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Lista de obras de Anthony J Hannan

'Super-Enrichment' Reveals Dose-Dependent Therapeutic Effects of Environmental Stimulation in a Transgenic Mouse Model of Huntington's Disease

artículo científico publicado en 2014

A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation.

artículo científico publicado en 2013

A neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in mice

artículo científico publicado en 2015

Activity-dependent regulation of synapse and dendritic spine morphology in developing barrel cortex requires phospholipase C-beta1 signalling

artículo científico publicado en 2005

Affective dysfunction in a mouse model of Rett syndrome: Therapeutic effects of environmental stimulation and physical activity

artículo científico publicado en 2015

Altered Amygdala Excitation and CB1 Receptor Modulation of Aggressive Behavior in the Neuroligin-3 Mouse Model of Autism

artículo científico publicado en 2018

Antidepressant-Like Effect of the Norepinephrine-Dopamine Reuptake Inhibitor Bupropion in a Mouse Model of Huntington's Disease with Dopaminergic Dysfunction

artículo científico publicado en 2012

Assessing attention orienting in mice: a novel touchscreen adaptation of the Posner-style cueing task

artículo científico publicado en 2020

Australian Neuroscience Society--24th annual meeting. 27-30 January 2004, Melbourne, Australia.

artículo científico publicado en 2004

Australian Neuroscience Society--25th Annual Meeting. 30 January-2 February 2005, Perth, Australia.

artículo científico publicado en 2005

Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice.

artículo científico publicado en 2010

Behavioural state differentially engages septohippocampal cholinergic and GABAergic neurons in R6/1 Huntington's disease mice.

artículo científico publicado en 2012

Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia

artículo científico

Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis.

artículo científico publicado en 2015

Brain phylogeny, ontogeny and dysfunction: integrating evolutionary, developmental and clinical perspectives in cognitive neuroscience.

artículo científico publicado en 2007

British Neuroscience Association - 16th National Meeting. 8-11 April 2001, Harrogate, UK.

artículo científico publicado en 2001

CROC-4: a novel brain specific transcriptional activator of c-fos expressed from proliferation through to maturation of multiple neuronal cell types.

artículo científico publicado en 2000

Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine.

artículo científico publicado en 2005

Cognitive endophenotypes, gene-environment interactions and experience-dependent plasticity in animal models of schizophrenia.

artículo científico

Cortisol and depression in pre-diagnosed and early stage Huntington's disease

artículo científico publicado en 2013

Decanalization mediating gene-environment interactions in schizophrenia and other psychiatric disorders with neurodevelopmental etiology.

artículo científico publicado en 2013

Decreased expression of mGluR5 within the dorsolateral prefrontal cortex in autism and increased microglial number in mGluR5 knockout mice: Pathophysiological and neurobehavioral implications

artículo científico publicado en 2015

Decreased hippocampal cell proliferation in R6/1 Huntington's mice.

artículo científico publicado en 2004

Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice.

artículo científico publicado en 2005

Deficits in spermatogenesis but not neurogenesis are alleviated by chronic testosterone therapy in R6/1 Huntington's disease mice.

artículo científico publicado en 2012

Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice

artículo científico publicado en 2004

Depression-related behaviours displayed by female C57BL/6J mice during abstinence from chronic ethanol consumption are rescued by wheel-running.

artículo científico publicado en 2013

Diet-Induced Modification of the Sperm Epigenome Programs Metabolism and Behavior

scientific article published on 16 November 2019

Differential effects of early environmental enrichment on emotionality related behaviours in Huntington's disease transgenic mice.

artículo científico publicado en 2012

Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice.

artículo científico publicado en 2006

Differential induction and intracellular localization of SCG10 messenger RNA is associated with neuronal differentiation.

artículo científico publicado en 1996

Dissecting cause and effect in the pathogenesis of psychiatric disorders: genes, environment and behaviour.

artículo científico publicado en 2007

Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment.

artículo científico publicado en 2016

Dynamic mutations as digital genetic modulators of brain development, function and dysfunction.

artículo científico publicado en 2007

Dysregulation of synaptic proteins, dendritic spine abnormalities and pathological plasticity of synapses as experience-dependent mediators of cognitive and psychiatric symptoms in Huntington's disease.

artículo científico publicado en 2012

Editorial: Environmental Enrichment: Enhancing Neural Plasticity, Resilience, and Repair

artículo científico publicado en 2019

Effect of enhanced voluntary physical exercise on brain levels of monoamines in Huntington disease mice

artículo científico publicado en 2011

Effects of aging on the motor, cognitive and affective behaviors, neuroimmune responses and hippocampal gene expression

scientific article published on 24 January 2020

Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice.

artículo científico publicado en 2014

Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders.

artículo científico publicado en 2008

Effects of environmental manipulations in genetically targeted animal models of affective disorders.

artículo científico

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.

artículo científico publicado en 2016

Elevated paternal glucocorticoid exposure modifies memory retention in female offspring.

artículo científico publicado en 2017

Enriched environments, experience-dependent plasticity and disorders of the nervous system.

artículo científico publicado en 2006

Enviromimetics: exploring gene environment interactions to identify therapeutic targets for brain disorders.

artículo científico publicado en 2007

Environmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5

artículo científico publicado en 2015

Environmental Enrichment: A Cure for Cancer? It's All in the Mind ⬇️

artículo científico publicado el 15 de septiembre de 2010

Environmental enrichment and brain repair: harnessing the therapeutic effects of cognitive stimulation and physical activity to enhance experience-dependent plasticity

artículo científico publicado en 2014

Environmental enrichment as an experience-dependent modulator of social plasticity and cognition

artículo científico publicado en 2019

Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task

artículo científico publicado en 2017

Environmental enrichment reduces innate anxiety with no effect on depression-like behaviour in mice lacking the serotonin transporter.

artículo científico publicado en 2017

Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease

artículo científico publicado en 2010

Environmental enrichment rescues female-specific hyperactivity of the hypothalamic-pituitary-adrenal axis in a model of Huntington's disease

artículo científico publicado en 2012

Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism.

artículo científico publicado en 2004

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice

artículo científico publicado en 2002

Environmental factors as modulators of neurodegeneration: insights from gene-environment interactions in Huntington's disease.

artículo científico

Environmental modulations of the number of midbrain dopamine neurons in adult mice

artículo científico publicado en 2015

Epigenetic modifications in trinucleotide repeat diseases.

artículo científico

Epimimetics: Novel Therapeutics Targeting Epigenetic Mediators and Modulators

artículo científico publicado en 2020

Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice

artículo científico publicado en 2014

European Neuroscience--Seventh Biennial FENS Forum.

artículo científico publicado en 2010

European neuroscience - Federation of European Neuroscience Societies 5th Forum. 8-12 July 2006, Vienna, Austria.

artículo científico publicado en 2006

Evaluation of attention in APP/PS1 mice shows impulsive and compulsive behaviours

artículo científico publicado en 2019

Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety.

artículo científico publicado en 2017

Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases

scientific article published on 16 October 2019

Exploring the efficacy of constraint in animal models of stroke: meta-analysis and systematic review of the current evidence

artículo científico publicado en 2012

FENS 2000--Federation of European Neuroscience Societies. 24-28 June 2000, Brighton, UK

scientific article published on 01 October 2000

Gene-environment interactions and construct validity in preclinical models of psychiatric disorders.

artículo científico publicado en 2010

Gene-environment interactions informing therapeutic approaches to cognitive and affective disorders

artículo científico publicado en 2017

Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice.

artículo científico publicado en 2007

Gene-environment-gut interactions in Huntington's disease mice are associated with environmental modulation of the gut microbiome

artículo científico publicado en 2021

Gut dysbiosis in Huntington's disease: associations among gut microbiota, cognitive performance and clinical outcomes

artículo científico publicado en 2020

High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice

artículo científico publicado en 2014

High-Frequency Neuronal Oscillatory Abnormalities in the Phospholipase C-β1 Knockout Mouse Model of Schizophrenia

artículo científico publicado en 2019

Hippocampal neurogenesis, cognitive deficits and affective disorder in Huntington's disease

artículo científico publicado en 2012

Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.

artículo científico publicado en 2017

Hypersensitivity to sertraline in the absence of hippocampal 5-HT1AR and 5-HTT gene expression changes following paternal corticosterone treatment

scientific article published on 01 April 2018

Identifying novel interventional strategies for psychiatric disorders: integrating genomics, 'enviromics' and gene-environment interactions in valid preclinical models.

artículo científico publicado en 2014

Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.

artículo científico publicado en 2013

Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice

scientific journal article

Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice

scientific article published on 23 February 2019

International Brain Research Organization--Seventh World Congress of Neuroscience. 12-17 July 2007, Melbourne, Victoria, Australia.

artículo científico publicado en 2007

International Brain Research Organization--Sixth World Congress of Neuroscience. 10-15 July 2003, Prague, Czech Republic

artículo científico publicado el 1 de septiembre de 2003

Intracellular localization of tropomyosin mRNA and protein is associated with development of neuronal polarity.

artículo científico publicado en 1995

Investigating the relationships between hypothalamic volume and measures of circadian rhythm and habitual sleep in premanifest Huntington's disease.

artículo científico publicado en 2018

Isoform specific differences in phospholipase C beta 1 expression in the prefrontal cortex in schizophrenia and suicide

artículo científico publicado en 2017

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.

artículo científico publicado en 2014

Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain.

artículo científico publicado en 2014

Loss of the Sexually Dimorphic Neuro-Inflammatory Response in a Transgenic Mouse Model of Huntington's Disease

artículo científico publicado en 2015

Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington's disease

artículo científico publicado en 2008

Mechanisms mediating brain and cognitive reserve: experience-dependent neuroprotection and functional compensation in animal models of neurodegenerative diseases.

artículo científico publicado en 2010

Metabotropic glutamate receptors as targets for novel antipsychotic treatments.

artículo científico publicado en 2012

Microbiome profiling reveals gut dysbiosis in a transgenic mouse model of Huntington's disease

artículo científico publicado en 2018

Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease

artículo científico publicado en 2007

Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease.

artículo científico publicado en 2004

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

artículo científico publicado en 2007

Mutation of Gtf2ird1 from the Williams–Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations ⬇️

artículo científico publicado el 11 de diciembre de 2011

Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference

artículo científico publicado en 2019

N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease

artículo científico publicado en 2015

N-acetylcysteine modulates glutamatergic dysfunction and depressive behavior in Huntington's disease.

artículo científico publicado en 2016

Nature, nurture and neurobiology: Gene-environment interactions in neuropsychiatric disorders.

artículo científico publicado en 2013

Nature, nurture and neurology: gene-environment interactions in neurodegenerative disease. FEBS Anniversary Prize Lecture delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw

artículo científico publicado en 2005

Neurodegenerative diseases

artículo científico publicado en 2001

Neuroendocrine and neurotrophic signaling in Huntington's disease: Implications for pathogenic mechanisms and treatment strategies

artículo científico publicado en 2016

Neuroscience--Fifth IBRO World Congress. 11-15 July 1999, Jerusalem, Israel.

artículo científico publicado en 1999

Noninvasive strategies to optimise brain plasticity: from basic research to clinical perspectives.

scientific article published on 30 December 2013

Novel approaches to alcohol rehabilitation: Modification of stress-responsive brain regions through environmental enrichment.

artículo científico publicado en 2018

Novel ethological endophenotypes in a transgenic mouse model of Huntington's disease

artículo científico publicado en 2014

Novel therapeutic targets for Huntington's disease.

artículo científico publicado en 2005

Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients

artículo científico publicado en 2007

PLC-beta1 knockout mice as a model of disrupted cortical development and plasticity: behavioral endophenotypes and dysregulation of RGS4 gene expression

scientific journal article

Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene

scientific article published on 15 July 2019

Paternal environmental enrichment transgenerationally alters affective behavioral and neuroendocrine phenotypes

artículo científico publicado en 2017

Phospholipase C beta 1 expression in the dorsolateral prefrontal cortex from patients with schizophrenia at different stages of illness.

artículo científico publicado en 2010

Phospholipase C-beta1 expression correlates with neuronal differentiation and synaptic plasticity in rat somatosensory cortex.

artículo científico publicado en 1998

Plastic brains and gastrointestinal strains: The microbiota–gut–brain axis as a modulator of cellular plasticity and cognitive function (commentary on Darch et al., 2021)

artículo científico publicado en 2021

Positive environmental modification of depressive phenotype and abnormal hypothalamic-pituitary-adrenal axis activity in female C57BL/6J mice during abstinence from chronic ethanol consumption

artículo científico publicado en 2013

Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.

artículo científico publicado en 2015

Regulator of G-protein signalling 4 expression is not altered in the prefrontal cortex in schizophrenia

artículo científico publicado en 2008

Regulators of adult neurogenesis in the healthy and diseased brain

artículo científico publicado en 2007

Role of muscarinic receptors in the activity of N-desmethylclozapine: reversal of hyperactivity in the phospholipase C knockout mouse.

artículo científico publicado en 2008

Search strategy selection in the Morris water maze indicates allocentric map formation during learning that underpins spatial memory formation.

artículo científico publicado en 2016

Sex-specific behavioural effects of environmental enrichment in a transgenic mouse model of amyotrophic lateral sclerosis.

artículo científico publicado en 2008

Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling

artículo científico publicado en 2014

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease

artículo científico publicado en 2014

Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment

artículo científico publicado en 2020

Short-Term Environmental Stimulation Spatiotemporally Modulates Specific Serotonin Receptor Gene Expression and Behavioral Pharmacology in a Sexually Dimorphic Manner in Huntington's Disease Transgenic Mice

article

Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression

scientific article published on 01 October 2019

Short-term memory acquisition in female Huntington's disease mice is vulnerable to acute stress.

artículo científico publicado en 2013

Simple sequence repeats: genetic modulators of brain function and behavior.

artículo científico publicado en 2008

Social Isolation Alters Social and Mating Behavior in the R451C Neuroligin Mouse Model of Autism.

artículo científico publicado en 2017

Society for neuroscience-33rd annual meeting.

artículo científico publicado en 2004

Stressing the Seminal Role of Paternal Experience in Transgenerational 'Epigenopathy' Affecting Offspring Health and Disease Susceptibility

scientific article published on 21 July 2018

Structural compartments within neurons: developmentally regulated organization of microfilament isoform mRNA and protein.

artículo científico publicado en 1998

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease.

artículo científico publicado en 2017

Synaptopathy, circuitopathy and the computational biology of Huntington's disease.

artículo científico publicado en 2018

TRPing up the genome: Tandem repeat polymorphisms as dynamic sources of genetic variability in health and disease.

artículo científico publicado en 2010

Tandem Repeats and Repeatomes: Delving Deeper into the 'Dark Matter' of Genomes.

artículo científico publicado en 2018

Tandem repeats mediating genetic plasticity in health and disease

artículo científico publicado en 2018

The Role of Epigenetic Change in Autism Spectrum Disorders.

artículo científico publicado en 2015

The effects of short-term and long-term environmental enrichment on locomotion, mood-like behavior, cognition and hippocampal gene expression

artículo científico publicado en 2019

The influence of the HPG axis on stress response and depressive-like behaviour in a transgenic mouse model of Huntington's disease.

artículo científico publicado en 2014

The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice

artículo científico publicado en 2011

The relationship between cortisol and verbal memory in the early stages of Huntington's disease

artículo científico publicado en 2012

Therapeutic Effects of Anthocyanins and Environmental Enrichment in R6/1 Huntington's Disease Mice

artículo científico publicado en 2016

Thinking with your stomach? Gut feelings on microbiome modulation of brain structure and function (Commentary on Luczynski et al.).

artículo científico publicado en 2016

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait.

artículo científico publicado en 2013

Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5

artículo científico publicado en 2018

Towards a therapy for Huntington's disease (Commentary on Giampà et al.).

artículo científico publicado en 2009

Towards environmental construct validity in animal models of CNS disorders: optimizing translation of preclinical studies.

artículo científico

Toxoplasmosis: A pathway to neuropsychiatric disorders

scientific article published on 23 November 2018

Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways

artículo científico publicado en 2017

Transgenerational epigenetic impacts of parental infection on offspring health and disease susceptibility

artículo científico publicado en 2022

Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders.

artículo científico publicado en 2018

Transgenerational paternal transmission of acquired traits: Stress-induced modification of the sperm regulatory transcriptome and offspring phenotypes

artículo científico publicado en 2017

Transgenic Mouse Models as Tools for Understanding How Increased Cognitive and Physical Stimulation Can Improve Cognition in Alzheimer's Disease

artículo científico publicado en 2018

Translating preclinical environmental enrichment studies for the treatment of autism and other brain disorders: comment on Woo and Leon (2013).

artículo científico publicado en 2013

Translational Assays for Assessment of Cognition in Rodent Models of Alzheimer's Disease and Dementia.

artículo científico publicado en 2016

Treatment of depressive-like behaviour in Huntington's disease mice by chronic sertraline and exercise.

artículo científico publicado en 2012

Trinucleotide-repeat expansion diseases

artículo científico publicado en 1997

Trinucleotide-repeat expansions and neurodegenerative diseases

artículo científico publicado en 1995

Vascular endothelial growth factor and brain-derived neurotrophic factor in quetiapine treated first-episode psychosis

artículo científico publicado en 2014

What's wrong with my mouse cage? Methodological considerations for modeling lifestyle factors and gene-environment interactions in mice

artículo científico

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.

artículo científico publicado en 2010

Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease

artículo científico publicado en 2008

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