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Lista de obras de Victor H Engelhard

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

artículo científico publicado en 2016

A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule.

artículo científico publicado en 1996

A naturally processed peptide presented by HLA-A*0201 is expressed at low abundance and recognized by an alloreactive CD8+ cytotoxic T cell with apparent high affinity.

artículo científico publicado en 1997

A single amino acid substitution in HLA-A2 can alter the selection of the cytotoxic T lymphocyte repertoire that responds to influenza virus matrix peptide 55-73.

artículo científico publicado en 1989

Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics.

artículo científico publicado en 2008

Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation

artículo científico publicado en 2006

Alloreactive cytotoxic T lymphocytes focus on specific major histocompatibility complex-bound peptides

scientific article published on 01 July 1997

Antibiotics Drive Microbial Imbalance and Vitiligo Development in Mice

artículo científico publicado en 2019

Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells.

artículo científico publicado en 2003

Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy

artículo científico publicado en 2002

CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptors

artículo científico publicado en 2010

Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy.

artículo científico publicado en 2018

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

artículo científico publicado el 6 de marzo de 1992

Class I-restricted alloreactive cytotoxic T lymphocytes recognize a complex array of specific MHC-associated peptides.

artículo científico publicado en 1998

Comparative Transcriptomic Analysis Identifies a Range of Immunologically Related Functional Elaborations of Lymph Node Associated Lymphatic and Blood Endothelial Cells

artículo científico publicado en 2019

Competition among peptides in melanoma vaccines for binding to MHC molecules

artículo científico publicado en 2004

Complete primary structure of human histocompatibility antigen HLA-B7: evolutionary and functional implications

scientific article published on 01 January 1980

Construction of novel class I histocompatibility antigens by interspecies exon shuffling.

artículo científico publicado en 1985

Control of CD8 T-Cell Infiltration into Tumors by Vasculature and Microenvironment

artículo científico publicado en 2015

Creating new peptide antigens by slicing and splicing proteins

artículo científico publicado en 2004

Cytotoxic T lymphocyte recognition of HLA-A/B antigens introduced into EL4 cells by cell-liposome fusion.

artículo científico publicado en 1984

Cytotoxic T lymphocyte-defined epitope differences between HLA-A2.1 and HLA-A2.2 map to two distinct regions of the molecule.

artículo científico publicado en 1988

Cytotoxic T lymphocytes from HLA-A2 transgenic mice specific for HLA-A2 expressed on human cells.

artículo científico publicado en 1988

Cytotoxic activity and lymphokine production of T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ cytotoxic T lymphocyte (CTL) clones recognizing HLA-A2 and HLA-A2 mutants. Recognition of TCR-gamma delta+ CTL clones is affected by mutations at

artículo científico publicado en 1990

Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding

scientific article published on 01 January 1987

Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells.

artículo científico publicado en 2007

Derivation of cytotoxic T cell lines that express T cell receptor but exhibit reversible loss of stable antigen binding

artículo científico publicado en 1986

Determination of intronic sequences adjacent to an exon using polymerase chain reaction and genomic DNA library constructed by TA cloning.

artículo científico publicado en 2001

Differential Expression of Homing Receptor Ligands on Tumor-Associated Vasculature that Control CD8 Effector T-cell Entry.

artículo científico publicado en 2017

Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells.

artículo científico publicado en 1993

Direct identification of tumor-associated peptide antigens.

artículo científico publicado en 1996

Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling.

artículo científico publicado en 2003

Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases

scientific article published on 01 January 2008

Diversity and dominance among TCR recognizing HLA-A2.1+ influenza matrix peptide in human MHC class I transgenic mice.

artículo científico publicado en 1994

Effect of membrane phospholipid compositional changes on adenylate cyclase in LM cells.

artículo científico publicado en 1978

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity

artículo científico publicado en 2015

Enhanced in vitro potency and in vivo immunogenicity of a CTL epitope from hepatitis C virus core protein following amino acid replacement at secondary HLA-A2.1 binding positions

artículo científico publicado en 1998

Evaluation of peptide vaccine immunogenicity in draining lymph nodes and peripheral blood of melanoma patients.

artículo científico publicado en 2001

Fas-independent apoptosis of activated T cells induced by antibodies to the HLA class I alpha1 domain

artículo científico publicado en 1997

Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens.

artículo científico publicado en 2002

Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

artículo científico publicado en 2018

HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

artículo científico publicado el 6 de marzo de 1992

How cells process antigens.

artículo científico publicado en 1994

Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development.

artículo científico publicado en 1998

Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma.

artículo científico publicado en 2016

Identification and Characterization of Tertiary Lymphoid Structures in Murine Melanoma

artículo científico publicado en 2018

Identification by mass spectrometry of CD8(+)-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product

artículo científico publicado en 2002

Identification by site-directed mutagenesis of amino acid residues contributing to serologic and CTL-defined epitope differences between HLA-A2.1 and HLA-A2.3.

artículo científico publicado en 1988

Identification of a graft versus host disease-associated human minor histocompatibility antigen

scientific article published in Science

Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

artículo científico publicado en 1994

Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism.

artículo científico publicado en 1996

Identification of a shared epitope recognized by melanoma-specific, HLA-A3-restricted cytotoxic T lymphocytes

artículo científico publicado en 2003

Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy

artículo científico publicado en 2006

Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: distinct characteristics correlated with CD8 dependence

scientific article published on 01 February 2001

Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma

artículo científico publicado en 2004

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

artículo científico publicado en 2018

Immune responses in a mouse model of vitiligo with spontaneous epidermal de- and repigmentation.

artículo científico publicado en 2014

Immune responses to the HLA-A*0201-restricted epitopes of tyrosinase and glycoprotein 100 enable control of melanoma outgrowth in HLA-A*0201-transgenic mice.

artículo científico publicado en 2001

Immunity to melanoma antigens: from self-tolerance to immunotherapy

artículo científico publicado en 2006

Importance of MHC class 1 alpha2 and alpha3 domains in the recognition of self and non-self MHC molecules.

artículo científico publicado en 1996

Induction of secondary cytotoxic T lymphocytes by liposomes containing HLA-DR antigens.

artículo científico publicado en 1980

Induction of secondary cytotoxic T lymphocytes by purified HLA-A and HLA-B antigens reconstituted into phospholipid vesicles

artículo científico publicado el 1 de noviembre de 1978

Influenza A-specific, HLA-A2.1-restricted cytotoxic T lymphocytes from HLA-A2.1 transgenic mice recognize fragments of the M1 protein

artículo científico publicado el 15 de febrero de 1991

Inhibition of T cell activation by a monoclonal antibody reactive against the alpha 3 domain of human MHC class I molecules

artículo científico publicado en 1994

Insights into antigen processing gained by direct analysis of the naturally processed class I MHC associated peptide repertoire

artículo científico publicado en 2002

Introduction of HLA-A/B antigens into lymphoid cell membranes by cell-liposome fusion

artículo científico publicado en 1984

Isolation and characterization of monoclonal mouse cytotoxic T lymphocytes with specificity for HLA-A,B or -DR alloantigens

artículo científico publicado en 1982

Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes.

artículo científico publicado en 2006

Lipopeptide-based melanoma cancer vaccine induced a strong MART-27-35-cytotoxic T lymphocyte response in a preclinal study.

artículo científico publicado en 2002

Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

artículo científico publicado en 2010

Lymphatic endothelial cells - key players in regulation of tolerance and immunity

artículo científico publicado en 2012

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

artículo científico publicado en 2012

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

artículo científico publicado en 2013

MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.

artículo científico publicado en 2008

MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma

scientific article published on 01 May 2020

MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer

artículo científico publicado en 2014

Manipulation of Avidity to Improve Effectiveness of Adoptively Transferred CD8+ T Cells for Melanoma Immunotherapy in Human MHC Class I-Transgenic Mice

artículo científico publicado el 15 de noviembre de 2001

Mass-spectrometric evaluation of HLA-A*0201-associated peptides identifies dominant naturally processed forms of CTL epitopes from MART-1 and gp100.

artículo científico publicado en 1999

Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice

artículo científico publicado en 2010

Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.

artículo científico publicado en 2000

Modification of adenylate cyclase activity in LM cells by manipulation of the membrane phospholipid composition in vivo

artículo científico publicado el 1 de diciembre de 1976

Multiple epitopes on human and murine cells expressing HLA-B7 as defined by specific murine cytotoxic T cell clones

scientific article published on 01 August 1985

N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase

artículo científico publicado en 2009

Negative cooperativity exhibited by prostaglandin E1 stimulated adenylate cyclase in LM cells

artículo científico publicado el 28 de noviembre de 1978

Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors

artículo científico publicado en 2019

Peptide and dendritic cell vaccines

artículo científico publicado en 2006

Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells

artículo científico publicado el 1 de septiembre de 1997

Peripheral tissue homing receptor control of naïve, effector, and memory CD8 T cell localization in lymphoid and non-lymphoid tissues

artículo científico publicado en 2013

Peripheral tissue homing receptors enable T cell entry into lymph nodes and affect the anatomical distribution of memory cells

artículo científico publicado en 2013

Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes.

artículo científico publicado en 2001

Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo

artículo científico publicado en 2000

Post-translational modifications of naturally processed MHC-binding epitopes

artículo científico publicado en 2005

Preventing the spontaneous modification of an HLA-A2-restricted peptide at an N-terminal glutamine or an internal cysteine residue enhances peptide antigenicity

artículo científico publicado en 2004

Prevention of diabetes in BB rats. I. Evidence suggesting a requirement for mature T cells in bone marrow inoculum of neonatally injected rats

artículo científico publicado en 1986

Prevention of diabetes in the BB rat by injection of major histocompatibility complex- (MHC-) compatible bone marrow cells.

artículo científico publicado en 1988

Probing HLA-B7 conformational shifts induced by peptide-binding groove mutations and bound peptide with anti-HLA monoclonal antibodies.

artículo científico publicado en 1996

Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases.

artículo científico publicado en 2006

Production of cyclic AMP from extracellular ATP by intact LM cells

artículo científico publicado el 19 de febrero de 1979

Prophylactic DNA vaccine for hepatitis C virus (HCV) infection: HCV-specific cytotoxic T lymphocyte induction and protection from HCV-recombinant vaccinia infection in an HLA-A2.1 transgenic mouse model.

artículo científico publicado en 2000

Proteasomes can either generate or destroy MHC class I epitopes: evidence for nonproteasomal epitope generation in the cytosol

artículo científico publicado el 1 de julio de 1998

Recognition of human melanoma cells by HLA-A2.1-restricted cytotoxic T lymphocytes is mediated by at least six shared peptide epitopes

artículo científico publicado el 1 de abril de 1993

Reconstitution of purified detergent-soluble HLA-A and HLA-B antigens into phospholipid vesicles

artículo científico publicado el 1 de julio de 1978

Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.

artículo científico publicado en 2005

Regulation of T-cell Tolerance by Lymphatic Endothelial Cells.

artículo científico publicado en 2014

Regulatory T cells and vasectomy

artículo científico publicado en 2013

Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity

artículo científico publicado en 2013

Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography

scientific article published on 01 January 1986

Retraction

artículo científico publicado en 2001

Role of endogenous peptide in human alloreactive cytotoxic T cell responses

artículo científico publicado el 1 de marzo de 1992

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction

artículo científico publicado en 2015

Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control

artículo científico publicado en 2003

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

artículo científico publicado en 2009

Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: implications for tumor immunotherapy

artículo científico publicado en 2000

Several HLA alleles share overlapping peptide specificities.

artículo científico publicado en 1995

Species specificity and augmentation of responses to class II major histocompatibility complex molecules in human CD4 transgenic mice

artículo científico publicado el 1 de junio de 1992

Species specificity in the interaction of CD8 with the alpha 3 domain of MHC class I molecules

artículo científico publicado el 1 de julio de 1992

Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles

scientific article published on 01 August 1980

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

scientific journal article

Strategies and challenges in eliciting immunity to melanoma

artículo científico publicado en 2008

Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells

artículo científico publicado en 2010

Structure of peptides associated with MHC class I molecules.

artículo científico publicado en 1994

Subcellular location of adenylate cyclase in rat cardiac muscle

artículo científico publicado el 18 de noviembre de 1976

Tapasin is a facilitator, not an editor, of class I MHC peptide binding.

artículo científico publicado en 2003

Targeting Fel d 1 to FcgammaRI induces a novel variation of the T(H)2 response in subjects with cat allergy.

artículo científico publicado en 2007

Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor.

artículo científico publicado en 2010

Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27-35) peptide: implications for peptide vaccines.

artículo científico publicado en 1999

The Class I Antigen-processing Pathway for the Membrane Protein Tyrosinase Involves Translation in the Endoplasmic Reticulum and Processing in the Cytosol

artículo científico publicado el 5 de enero de 1998

The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.

artículo científico publicado en 2001

The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL.

artículo científico publicado en 2006

The ability of cytotoxic T cells to recognize HLA-A2.1 or HLA-B7 antigens expressed on murine cells correlates with their epitope specificity.

artículo científico publicado en 1987

The contributions of mass spectrometry to understanding of immune recognition by T lymphocytes

artículo científico publicado en 2007

The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68

artículo científico publicado en 1997

The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism.

artículo científico publicado en 1998

The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein

artículo científico publicado en 2003

The peptide recognized by HLA-A68.2-restricted, squamous cell carcinoma of the lung-specific cytotoxic T lymphocytes is derived from a mutated elongation factor 2 gene.

artículo científico publicado en 1998

The role of K+ in the regulation of the increase in intracellular Ca2+ mediated by the T lymphocyte antigen receptor

artículo científico publicado en 1987

Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment

artículo científico publicado en 2014

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

artículo científico publicado en 2010

Tyrosinase degradation via two pathways during reverse translocation to the cytosol.

artículo científico publicado en 2001

Xenogeneic cytotoxic T-cell clones recognize alloantigenic determinants on HLA-A2

artículo científico publicado el 1 de enero de 1983