Lista de obras - Judy B de Haan - Dominio Público Uruguay

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

scientific article published on 01 October 2018

A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy.

artículo científico publicado en 2016

Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse ⬇️

artículo científico publicado el 7 de septiembre de 2010

Are reactive oxygen species still the basis for diabetic complications?

artículo científico

Changes in the levels of enzymes which modulate the antioxidant balance occur during aging and correlate with cellular damage

scientific article published on 01 May 1995

Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much?

artículo científico

Corrigendum to "Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium" [Vasc. Pharmacol. 79 (2016) 32-42].

artículo científico publicado en 2017

Corrigendum to “Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice” [Atherosclerosis 243/2 (2015) 598–608]

artículo científico publicado en 2016

Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains

artículo científico publicado el 1 de abril de 1992

Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease

artículo científico publicado en 2014

Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis.

artículo científico publicado en 2015

Does lack of glutathione peroxidase 1 gene expression exacerbate lung injury induced by neonatal hyperoxia in mice?

artículo científico publicado en 2017

Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina

artículo científico publicado en 2015

Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE-/- mice.

artículo científico publicado en 2012

Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide.

artículo científico publicado en 1996

Ensuring animal welfare while meeting scientific aims using a murine pneumonia model of septic shock.

artículo científico publicado en 2013

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

scientific journal article

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

artículo científico publicado en 2009

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets

artículo científico publicado en 2015

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

scientific journal article

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

artículo científico publicado en 2017

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

scientific journal article

Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium.

artículo científico publicado en 2015

Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice

scientific article published on 09 April 2007

Lack of the antioxidant glutathione peroxidase-1 (GPx1) exacerbates retinopathy of prematurity in mice.

artículo científico publicado en 2013

Lack of the antioxidant glutathione peroxidase-1 does not increase atherosclerosis in C57BL/J6 mice fed a high-fat diet.

artículo científico publicado en 2006

Late-intervention study with ebselen in an experimental model of type 1 diabetic nephropathy.

artículo científico publicado en 2015

Limiting reductive stress for treating in-stent stenosis: the heart of the matter?

artículo científico publicado en 2014

Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii

artículo científico publicado el 1 de enero de 1992

Mice lacking glutathione peroxidase-1 activity show increased TUNEL staining and an accelerated inflammatory response in brain following a cold-induced injury.

artículo científico publicado en 2002

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

artículo científico publicado en 1998

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

artículo científico publicado en 2013

Nanoporous Metal-Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide

artículo científico publicado en 2015

Novel pathways and therapies in experimental diabetic atherosclerosis ⬇️

artículo científico publicado el 1 de marzo de 2012

Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic Retinopathy

artículo científico publicado en 2018

Nrf2 activators as attractive therapeutics for diabetic nephropathy.

artículo científico publicado en 2011

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications.

artículo científico publicado en 2018

Oxidative stress in surgery in an ageing population: pathophysiology and therapy.

artículo científico publicado en 2012

Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice.

artículo científico publicado en 2015

Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock

artículo científico publicado en 2016

Recent novel approaches to limit oxidative stress and inflammation in diabetic complications.

artículo científico publicado en 2018

Retinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1

scientific journal article

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.

artículo científico publicado en 2009

Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic Nephropathy

artículo científico publicado en 2015

Targeting Oxidative Stress in Diabetic Complications: New Insights

artículo científico publicado en 2018

Targeting endothelial dysfunction in vascular complications associated with diabetes

artículo científico publicado en 2011

The ethical dimension in published animal research in critical care: the dark side of our moon

artículo científico

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction.

artículo científico publicado en 2017

The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy

artículo científico publicado en 2017

What effect does regular exercise have on oxidative stress in people with Down syndrome? A systematic review with meta-analyses.

artículo científico publicado en 2017

Lista de obras de Judy B de Haan

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy.

Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse ⬇️

Are reactive oxygen species still the basis for diabetic complications?

Changes in the levels of enzymes which modulate the antioxidant balance occur during aging and correlate with cellular damage

Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much?

Corrigendum to "Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium" [Vasc. Pharmacol. 79 (2016) 32-42].

Corrigendum to “Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice” [Atherosclerosis 243/2 (2015) 598–608]

Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains

Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease

Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis.

Does lack of glutathione peroxidase 1 gene expression exacerbate lung injury induced by neonatal hyperoxia in mice?

Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina

Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE-/- mice.

Elevation in the ratio of Cu/Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide.

Ensuring animal welfare while meeting scientific aims using a murine pneumonia model of septic shock.

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

Imatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

Kidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathy

Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium.

Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice

Lack of the antioxidant glutathione peroxidase-1 (GPx1) exacerbates retinopathy of prematurity in mice.

Lack of the antioxidant glutathione peroxidase-1 does not increase atherosclerosis in C57BL/J6 mice fed a high-fat diet.

Late-intervention study with ebselen in an experimental model of type 1 diabetic nephropathy.

Limiting reductive stress for treating in-stent stenosis: the heart of the matter?

Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii

Mice lacking glutathione peroxidase-1 activity show increased TUNEL staining and an accelerated inflammatory response in brain following a cold-induced injury.

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

Nanoporous Metal-Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide

Novel pathways and therapies in experimental diabetic atherosclerosis ⬇️

Nrf2 Activation Is a Potential Therapeutic Approach to Attenuate Diabetic Retinopathy

Nrf2 activators as attractive therapeutics for diabetic nephropathy.

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications.

Oxidative stress in surgery in an ageing population: pathophysiology and therapy.

Plasmalogen modulation attenuates atherosclerosis in ApoE- and ApoE/GPx1-deficient mice.

Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock

Recent novel approaches to limit oxidative stress and inflammation in diabetic complications.

Retinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.

Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic Nephropathy

Targeting Oxidative Stress in Diabetic Complications: New Insights

Targeting endothelial dysfunction in vascular complications associated with diabetes

The ethical dimension in published animal research in critical care: the dark side of our moon

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction.

The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy

What effect does regular exercise have on oxidative stress in people with Down syndrome? A systematic review with meta-analyses.