Lista de obras - E Mellado - Dominio Público Uruguay

A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatus

scientific article published on 26 November 2020

A New Aspergillus fumigatus Typing Method Based on Hypervariable Tandem Repeats Located within Exons of Surface Protein Coding Genes (TRESP).

artículo científico publicado en 2016

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

artículo científico publicado en 2007

A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin

artículo científico publicado en 2012

A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigatus.

artículo científico publicado en 2011

Activity profile in vitro of micafungin against Spanish clinical isolates of common and emerging species of yeasts and molds.

artículo científico publicado en 2009

An alternative host model of a mixed fungal infection by azole susceptible and resistant Aspergillus spp strains

artículo científico publicado en 2015

An invertebrate model to evaluate virulence in Aspergillus fumigatus: the role of azole resistance.

artículo científico publicado en 2014

Antifungal susceptibility profile of clinical Alternaria spp. identified by molecular methods

article

Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods.

artículo científico publicado en 2008

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?

scientific article published in 2021

Aspergillus fumigatus C-5 sterol desaturases Erg3A and Erg3B: role in sterol biosynthesis and antifungal drug susceptibility.

artículo científico publicado en 2006

Aspergillus fumigatus cyp51A polymorphisms, an insight on their significance.

artículo científico publicado en 2018

Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance.

artículo científico publicado en 2011

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

artículo científico publicado en 2009

Blood and tissue distribution of posaconazole in a rat model of invasive pulmonary aspergillosis

artículo científico publicado en 2016

Breakthrough pulmonary Aspergillus fumigatus infection with multiple triazole resistance in a Spanish patient with chronic myeloid leukemia ⬇️

artículo científico publicado el 15 de septiembre de 2012

COVID-19 Associated Pulmonary Aspergillosis (CAPA): Hospital or Home Environment as a Source of Life-Threatening Aspergillus fumigatus Infection?

scientific article published in 2022

Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis virulence in the non-conventional host Galleria mellonella

artículo científico publicado en 2013

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.

scientific article published on 22 July 2013

Characterization of Aspergillus fumigatus cross-resistance between clinical and DMI azole drugs

artículo científico publicado en 2020

Clinical relevance of resistance to antifungals.

artículo científico publicado en 2008

Comparison of Two Highly Discriminatory Typing Methods to Analyze Azole Resistance

scientific article published on 20 July 2018

Corrigendum to "First detection of Aspergillus fumigatus azole resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain" [New Microbes New Infect 6 (2015) 33-34].

artículo científico publicado en 2016

Could the determination of Aspergillus fumigatus mating type have prognostic value in invasive aspergillosis?

artículo científico publicado en 2017

Current status of antifungal resistance and its impact on clinical practice.

artículo científico

Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion

artículo científico publicado en 2014

Detection of Aspergillus spp. by real-time PCR in a murine model of pulmonary infection

artículo científico publicado en 2005

Development and validation of a High Resolution Melting Assay to detect azole resistance in Aspergillus fumigatus

artículo científico publicado en 2017

Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

artículo científico publicado en 2008

Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

artículo científico publicado en 2010

Epidemiological cutoffs and cross-resistance to azole drugs in Aspergillus fumigatus.

artículo científico publicado en 2008

Ergosterol biosynthesis in Aspergillus fumigatus: its relevance as an antifungal target and role in antifungal drug resistance.

artículo científico publicado en 2012

Ergosterol biosynthesis pathway in Aspergillus fumigatus.

artículo científico publicado en 2007

First detection of Aspergillus fumigatus azole-resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain

artículo científico publicado en 2015

Fitness Studies of Azole-Resistant Strains of Aspergillus fumigatus.

artículo científico publicado en 2015

Frequency of voriconazole resistance in vitro among Spanish clinical isolates of Candida spp. According to breakpoints established by the Antifungal Subcommittee of the European Committee on Antimicrobial Susceptibility Testing.

artículo científico publicado en 2011

Functional analysis of the fungal/plant class chitinase family in Aspergillus fumigatus

article

Galactomannan enzyme immunoassay and quantitative Real Time PCR as tools to evaluate the exposure and response in a rat model of aspergillosis after posaconazole prophylaxis

artículo científico publicado en 2016

Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species

artículo científico publicado en 2014

Genome-Wide Comparative Analysis of Aspergillus fumigatus Strains: The Reference Genome as a Matter of Concern

artículo científico publicado en 2018

Genotype distribution of clinical isolates of Trichosporon asahii based on sequencing of intergenic spacer 1.

artículo científico publicado en 2007

Halophilic bacteria as a source of novel hydrolytic enzymes

artículo científico publicado en 2013

Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi.

artículo científico publicado en 2006

Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010). ⬇️

artículo científico publicado en 2015

Hospital Environment as a Source of Azole-Resistant Aspergillus fumigatus Strains with TR34/L98H and G448S Cyp51A Mutations

artículo científico publicado en 2021

In Vitro Activities of Three Licensed Antifungal Agents against Spanish Clinical Isolates of Aspergillus spp ⬇️

artículo científico publicado el 1 de octubre de 2003

In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis.

artículo científico publicado en 2006

In vitro activity of antifungals against Zygomycetes.

scientific article published on October 2009

In vitro activity of ravuconazole against 923 clinical isolates of nondermatophyte filamentous fungi.

artículo científico publicado en 2005

In vivo efficacy of voriconazole and posaconazole therapy in a novel invertebrate model of Aspergillus fumigatus infection

artículo científico publicado en 2015

Interlaboratory reproducibility of a microsatellite-based typing assay for Aspergillus fumigatus through the use of allelic ladders: proof of concept

artículo científico publicado en 2009

Interlaboratory reproducibility of a single-locus sequence-based method for strain typing of Aspergillus fumigatus

artículo científico publicado en 2009

Invasive aspergillosis caused by cryptic Aspergillus species: a report of two consecutive episodes in a patient with leukaemia.

artículo científico publicado en 2012

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for fast and accurate identification of clinically relevant Aspergillus species.

artículo científico publicado en 2011

Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability

artículo científico publicado en 2010

Molecular identification, antifungal resistance and virulence of Cryptococcus neoformans and Cryptococcus deneoformans isolated in Seville, Spain.

artículo científico publicado en 2016

Multiple-Triazole–Resistant Aspergillosis

artículo científico publicado en 2007

New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growth

artículo científico publicado en 2016

Point Mutations in the 14-α Sterol Demethylase Cyp51A or Cyp51C Could Contribute to Azole Resistance in Aspergillus flavus

artículo científico publicado en 2020

Polyphasic characterization of fungal isolates from a published case of invasive aspergillosis reveals misidentification of Aspergillus felis as Aspergillus viridinutans

artículo científico publicado en 2014

Population-Based Survey of Filamentous Fungi and Antifungal Resistance in Spain (FILPOP Study).

artículo científico publicado en 2013

Population-based survey of filamentous fungi and antifungal resistance in Spain (FILPOP Study).

artículo científico publicado en 2013

Proposal for a unified nomenclature for target-site mutations associated with resistance to fungicides

artículo científico publicado en 2016

Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus.

artículo científico publicado en 2015

Pulmonary mycetoma caused by an atypical isolate of Paecilomyces species in an immunocompetent individual: case report and literature review of Paecilomyces lung infections.

artículo científico publicado en 2005

Rapid development of Candida krusei echinocandin resistance during caspofungin therapy

artículo científico publicado en 2015

Resistance to voriconazole due to a G448S substitution in Aspergillus fumigatus in a patient with cerebral aspergillosis

artículo científico publicado en 2012

Ribosomic DNA intergenic spacer 1 region is useful when identifying Candida parapsilosis spp. complex based on high-resolution melting analysis.

artículo científico publicado en 2014

Role of Aspergillus lentulus 14-α sterol demethylase (Cyp51A) in azole drug susceptibility.

artículo científico publicado en 2011

Species identification and antifungal susceptibility patterns of species belonging to Aspergillus section Nigri.

artículo científico publicado en 2009

Susceptibility testing and molecular classification of Paecilomyces spp.

artículo científico publicado en 2008

The ZrfC alkaline zinc transporter is required for Aspergillus fumigatus virulence and its growth in the presence of the Zn/Mn-chelating protein calprotectin.

artículo científico publicado en 2013

The non-mammalian hostGalleria mellonellacan be used to study the virulence of the fungal pathogenCandida tropicalisand the efficacy of antifungal drugs during infection by this pathogenic yeast ⬇️

artículo científico publicado el 21 de noviembre de 2012

Triazole Resistance in Aspergillus Species: An Emerging Problem

artículo científico publicado en 2017

Triazole Resistance in Aspergillus spp.: A Worldwide Problem?

artículo científico publicado en 2016

Zygomycosis Caused by Rhizopus microsporus and Rhizopus oryzae in Madhya Pradesh (M.P.) Central India: A Report of Two Cases ⬇️

artículo científico publicado el 23 de marzo de 2012

Lista de obras de E Mellado

A Cyp51B Mutation Contributes to Azole Resistance in <i>Aspergillus fumigatus</i>

A New Aspergillus fumigatus Typing Method Based on Hypervariable Tandem Repeats Located within Exons of Surface Protein Coding Genes (TRESP).

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin

A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigatus.

Activity profile in vitro of micafungin against Spanish clinical isolates of common and emerging species of yeasts and molds.

An alternative host model of a mixed fungal infection by azole susceptible and resistant Aspergillus spp strains

An invertebrate model to evaluate virulence in Aspergillus fumigatus: the role of azole resistance.

Antifungal susceptibility profile of clinical Alternaria spp. identified by molecular methods

Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods.

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?

Aspergillus fumigatus C-5 sterol desaturases Erg3A and Erg3B: role in sterol biosynthesis and antifungal drug susceptibility.

Aspergillus fumigatus cyp51A polymorphisms, an insight on their significance.

Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance.

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

Blood and tissue distribution of posaconazole in a rat model of invasive pulmonary aspergillosis

Breakthrough pulmonary Aspergillus fumigatus infection with multiple triazole resistance in a Spanish patient with chronic myeloid leukemia ⬇️

COVID-19 Associated Pulmonary Aspergillosis (CAPA): Hospital or Home Environment as a Source of Life-Threatening Aspergillus fumigatus Infection?

Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis virulence in the non-conventional host Galleria mellonella

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.

Characterization of <i>Aspergillus fumigatus</i> cross-resistance between clinical and DMI azole drugs

Clinical relevance of resistance to antifungals.

Comparison of Two Highly Discriminatory Typing Methods to Analyze Azole Resistance

Corrigendum to "First detection of Aspergillus fumigatus azole resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain" [New Microbes New Infect 6 (2015) 33-34].

Could the determination of Aspergillus fumigatus mating type have prognostic value in invasive aspergillosis?

Current status of antifungal resistance and its impact on clinical practice.

Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion

Detection of Aspergillus spp. by real-time PCR in a murine model of pulmonary infection

Development and validation of a High Resolution Melting Assay to detect azole resistance in Aspergillus fumigatus

Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

Epidemiological cutoffs and cross-resistance to azole drugs in Aspergillus fumigatus.

Ergosterol biosynthesis in Aspergillus fumigatus: its relevance as an antifungal target and role in antifungal drug resistance.

Ergosterol biosynthesis pathway in Aspergillus fumigatus.

First detection of Aspergillus fumigatus azole-resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain

Fitness Studies of Azole-Resistant Strains of Aspergillus fumigatus.

Frequency of voriconazole resistance in vitro among Spanish clinical isolates of Candida spp. According to breakpoints established by the Antifungal Subcommittee of the European Committee on Antimicrobial Susceptibility Testing.

Functional analysis of the fungal/plant class chitinase family in Aspergillus fumigatus

Galactomannan enzyme immunoassay and quantitative Real Time PCR as tools to evaluate the exposure and response in a rat model of aspergillosis after posaconazole prophylaxis

Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species

Genome-Wide Comparative Analysis of Aspergillus fumigatus Strains: The Reference Genome as a Matter of Concern

Genotype distribution of clinical isolates of Trichosporon asahii based on sequencing of intergenic spacer 1.

Halophilic bacteria as a source of novel hydrolytic enzymes

Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi.

Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010). ⬇️

Hospital Environment as a Source of Azole-Resistant <i>Aspergillus fumigatus</i> Strains with TR34/L98H and G448S Cyp51A Mutations

In Vitro Activities of Three Licensed Antifungal Agents against Spanish Clinical Isolates of Aspergillus spp ⬇️

In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis.

In vitro activity of antifungals against Zygomycetes.

In vitro activity of ravuconazole against 923 clinical isolates of nondermatophyte filamentous fungi.

In vivo efficacy of voriconazole and posaconazole therapy in a novel invertebrate model of Aspergillus fumigatus infection

Interlaboratory reproducibility of a microsatellite-based typing assay for Aspergillus fumigatus through the use of allelic ladders: proof of concept

Interlaboratory reproducibility of a single-locus sequence-based method for strain typing of Aspergillus fumigatus

Invasive aspergillosis caused by cryptic Aspergillus species: a report of two consecutive episodes in a patient with leukaemia.

Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for fast and accurate identification of clinically relevant Aspergillus species.

Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability

Molecular identification, antifungal resistance and virulence of Cryptococcus neoformans and Cryptococcus deneoformans isolated in Seville, Spain.

Multiple-Triazole–Resistant Aspergillosis

New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growth

Point Mutations in the 14-α Sterol Demethylase Cyp51A or Cyp51C Could Contribute to Azole Resistance in Aspergillus flavus

Polyphasic characterization of fungal isolates from a published case of invasive aspergillosis reveals misidentification of Aspergillus felis as Aspergillus viridinutans

Population-Based Survey of Filamentous Fungi and Antifungal Resistance in Spain (FILPOP Study).

Population-based survey of filamentous fungi and antifungal resistance in Spain (FILPOP Study).

Proposal for a unified nomenclature for target-site mutations associated with resistance to fungicides

Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus.

Pulmonary mycetoma caused by an atypical isolate of Paecilomyces species in an immunocompetent individual: case report and literature review of Paecilomyces lung infections.

Rapid development of Candida krusei echinocandin resistance during caspofungin therapy

Resistance to voriconazole due to a G448S substitution in Aspergillus fumigatus in a patient with cerebral aspergillosis

Ribosomic DNA intergenic spacer 1 region is useful when identifying Candida parapsilosis spp. complex based on high-resolution melting analysis.

Role of Aspergillus lentulus 14-α sterol demethylase (Cyp51A) in azole drug susceptibility.

Species identification and antifungal susceptibility patterns of species belonging to Aspergillus section Nigri.

Susceptibility testing and molecular classification of Paecilomyces spp.

The ZrfC alkaline zinc transporter is required for Aspergillus fumigatus virulence and its growth in the presence of the Zn/Mn-chelating protein calprotectin.

The non-mammalian hostGalleria mellonellacan be used to study the virulence of the fungal pathogenCandida tropicalisand the efficacy of antifungal drugs during infection by this pathogenic yeast ⬇️

Triazole Resistance in Aspergillus Species: An Emerging Problem

Triazole Resistance in Aspergillus spp.: A Worldwide Problem?

Zygomycosis Caused by Rhizopus microsporus and Rhizopus oryzae in Madhya Pradesh (M.P.) Central India: A Report of Two Cases ⬇️