Lista de obras - Hans-Gottfried Genieser - Dominio Público Uruguay

(Rp)- and (Sp)-8-piperidino-adenosine 3',5'-(cyclic)thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II

scientific article published on 01 May 1994

(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor.

artículo científico publicado en 1994

8-pCPT-2'-O-Me-cAMP-AM: an improved Epac-selective cAMP analogue.

artículo científico publicado en 2008

A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa

article by Juliane Düvel et al published February 2012 in Journal of Microbiological Methods

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

artículo científico publicado en 2002

Activation of PDE10 and PDE11 Phosphodiesterases ⬇️

artículo científico publicado el 21 de noviembre de 2011

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

artículo científico publicado en 2010

Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides.

artículo científico publicado en 2011

Activation of protein kinase A (PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy.

artículo científico publicado en 2004

Activation profile of cGMP-dependent protein kinase Iα

artículo científico publicado en 2013

Analysis of substrate specificity and kinetics of cyclic nucleotide phosphodiesterases with N'-methylanthraniloyl-substituted purine and pyrimidine 3',5'-cyclic nucleotides by fluorescence spectrometry

artículo científico publicado en 2013

Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs

artículo científico publicado en 2015

Binding of Regulatory Subunits of Cyclic AMP-Dependent Protein Kinase to Cyclic CMP Agarose ⬇️

artículo científico publicado el 9 de julio de 2012

Bioactivatable, Membrane-Permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells ⬇️

artículo científico publicado el 1 de septiembre de 2003

Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

artículo científico publicado en 2008

CREB phosphorylation and melatonin biosynthesis in the rat pineal gland: Involvement of cyclic AMP dependent protein kinase type II

artículo científico publicado en 1999

Chemical tools selectively target components of the PKA system

artículo científico publicado en 2009

Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.

artículo científico publicado en 2018

Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

scientific journal article

Cyclic CMP and cyclic UMP: new (old) second messengers.

artículo científico publicado en 2011

Cyclic nucleotide analogs as probes of signaling pathways.

artículo científico publicado en 2008

Cyclic nucleotides as affinity tools: phosphorothioate cAMP analogues address specific PKA subproteomes.

artículo científico publicado en 2010

DNA catabolites in triathletes: effects of supplementation with an aronia–citrus juice (polyphenols-rich juice)

artículo científico publicado en 2016

Derivatives of 1-beta-D-ribofuranosylbenzimidazole 3',5'-phosphate that mimic the actions of adenosine 3',5'-phosphate (cAMP) and guanosine 3',5'-phosphate (cGMP)

scientific article published on 01 October 1992

Effect of cGMP analogues and protein kinase G blocker on secretory activity, apoptosis and the cAMP/protein kinase A system in porcine ovarian granulosa cells in vitro

artículo científico publicado en 2000

Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation

artículo científico publicado en 2015

Effect of four cGMP analogues with different mechanisms of action on hormone release by porcine ovarian granulosa cells in vitro.

artículo científico publicado en 2000

Effect of restricted food intake on production, catabolism, and effects of IGF-I and cyclic nucleotides in cultured ovarian tissue of domestic nutria (Myocastor coypus).

artículo científico publicado en 2000

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

artículo científico publicado en 2003

Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac.

artículo científico publicado en 2010

Fast-atom bombardment tandem mass spectrometry of cyclic nucleotide analogues used as site-selective activators of cyclic nucleotide-dependent protein kinases

artículo científico publicado en 1998

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM.

artículo científico publicado en 2009

Kinetics and nucleotide specificity of a surface cAMP binding site in , which is not down-regulated by cAMP

artículo científico publicado en 1991

Mapping of the epitope/paratope interactions of a monoclonal antibody directed against adenosine 3',5'-monophosphate ⬇️

artículo científico publicado el 1 de julio de 1992

Medicinal Chemistry of the Noncanonical Cyclic Nucleotides cCMP and cUMP.

artículo científico publicado en 2016

Melatonin and hydroxytyrosol-rich wines influence the generation of DNA oxidation catabolites linked to mutagenesis after the ingestion of three types of wine by healthy volunteers.

artículo científico publicado en 2016

Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility.

artículo científico publicado en 1994

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.

artículo científico publicado en 2011

New cGMP analogues restrain proliferation and migration of melanoma cells.

artículo científico publicado en 2017

New dimeric cGMP analogues reduce proliferation in three colon cancer cell lines

artículo científico publicado en 2017

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans ⬇️

artículo científico publicado el 1 de mayo de 2011

Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine.

artículo científico publicado en 1993

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates.

artículo científico publicado en 1990

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides ⬇️

artículo científico publicado el 29 de junio de 2011

Quantification of cAMP and cGMP analogs in intact cells: pitfals in enzyme immunoassays for cyclic nucleotides.

artículo científico publicado en 2011

Regulation of olfactory signalling via cGMP-dependent protein kinase

artículo científico publicado en 1996

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes

scientific journal article

Starfish oocyte maturation: evidence for a cyclic AMP-dependent inhibitory pathway

artículo científico publicado en 1989

Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.

artículo científico publicado en 2013

Structure-guided design of selective Epac1 and Epac2 agonists

artículo científico publicado en 2015

Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel ⬇️

artículo científico publicado el 1 de febrero de 1998

Systematic interpretation of cyclic nucleotide binding studies using KinetXBase

artículo científico publicado en 2008

The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs.

artículo científico publicado en 2016

Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells ⬇️

artículo científico publicado el 1 de mayo de 1992

cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression.

artículo científico publicado en 2008

Lista de obras de Hans-Gottfried Genieser

(Rp)- and (Sp)-8-piperidino-adenosine 3',5'-(cyclic)thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II

(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor.

8-pCPT-2'-O-Me-cAMP-AM: an improved Epac-selective cAMP analogue.

A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

Activation of PDE10 and PDE11 Phosphodiesterases ⬇️

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

Activation of cGMP-dependent protein kinase Iα and cAMP-dependent protein kinase A isoforms by cyclic nucleotides.

Activation of protein kinase A (PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy.

Activation profile of cGMP-dependent protein kinase Iα

Analysis of substrate specificity and kinetics of cyclic nucleotide phosphodiesterases with N'-methylanthraniloyl-substituted purine and pyrimidine 3',5'-cyclic nucleotides by fluorescence spectrometry

Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs

Binding of Regulatory Subunits of Cyclic AMP-Dependent Protein Kinase to Cyclic CMP Agarose ⬇️

Bioactivatable, Membrane-Permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells ⬇️

Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

CREB phosphorylation and melatonin biosynthesis in the rat pineal gland: Involvement of cyclic AMP dependent protein kinase type II

Chemical tools selectively target components of the PKA system

Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.

Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription

Cyclic CMP and cyclic UMP: new (old) second messengers.

Cyclic nucleotide analogs as probes of signaling pathways.

Cyclic nucleotides as affinity tools: phosphorothioate cAMP analogues address specific PKA subproteomes.

DNA catabolites in triathletes: effects of supplementation with an aronia–citrus juice (polyphenols-rich juice)

Derivatives of 1-beta-D-ribofuranosylbenzimidazole 3',5'-phosphate that mimic the actions of adenosine 3',5'-phosphate (cAMP) and guanosine 3',5'-phosphate (cGMP)

Effect of cGMP analogues and protein kinase G blocker on secretory activity, apoptosis and the cAMP/protein kinase A system in porcine ovarian granulosa cells in vitro

Effect of elite physical exercise by triathletes on seven catabolites of DNA oxidation

Effect of four cGMP analogues with different mechanisms of action on hormone release by porcine ovarian granulosa cells in vitro.

Effect of restricted food intake on production, catabolism, and effects of IGF-I and cyclic nucleotides in cultured ovarian tissue of domestic nutria (Myocastor coypus).

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac.

Fast-atom bombardment tandem mass spectrometry of cyclic nucleotide analogues used as site-selective activators of cyclic nucleotide-dependent protein kinases

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM.

Kinetics and nucleotide specificity of a surface cAMP binding site in , which is not down-regulated by cAMP

Mapping of the epitope/paratope interactions of a monoclonal antibody directed against adenosine 3',5'-monophosphate ⬇️

Medicinal Chemistry of the Noncanonical Cyclic Nucleotides cCMP and cUMP.

Melatonin and hydroxytyrosol-rich wines influence the generation of DNA oxidation catabolites linked to mutagenesis after the ingestion of three types of wine by healthy volunteers.

Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility.

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.

New cGMP analogues restrain proliferation and migration of melanoma cells.

New dimeric cGMP analogues reduce proliferation in three colon cancer cell lines

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans ⬇️

Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate (Rp-cAMPS) can contain biologically active amounts of adenosine.

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates.

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides ⬇️

Quantification of cAMP and cGMP analogs in intact cells: pitfals in enzyme immunoassays for cyclic nucleotides.

Regulation of olfactory signalling via cGMP-dependent protein kinase

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes

Starfish oocyte maturation: evidence for a cyclic AMP-dependent inhibitory pathway

Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.

Structure-guided design of selective Epac1 and Epac2 agonists

Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel ⬇️

Systematic interpretation of cyclic nucleotide binding studies using KinetXBase

The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs.

Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells ⬇️

cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression.