palladium(II)-catalyzed synthesis of aryl amidines from aryl carboxylic acids: development and mechanistic investigation.

artículo científico publicado en 2013

Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic

artículo científico publicado en 2009

Design and synthesis of P1-P3 macrocyclic tertiary-alcohol-comprising HIV-1 protease inhibitors

artículo científico publicado en 2013

Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase

artículo científico publicado en 2011

Development of Stereocontrolled Palladium(II)-Catalyzed Domino Heck/Suzuki β,α-Diarylation Reactions with Chelating Vinyl Ethers and Arylboronic Acids

artículo científico publicado en 2012

Dimethylformamide as a carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl bromides

artículo científico publicado en 2002

Dioxygen-promoted regioselective oxidative heck arylations of electron-rich olefins with arylboronic acids

artículo científico publicado en 2004

Direct palladium(II)-catalyzed synthesis of arylamidines from aryltrifluoroborates

artículo científico publicado en 2012

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

artículo científico publicado en 2019

Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H)-pyrazinones.

artículo científico publicado en 2010

ESI-MS detection of proposed reaction intermediates in the air-promoted and ligand-modulated oxidative Heck reaction

artículo científico publicado en 2006

Easy-to-execute carbonylations: microwave synthesis of acyl sulfonamides using Mo(CO)(6) as a solid carbon monoxide source.

artículo científico publicado en 2005

Efficient palladium(II) catalysis under air. Base-free oxidative heck reactions at room temperature or with microwave heating

artículo científico publicado en 2007

Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

artículo científico publicado en 2008

Fast synthesis of aryl triflates with controlled microwave heating

artículo científico publicado en 2002

Fast, acid-free, and selective lactamization of lactones in ionic liquids

artículo científico publicado en 2008

Formamide as a combined ammonia synthon and carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl halides

artículo científico publicado en 2003

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

artículo científico publicado en 2020

Front Cover: Synthesis of 4H‐Benzo[e][1,3]oxazin‐4‐ones by a Carbonylation–Cyclization Domino Reaction of ortho‐Halophenols and Cyanamide (ChemistryOpen 5/2017).

artículo científico publicado en 2017

Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.

artículo científico publicado en 2009

HIV-1 protease inhibitors with a transition-state mimic comprising a tertiary alcohol: improved antiviral activity in cells

artículo científico publicado en 2010

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

scientific article published on 01 July 2020

High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26.

artículo científico publicado en 2017

High stereoselectivity in chelation-controlled intermolecular Heck reactions with aryl chlorides, vinyl chlorides and vinyl triflates

artículo científico publicado en 2008

High-speed heck reactions in ionic liquid with controlled microwave heating

artículo científico publicado en 2002

High-speed optimization of inhibitors of the malarial proteases plasmepsin I and II.

artículo científico publicado en 2003

High-speed synthesis of potent C2-symmetric HIV-1 protease inhibitors by in-situ aminocarbonylations

artículo científico publicado en 2005

Highly regioselective internal heck arylation of hydroxyalkyl vinyl ethers by aryl halides in water

artículo científico publicado en 2007

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

artículo científico publicado en 2016

In situ generation of carbon monoxide from solid molybdenum hexacarbonyl. A convenient and fast route to palladium-catalyzed carbonylation reactions

artículo científico publicado en 2002

In vitro and in vivo evaluation of a (18)F-labeled high affinity NOTA conjugated bombesin antagonist as a PET ligand for GRPR-targeted tumor imaging

artículo científico publicado en 2013

Increasing rates and scope of reactions: sluggish amines in microwave-heated aminocarbonylation reactions under air.

artículo científico publicado en 2003

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

artículo científico publicado en 2014

Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors ⬇️

artículo científico publicado el 26 de noviembre de 2010

Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors

artículo científico publicado en 2008

Masked 3-aminoindan-1-ones by a palladium-catalyzed three-component annulation reaction

artículo científico publicado en 2005

Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Microwave-accelerated homogeneous catalysis in organic chemistry

artículo científico publicado en 2002

Microwave-accelerated spiro-cyclizations of o-halobenzyl cyclohexenyl ethers by palladium(0) catalysis

artículo científico publicado en 2007

Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold

artículo científico publicado en 2006

Microwave-assisted high-speed PCR.

artículo científico publicado en 2003

Microwave-assisted synthesis of Weinreb and MAP aryl amides via Pd-catalyzed Heck aminocarbonylation using Mo(CO)6 or W(CO)6

artículo científico publicado en 2011

Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C.

artículo científico publicado en 2012

Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

artículo científico publicado en 2007

Microwave-enhanced aminocarbonylations in water

scientific article published on 01 July 2005

Microwave-enhanced and metal-catalyzed functionalizations of the 4-aryl-dihydropyrimidone template.

artículo científico publicado en 2005

Microwave-enhanced carbonylative generation of indanones and 3-acylaminoindanones.

artículo científico publicado en 2005

Microwave-enhanced copper-catalyzed N-arylation of free and protected amino acids in water

artículo científico publicado en 2007

Microwave-enhanced medicinal chemistry: a high-speed opportunity for convenient preparation of protease inhibitors

artículo científico publicado en 2004

Microwave-promoted aminocarbonylations of aryl chlorides using Mo(CO)(6) as a solid carbon monoxide source

artículo científico publicado en 2006

Microwave-promoted and chelation-controlled double arylations of terminal olefinic carbon of vinyl ethers

artículo científico publicado en 2004

Microwave-promoted palladium(II)-catalyzed C-P bond formation by using arylboronic acids or aryltrifluoroborates

artículo científico publicado en 2009

Molybdenum Hexacarbonyl Mediated CO Gas-Free Carbonylative Reactions

scholarly article by Luke Odell et al published 10 February 2012 in Synlett

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

scientific article published on 07 November 2020

N-Aryl Isoleucine Derivatives as Angiotensin II AT2 Receptor Ligands

artículo científico publicado en 2014

N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase

scholarly article by Benjamin Pelcman published in August 2015

Non-peptide AT2-receptor agonists

artículo científico publicado en 2010

One-pot, two-step, microwave-assisted palladium-catalyzed conversion of aryl alcohols to aryl fluorides via aryl nonaflates

artículo científico publicado en 2013

Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents.

artículo científico publicado en 2015

Optimizing solubility and permeability of a biopharmaceutics classification system (BCS) class 4 antibiotic drug using lipophilic fragments disturbing the crystal lattice.

artículo científico publicado en 2013

Oxidative Heck Reactions using Aryltrifluoroborates and Aryl N-Methyliminodiacetic Acid (MIDA) Boronates

artículo científico publicado en 2012

Palladium(0)-Catalyzed Carbonylative One-Pot Synthesis of N-Acylguanidines

artículo científico publicado en 2017

Palladium(II)-catalyzed coupling reactions with a chelating vinyl ether and arylboronic acids: a new Heck/Suzuki domino diarylation reaction.

artículo científico publicado en 2009

Palladium(II)-catalyzed desulfitative synthesis of aryl ketones from sodium arylsulfinates and nitriles: scope, limitations, and mechanistic studies

scientific article published on 31 October 2014

Protected indanones by a Heck-aldol annulation reaction

artículo científico publicado en 2002

Rapid and Efficient Conversion of (11) CO2 to (11) CO through Silacarboxylic Acids: Applications in Pd-Mediated Carbonylations.

artículo científico publicado en 2015

Rapid palladium-catalyzed synthesis of esters from aryl halides utilizing Mo(CO)(6) as a solid carbon monoxide source

artículo científico publicado en 2003

Regio- and Stereo-Selective Synthesis of Allylic Spiroethers (Spirobenzofuranes) via Intramolecular Mizoroki-Heck Reaction

artículo científico publicado en 2020

Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki-Heck Reactions.

artículo científico publicado en 2017

Regiochemical Control and Suppression of Double Bond Isomerization in the Heck Arylation of 1-(Methoxycarbonyl)-2,5-dihydropyrrole

artículo científico publicado en 1996

Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation

artículo científico publicado en 2017

Selection of optimal chelator improves the contrast of GRPR imaging using bombesin analogue RM26.

artículo científico publicado en 2016

Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction.

artículo científico publicado en 2017

Selective terminal heck arylation of vinyl ethers with aryl chlorides: a combined experimental-computational approach including synthesis of betaxolol

artículo científico publicado en 2006

Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity

artículo científico publicado en 2015

Stereoselective synthesis of 3-aminoindan-1-ones and subsequent incorporation into HIV-1 protease inhibitors

artículo científico publicado en 2006

Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

artículo científico publicado en 2018

Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

scientific article published on 02 June 2020

Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors

artículo científico publicado en 2009

Structural features determining the intestinal epithelial permeability and efflux of novel HIV-1 protease inhibitors

artículo científico publicado en 2011

Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: an attempt to improve the activity against Mycobacterium tuberculosis

artículo científico publicado en 2011

Syntheses of new tuberculosis inhibitors promoted by microwave irradiation

artículo científico publicado en 2014

Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

artículo científico publicado en 2019

Synthesis and characterization of a high-affinity NOTA-conjugated bombesin antagonist for GRPR-targeted tumor imaging.

artículo científico publicado en 2013

Synthesis and evaluation of isoleucine derived angiotensin II AT(2) receptor ligands.

artículo científico publicado en 2013

Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter

artículo científico publicado en 2017

Synthesis and labeling of a piperazine-based library of ¹¹C-labeled ligands for imaging of the vesicular acetylcholine transporter.

artículo científico publicado en 2014

Synthesis and preclinical evaluation of the CRTH2 antagonist [11C]MK-7246 as a novel PET tracer and potential surrogate marker for pancreatic beta-cell mass

artículo científico publicado en 2019

Synthesis of 11C-Labelled Ureas by Palladium(II)-Mediated Oxidative Carbonylation.

artículo científico publicado en 2017

Synthesis of 11C-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [11C]CO.

artículo científico publicado en 2016

Synthesis of 4-quinolones via a carbonylative Sonogashira cross-coupling using molybdenum hexacarbonyl as a CO source.

artículo científico publicado en 2015

Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide ⬇️

artículo científico publicado en 2017

Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation-Cyclization Domino Reaction of ortho-Halophenols and Cyanamide.

artículo científico publicado en 2017

Synthesis of Aryl Ketones by Palladium(II)‐Catalyzed Decarboxylative Addition of Benzoic Acids to Nitriles ⬇️

artículo científico publicado el 11 de octubre de 2010

Synthesis of P1'-functionalized macrocyclic transition-state mimicking HIV-1 protease inhibitors encompassing a tertiary alcohol

artículo científico publicado en 2014

Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor

artículo científico publicado en 2007

Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors

artículo científico publicado en 2011

Synthesis of styrenes by palladium(II)-catalyzed vinylation of arylboronic acids and aryltrifluoroborates by using vinyl acetate

artículo científico publicado en 2009

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

scientific article published on 02 March 2020

Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

artículo científico publicado en 2012

Temperature measurements with two different IR sensors in a continuous-flow microwave heated system

artículo científico publicado en 2013

The effect of macrocyclic chelators on the targeting properties of the 68Ga-labeled gastrin releasing peptide receptor antagonist PEG2-RM26.

artículo científico publicado en 2014

The effect of mini-PEG-based spacer length on binding and pharmacokinetic properties of a 68Ga-labeled NOTA-conjugated antagonistic analog of bombesin.

artículo científico publicado en 2014

The first ligand-modulated oxidative Heck vinylation. Efficient catalysis with molecular oxygen as palladium(0) oxidant

artículo científico publicado en 2003

Transmetallation Versus β‐Hydride Elimination: The Role of 1,4‐Benzoquinone in Chelation‐Controlled Arylation Reactions with Arylboronic Acids ⬇️

artículo científico publicado el 28 de febrero de 2012

Trastuzumab cotreatment improves survival of mice with PC-3 prostate cancer xenografts treated with the GRPR antagonist 177 Lu-DOTAGA-PEG2 -RM26.

artículo científico publicado en 2019

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

artículo científico publicado en 2012

Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic

artículo científico publicado en 2008

Ultrafast chemistry: cobalt carbonyl-mediated synthesis of diaryl ketones under microwave irradiation

scientific article published on 01 December 2003

Variations of the P2 group in HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold

artículo científico publicado en 2006

Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates

artículo científico publicado en 2015

alpha-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases

artículo científico publicado en 2009

Lista de obras de Mats Larhed

(11)C-Labeling of a potent hydroxyethylamine BACE-1 inhibitor and evaluation in vitro and in vivo.

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

A Series of Analogues to the ATR Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes.

A new highly asymmetric chelation-controlled heck arylation

A new regioselective Heck vinylation with enamides. Synthesis and investigation of fluorous-tagged bidentate ligands for fast separation

A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains

A one-pot isomerization-arylation of 2,3-epoxycyclohexanone under controlled microwave heating

A rapid microwave protocol for Heck vinylation of aryl chlorides under air.

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

Achiral pyrazinone-based inhibitors of the hepatitis C virus NS3 protease and drug-resistant variants with elongated substituents directed toward the S2 pocket

Aminocarbonylation of 4-iodo-1H-imidazoles with an amino acid amide nucleophile: synthesis of constrained H-Phe-Phe-NH2 analogues

Aminocarbonylations employing Mo(CO)6 and a bridged two-vial system: allowing the use of nitro group substituted aryl iodides and aryl bromides

An efficient method to perform milliliter-scale PCR utilizing highly controlled microwave thermocycling

Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures

Arylboronic acids as versatile coupling partners in fast microwave promoted oxidative Heck chemistry

Aspartic protease inhibitors containing tertiary alcohol transition-state mimics

Binding to and Inhibition of Insulin-Regulated Aminopeptidase by Macrocyclic Disulfides Enhances Spine Density

Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer

Chelation-mediated palladium(II)-catalyzed domino Heck-Mizoroki/Suzuki-Miyaura reactions using arylboronic acids: increasing scope and mechanistic understanding.

DXR inhibition by potent mono- and disubstituted fosmidomycin analogues

Decarboxylative palladium(II)-catalyzed synthesis of aryl amidines from aryl carboxylic acids: development and mechanistic investigation.

Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic

Design and synthesis of P1-P3 macrocyclic tertiary-alcohol-comprising HIV-1 protease inhibitors

Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Development of Stereocontrolled Palladium(II)-Catalyzed Domino Heck/Suzuki β,α-Diarylation Reactions with Chelating Vinyl Ethers and Arylboronic Acids

Dimethylformamide as a carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl bromides

Dioxygen-promoted regioselective oxidative heck arylations of electron-rich olefins with arylboronic acids

Direct palladium(II)-catalyzed synthesis of arylamidines from aryltrifluoroborates

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H)-pyrazinones.

ESI-MS detection of proposed reaction intermediates in the air-promoted and ligand-modulated oxidative Heck reaction

Easy-to-execute carbonylations: microwave synthesis of acyl sulfonamides using Mo(CO)(6) as a solid carbon monoxide source.

Efficient palladium(II) catalysis under air. Base-free oxidative heck reactions at room temperature or with microwave heating

Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery

Fast synthesis of aryl triflates with controlled microwave heating

Fast, acid-free, and selective lactamization of lactones in ionic liquids

Formamide as a combined ammonia synthon and carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl halides

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Front Cover: Synthesis of 4H‐Benzo[e][1,3]oxazin‐4‐ones by a Carbonylation–Cyclization Domino Reaction of ortho‐Halophenols and Cyanamide (ChemistryOpen 5/2017).

Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.

HIV-1 protease inhibitors with a transition-state mimic comprising a tertiary alcohol: improved antiviral activity in cells

Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

High Contrast PET Imaging of GRPR Expression in Prostate Cancer Using Cobalt-Labeled Bombesin Antagonist RM26.

High stereoselectivity in chelation-controlled intermolecular Heck reactions with aryl chlorides, vinyl chlorides and vinyl triflates

High-speed heck reactions in ionic liquid with controlled microwave heating

High-speed optimization of inhibitors of the malarial proteases plasmepsin I and II.

High-speed synthesis of potent C2-symmetric HIV-1 protease inhibitors by in-situ aminocarbonylations

Highly regioselective internal heck arylation of hydroxyalkyl vinyl ethers by aryl halides in water

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening

In situ generation of carbon monoxide from solid molybdenum hexacarbonyl. A convenient and fast route to palladium-catalyzed carbonylation reactions

In vitro and in vivo evaluation of a (18)F-labeled high affinity NOTA conjugated bombesin antagonist as a PET ligand for GRPR-targeted tumor imaging

Increasing rates and scope of reactions: sluggish amines in microwave-heated aminocarbonylation reactions under air.

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors ⬇️

Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors

Masked 3-aminoindan-1-ones by a palladium-catalyzed three-component annulation reaction

Microwave Heated Flow Synthesis of Spiro-oxindole Dihydroquinazolinone Based IRAP Inhibitors

Microwave-accelerated homogeneous catalysis in organic chemistry

Microwave-accelerated spiro-cyclizations of o-halobenzyl cyclohexenyl ethers by palladium(0) catalysis

Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold

Microwave-assisted high-speed PCR.

Microwave-assisted synthesis of Weinreb and MAP aryl amides via Pd-catalyzed Heck aminocarbonylation using Mo(CO)6 or W(CO)6

Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C.

Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase

Microwave-enhanced aminocarbonylations in water

Microwave-enhanced and metal-catalyzed functionalizations of the 4-aryl-dihydropyrimidone template.

Microwave-enhanced carbonylative generation of indanones and 3-acylaminoindanones.

Microwave-enhanced copper-catalyzed N-arylation of free and protected amino acids in water

Microwave-enhanced medicinal chemistry: a high-speed opportunity for convenient preparation of protease inhibitors

Microwave-promoted aminocarbonylations of aryl chlorides using Mo(CO)(6) as a solid carbon monoxide source

Microwave-promoted and chelation-controlled double arylations of terminal olefinic carbon of vinyl ethers

Microwave-promoted palladium(II)-catalyzed C-P bond formation by using arylboronic acids or aryltrifluoroborates

Molybdenum Hexacarbonyl Mediated CO Gas-Free Carbonylative Reactions

N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

N-Aryl Isoleucine Derivatives as Angiotensin II AT2 Receptor Ligands

N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase

Non-peptide AT2-receptor agonists