Lista de obras - Sylvie Claeysen - Dominio Público Uruguay

5-HT(4) receptors, a place in the sun: act two.

artículo científico publicado en 2011

5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.

artículo científico publicado en 2012

5-HT4 receptors: cloning and expression of new splice variants.

artículo científico publicado en 1998

5-HT4 receptors: gene, transduction and effects on olfactory memory.

artículo científico publicado en 1998

5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling. ⬇️

artículo científico publicado en 2007

A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists.

artículo científico publicado en 2002

A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential

artículo científico publicado en 2019

A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.

artículo científico publicado en 2002

A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL).

artículo científico publicado en 2002

Alzheimer culprits: cellular crossroads and interplay.

artículo científico publicado en 2012

Assignment of 5-hydroxytryptamine receptor (HTR4) to human chromosome 5 bands q31-->q33 by in situ hybridization.

artículo científico publicado en 1997

Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation.

artículo científico publicado en 2010

Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling

artículo científico publicado en 2009

Cerebrovascular pathology during the progression of experimental Alzheimer's disease

artículo científico publicado en 2016

Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease

artículo científico publicado en 2017

Cloning and expression of human 5-HT4S receptors. Effect of receptor density on their coupling to adenylyl cyclase ⬇️

artículo científico publicado el 20 de octubre de 1997

Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors

artículo científico publicado en 2009

Constitutively active mutants of 5-HT4 receptors are they in unique active states?

artículo científico publicado en 2001

Donecopride, a Swiss army knife with potential against Alzheimer's disease

scientific article published on 27 December 2019

Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.

artículo científico publicado en 2005

Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease

artículo científico publicado en 2013

Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease

artículo científico publicado en 2019

Inhibition of glucose-induced insulin secretion by a peripheral-type benzodiazepine receptor ligand (PK11195)

scientific article published on 01 July 2000

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases.

artículo científico publicado en 2016

Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation.

artículo científico publicado en 2006

Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease

artículo científico publicado en 2019

Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride

artículo científico publicado en 2015

Pharmacological profile of engineered 5-HT4 receptors and identification of 5-HT4 receptor-biased ligands ⬇️

artículo científico publicado el 10 de noviembre de 2012

Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs.

artículo científico publicado en 2017

Primary culture of mouse dopaminergic neurons

artículo científico publicado en 2014

Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer's disease

artículo científico publicado en 2020

SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation

artículo científico publicado en 2014

Serotonin Type 4 Receptor Dimers

artículo científico publicado en 2013

Serotonin: A New Hope in Alzheimer's Disease?

artículo científico publicado en 2015

Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.

artículo científico publicado en 2005

Lista de obras de Sylvie Claeysen

5-HT(4) receptors, a place in the sun: act two.

5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.

5-HT4 receptors: cloning and expression of new splice variants.

5-HT4 receptors: gene, transduction and effects on olfactory memory.

5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling. ⬇️

A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists.

A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential

A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.

A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL).

Alzheimer culprits: cellular crossroads and interplay.

Assignment of 5-hydroxytryptamine receptor (HTR4) to human chromosome 5 bands q31-->q33 by in situ hybridization.

Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation.

Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling

Cerebrovascular pathology during the progression of experimental Alzheimer's disease

Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease

Cloning and expression of human 5-HT4S receptors. Effect of receptor density on their coupling to adenylyl cyclase ⬇️

Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors

Constitutively active mutants of 5-HT4 receptors are they in unique active states?

Donecopride, a Swiss army knife with potential against Alzheimer's disease

Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.

Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease

Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease

Inhibition of glucose-induced insulin secretion by a peripheral-type benzodiazepine receptor ligand (PK11195)

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases.

Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation.

Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease

Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride

Pharmacological profile of engineered 5-HT4 receptors and identification of 5-HT4 receptor-biased ligands ⬇️

Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs.

Primary culture of mouse dopaminergic neurons

Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer's disease

SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation

Serotonin Type 4 Receptor Dimers

Serotonin: A New Hope in Alzheimer's Disease?

Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.