Lista de obras - Giuseppe Pignataro - Dominio Público Uruguay

A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage.

artículo científico publicado en 2008

Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases.

artículo científico publicado en 2007

Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia

artículo científico publicado en 2018

Alcohol increases spontaneous BOLD signal fluctuations in the visual network

artículo científico publicado en 2010

Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats

artículo científico publicado en 2019

Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia.

artículo científico publicado en 2007

Corrigendum to "NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia" [Neurobiol. Dis. 45 (2012) 616-623].

artículo científico publicado en 2016

Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains

artículo científico publicado en 2009

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration

article

Does Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention?

artículo científico publicado en 2013

Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism.

artículo científico publicado en 2007

Editorial: Mechanisms of Innate Neuroprotection.

artículo científico publicado en 2016

Effects of bone marrow mesenchymal stem cells (BM-MSCs) on rat pial microvascular remodeling after transient middle cerebral artery occlusion

artículo científico publicado en 2015

Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype.

artículo científico publicado en 2015

Genetically modified mice as a strategy to unravel the role played by the Na(+)/Ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits.

artículo científico

Glial Na(+) -dependent ion transporters in pathophysiological conditions.

artículo científico publicado en 2016

HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage

scientific article published on 07 November 2019

HIF-1alpha reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion.

artículo científico publicado en 2004

Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT.

artículo científico publicado en 2016

In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning

scientific article published on 19 September 2007

Involvement of the potassium-dependent sodium/calcium exchanger gene product NCKX2 in the brain insult induced by permanent focal cerebral ischemia.

artículo científico publicado en 2007

Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets

artículo científico publicado en 2018

Ionic homeostasis in brain conditioning

artículo científico publicado en 2015

Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype.

artículo científico publicado en 2014

MODELS AND METHODS FOR CONDITIONING THE ISCHEMIC BRAIN

artículo científico publicado en 2018

MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits

artículo científico publicado en 2014

Multicentre translational Trial of Remote Ischaemic Conditioning in Acute Ischaemic Stroke (TRICS): protocol of multicentre, parallel group, randomised, preclinical trial in female and male rat and mouse from the Italian Stroke Organization (ISO) Ba

artículo científico publicado en 2020

NCX as a key player in the neuroprotection exerted by ischemic preconditioning and postconditioning.

artículo científico

NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum

artículo científico publicado en 2015

NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.

artículo científico publicado en 2011

NCX1 is a new rest target gene: role in cerebral ischemia

artículo científico publicado en 2012

NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning.

artículo científico publicado en 2011

Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt

artículo científico publicado en 2015

Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants.

artículo científico publicado en 2006

Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion

artículo científico publicado en 2015

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1.

artículo científico publicado en 2015

Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options.

scientific article published on 07 June 2011

Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage

artículo científico publicado en 2012

New perspectives for selective NCX activators in neurodegenerative diseases

scientific article published on 07 February 2020

ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry

scientific article published on 01 May 2019

Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions.

artículo científico publicado en 2006

Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic bra

artículo científico publicado en 2015

Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives.

artículo científico publicado en 2004

Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation.

artículo científico publicado en 2018

Protective Effects of Quercetin on Rat Pial Microvascular Changes during Transient Bilateral Common Carotid Artery Occlusion and Reperfusion.

artículo científico publicado en 2012

Rhythm-specific modulation of the sensorimotor network in drug-naive patients with Parkinson's disease by levodopa

artículo científico publicado en 2013

Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism.

artículo científico publicado en 2015

Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced by Ischemic Preconditioning

artículo científico publicado en 2016

Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke

artículo científico publicado en 2018

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.

artículo científico publicado en 2012

Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.

artículo científico publicado en 2008

The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats.

artículo científico publicado en 2002

The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.

artículo científico publicado en 2010

Transgenic overexpression of adenosine kinase aggravates cell death in ischemia.

artículo científico publicado en 2006

Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.

artículo científico publicado en 2004

Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors.

artículo científico publicado en 2017

miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA

artículo científico publicado en 2020

ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia.

artículo científico publicado en 2007

Lista de obras de Giuseppe Pignataro

A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage.

Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases.

Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia

Alcohol increases spontaneous BOLD signal fluctuations in the visual network

Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats

Antithrombin reduces ischemic volume, ameliorates neurologic deficits, and prolongs animal survival in both transient and permanent focal ischemia.

Corrigendum to "NCX1 and NCX3: Two new effectors of delayed preconditioning in brain ischemia" [Neurobiol. Dis. 45 (2012) 616-623].

Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration

Does Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention?

Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism.

Editorial: Mechanisms of Innate Neuroprotection.

Effects of bone marrow mesenchymal stem cells (BM-MSCs) on rat pial microvascular remodeling after transient middle cerebral artery occlusion

Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype.

Genetically modified mice as a strategy to unravel the role played by the Na(+)/Ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits.

Glial Na(+) -dependent ion transporters in pathophysiological conditions.

HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage

HIF-1alpha reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion.

Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT.

In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning

Involvement of the potassium-dependent sodium/calcium exchanger gene product NCKX2 in the brain insult induced by permanent focal cerebral ischemia.

Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets

Ionic homeostasis in brain conditioning

Ischemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype.

MODELS AND METHODS FOR CONDITIONING THE ISCHEMIC BRAIN

MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits

Multicentre translational Trial of Remote Ischaemic Conditioning in Acute Ischaemic Stroke (TRICS): protocol of multicentre, parallel group, randomised, preclinical trial in female and male rat and mouse from the Italian Stroke Organization (ISO) Ba

NCX as a key player in the neuroprotection exerted by ischemic preconditioning and postconditioning.

NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum

NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.

NCX1 is a new rest target gene: role in cerebral ischemia

NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning.

Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt

Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants.

Neuroprotective Effect of VEGF-Mimetic Peptide QK in Experimental Brain Ischemia Induced in Rat by Middle Cerebral Artery Occlusion

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1.

Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options.

Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage

New perspectives for selective NCX activators in neurodegenerative diseases

ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry

Permanent focal brain ischemia induces isoform-dependent changes in the pattern of Na+/Ca2+ exchanger gene expression in the ischemic core, periinfarct area, and intact brain regions.

Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic bra

Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives.

Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation.

Protective Effects of Quercetin on Rat Pial Microvascular Changes during Transient Bilateral Common Carotid Artery Occlusion and Reperfusion.

Rhythm-specific modulation of the sensorimotor network in drug-naive patients with Parkinson's disease by levodopa

Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism.

Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced by Ischemic Preconditioning

Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.

Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.

The 2-oxopyrrolidinacetamide piracetam reduces infarct brain volume induced by permanent middle cerebral artery occlusion in male rats.

The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.

Transgenic overexpression of adenosine kinase aggravates cell death in ischemia.

Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.

Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors.

miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA

ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia.