Lista de obras - Jiri Jiracek - Dominio Público Uruguay

A CuAAC-Hydrazone-CuAAC Trifunctional Scaffold for the Solid-Phase Synthesis of Trimodal Compounds: Possibilities and Limitations

artículo científico publicado en 2015

A new colorimetric assay for methionyl aminopeptidases: examination of the binding of a new class of pseudopeptide analog inhibitors.

artículo científico publicado en 2006

A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding

scientific article published in Journal of Biological Chemistry

Can Arginine Inhibit Insulin Aggregation? A Combined Protein Crystallography, Capillary Electrophoresis, and Molecular Simulation Study

artículo científico publicado en 2018

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

artículo científico publicado en 2017

Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation.

artículo científico publicado en 2018

Determination of pK(a) values of diastereomers of phosphinic pseudopeptides by CZE

artículo científico publicado en 2006

Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.

artículo científico publicado en 2010

Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.

artículo científico publicado en 2004

Evaluation of carrier ampholyte-based capillary electrophoresis for separation of peptides and peptide mimetics.

artículo científico publicado en 2008

From venom peptides to a potential diabetes treatment

scientific article published on 12 February 2019

Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.

artículo científico publicado en 2014

Inhibitors of N(alpha)-acetyl-L-ornithine deacetylase: synthesis, characterization and analysis of their inhibitory potency.

artículo científico publicado en 2009

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

artículo científico publicado en 2014

Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A

artículo científico publicado en 2012

Insulin-Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity.

artículo científico publicado en 2016

Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities.

artículo científico publicado en 2017

Mono-N-acyl-2,6-diaminopimelic acid derivatives: analysis by electromigration and spectroscopic methods and examination of enzyme inhibitory activity.

artículo científico publicado en 2014

Optimized syntheses of Fmoc azido amino acids for the preparation of azidopeptides.

artículo científico publicado en 2017

Pressure assisted partial filling affinity capillary electrophoresis employed for determination of binding constants of human insulin hexamer complexes with serotonin, dopamine, arginine, and phenol

scientific article published on 14 November 2018

Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.

artículo científico publicado en 2016

Quantification of homocysteine-related metabolites and the role of betaine-homocysteine S-methyltransferase in HepG2 cells.

artículo científico publicado en 2012

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

artículo científico publicado en 2016

S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors

artículo científico publicado en 2011

Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain.

artículo científico publicado en 2004

Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs

artículo científico publicado en 2017

Synthesis of α-carboxyphosphinopeptides derived from norleucine.

artículo científico publicado en 2010

The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase

artículo científico publicado en 2013

The use of Fmoc-Lys(Pac)-OH and penicillin G acylase in the preparation of novel semisynthetic insulin analogs

artículo científico publicado en 2007

Two-dimensional electrophoretic comparison of metastatic and non-metastatic human breast tumors using in vitro cultured epithelial cells derived from the cancer tissues.

artículo científico publicado en 2008

Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine

artículo científico publicado en 2010

Lista de obras de Jiri Jiracek

A CuAAC-Hydrazone-CuAAC Trifunctional Scaffold for the Solid-Phase Synthesis of Trimodal Compounds: Possibilities and Limitations

A new colorimetric assay for methionyl aminopeptidases: examination of the binding of a new class of pseudopeptide analog inhibitors.

A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding

Can Arginine Inhibit Insulin Aggregation? A Combined Protein Crystallography, Capillary Electrophoresis, and Molecular Simulation Study

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation.

Determination of pK(a) values of diastereomers of phosphinic pseudopeptides by CZE

Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.

Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.

Evaluation of carrier ampholyte-based capillary electrophoresis for separation of peptides and peptide mimetics.

From venom peptides to a potential diabetes treatment

Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.

Inhibitors of N(alpha)-acetyl-L-ornithine deacetylase: synthesis, characterization and analysis of their inhibitory potency.

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A

Insulin-Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity.

Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities.

Mono-N-acyl-2,6-diaminopimelic acid derivatives: analysis by electromigration and spectroscopic methods and examination of enzyme inhibitory activity.

Optimized syntheses of Fmoc azido amino acids for the preparation of azidopeptides.

Pressure assisted partial filling affinity capillary electrophoresis employed for determination of binding constants of human insulin hexamer complexes with serotonin, dopamine, arginine, and phenol

Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.

Quantification of homocysteine-related metabolites and the role of betaine-homocysteine S-methyltransferase in HepG2 cells.

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors

Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain.

Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs

Synthesis of α-carboxyphosphinopeptides derived from norleucine.

The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase

The use of Fmoc-Lys(Pac)-OH and penicillin G acylase in the preparation of novel semisynthetic insulin analogs

Two-dimensional electrophoretic comparison of metastatic and non-metastatic human breast tumors using in vitro cultured epithelial cells derived from the cancer tissues.

Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine