Lista de obras - Takashi Takahashi - Dominio Público Uruguay

A 25-signal proteomic signature and outcome for patients with resected non-small-cell lung cancer.

artículo científico publicado en 2007

A chemical mismatch cleavage method useful for the detection of point mutations in the p53 gene in lung cancer

artículo científico publicado en 1990

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

artículo científico publicado en 2002

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

artículo científico publicado en 2005

A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer.

artículo científico publicado en 2006

ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.

artículo científico publicado en 2005

Aberrant DNA replication in cancer.

artículo científico

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

artículo científico publicado en 2002

Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.

artículo científico publicado en 2003

Altered regulation of c-jun and its involvement in anchorage-independent growth of human lung cancers.

artículo científico publicado en 2006

Analysis of beta-tubulin gene alteration in human lung cancer cell lines.

artículo científico publicado en 2003

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

artículo científico publicado en 2007

Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones.

artículo científico publicado en 2007

BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.

artículo científico publicado en 2013

Blood-borne miRNA profile-based diagnostic classifier for lung adenocarcinoma

artículo científico publicado en 2016

Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production

artículo científico publicado en 2013

Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway.

artículo científico publicado en 2003

Characterization of high-grade neuroendocrine tumors of the lung in relation to menin mutations.

artículo científico publicado en 2000

Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: an international validation study

artículo científico publicado en 2010

Cloning and characterization of the alternative promoter regions of the human LIMK2 gene responsible for alternative transcripts with tissue-specific expression

artículo científico publicado en 1999

Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma

artículo científico publicado en 2014

Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers

artículo científico publicado en 2009

Decreased expression of 14-3-3sigma in neuroendocrine tumors is independent of origin and malignant potential.

artículo científico publicado en 2002

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer.

artículo científico publicado en 2008

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation ⬇️

artículo científico publicado el 1 de agosto de 1992

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

artículo científico publicado en 2011

Differential effect of p53 on the promoters of mouse DNA polymerase beta gene and proliferating-cell-nuclear-antigen gene

artículo científico publicado en 1994

Differential expression of the c-kit proto-oncogene in germ cell tumours.

artículo científico publicado en 1995

Differential inactivation of caspase-8 in lung cancers.

artículo científico publicado en 2002

Disproportionate representation ofKRAS gene mutation in atypical adenomatous hyperplasia, but even distribution ofEGFR gene mutation from preinvasive to invasive adenocarcinomas

article

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction

artículo científico publicado en 2019

ESDN is a marker of vascular remodeling and regulator of cell proliferation in graft arteriosclerosis.

artículo científico publicado en 2007

Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis

artículo científico publicado en 2010

Epidermal growth factor receptor gene amplification is acquired in association with tumor progression of EGFR-mutated lung cancer.

artículo científico publicado en 2008

Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation.

artículo científico publicado en 2014

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

artículo científico

Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.

artículo científico publicado en 2007

Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer

artículo científico publicado en 2012

Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model

artículo científico publicado en 2017

Frondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis

artículo científico publicado en 2013

Gene expression dose-response changes in microarrays after exposure of human peripheral lung epithelial cells to nickel(II).

artículo científico publicado en 2003

Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.

artículo científico publicado en 2002

Genomic structure of the human PLCD1 (phospholipase C delta 1) locus on 3p22-->p21.3

artículo científico publicado en 1997

Growth stimulation of human pulmonary adenocarcinoma cells and small airway epithelial cells by beta-carotene via activation of cAMP, PKA, CREB and ERK1/2.

artículo científico publicado en 2006

Helicobacter pylori infection is associated with favorable outcome in advanced gastric cancer patients treated with S-1 adjuvant chemotherapy

artículo científico publicado en 2018

Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia

artículo científico publicado en 1992

Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma.

artículo científico publicado en 2010

Identification of MGB1 as a marker in the differential diagnosis of lung tumors in patients with a history of breast cancer by analysis of publicly available SAGE data

artículo científico publicado en 2004

Identification of decatenation G2 checkpoint impairment independently of DNA damage G2 checkpoint in human lung cancer cell lines.

artículo científico publicado en 2004

Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster

artículo científico publicado en 2008

Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer

artículo científico publicado en 1990

In vitro effects of a recombinant toxin, mSCF-PE40, targeting c-kit receptors ectopically expressed in small cell lung cancers

artículo científico publicado en 1997

Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.

artículo científico publicado en 2017

Inhibition of HSP90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma

artículo científico publicado en 2020

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells.

artículo científico publicado en 2010

Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1

artículo científico publicado en 2013

Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins

artículo científico publicado en 1992

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

artículo científico publicado en 2011

K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.

artículo científico

LKB1 gene mutations in Japanese lung cancer patients.

artículo científico publicado en 2007

Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1

artículo científico publicado en 2007

Loss of heterozygosity (LOH) at 17q and 14q in human lung cancers.

artículo científico publicado en 1998

Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features.

artículo científico publicado en 2014

Lung cancer: an ever increasing store of in-depth basic knowledge and the beginning of its clinical application

artículo científico publicado en 2002

MYBPH inhibits NM IIA assembly via direct interaction with NMHC IIA and reduces cell motility

artículo científico publicado en 2012

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

artículo científico publicado en 2012

Maspin expression in normal lung and non-small-cell lung cancers: cellular property-associated expression under the control of promoter DNA methylation.

artículo científico publicado en 2004

Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.

artículo científico publicado en 2010

Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis

artículo científico publicado en 2013

MicroRNAs in biological processes and carcinogenesis.

artículo científico publicado en 2006

Molecular cloning of human TAK1 and its mutational analysis in human lung cancer

scientific journal article

Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.

artículo científico publicado en 2001

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

artículo científico publicado en 2004

Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence

artículo científico publicado en 2005

Mutations of the p53 tumor suppressor gene as clonal marker for multiple primary lung cancers

article

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

artículo científico publicado en 2012

Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer.

artículo científico publicado en 2009

Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells

scientific article published on 01 July 2007

Phenotypic composition of salivary gland tumors: an application of principal [corrected] component analysis to tissue microarray data.

artículo científico publicado en 2004

Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction.

artículo científico publicado en 2004

Protective function of p27(KIP1) against apoptosis in small cell lung cancer cells in unfavorable microenvironments

artículo científico publicado en 2001

Quantitative proteomic profiling identifies DPYSL3 as pancreatic ductal adenocarcinoma-associated molecule that regulates cell adhesion and migration by stabilization of focal adhesion complex

artículo científico publicado en 2013

ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1

artículo científico publicado en 2016

ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma

artículo científico publicado en 2019

Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma

artículo científico

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

artículo científico publicado en 2005

Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients.

artículo científico publicado en 2004

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

artículo científico publicado en 2004

Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer.

artículo científico publicado en 2010

Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis.

artículo científico publicado en 2009

Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses.

artículo científico publicado en 2009

Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells

artículo científico publicado en 2009

Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer.

artículo científico publicado en 2008

SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers

artículo científico publicado en 2013

Serum glutathione S-transferase-pi level as a tumor marker for non-small cell lung cancer. Potential predictive value in chemotherapeutic response.

artículo científico publicado en 1994

Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo.

artículo científico publicado en 2002

TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

artículo científico publicado en 2017

Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.

artículo científico publicado en 2015

Temperature-sensitive mutants of p53 associated with human carcinoma of the lung

scientific article published on 01 January 1992

Tetraspanin CD151 regulates transforming growth factor beta signaling: implication in tumor metastasis.

artículo científico publicado en 2010

The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells

artículo científico publicado en 2012

The Epstein-Barr virus latent membrane protein 1 and transforming growth factor--β1 synergistically induce epithelial--mesenchymal transition in lung epithelial cells.

artículo científico publicado en 2010

Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo

artículo científico publicado en 2012

Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells

artículo científico publicado en 2017

Topographical distributions of allelic loss in individual non-small-cell lung cancers

artículo científico publicado en 2000

Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis.

artículo científico publicado en 2012

Tumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages

artículo científico publicado en 2014

Vascular Endothelial Growth Factor Receptor 3 Is Involved in Tumor Angiogenesis and Growth

article

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

artículo científico publicado en 2005

hDREF regulates cell proliferation and expression of ribosomal protein genes

artículo científico publicado en 2007

let-7 and miR-17-92: small-sized major players in lung cancer development

artículo científico publicado en 2011

let-7 regulates Dicer expression and constitutes a negative feedback loop

artículo científico publicado en 2008

miR-342-3p regulates MYC transcriptional activity via direct repression of E2F1 in human lung cancer.

artículo científico publicado en 2015

miR-375 is activated by ASH1 and inhibits YAP1 in a lineage-dependent manner in lung cancer.

artículo científico publicado en 2011

Lista de obras de Takashi Takahashi

A 25-signal proteomic signature and outcome for patients with resected non-small-cell lung cancer.

A chemical mismatch cleavage method useful for the detection of point mutations in the p53 gene in lung cancer

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer.

ASH1 gene is a specific therapeutic target for lung cancers with neuroendocrine features.

Aberrant DNA replication in cancer.

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.

Altered regulation of c-jun and its involvement in anchorage-independent growth of human lung cancers.

Analysis of beta-tubulin gene alteration in human lung cancer cell lines.

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

Aryl radical involvement in amiodarone-induced pulmonary toxicity: investigation of protection by spin-trapping nitrones.

BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.

Blood-borne miRNA profile-based diagnostic classifier for lung adenocarcinoma

Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production

Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway.

Characterization of high-grade neuroendocrine tumors of the lung in relation to menin mutations.

Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: an international validation study

Cloning and characterization of the alternative promoter regions of the human LIMK2 gene responsible for alternative transcripts with tissue-specific expression

Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma

Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers

Decreased expression of 14-3-3sigma in neuroendocrine tumors is independent of origin and malignant potential.

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer.

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation ⬇️

Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis

Differential effect of p53 on the promoters of mouse DNA polymerase beta gene and proliferating-cell-nuclear-antigen gene

Differential expression of the c-kit proto-oncogene in germ cell tumours.

Differential inactivation of caspase-8 in lung cancers.

Disproportionate representation ofKRAS gene mutation in atypical adenomatous hyperplasia, but even distribution ofEGFR gene mutation from preinvasive to invasive adenocarcinomas

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction

ESDN is a marker of vascular remodeling and regulator of cell proliferation in graft arteriosclerosis.

Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis

Epidermal growth factor receptor gene amplification is acquired in association with tumor progression of EGFR-mutated lung cancer.

Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation.

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.

Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer

Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model

Frondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis

Gene expression dose-response changes in microarrays after exposure of human peripheral lung epithelial cells to nickel(II).

Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.

Genomic structure of the human PLCD1 (phospholipase C delta 1) locus on 3p22-->p21.3

Growth stimulation of human pulmonary adenocarcinoma cells and small airway epithelial cells by beta-carotene via activation of cAMP, PKA, CREB and ERK1/2.

Helicobacter pylori infection is associated with favorable outcome in advanced gastric cancer patients treated with S-1 adjuvant chemotherapy

Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia

Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma.

Identification of MGB1 as a marker in the differential diagnosis of lung tumors in patients with a history of breast cancer by analysis of publicly available SAGE data

Identification of decatenation G2 checkpoint impairment independently of DNA damage G2 checkpoint in human lung cancer cell lines.

Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster

Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer

In vitro effects of a recombinant toxin, mSCF-PE40, targeting c-kit receptors ectopically expressed in small cell lung cancers

Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.

Inhibition of HSP90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells.

Inhibitory Effects of Salinomycin on Cell Survival, Colony Growth, Migration, and Invasion of Human Non-Small Cell Lung Cancer A549 and LNM35: Involvement of NAG-1

Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.

LKB1 gene mutations in Japanese lung cancer patients.

Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1

Loss of heterozygosity (LOH) at 17q and 14q in human lung cancers.

Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features.

Lung cancer: an ever increasing store of in-depth basic knowledge and the beginning of its clinical application

MYBPH inhibits NM IIA assembly via direct interaction with NMHC IIA and reduces cell motility

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

Maspin expression in normal lung and non-small-cell lung cancers: cellular property-associated expression under the control of promoter DNA methylation.

Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.

Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis

MicroRNAs in biological processes and carcinogenesis.

Molecular cloning of human TAK1 and its mutational analysis in human lung cancer

Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence

Mutations of the p53 tumor suppressor gene as clonal marker for multiple primary lung cancers

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer.

Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells

Phenotypic composition of salivary gland tumors: an application of principal [corrected] component analysis to tissue microarray data.