Lista de obras - Beatriz Mothe - Dominio Público Uruguay

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

artículo científico publicado en 2015

A case of hyper-reactive malarial splenomegaly. The role of rapid antigen-detecting and PCR-based tests.

artículo científico publicado en 2007

A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

artículo científico publicado en 2015

A minimal T-cell immunogen designed to cover HIV-1 specificities associated with control is immunogenic in mice and breaks CTL immunodominance

artículo científico publicado en 2012

Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques

artículo científico publicado en 2014

Alternative effector-function profiling identifies broad HIV-specific T-cell responses in highly HIV-exposed individuals who remain uninfected

artículo científico publicado en 2014

Antigen Production After Latency Reversal and Expression of Inhibitory Receptors in CD8+ T Cells Limit the Killing of HIV-1 Reactivated Cells

article

Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro.

artículo científico publicado en 2017

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control

artículo científico publicado en 2012

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

artículo científico publicado en 2014

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

artículo científico publicado en 2009

DNA vaccines expressing conserved elements provide potent and broad immune responses

artículo científico publicado en 2012

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells

artículo científico publicado en 2015

Definition of the viral targets of protective HIV-1-specific T cell responses

artículo científico publicado en 2011

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B27:05- and -B27:02-Mediated Control of HIV-1 Infection

artículo científico publicado en 2017

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints

artículo científico publicado en 2014

Differential prevalence of the HLA-C −35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals

article

Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells

artículo científico publicado en 2014

Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals

scientific article published on 27 January 2014

Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome

artículo científico publicado en 2022

Expanded Epitope Recognition by Vaccination with DNA Encoding Novel Immunogens Comprising HIV Conserved Elements

article

Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions

artículo científico publicado en 2013

Gut Microbiota Linked to Sexual Preference and HIV Infection.

artículo científico publicado en 2016

HIV T-Cell Vaccines

artículo científico publicado en 2018

HIV-1 infection in subjects older than 70: a multicenter cross-sectional assessment in Catalonia, Spain

artículo científico publicado en 2009

HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice

artículo científico publicado en 2013

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control

artículo científico publicado en 2011

Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control

artículo científico publicado en 2017

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

artículo científico publicado en 2015

Increased expression of SAMHD1 in a subset of HIV-1 elite controllers

artículo científico publicado en 2014

Influenza, but not HIV-specific CTL epitopes, elicits delayed-type hypersensitivity (DTH) reactions in HIV-infected patients

article

Large-scale screening of circulating microRNAs in individuals with HIV-1 mono-infections reveals specific liver damage signatures

article

Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

article

Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller

artículo científico publicado en 2012

Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21

artículo científico publicado en 2016

Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers

article

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

scientific article published on 06 August 2020

Modulation of antibody secreting cells and neutralizing Ab activity in HIV infected individuals undergoing structured treatment interruptions

article

Molecular characterization of heterologous HIV-1gp120 gene expression disruption in mycobacterium bovis BCG host strain: a critical issue for engineering mycobacterial based-vaccine vectors

artículo científico publicado en 2010

P16-24. Crucial contribution of sub-dominant HLA-C allele restricted CTL responses to the control of HIV

article

Pathogenesis and treatment of HIV infection: the cellular, the immune system and the neuroendocrine systems perspective

artículo científico publicado en 2013

Phase I clinical trial of an intranodally administered mRNA based therapeutic vaccine against HIV-1 infection

article

Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix).

artículo científico publicado en 2016

Psychological stress is associated with high levels of IL-6 in HIV-1 infected individuals on effective combined antiretroviral treatment

artículo científico publicado en 2012

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

artículo científico publicado en 2015

Small steps forward for HIV vaccine development

artículo científico publicado en 2020

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

scientific article published on 01 May 2019

Therapeutic Vaccine in Chronically HIV-1-Infected Patients: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Trial with HTI-TriMix

scientific article published on 06 December 2019

Treatment simplification to once daily darunavir/ritonavir guided by the darunavir inhibitory quotient in heavily pretreated HIV-infected patients.

artículo científico publicado en 2010

Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individuals

artículo científico publicado en 2013

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

artículo científico publicado en 2017

Virological, immune and host genetics markers in the control of HIV infection

artículo científico publicado en 2009

Lista de obras de Beatriz Mothe

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

A case of hyper-reactive malarial splenomegaly. The role of rapid antigen-detecting and PCR-based tests.

A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

A minimal T-cell immunogen designed to cover HIV-1 specificities associated with control is immunogenic in mice and breaks CTL immunodominance

Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques

Alternative effector-function profiling identifies broad HIV-specific T-cell responses in highly HIV-exposed individuals who remain uninfected

Antigen Production After Latency Reversal and Expression of Inhibitory Receptors in CD8+ T Cells Limit the Killing of HIV-1 Reactivated Cells

Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro.

CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

DNA vaccines expressing conserved elements provide potent and broad immune responses

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells

Definition of the viral targets of protective HIV-1-specific T cell responses

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints

Differential prevalence of the HLA-C −35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals

Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells

Effect of maraviroc intensification on HIV-1-specific T cell immunity in recently HIV-1-infected individuals

Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome

Expanded Epitope Recognition by Vaccination with DNA Encoding Novel Immunogens Comprising HIV Conserved Elements

Expansion of antibody secreting cells and modulation of neutralizing antibody activity in HIV infected individuals undergoing structured treatment interruptions

Gut Microbiota Linked to Sexual Preference and HIV Infection.

HIV T-Cell Vaccines

HIV-1 infection in subjects older than 70: a multicenter cross-sectional assessment in Catalonia, Spain

HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control

Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

Increased expression of SAMHD1 in a subset of HIV-1 elite controllers

Influenza, but not HIV-specific CTL epitopes, elicits delayed-type hypersensitivity (DTH) reactions in HIV-infected patients

Large-scale screening of circulating microRNAs in individuals with HIV-1 mono-infections reveals specific liver damage signatures

Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller

Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21

Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Modulation of antibody secreting cells and neutralizing Ab activity in HIV infected individuals undergoing structured treatment interruptions

Molecular characterization of heterologous HIV-1gp120 gene expression disruption in mycobacterium bovis BCG host strain: a critical issue for engineering mycobacterial based-vaccine vectors

P16-24. Crucial contribution of sub-dominant HLA-C allele restricted CTL responses to the control of HIV

Pathogenesis and treatment of HIV infection: the cellular, the immune system and the neuroendocrine systems perspective

Phase I clinical trial of an intranodally administered mRNA based therapeutic vaccine against HIV-1 infection

Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix).

Psychological stress is associated with high levels of IL-6 in HIV-1 infected individuals on effective combined antiretroviral treatment

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

Small steps forward for HIV vaccine development

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

Therapeutic Vaccine in Chronically HIV-1-Infected Patients: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Trial with HTI-TriMix

Treatment simplification to once daily darunavir/ritonavir guided by the darunavir inhibitory quotient in heavily pretreated HIV-infected patients.

Use of RT-defective HIV virions: new tool to evaluate specific response in chronic asymptomatic HIV-infected individuals

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

Virological, immune and host genetics markers in the control of HIV infection

Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B27:05- and -B27:02-Mediated Control of HIV-1 Infection