Lista de obras - Daniela Montesarchio - Dominio Público Uruguay

5‘-Modified G-Quadruplex Forming Oligonucleotides Endowed with Anti-HIV Activity: Synthesis and Biophysical Properties

article

A first-in-class and a fished out anticancer platinum compound: cis-[PtCl2(NH3)2] and cis-[PtI2(NH3)2] compared for their reactivity towards DNA model systems

artículo científico publicado en 2016

A new competitive fluorescence assay for the detection of patulin toxin

scientific article published on 01 January 2007

A new design for nucleolipid-based Ru(III) complexes as anticancer agents

artículo científico publicado en 2013

A new solid-phase synthesis of oligonucleotides 3'-conjugated with peptides

scientific article published on 01 February 1999

An efficient and versatile solid-phase synthesis of 5'- and 3'-conjugated oligonucleotides

artículo científico publicado en 2005

An efficient solid phase synthesis of 5'-phosphodiester and phosphoramidate monoester nucleoside analogues.

artículo científico publicado en 2005

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies.

artículo científico publicado en 2013

Anti-HIV activity of new higher order G-quadruplex aptamers obtained from tetra-end-linked oligonucleotides.

artículo científico publicado en 2018

Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics

artículo científico publicado en 2020

Anticancer Ruthenium(III) Complexes and Ru(III)-Containing Nanoformulations: An Update on the Mechanism of Action and Biological Activity

scientific article published on 26 September 2019

Anticancer cationic ruthenium nanovectors: from rational molecular design to cellular uptake and bioactivity.

artículo científico publicado en 2013

Antiproliferative effects of ruthenium-based nucleolipidic nanoaggregates in human models of breast cancer in vitro: insights into their mode of action.

scientific article published on 28 March 2017

Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase.

artículo científico publicado en 2017

Automated solid phase synthesis of cyclic oligonucleotides: a further improvement

artículo científico publicado en 1995

Benzodifuran Derivatives as Potential Antiproliferative Agents: Possible Correlation between Their Bioactivity and Aggregation Properties

artículo científico publicado en 2016

Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound

scientific article published on 25 February 2019

Breast Cancer Chemotherapeutic Options: A General Overview on the Preclinical Validation of a Multi-Target Ruthenium(III) Complex Lodged in Nucleolipid Nanosystems

artículo científico publicado en 2020

Carbohydrate-based synthetic ion transporters.

artículo científico publicado en 2012

Cholesterol-Based Nucleolipid-Ruthenium Complex Stabilized by Lipid Aggregates for Antineoplastic Therapy ⬇️

artículo científico publicado el 21 de marzo de 2012

Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands

artículo científico publicado en 2018

Cyclic Phosphate-Linked Oligosaccharides: Synthesis and Conformational Behavior of Novel Cyclic Oligosaccharide Analogues

artículo científico publicado en 2006

Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight

artículo científico publicado en 2020

Design, synthesis and characterisation of guanosine-based amphiphiles.

artículo científico publicado en 2011

Developing functionalized Fe3O4–Au nanoparticles: a physico-chemical insight

artículo científico publicado en 2015

Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition

artículo científico publicado en 2020

Discovery of novel anti-HIV active G-quadruplex-forming oligonucleotides.

artículo científico publicado en 2010

Effect of lengthening of peptide backbone by insertion of chiral beta-homo amino acid residues: conformational behavior of linear peptides containing alternating L-leucine and beta-homo L-leucine residues

artículo científico publicado en 2000

Elucidating the reactivity of Pt(II) complexes with (O,S) bidentate ligands towards DNA model systems.

artículo científico publicado en 2016

Exploring cellular uptake, accumulation and mechanism of action of a cationic Ru-based nanosystem in human preclinical models of breast cancer

artículo científico publicado en 2019

Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics.

artículo científico publicado en 2017

Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.

artículo científico

Fluorescent thrombin binding aptamer-tagged nanoparticles for an efficient and reversible control of thrombin activity

artículo científico publicado en 2017

G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents

artículo científico publicado en 2015

G-Quadruplex on Oligo Affinity Support (G4-OAS): An Easy Affinity Chromatography-Based Assay for the Screening of G-Quadruplex Ligands

artículo científico publicado en 2014

G-quadruplex nucleic acids.

artículo científico publicado en 2010

G-quadruplex-based aptamers against protein targets in therapy and diagnostics.

artículo científico publicado en 2016

Guanine-based amphiphiles: synthesis, ion transport properties and biological activity.

artículo científico publicado en 2015

Huntingtin protein: A new option for fixing the Huntington's disease countdown clock.

artículo científico publicado en 2018

Insights into the G-rich VEGF-binding aptamer V7t1: when two G-quadruplexes are better than one!

scientific article published on 01 September 2019

Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems.

artículo científico publicado en 2015

Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu

artículo científico publicado en 2013

Ion Transport through Lipid Bilayers by Synthetic Ionophores: Modulation of Activity and Selectivity ⬇️

artículo científico publicado el 27 de marzo de 2013

Ionophores at work: Exploring the interaction of guanosine-based amphiphiles with phospholipid membranes.

artículo científico publicado en 2017

N(3)-protection of thymidine with Boc for an easy synthetic access to sugar-alkylated nucleoside analogs

artículo científico publicado en 2012

Nanostructuring of CyPLOS (Cyclic Phosphate-Linked OligoSaccharides), novel saccharide-based synthetic ion transporters

artículo científico publicado en 2010

New solid supports linking nucleoside scaffolds.

artículo científico publicado en 2003

Not unusual, just different! Chemistry, biology and applications of G-quadruplex nucleic acids

artículo científico publicado en 2017

Novel amphiphilic cyclic oligosaccharides: synthesis and self-aggregation properties.

artículo científico publicado en 2007

Nucleolipid nanovectors as molecular carriers for potential applications in drug delivery.

artículo científico publicado en 2011

Oligonucleotides containing a lysine residue as 3'-3' junction for alternate strand triple helix formation.

artículo científico publicado en 2001

On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight

artículo científico publicado en 2020

On the mechanism of ion transport through lipid membranes mediated by PEGylated cyclic oligosaccharides (CyPLOS): an ESR study.

artículo científico publicado en 2013

On the pH-Modulated Ru-Based Prodrug Activation Mechanism

scientific article published on 07 January 2019

Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: defining the structure and probing in vivo applications.

artículo científico publicado en 2016

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer.

artículo científico publicado en 2012

Ruthenium-based complex nanocarriers for cancer therapy.

artículo científico publicado en 2012

Solid-phase synthesis of cyclic PNA and PNA-DNA chimeras

artículo científico publicado en 2006

Stability Is Not Everything: The Case of the Cyclisation of a Thrombin-Binding Aptamer

artículo científico publicado en 2019

Synthesis and DNA binding properties of DNA-PNA chimeras.

artículo científico

Synthesis and biophysical characterization of G-rich oligonucleotides conjugated with sugar-phosphate tails.

artículo científico publicado en 2007

Synthesis and preliminary biological evaluation of a new pyridocarbazole derivative covalently linked to a thymidine nucleoside as a potential targeted antitumoral agent. I.

artículo científico publicado en 2003

Synthesis of a cholesteryl-HEG phosphoramidite derivative and its application to lipid-conjugates of the anti-HIV 5'TGGGAG³' Hotoda's sequence.

artículo científico publicado en 2012

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

artículo científico publicado en 2020

Synthesis, biophysical characterization, and anti-HIV activity of glyco-conjugated G-quadruplex-forming oligonucleotides.

artículo científico publicado en 2008

Synthesis, self-aggregation and bioactivity properties of a cationic aminoacyl surfactant, based on a new class of highly functionalized nucleolipids.

artículo científico publicado en 2012

Tailoring a lead-like compound targeting multiple G-quadruplex structures

scientific article published on 27 November 2018

Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.

artículo científico publicado en 2017

Targeting duplex DNA with DNA-PNA chimeras? Physico-chemical characterization of a triplex DNA-PNA/DNA/DNA.

artículo científico

The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition

scientific article published on 22 April 2019

Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography

scientific article published on 13 March 2020

Tuning the Polymorphism of the Anti-VEGF G-rich V7t1 Aptamer by Covalent Dimeric Constructs

scientific article published on 13 March 2020

“Dressing up” an Old Drug: An Aminoacyl Lipid for the Functionalization of Ru(III)-Based Anticancer Agents

artículo científico publicado en 2017

Lista de obras de Daniela Montesarchio

5‘-Modified G-Quadruplex Forming Oligonucleotides Endowed with Anti-HIV Activity: Synthesis and Biophysical Properties

A first-in-class and a fished out anticancer platinum compound: cis-[PtCl2(NH3)2] and cis-[PtI2(NH3)2] compared for their reactivity towards DNA model systems

A new competitive fluorescence assay for the detection of patulin toxin

A new design for nucleolipid-based Ru(III) complexes as anticancer agents

A new solid-phase synthesis of oligonucleotides 3'-conjugated with peptides

An efficient and versatile solid-phase synthesis of 5'- and 3'-conjugated oligonucleotides

An efficient solid phase synthesis of 5'-phosphodiester and phosphoramidate monoester nucleoside analogues.

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies.

Anti-HIV activity of new higher order G-quadruplex aptamers obtained from tetra-end-linked oligonucleotides.

Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics

Anticancer Ruthenium(III) Complexes and Ru(III)-Containing Nanoformulations: An Update on the Mechanism of Action and Biological Activity

Anticancer cationic ruthenium nanovectors: from rational molecular design to cellular uptake and bioactivity.

Antiproliferative effects of ruthenium-based nucleolipidic nanoaggregates in human models of breast cancer in vitro: insights into their mode of action.

Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase.

Automated solid phase synthesis of cyclic oligonucleotides: a further improvement

Benzodifuran Derivatives as Potential Antiproliferative Agents: Possible Correlation between Their Bioactivity and Aggregation Properties

Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound

Breast Cancer Chemotherapeutic Options: A General Overview on the Preclinical Validation of a Multi-Target Ruthenium(III) Complex Lodged in Nucleolipid Nanosystems

Carbohydrate-based synthetic ion transporters.

Cholesterol-Based Nucleolipid-Ruthenium Complex Stabilized by Lipid Aggregates for Antineoplastic Therapy ⬇️

Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands

Cyclic Phosphate-Linked Oligosaccharides: Synthesis and Conformational Behavior of Novel Cyclic Oligosaccharide Analogues

Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight

Design, synthesis and characterisation of guanosine-based amphiphiles.

Developing functionalized Fe3O4–Au nanoparticles: a physico-chemical insight

Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition

Discovery of novel anti-HIV active G-quadruplex-forming oligonucleotides.

Effect of lengthening of peptide backbone by insertion of chiral beta-homo amino acid residues: conformational behavior of linear peptides containing alternating L-leucine and beta-homo L-leucine residues

Elucidating the reactivity of Pt(II) complexes with (O,S) bidentate ligands towards DNA model systems.

Exploring cellular uptake, accumulation and mechanism of action of a cationic Ru-based nanosystem in human preclinical models of breast cancer

Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics.

Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.

Fluorescent thrombin binding aptamer-tagged nanoparticles for an efficient and reversible control of thrombin activity

G-Quadruplex Forming Oligonucleotides as Anti-HIV Agents

G-Quadruplex on Oligo Affinity Support (G4-OAS): An Easy Affinity Chromatography-Based Assay for the Screening of G-Quadruplex Ligands

G-quadruplex nucleic acids.

G-quadruplex-based aptamers against protein targets in therapy and diagnostics.

Guanine-based amphiphiles: synthesis, ion transport properties and biological activity.

Huntingtin protein: A new option for fixing the Huntington's disease countdown clock.

Insights into the G-rich VEGF-binding aptamer V7t1: when two G-quadruplexes are better than one!

Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems.

Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu

Ion Transport through Lipid Bilayers by Synthetic Ionophores: Modulation of Activity and Selectivity ⬇️

Ionophores at work: Exploring the interaction of guanosine-based amphiphiles with phospholipid membranes.

N(3)-protection of thymidine with Boc for an easy synthetic access to sugar-alkylated nucleoside analogs

Nanostructuring of CyPLOS (Cyclic Phosphate-Linked OligoSaccharides), novel saccharide-based synthetic ion transporters

New solid supports linking nucleoside scaffolds.

Not unusual, just different! Chemistry, biology and applications of G-quadruplex nucleic acids

Novel amphiphilic cyclic oligosaccharides: synthesis and self-aggregation properties.

Nucleolipid nanovectors as molecular carriers for potential applications in drug delivery.

Oligonucleotides containing a lysine residue as 3'-3' junction for alternate strand triple helix formation.

On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight

On the mechanism of ion transport through lipid membranes mediated by PEGylated cyclic oligosaccharides (CyPLOS): an ESR study.

On the pH-Modulated Ru-Based Prodrug Activation Mechanism

Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: defining the structure and probing in vivo applications.

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer.

Ruthenium-based complex nanocarriers for cancer therapy.

Solid-phase synthesis of cyclic PNA and PNA-DNA chimeras

Stability Is Not Everything: The Case of the Cyclisation of a Thrombin-Binding Aptamer

Synthesis and DNA binding properties of DNA-PNA chimeras.

Synthesis and biophysical characterization of G-rich oligonucleotides conjugated with sugar-phosphate tails.

Synthesis and preliminary biological evaluation of a new pyridocarbazole derivative covalently linked to a thymidine nucleoside as a potential targeted antitumoral agent. I.

Synthesis of a cholesteryl-HEG phosphoramidite derivative and its application to lipid-conjugates of the anti-HIV 5'TGGGAG³' Hotoda's sequence.

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

Synthesis, biophysical characterization, and anti-HIV activity of glyco-conjugated G-quadruplex-forming oligonucleotides.

Synthesis, self-aggregation and bioactivity properties of a cationic aminoacyl surfactant, based on a new class of highly functionalized nucleolipids.

Tailoring a lead-like compound targeting multiple G-quadruplex structures

Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.

Targeting duplex DNA with DNA-PNA chimeras? Physico-chemical characterization of a triplex DNA-PNA/DNA/DNA.

The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition

Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography

Tuning the Polymorphism of the Anti-VEGF G-rich V7t1 Aptamer by Covalent Dimeric Constructs

“Dressing up” an Old Drug: An Aminoacyl Lipid for the Functionalization of Ru(III)-Based Anticancer Agents