Lista de obras - Michael J Courtney - Dominio Público Uruguay

A simple optogenetic MAPK inhibitor design reveals resonance between transcription-regulating circuitry and temporally-encoded inputs.

artículo científico publicado en 2017

ARHGAP12 Functions as a Developmental Brake on Excitatory Synapse Function

artículo científico publicado en 2016

All JNKs Can Kill, but Nuclear Localization Is Critical for Neuronal Death

scientific article published in Journal of Biological Chemistry

Alpha2B-adrenoceptors couple to Ca2+ increase in both endogenous and recombinant expression systems.

artículo científico publicado en 1998

Brain derived neurotrophic factor induces a rapid upregulation of synaptophysin and tau proteins via the neurotrophin receptor TrkB in rat cerebellar granule cells.

artículo científico publicado en 1997

Ca2+-dependent potentiation of muscarinic receptor-mediated Ca2+ elevation

artículo científico publicado en 2004

Calpains are downstream effectors of bax-dependent excitotoxic apoptosis.

artículo científico publicado en 2012

Concurrent protective and destructive signaling of JNK2 in neuroblastoma cells

artículo científico publicado en 2009

Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector

scientific journal article

Coupling of astroglial alpha 2-adrenoreceptors to second messenger pathways

artículo científico publicado en 1996

Cysteine 893 is a target of regulatory thiol modifications of GluA1 AMPA receptors.

artículo científico publicado en 2017

Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice

artículo científico publicado en 2018

Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

artículo científico publicado en 2004

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

artículo científico publicado en 2000

Efficient Binding of the NOS1AP C-Terminus to the nNOS PDZ Pocket Requires the Concerted Action of the PDZ Ligand Motif, the Internal ExF Site and Structural Integrity of an Independent Element

artículo científico publicado en 2017

Establishing an effective dose for chronic intracerebroventricular administration of clozapine in mice

artículo científico publicado en 2019

Ethanol Specifically Inhibits NMDA Receptors with Affinity for Ifenprodil in the Low Micromolar Range in Cultured Cerebellar Granule Cells ⬇️

artículo científico publicado el 1 de noviembre de 1997

Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.

artículo científico publicado en 2003

Hippocampal long-term depression is enhanced, depotentiation is inhibited and long-term potentiation is unaffected by the application of a selective c-Jun N-terminal kinase inhibitor to freely behaving rats.

artículo científico publicado en 2011

Inhibition of Excessive Oxidative Protein Folding Is Protective in MPP(+) Toxicity-Induced Parkinson's Disease Models

artículo científico publicado en 2016

Interactions between phospholipase C-coupled and N-methyl-D-aspartate receptors in cultured cerebellar granule cells: protein kinase C mediated inhibition of N-methyl-D-aspartate responses

artículo científico publicado el 1 de septiembre de 1992

Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3.

artículo científico publicado en 2003

Localization of voltage-sensitive Ca2+ fluxes and neuropeptide Y immunoreactivity to varicosities in SH-SY5Y human neuroblastoma cells differentiated by treatment with the protein kinase inhibitor staurosporine.

artículo científico publicado en 1997

Mechanisms of NOS1AP action on NMDA receptor-nNOS signaling

artículo científico

Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.

artículo científico publicado en 1991

Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway

artículo científico publicado en 2014

Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism

artículo científico publicado en 1997

Rapid Ca 2+ Mobilization in Single LGL Cells upon Interaction with K562 Target Cells--Role of the CD18 and CD16 Molecules

artículo científico publicado en 1995

Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation

artículo científico publicado en 2008

Redox-Activated Signal Transduction Pathways Mediating Cellular Functions in Inflammation, Differentiation, Degeneration, Transformation, and Death.

artículo científico publicado en 2016

Regulation of SAPKs in CNS neurons.

artículo científico publicado en 1997

Resonance energy transfer sensitises and monitors in situ switching of LOV2-based optogenetic actuators

scientific article published on 09 October 2020

Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death

scientific journal article

Spatial quantification of the synaptic activity phenotype across large populations of neurons with Markov random fields

Superior cervical ganglion-10 protein as a molecular effector of c-Jun N-terminal kinase 1: implications for the therapeutic targeting of Jun N-terminal kinase in nerve regeneration

artículo científico publicado en 2008

The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death

artículo científico publicado en 2005

The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death

artículo científico publicado en 2008

The calcium response to the excitotoxin kainate is amplified by subsequent reduction of extracellular sodium

artículo científico publicado en 1995

The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells

artículo científico publicado en 1990

The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death

scientific journal article

The role of topoisomerase II in the excision of DNA loop domains during apoptosis

artículo científico publicado en 2002

Unexpected Heterodivalent Recruitment of NOS1AP to nNOS Reveals Multiple Sites for Pharmacological Intervention in Neuronal Disease Models.

artículo científico publicado en 2015

ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability

scholarly article published in Molecular Pain

c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells

artículo científico publicado en 2012

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

artículo científico publicado en 2002

Lista de obras de Michael J Courtney

A simple optogenetic MAPK inhibitor design reveals resonance between transcription-regulating circuitry and temporally-encoded inputs.

ARHGAP12 Functions as a Developmental Brake on Excitatory Synapse Function

All JNKs Can Kill, but Nuclear Localization Is Critical for Neuronal Death

Alpha2B-adrenoceptors couple to Ca2+ increase in both endogenous and recombinant expression systems.

Brain derived neurotrophic factor induces a rapid upregulation of synaptophysin and tau proteins via the neurotrophin receptor TrkB in rat cerebellar granule cells.

Ca2+-dependent potentiation of muscarinic receptor-mediated Ca2+ elevation

Calpains are downstream effectors of bax-dependent excitotoxic apoptosis.

Concurrent protective and destructive signaling of JNK2 in neuroblastoma cells

Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector

Coupling of astroglial alpha 2-adrenoreceptors to second messenger pathways

Cysteine 893 is a target of regulatory thiol modifications of GluA1 AMPA receptors.

Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice

Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

Efficient Binding of the NOS1AP C-Terminus to the nNOS PDZ Pocket Requires the Concerted Action of the PDZ Ligand Motif, the Internal ExF Site and Structural Integrity of an Independent Element

Establishing an effective dose for chronic intracerebroventricular administration of clozapine in mice

Ethanol Specifically Inhibits NMDA Receptors with Affinity for Ifenprodil in the Low Micromolar Range in Cultured Cerebellar Granule Cells ⬇️

Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.

Hippocampal long-term depression is enhanced, depotentiation is inhibited and long-term potentiation is unaffected by the application of a selective c-Jun N-terminal kinase inhibitor to freely behaving rats.

Inhibition of Excessive Oxidative Protein Folding Is Protective in MPP(+) Toxicity-Induced Parkinson's Disease Models

Interactions between phospholipase C-coupled and N-methyl-D-aspartate receptors in cultured cerebellar granule cells: protein kinase C mediated inhibition of N-methyl-D-aspartate responses

Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3.

Localization of voltage-sensitive Ca2+ fluxes and neuropeptide Y immunoreactivity to varicosities in SH-SY5Y human neuroblastoma cells differentiated by treatment with the protein kinase inhibitor staurosporine.

Mechanisms of NOS1AP action on NMDA receptor-nNOS signaling

Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.

Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway

Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism

Rapid Ca 2+ Mobilization in Single LGL Cells upon Interaction with K562 Target Cells--Role of the CD18 and CD16 Molecules

Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation

Redox-Activated Signal Transduction Pathways Mediating Cellular Functions in Inflammation, Differentiation, Degeneration, Transformation, and Death.

Regulation of SAPKs in CNS neurons.

Resonance energy transfer sensitises and monitors in situ switching of LOV2-based optogenetic actuators

Rho mediates calcium-dependent activation of p38alpha and subsequent excitotoxic cell death

Spatial quantification of the synaptic activity phenotype across large populations of neurons with Markov random fields

Superior cervical ganglion-10 protein as a molecular effector of c-Jun N-terminal kinase 1: implications for the therapeutic targeting of Jun N-terminal kinase in nerve regeneration

The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death

The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death

The calcium response to the excitotoxin kainate is amplified by subsequent reduction of extracellular sodium

The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells

The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death

The role of topoisomerase II in the excision of DNA loop domains during apoptosis

Unexpected Heterodivalent Recruitment of NOS1AP to nNOS Reveals Multiple Sites for Pharmacological Intervention in Neuronal Disease Models.

ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability

c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.