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Lista de obras de Rachel L Graham

A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease ⬇️

artículo científico publicado en 2012

A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant

artículo científico publicado en 2014

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

artículo científico publicado en 2018

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus

scientific article (preprint)

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

scientific article published on 06 April 2020

Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing

artículo científico publicado en 2007

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

artículo científico publicado en 2019

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

artículo científico publicado en 2017

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

artículo científico publicado en 2013

Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication

artículo científico publicado en 2004

Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines

scholarly article by Vineet D. Menachery published in September 2018

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

scholarly article published 28 April 2018

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

artículo científico publicado en 2018

Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity

artículo científico publicado en 2011

Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses

artículo científico publicado en 2013

Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

artículo científico publicado en 2010

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

artículo científico

MERS-CoV NSP16 necessary for IFN resistance and viral pathogenesis

MHV-A59 ORF1a replicase protein nsp7-nsp10 processing in replication

artículo científico publicado en 2006

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

artículo científico publicado en 2017

Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis

artículo científico publicado en 2007

Novel modulators of p53-signaling encoded by unknown genes of emerging viruses

artículo científico publicado en 2021

Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication

artículo científico publicado en 2007

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

scientific article published on 07 July 2020

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

artículo científico publicado en 2020

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

artículo científico publicado en 2020

Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice

artículo científico publicado en 2005

Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

artículo científico publicado en 2008

The nsp2 proteins of mouse hepatitis virus and SARS coronavirus are dispensable for viral replication

artículo científico publicado en 2006

The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication

artículo científico publicado en 2005

Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection

artículo científico publicado en 2020

Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

artículo científico publicado en 2019

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