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Lista de obras de Sahil Seth

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases

scientific article published on 01 July 2018

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

artículo científico publicado en 2017

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

artículo científico publicado en 2015

A functional genomic approach to actionable gene fusions for precision oncology

artículo científico publicado en 2022

Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib

scientific article published on 14 September 2020

Characterization of HPV and host genome interactions in primary head and neck cancers

artículo científico publicado en 2014

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

artículo científico publicado en 2018

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

artículo científico publicado en 2017

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

scientific article published on 01 January 2019

Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer

artículo científico publicado en 2015

Global impact of somatic structural variation on the DNA methylome of human cancers

artículo científico publicado en 2019

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

artículo científico publicado en 2018

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

artículo científico publicado en 2014

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

artículo científico publicado en 2016

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

artículo científico publicado en 2021

Mutational landscape of aggressive cutaneous squamous cell carcinoma

artículo científico publicado en 2014

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

artículo científico publicado en 2014

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

scientific article published on 01 February 2019

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

artículo científico publicado en 2014

Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state

scientific article published on 01 April 2019

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

artículo científico publicado en 2020

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

scientific article published on 27 March 2019

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

artículo científico publicado en 2017

Systematic analysis of telomere length and somatic alterations in 31 cancer types.

artículo científico publicado en 2017

The somatic genomic landscape of chromophobe renal cell carcinoma

artículo científico publicado en 2014

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