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Lista de obras de Antonino Neri

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect

artículo científico publicado en 2009

A compendium of DIS3 mutations and associated transcriptional signatures in plasma cell dyscrasias.

artículo científico publicado en 2015

A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma.

artículo científico publicado en 2018

A non-invasive approach to monitor chronic lymphocytic leukemia engraftment in a xenograft mouse model using ultra-small superparamagnetic iron oxide-magnetic resonance imaging (USPIO-MRI).

artículo científico publicado en 2016

A novel mutation involving the carboxy terminal region of the FGFR3 gene in a multiple myeloma patient with t(4;14).

artículo científico publicado en 2002

A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells.

artículo científico publicado en 2014

A progression-risk score to predict treatment-free survival for early stage chronic lymphocytic leukemia patients.

artículo científico publicado en 2015

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

artículo científico publicado en 2010

Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer

scientific article published on 23 January 2017

An Increased Number of Individuals with Clinically Recognized Monoclonal B-Cell Lymphocytosis Characterizes a Recent Database of Chronic Lymphocytic Leukemia Rai Stage 0

artículo científico publicado en 2012

Analysis of p53 and ras gene mutations in endometriosis

scientific article published on 01 January 1994

Analysis of p53 gene mutations in acute myeloid leukemia

scientific article published on 01 August 1994

Anaplastic lymphoma kinase in human cancer

artículo científico publicado en 2011

Arrangements and rearrangements of the human T-cell receptor gamma gene

artículo científico publicado en 1987

Association between gene and miRNA expression profiles and stereotyped subset #4 B-cell receptor in chronic lymphocytic leukemia

artículo científico publicado en 2015

Association between p53 gene mutations and tobacco and alcohol exposure in laryngeal squamous cell carcinoma.

artículo científico publicado en 2004

Autoimmune cytopenias in chronic lymphocytic leukemia

artículo científico publicado en 2014

Autoimmune cytopenias in chronic lymphocytic leukemia at disease presentation in the modern treatment era: is stage C always stage C?

artículo científico publicado en 2013

B-cell receptor configuration and adverse cytogenetics are associated with autoimmune hemolytic anemia in chronic lymphocytic leukemia

artículo científico publicado en 2012

Bendamustine in combination with ofatumumab in relapsed or refractory chronic lymphocytic leukemia: a GIMEMA Multicenter Phase II Trial.

artículo científico publicado en 2013

Biological and clinical relevance of miRNA expression signatures in primary plasma cell leukemia.

artículo científico publicado en 2013

Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia

artículo científico publicado en 2011

Biological and molecular characterization of a rare case of cutaneous Richter syndrome.

artículo científico publicado en 2016

Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines.

artículo científico publicado en 2017

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

artículo científico publicado en 2010

CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib

artículo científico publicado en 2007

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

artículo científico publicado en 2012

Cell cycle regulators in multiple myeloma: prognostic implications of p53 nuclear accumulation.

artículo científico publicado en 2003

Characterization of oncogene dysregulation in multiple myeloma by combined FISH and DNA microarray analyses

artículo científico publicado en 2005

Characterization of the t(4;14)(p16.3;q32) in the KMS-18 multiple myeloma cell line.

artículo científico publicado en 2001

Chromosome 11q23.1 is an unstable region in B-cell tumor cell lines.

artículo científico publicado en 2011

Chromosome 2p gain in monoclonal B-cell lymphocytosis and in early stage chronic lymphocytic leukemia.

artículo científico publicado en 2012

Circulating tumor DNA as a liquid biopsy in plasma cell dyscrasias

scientific article published on 22 February 2018

Circulating tumor DNA reveals genetics, clonal evolution and residual disease in classical Hodgkin lymphoma.

artículo científico publicado en 2018

Clinical categories identified by a new prognostic index reflect biological characteristics of patients in early chronic lymphocytic leukemia: The Gruppo Italiano Studio Linfomi (GISL) experience

artículo científico publicado en 2010

Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features.

artículo científico publicado en 2013

Clinical relevance of cyclin D1 protein overexpression in laryngeal squamous cell carcinoma

scientific article published on 01 September 1998

Clinical relevance of expression of the CIP/KIP cell-cycle inhibitors p21 and p27 in laryngeal cancer

artículo científico publicado en 1999

Clinical relevance of hypogammaglobulinemia, clinical and biologic variables on the infection risk and outcome of patients with stage A chronic lymphocytic leukemia

artículo científico publicado en 2017

Clonal evolution in therapy-related neoplasms.

artículo científico publicado en 2017

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers

artículo científico publicado en 2016

Comparison between the CLL-IPI and the Barcelona-Brno prognostic model: Analysis of 1299 newly diagnosed cases.

artículo científico publicado en 2017

Compendium of FAM46C gene mutations in plasma cell dyscrasias.

artículo científico publicado en 2015

Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting.

artículo científico publicado en 2009

Consensus statement from European experts on the diagnosis, management, and treatment of multiple myeloma: from standard therapy to novel approaches.

scientific article published on August 2010

Correction: miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

artículo científico publicado en 2018

Cutaneous localization in multiple myeloma in the context of bortezomib-based treatment: how do myeloma cells escape from the bone marrow to the skin?

artículo científico publicado en 2016

Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation.

artículo científico publicado en 2003

Cyclin D3 immunoreactivity in follicular lymphoma is independent of the t(6;14)(p21.1;q32.3) translocation orcyclin D3 gene amplification and is correlated with histologic grade and Ki-67 labeling index

article

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

artículo científico publicado en 2012

Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemia

artículo científico publicado en 2009

Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.

artículo científico publicado en 2017

Diagnostic role and prognostic significance of a simplified immunophenotypic classification of mature B cell chronic lymphoid leukemias

artículo científico publicado en 2003

Differential repetitive DNA methylation in multiple myeloma molecular subgroups.

artículo científico publicado en 2009

Dioxin exposure of human CD34+ hemopoietic cells induces gene expression modulation that recapitulates its in vivo clinical and biological effects

artículo científico publicado en 2011

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.

artículo científico publicado en 2015

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma.

artículo científico publicado en 2016

Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia

artículo científico publicado en 2013

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

artículo científico publicado en 2009

Does adiponectin act as an antiangiogenic factor in B-cell chronic lymphocytic leukemia?

artículo científico publicado en 2009

Double productive immunoglobulin sequence rearrangements in patients with chronic lymphocytic leukemia.

artículo científico publicado en 2013

Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.

artículo científico publicado en 2018

EGFR through STAT3 modulates ΔN63α expression to sustain tumor-initiating cell proliferation in squamous cell carcinomas.

artículo científico publicado en 2013

Effects of miRNA-15 and miRNA-16 expression replacement in chronic lymphocytic leukemia: implication for therapy

artículo científico publicado en 2017

EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells.

artículo científico publicado en 2017

External validation on a prospective basis of a nomogram for predicting the time to first treatment in patients with chronic lymphocytic leukemia

artículo científico publicado en 2012

Frequency and clinical relevance of coding and noncoding NOTCH1 mutations in early stage Binet A chronic lymphocytic leukemia patients

scientific article published on 25 February 2020

Frequency of RAS and p53 mutations in acute promyelocytic leukemias

scientific article published on 01 November 1993

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.

artículo científico publicado en 2006

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

artículo científico publicado en 2016

Gene array profile identifies collagen type XV as a novel human osteoblast-secreted matrix protein

artículo científico publicado en 2009

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

artículo científico publicado en 2001

Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma.

artículo científico publicado en 2009

Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma

article

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

artículo científico publicado en 2010

Genome-wide analysis of primary plasma cell leukemia identifies recurrent imbalances associated with changes in transcriptional profiles

article

Genomic profiling of enzastaurin-treated B cell lymphoma RL cells.

artículo científico publicado en 2010

Genotypic monoclonality in immunophenotypically polyclonal orbital lymphoid tumors. A model of tumor progression in the lymphoid system. The 1986 Wendell Hughes lecture.

artículo científico publicado en 1987

Global methylation patterns in primary plasma cell leukemia

scientific article published on 18 September 2018

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

artículo científico publicado en 2010

Heterogeneous expression of the collagen receptor DDR1 in chronic lymphocytic leukaemia and correlation with progression.

artículo científico publicado en 2017

Heterogeneous pattern of chromosomal breakpoints involving the MYC locus in multiple myeloma.

artículo científico publicado en 2003

High-throughput sequencing for the identification of NOTCH1 mutations in early stage chronic lymphocytic leukaemia: biological and clinical implications

artículo científico publicado en 2014

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

artículo científico publicado en 2013

IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts.

artículo científico publicado en 2017

ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma

artículo científico publicado en 2017

IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy

artículo científico publicado en 2001

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

artículo científico publicado en 2012

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

artículo científico publicado en 2015

Identification of a novel IGH-MMSET fusion transcript in a human myeloma cell line with the t(4;14)(p16.3;q32) chromosomal translocation

artículo científico publicado en 2004

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma.

artículo científico publicado en 2009

Identification of primary MAFB target genes in multiple myeloma.

artículo científico publicado en 2008

Identification of small molecules uncoupling the Notch::Jagged interaction through an integrated high-throughput screening.

artículo científico publicado en 2017

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

artículo científico publicado en 2015

IgV gene intraclonal diversification and clonal evolution in B-cell chronic lymphocytic leukaemia.

artículo científico publicado en 2006

Immune thrombocytopenia in patients with chronic lymphocytic leukemia is associated with stereotyped B-cell receptors.

artículo científico publicado en 2012

Immunoglobulin heavy chain variable region gene and prediction of time to first treatment in patients with chronic lymphocytic leukemia: Mutational load or mutational status? Analysis of 1003 cases

scientific article published on 30 July 2018

Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules

artículo científico publicado en 2012

Immunoreactivity for cyclin D1 is a reliable marker of gene aberration in plasma cell myeloma but does not specify patients prognosis

article

Immunoreactivity for cyclin D3 is frequently detectable in high-grade primary gastric lymphomas in the absence of the t(6;14)(p21.1;q32.3) chromosomal translocation.

artículo científico publicado en 2003

Impact of B-cell count and imaging screening in cMBL: any need to revise the current guidelines?

scientific article published on 30 January 2012

Impact of host genes and strand selection on miRNA and miRNA* expression.

artículo científico publicado en 2011

Improved risk stratification in myeloma using a microRNA-based classifier.

artículo científico publicado en 2013

In Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma.

artículo científico publicado en 2016

Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways

scientific article published on 14 January 2017

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation.

artículo científico publicado en 2012

Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma

artículo científico publicado en 2017

Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia

artículo científico publicado en 2015

Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma

artículo científico publicado en 2015

Integrative genomic analysis reveals distinct transcriptional and genetic features associated with chromosome 13 deletion in multiple myeloma

artículo científico publicado en 2007

Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

artículo científico publicado en 2010

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

artículo científico publicado en 2009

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

artículo científico publicado en 2009

Intraclonal cell expansion and selection driven by B cell receptor in chronic lymphocytic leukemia

artículo científico publicado en 2011

Is ZAP70 still a key prognostic factor in early stage chronic lymphocytic leukaemia? Results of the analysis from a prospective multicentre observational study.

artículo científico publicado en 2014

Kaposi's Sarcoma-Associated Herpesvirus Infection and Multiple Myeloma

artículo científico publicado en 1997

Lack of Bcl10 gene mutations in laryngeal squamous cell carcinoma

scientific article published on 01 August 2002

Long Non-Coding RNAs in Multiple Myeloma

artículo científico publicado en 2018

Long non-coding RNAs in B-cell malignancies: a comprehensive overview.

artículo científico publicado en 2017

Long non-coding RNAs in normal and malignant hematopoiesis

artículo científico publicado en 2016

Long term assessment of intralipotherapy in Madelung's disease

artículo científico publicado en 2014

Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells

artículo científico publicado en 2010

Low dose alemtuzumab in patients with fludarabine-refractory chronic lymphocytic leukemia

scientific article published on 05 January 2012

Low-dose subcutaneous alemtuzumab in refractory chronic lymphocytic leukaemia (CLL): results of a prospective, single-arm multicentre study.

artículo científico publicado en 2009

Low-grade MALT lymphoma involving multiple mucosal sites and bone marrow

artículo científico publicado en 1998

Meeting report on recent advances on T-lymphocytes in normal and leukemia patients.

artículo científico publicado en 1985

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence.

artículo científico publicado en 2018

Microvessel density, a surrogate marker of angiogenesis, is significantly related to survival in multiple myeloma patients

artículo científico publicado en 2002

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine

artículo científico publicado en 2015

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2008

Molecular and transcriptional characterization of the novel 17p11.2-p12 amplicon in multiple myeloma.

artículo científico publicado en 2007

Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.

artículo científico publicado en 2007

Molecular classification of multiple myeloma: a distinct transcriptional profile characterizes patients expressing CCND1 and negative for 14q32 translocations.

artículo científico publicado en 2005

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

artículo científico publicado en 2013

Molecular prediction of durable remission after first-line fludarabine-cyclophosphamide-rituximab in chronic lymphocytic leukemia

artículo científico publicado en 2015

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

artículo científico publicado en 2015

Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature

artículo científico publicado en 2016

Molecular targeting of the PKC-beta inhibitor enzastaurin (LY317615) in multiple myeloma involves a coordinated downregulation of MYC and IRF4 expression

artículo científico publicado en 2009

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche

artículo científico publicado en 2016

Multiplex ligation-dependent probe amplification and fluorescence in situ hybridization to detect chromosomal abnormalities in Chronic lymphocytic leukemia: A comparative study

scientific article published on 02 June 2011

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

artículo científico publicado en 2012

Non-negative matrix factorization to perform unsupervised clustering of genome wide DNA profiles in mature B cell lymphoid neoplasms

scientific article published on 28 April 2010

Notch pathway promotes ovarian cancer growth and migration via CXCR4/SDF1α chemokine system

artículo científico publicado en 2015

Notch signaling deregulation in multiple myeloma: A rational molecular target

artículo científico publicado en 2015

Notch signaling drives multiple myeloma induced osteoclastogenesis.

artículo científico publicado en 2014

Oct-4 expression in adult human differentiated cells challenges its role as a pure stem cell marker.

artículo científico publicado en 2007

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations

article

PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation

artículo científico publicado en 2015

Pathogenicity of in-vivo generated intestinal Th17 lymphocytes is IFNγ dependent.

artículo científico publicado en 2018

Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b

artículo científico publicado en 2009

Predictive value of the CLL-IPI in CLL patients receiving chemo-immunotherapy as first-line treatment

artículo científico publicado en 2018

Primary Plasma Cell Leukemia: Identity Card 2016.

artículo científico publicado en 2016

Primary Soft Tissue Lymphomas: Description of Seven Cases and Review of the Literature

artículo científico publicado en 2016

Primary plasma cell leukemia 2.0: advances in biology and clinical management.

artículo científico publicado en 2016

Primary plasma cell leukemia in the era of new drugs: has something changed?

artículo científico publicado en 2011

Prognostic relevance of serum levels and cellular expression of adiponectin in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2008

Prognostic relevance ofin vitroresponse to cell stimulation via surface IgD in binet stage a CLL

artículo científico publicado en 2009

Prospective validation of a risk score based on biological markers for predicting progression free survival in Binet stage A chronic lymphocytic leukemia patients: Results of the multicenter O-CLL1-GISL study

artículo científico publicado en 2014

Prospective validation of predictive value of abdominal computed tomography scan on time to first treatment in Rai 0 chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study

artículo científico publicado en 2015

Rearranged NFKB-2 Genes in Lymphoid Neoplasms Code for Constitutively Active Nuclear Transactivators ⬇️

artículo científico publicado el 1 de septiembre de 1995

Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1

artículo científico publicado en 2003

Relevance of Ras gene mutations in the context of the molecular heterogeneity of multiple myeloma.

artículo científico publicado en 2007

Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia

artículo científico publicado en 2014

Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

artículo científico publicado en 2014

Response of AIHA to high dose intravenous immunoglobulins in a patient with ovarian teratoma

artículo científico publicado en 2009

Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.

artículo científico publicado en 2015

Serum level of CD26 predicts time to first treatment in early B-chronic lymphocytic leukemia

artículo científico publicado en 2009

Serum levels of soluble calreticulin predict for time to first treatment in early chronic lymphocytic leukaemia.

artículo científico publicado en 2016

Serum thrombopoietin compared with ZAP-70 and immunoglobulin heavy-chain gene mutation status as a predictor of time to first treatment in early chronic lymphocytic leukemia

article

Should pre-transfusion screening RBC panels contain Wr(a+) cells?

artículo científico publicado en 2010

Single-agent Smac-mimetic compounds induce apoptosis in B chronic lymphocytic leukaemia (B-CLL)

artículo científico publicado en 2013

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

artículo científico publicado en 2013

Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited antitumor activity

artículo científico publicado en 2021

Surrogate molecular markers for IGHV mutational status in chronic lymphocytic leukemia for predicting time to first treatment

artículo científico

Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.

artículo científico publicado en 2012

Targeting COPZ1 non-oncogene addiction counteracts the viability of thyroid tumor cells

artículo científico publicado en 2017

Targeting Notch as a Therapeutic Approach for Human Malignancies

artículo científico publicado en 2016

Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth

artículo científico publicado en 2013

Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity.

artículo científico publicado en 2014

Thalidomide downregulates angiogenic genes in bone marrow endothelial cells of patients with active multiple myeloma.

artículo científico publicado en 2005

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells

artículo científico publicado en 2012

The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.

artículo científico publicado en 2014

The chronic lymphocytic leukemia international prognostic index predicts time to first treatment in early CLL: Independent validation in a prospective cohort of early stage patients.

artículo científico publicado en 2016

The clinical and biological features of a series of immunophenotypic variant of B-CLL

artículo científico publicado en 2010

The cumulative amount of serum-free light chain is a strong prognosticator in chronic lymphocytic leukemia

artículo científico publicado en 2011

The expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma.

artículo científico publicado en 2012

The oral protein-kinase C beta inhibitor enzastaurin (LY317615) suppresses signalling through the AKT pathway, inhibits proliferation and induces apoptosis in multiple myeloma cell lines.

artículo científico publicado en 2008

The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.

artículo científico publicado en 2010

The reconstruction of transcriptional networks reveals critical genes with implications for clinical outcome of multiple myeloma

artículo científico publicado en 2011

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

artículo científico publicado en 2015

The small GTPase RhoU lays downstream of JAK/STAT signaling and mediates cell migration in multiple myeloma.

artículo científico publicado en 2018

The utility of two prognostic models for predicting time to first treatment in early chronic lymphocytic leukemia patients: results of a comparative analysis.

artículo científico publicado en 2013

Therapeutic Targeting of miR-29b/HDAC4 Epigenetic Loop in Multiple Myeloma

Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92

scientific article published on 11 July 2018

Total body computed tomography scan in the initial work-up of Binet stage A chronic lymphocytic leukemia patients: Results of the prospective, multicenter O-CLL1-GISL study

artículo científico publicado en 2013

Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma

artículo científico publicado en 2005

Transcriptional characterization of a prospective series of primary plasma cell leukemia revealed signatures associated with tumor progression and poorer outcome.

artículo científico publicado en 2013

Transcriptional features of multiple myeloma patients with chromosome 1q gain

artículo científico publicado en 2007

Translocation T(4;14)(p16.3;q32) is a recurrent genetic lesion in primary amyloidosis

artículo científico publicado en 2001

Treatment and prognosis in a series of primary extranodal lymphomas of the ocular adnexa

artículo científico publicado en 1998

Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma.

artículo científico publicado en 2007

Utilizing next-generation sequencing in the management of multiple myeloma.

artículo científico

Validation of a biological score to predict response in chronic lymphocytic leukemia patients treated front-line with bendamustine and rituximab

artículo científico publicado en 2018

Validation of a survival-risk score (SRS) in relapsed/refractory CLL patients treated with idelalisib-rituximab

scientific article published on 16 September 2020

Validation of the CLL-IPI and comparison with the MDACC prognostic index in newly diagnosed patients.

artículo científico publicado en 2016

Whole-exome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns.

artículo científico publicado en 2015

lncRNA profiling in early-stage chronic lymphocytic leukemia identifies transcriptional fingerprints with relevance in clinical outcome

artículo científico publicado en 2016

miR-22 suppresses DNA ligase III addiction in multiple myeloma

artículo científico publicado en 2018

miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth.

artículo científico publicado en 2016

miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells

artículo científico publicado en 2013

miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1

artículo científico publicado en 2012

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

artículo científico

microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters

scientific article published on 10 June 2014

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