Lista de obras - Annabelle Lewis - Dominio Público Uruguay

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

artículo científico publicado en 2013

A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA

scientific journal article

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding

artículo científico publicado en 2014

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

artículo científico publicado en 2014

Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer.

artículo científico publicado en 2017

Chromosome loops, insulators, and histone methylation: new insights into regulation of imprinting in clusters.

artículo científico publicado en 2004

Co-evolution of X-chromosome inactivation and imprinting in mammals

artículo científico publicado en 2005

Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo

artículo científico publicado en 2006

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions

artículo científico publicado en 2003

Epigenetics and imprinting of the trophoblast -- a workshop report.

artículo científico publicado en 2006

Erratum to “Epigenetics and Imprinting of the Trophoblast – A Workshop Report” [Placenta 27, supplement A, Trophoblast Research, Vol. 20 S122–S126]

scholarly article published in Placenta

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

artículo científico publicado en 2011

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

scientific journal article

Five endometrial cancer risk loci identified through genome-wide association analysis

artículo científico publicado en 2016

Genomic imprinting: CTCF protects the boundaries

artículo científico publicado en 2004

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1.

artículo científico publicado en 2012

How imprinting centres work

artículo científico publicado en 2006

Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.

artículo científico publicado en 2004

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

artículo científico publicado en 2014

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

artículo científico publicado en 2011

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

artículo científico publicado en 2017

Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.

artículo científico publicado en 2010

Tandem repeat hypothesis in imprinting: deletion of a conserved direct repeat element upstream of H19 has no effect on imprinting in the Igf2-H19 region

artículo científico publicado en 2004

The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression

artículo científico publicado en 2009

The C-terminus of Apc does not influence intestinal adenoma development or progression

artículo científico publicado en 2011

The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability

artículo científico publicado en 2020

The Utility of Mouse Models in Post-GWAS Research ⬇️

artículo científico publicado el 7 de diciembre de 2012

The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing

scientific article published on 14 January 2009

Lista de obras de Annabelle Lewis

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer.

Chromosome loops, insulators, and histone methylation: new insights into regulation of imprinting in clusters.

Co-evolution of X-chromosome inactivation and imprinting in mammals

Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions

Epigenetics and imprinting of the trophoblast -- a workshop report.

Erratum to “Epigenetics and Imprinting of the Trophoblast – A Workshop Report” [Placenta 27, supplement A, Trophoblast Research, Vol. 20 S122–S126]

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development

Five endometrial cancer risk loci identified through genome-wide association analysis

Genomic imprinting: CTCF protects the boundaries

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1.

How imprinting centres work

Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.

Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.

Tandem repeat hypothesis in imprinting: deletion of a conserved direct repeat element upstream of H19 has no effect on imprinting in the Igf2-H19 region

The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression

The C-terminus of Apc does not influence intestinal adenoma development or progression

The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability

The Utility of Mouse Models in Post-GWAS Research ⬇️

The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing