Lista de obras - Manu De Rycker - Dominio Público Uruguay

2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease

artículo científico publicado en 2018

A high-content, cell-based screen identifies micropolyin, a new inhibitor of microtubule dynamics

artículo científico publicado en 2009

A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes

artículo científico publicado en 2012

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

artículo científico publicado en 2017

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

artículo científico publicado en 2017

Author Correction: Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

artículo científico publicado en 2018

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

artículo científico publicado en 2017

Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay

artículo científico publicado en 2013

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

scientific article published in Nature

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.

artículo científico publicado en 2015

Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery

scientific article published on 12 July 2018

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

artículo científico publicado en 2017

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei

artículo científico publicado en 2015

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

artículo científico publicado en 2015

ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines.

artículo científico publicado en 2013

Erratum for De Rycker et al., Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

scholarly article published in Antimicrobial Agents and Chemotherapy

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

artículo científico publicado en 2016

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

artículo científico publicado en 2018

Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay

artículo científico publicado en 2019

Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.

artículo científico publicado en 2016

Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase.

artículo científico publicado en 2019

Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

scholarly article by Victoriano Corpas-Lopez et al published 12 November 2018 in ACS Infectious Diseases

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

scientific article published on 08 April 2019

Protein kinases, from B to C.

artículo científico publicado en 2007

Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration

artículo científico publicado en 2011

Setting Our Sights on Infectious Diseases

scientific article published on 06 December 2019

The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani

scientific article published on 30 January 2020

The R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis

artículo científico publicado en 2013

Trypanosoma cruzi Phosphomannomutase and Guanosine Diphosphate-Mannose Pyrophosphorylase Ligandability Assessment

artículo científico publicado en 2019

Lista de obras de Manu De Rycker

2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease

A high-content, cell-based screen identifies micropolyin, a new inhibitor of microtubule dynamics

A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

Author Correction: Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.

Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines.

Erratum for De Rycker et al., Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay

Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.

Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase.

Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Protein kinases, from B to C.

Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration

Setting Our Sights on Infectious Diseases

The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani

The R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis

Trypanosoma cruzi Phosphomannomutase and Guanosine Diphosphate-Mannose Pyrophosphorylase Ligandability Assessment