Lista de obras - Darren N Saunders - Dominio Público Uruguay

A high-throughput, multiplex cell death assay using an RNAi screening approach

artículo científico publicado en 2014

A novel SERPINA1 mutation causing serum alpha(1)-antitrypsin deficiency

artículo científico publicado en 2012

A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells

artículo científico publicado en 2007

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

artículo científico publicado en 2017

Adipocyte-Tumor Cell Metabolic Crosstalk in Breast Cancer

artículo científico publicado en 2017

Backlogged system in Australia shuts out new investigators

article

Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers.

artículo científico publicado en 2016

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

artículo científico publicado en 2017

Cancer in the news: Bias and quality in media reporting of cancer research

artículo científico publicado en 2020

Correction: Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

artículo científico publicado en 2017

Crystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loop

artículo científico publicado en 2001

Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of SerpinE1 and SerpinB2 in cancer

artículo científico publicado en 2011

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

artículo científico publicado en 2015

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

artículo científico publicado en 2012

EDD mediates DNA damage-induced activation of CHK2

artículo científico publicado en 2006

Edd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion

artículo científico publicado en 2004

Effects of EDD on p53 function are context-specific

artículo científico publicado en 2011

Experimental design for stable genetic manipulation in mammalian cell lines: lentivirus and alternatives

artículo científico publicado en 2014

Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer

artículo científico

Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers.

artículo científico publicado en 2010

High-throughput approaches to measuring cell death

artículo científico publicado en 2014

Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases

artículo científico publicado en 2016

Immunological Detection of Conformational Neoepitopes Associated with the Serpin Activity of Plasminogen Activator Inhibitor Type-2

scientific article published on 01 May 1998

Improving the Delivery of SOD1 Antisense Oligonucleotides to Motor Neurons Using Calcium Phosphate-Lipid Nanoparticles.

artículo científico publicado en 2017

Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

artículo científico publicado en 2017

Intensity calibration and automated cell cycle gating for high-throughput image-based siRNA screens of mammalian cells

artículo científico publicado en 2008

Interaction between the P14 residue and strand 2 of beta-sheet B is critical for reactive center loop insertion in plasminogen activator inhibitor-2.

artículo científico publicado en 2001

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

artículo científico publicado en 2013

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

scientific journal article

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

scientific article published on 01 June 2020

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

artículo científico publicado en 2004

Microsurgical access for cell injection into the mammalian cochlea

artículo científico publicado en 2007

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

scientific article published on 30 January 2017

Modulation of myocardin function by the ubiquitin E3 ligase UBR5

artículo científico publicado en 2011

Modulation of myocardin function by the ubiquitin E3 ligase UBR5.

artículo científico publicado en 2010

N-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

artículo científico publicado en 2020

Plasminogen activator inhibitor type 2 inhibits cell surface associated tissue plasminogen activator in vitro

artículo científico publicado en 2008

Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity

artículo científico publicado en 2007

Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor

artículo científico publicado en 2007

Regulation of primary cilia formation by the ubiquitin-proteasome system

artículo científico publicado en 2016

Revisiting the biological roles of PAI2 (SERPINB2) in cancer

artículo científico publicado en 2008

SOD1A4Vaggregation alters ubiquitin homeostasis in a cell model of ALS

artículo científico publicado en 2018

Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer

artículo científico publicado en 2007

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

artículo científico publicado en 2015

Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.

artículo científico publicado en 2017

Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2.

artículo científico publicado en 2014

Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomas

artículo científico publicado en 2010

Systematic approaches to identify E3 ligase substrates

artículo científico publicado en 2016

TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

artículo científico publicado en 2012

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro

artículo científico publicado en 2008

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.

artículo científico publicado en 2008

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

artículo científico publicado en 2019

The Urokinase/PAI-2 Complex

artículo científico publicado en 2006

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities

artículo científico publicado en 2018

Walking the tightrope: proteostasis and neurodegenerative disease

artículo científico publicado en 2016

Lista de obras de Darren N Saunders

A high-throughput, multiplex cell death assay using an RNAi screening approach

A novel SERPINA1 mutation causing serum alpha(1)-antitrypsin deficiency

A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

Adipocyte-Tumor Cell Metabolic Crosstalk in Breast Cancer

Backlogged system in Australia shuts out new investigators

Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers.

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Cancer in the news: Bias and quality in media reporting of cancer research

Correction: Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

Crystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loop

Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of SerpinE1 and SerpinB2 in cancer

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

EDD mediates DNA damage-induced activation of CHK2

Edd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion

Effects of EDD on p53 function are context-specific

Experimental design for stable genetic manipulation in mammalian cell lines: lentivirus and alternatives

Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer

Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers.

High-throughput approaches to measuring cell death

Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases

Immunological Detection of Conformational Neoepitopes Associated with the Serpin Activity of Plasminogen Activator Inhibitor Type-2

Improving the Delivery of SOD1 Antisense Oligonucleotides to Motor Neurons Using Calcium Phosphate-Lipid Nanoparticles.

Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

Intensity calibration and automated cell cycle gating for high-throughput image-based siRNA screens of mammalian cells

Interaction between the P14 residue and strand 2 of beta-sheet B is critical for reactive center loop insertion in plasminogen activator inhibitor-2.

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta

MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

Microsurgical access for cell injection into the mammalian cochlea

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

Modulation of myocardin function by the ubiquitin E3 ligase UBR5

Modulation of myocardin function by the ubiquitin E3 ligase UBR5.

N-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

Plasminogen activator inhibitor type 2 inhibits cell surface associated tissue plasminogen activator in vitro

Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity

Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor

Regulation of primary cilia formation by the ubiquitin-proteasome system

Revisiting the biological roles of PAI2 (SERPINB2) in cancer

SOD1A4Vaggregation alters ubiquitin homeostasis in a cell model of ALS

Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.

Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2.

Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomas

Systematic approaches to identify E3 ligase substrates

TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

The Urokinase/PAI-2 Complex

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities

Walking the tightrope: proteostasis and neurodegenerative disease