Lista de obras - Thomas Reinheckel - Dominio Público Uruguay

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d

artículo científico publicado en 2016

A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion

artículo científico publicado en 2017

A role for cathepsin E in the processing of mast-cell carboxypeptidase A.

artículo científico publicado en 2005

A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis

artículo científico publicado en 2017

A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins

scientific article published on 01 June 2007

Activation of the Nipah virus fusion protein in MDCK cells is mediated by cathepsin B within the endosome-recycling compartment.

artículo científico publicado en 2012

Adaptation of protein carbonyl detection to the requirements of proteome analysis demonstrated for hypoxia/reoxygenation in isolated rat liver mitochondria

artículo científico publicado en 2000

Allergic Airway Inflammation in Mice Deficient for the Antigen-Processing Protease Cathepsin E

An open source protein gel documentation system for proteome analyses

artículo científico publicado en 2004

Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation

scientific article published on 24 October 2018

B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model

artículo científico publicado en 2019

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

artículo científico publicado en 2020

CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts--a bioinformatical analysis

artículo científico publicado en 2009

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

scientific journal article

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

artículo científico publicado en 2012

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

artículo científico publicado en 2014

Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity.

artículo científico publicado en 2006

Cardiac and ocular pathologies in a mouse model of mucopolysaccharidosis type VI.

artículo científico publicado en 2003

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

artículo científico publicado en 2008

Cathepsin B & L are not required for ebola virus replication

artículo científico publicado en 2012

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

artículo científico publicado en 2017

Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection

artículo científico publicado en 2014

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice

artículo científico publicado en 2011

Cathepsin B release from rodent intestine mucosa due to mechanical injury results in extracellular matrix damage in early post-traumatic phases

artículo científico publicado en 2009

Cathepsin B-deficient mice as source of monoclonal anti-cathepsin B antibodies

artículo científico publicado en 2015

Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.

artículo científico publicado en 2013

Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling

scientific article published on 12 October 2020

Cathepsin D is one of the major enzymes involved in intracellular degradation of AGE-modified proteins.

artículo científico publicado en 2010

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.

artículo científico publicado en 2017

Cathepsin E Deficiency Ameliorates Graft-versus-Host Disease and Modifies Dendritic Cell Motility.

artículo científico publicado en 2017

Cathepsin G in Experimental Tuberculosis: Relevance for Antibacterial Protection and Potential for Immunotherapy

artículo científico publicado en 2015

Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling

artículo científico publicado en 2021

Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters.

artículo científico publicado en 2012

Cathepsin H is an additional convertase of pro-granzyme B

artículo científico publicado en 2010

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

artículo científico publicado en 2003

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

artículo científico publicado en 2009

Cathepsin L is crucial for the development of early experimental diabetic nephropathy

artículo científico publicado en 2016

Cathepsin L is required for endothelial progenitor cell-induced neovascularization

artículo científico publicado en 2005

Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression.

artículo científico publicado en 2009

Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression

scientific journal article

Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.

scientific article published on 07 July 2009

Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain.

artículo científico publicado en 2016

Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice

artículo científico publicado en 2013

Cathepsins D and L reduce the toxicity of advanced glycation end products.

artículo científico publicado en 2012

Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression

artículo científico publicado en 2014

Cellular senescence induced by cathepsin X downregulation.

artículo científico publicado en 2011

Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes.

artículo científico publicado en 2018

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

artículo científico publicado en 1998

Comparison of protein oxidation and aldehyde formation during oxidative stress in isolated mitochondria.

artículo científico publicado en 1998

Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression

scientific article published on 22 July 2020

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts ⬇️

artículo científico publicado el 1 de noviembre de 2011

Cylinder implantation--a new method for endoscopic treatment of anastomotic dehiscence

artículo científico publicado en 1998

Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.

artículo científico publicado en 2006

Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment

artículo científico publicado en 2012

Degradation of hypochlorite-damaged glucose-6-phosphate dehydrogenase by the 20S proteasome.

artículo científico publicado en 1999

Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome.

artículo científico publicado en 1996

Degradation of oxidized proteins in mammalian cells.

artículo científico publicado en 1997

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

artículo científico publicado en 2012

Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target.

artículo científico publicado en 2012

Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress

scientific article published on 01 May 2000

Differential oxidative injury in extrapancreatic tissues during experimental pancreatitis: modification of lung proteins by 4-hydroxynonenal.

artículo científico publicado en 2001

Differentially expressed genes in hippocampal cell cultures in response to an excitotoxic insult by quinolinic acid.

artículo científico publicado en 1998

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis.

artículo científico publicado en 2016

Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.

artículo científico publicado en 2011

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

artículo científico publicado en 2014

Distinct protease requirements for antigen presentation in vitro and in vivo.

artículo científico publicado en 2010

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

artículo científico publicado en 2006

Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.

artículo científico publicado en 2013

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

artículo científico publicado en 2007

Endoscopic treatment of clinically symptomatic leaks of thoracic esophageal anastomoses

scientific article published on 01 January 2000

Evaluation of UVA-mediated oxidative damage to proteins and lipids in extracorporeal photoimmunotherapy

artículo científico publicado en 1999

Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment

scientific article published on 07 August 2011

Gene targeting of the cysteine peptidase cathepsin H impairs lung surfactant in mice

artículo científico publicado en 2011

Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein

artículo científico publicado en 2009

Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.

artículo científico publicado en 2010

Impact of cathepsin B on the interstitial fluid proteome of murine breast cancers

artículo científico publicado en 2015

Impact of proteolysis on cancer stem cell functions

artículo científico publicado en 2019

In Vivo Imaging of Antileukemic Drug Asparaginase Reveals a Rapid Macrophage-Mediated Clearance from the Bone Marrow

artículo científico publicado en 2016

Induction of premalignant host responses by cathepsin x/z-deficiency in Helicobacter pylori-infected mice.

artículo científico publicado en 2013

Inherited diseases caused by mutations in cathepsin protease genes.

artículo científico publicado en 2016

Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation

artículo científico publicado en 2013

LIMP-2 links late phagosomal trafficking with the onset of the innate immune response to Listeria monocytogenes: a role in macrophage activation

artículo científico publicado en 2010

Legumain is activated in macrophages during pancreatitis

artículo científico publicado en 2016

Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion.

artículo científico publicado en 2017

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes.

artículo científico publicado en 2010

Lysosomal processing of progranulin

artículo científico publicado en 2017

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

artículo científico publicado en 2018

Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells.

artículo científico publicado en 2015

Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice

scientific article published on 24 April 2006

Lysosome-Dependent Activation of Human Dendritic Cells by the Vaccine Adjuvant QS-21.

artículo científico publicado en 2016

MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions

artículo científico publicado en 2018

Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression

artículo científico publicado en 2008

Micromolar calcium prevents isolated rat liver mitochondria from anoxia-reoxygenation injury

scientific article published on 01 September 1997

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis

scientific article published on 14 June 2018

Molecular characterization of arylsulfatase G: expression, processing, glycosylation, transport, and activity

artículo científico publicado en 2014

Murine and human cathepsin B exhibit similar properties: possible implications for drug discovery

artículo científico publicado en 2009

Mutations in LRPAP1 are associated with severe myopia in humans

artículo científico publicado en 2013

Neuroectoderm-specific deletion of cathepsin D in mice models human inherited neuronal ceroid lipofuscinosis type 10.

artículo científico publicado en 2015

Neuronal-specific microexon splicing of TAF1 mRNA is directly regulated by SRRM4/nSR100

scientific article published on 27 September 2019

Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS

artículo científico publicado en 2016

New Kid on the Block

artículo científico publicado en 2017

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells

artículo científico publicado en 2015

Occurrence of oxidatively modified proteins: an early event in experimental acute pancreatitis

artículo científico publicado en 1998

On the road to inflammation: Linking lysosome disruption, lysosomal protease release and necrotic death of immune cells ⬇️

artículo científico publicado el 11 de junio de 2013

Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone

artículo científico publicado en 2006

Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.

artículo científico publicado en 2014

Oxidative stress affects pancreatic proteins during the early pathogenesis of rat caerulein pancreatitis

artículo científico publicado en 1999

Oxidative stress in lung tissue induced by CO(2) pneumoperitoneum in the rat

artículo científico publicado en 2000

Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones

artículo científico publicado en 1999

Profiling trait anxiety: transcriptome analysis reveals cathepsin B (Ctsb) as a novel candidate gene for emotionality in mice

artículo científico publicado en 2011

Proteasome-dependent turnover of protein disulfide isomerase in oxidatively stressed cells.

artículo científico publicado en 2002

Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome.

artículo científico publicado en 1995

Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer

scientific article published on 16 August 2016

Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein CLN7 ⬇️

artículo científico publicado el 2 de junio de 2012

Proteomic analysis of lung metastases in a murine breast cancer model reveals divergent influence of CTSB and CTSL overexpression.

artículo científico publicado en 2017

Reduced neutrophil sequestration in lung tissue after laparoscopic lavage in a rat peritonitis model

artículo científico publicado en 2001

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

artículo científico publicado en 2008

Role of endogenous and exogenous antioxidants in the defence against functional damage and lipid peroxidation in rat liver mitochondria

artículo científico publicado en 1997

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.

artículo científico publicado en 2013

Short-term impairment of energy production in isolated rat liver mitochondria by hypoxia/reoxygenation: involvement of oxidative protein modification ⬇️

artículo científico publicado el 15 de noviembre de 1997

Single nephron proteomes connect morphology and function in proteinuric kidney disease.

artículo científico publicado en 2018

Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation

scientific article published on 13 January 2020

Specialized roles for cysteine cathepsins in health and disease.

artículo científico publicado en 2010

Specific functions of lysosomal proteases in endocytic and autophagic pathways.

artículo científico publicado en 2011

Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model.

artículo científico publicado en 2013

Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression

artículo científico publicado en 2015

Studies of intestinal morphology and cathepsin B expression in a transgenic mouse aiming at intestine-specific expression of Cath B-EGFP.

artículo científico publicado en 2011

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

artículo científico publicado en 2010

The PI3K regulatory subunits p55α and p50α regulate cell death in vivo.

artículo científico publicado en 2014

The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length

artículo científico publicado en 2014

The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea.

artículo científico publicado en 2010

The endolysosomal cysteine cathepsins L and K are involved in macrophage-mediated clearance of Staphylococcus aureus and the concomitant cytokine induction

artículo científico publicado en 2013

The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.

artículo científico publicado en 2004

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

artículo científico publicado en 2005

The role of proteases in epithelial-to-mesenchymal cell transitions in cancer

artículo científico publicado en 2019

The secreted inhibitor of invasive cell growth CREG1 is negatively regulated by cathepsin proteases

scientific article published on 08 May 2020

Thyroid functions of mouse cathepsins B, K, and L

article published in 2003

Thyroid functions of mouse cathepsins B, K, and L.

artículo científico publicado en 2003

Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice

artículo científico publicado en 2014

Toward computer-based cleavage site prediction of cysteine endopeptidases

artículo científico publicado en 2003

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

artículo científico publicado en 2010

Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model.

artículo científico publicado en 2008

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

artículo científico publicado en 2006

Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes.

artículo científico publicado en 2018

Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor.

artículo científico publicado en 2010

Lista de obras de Thomas Reinheckel

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d

A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion

A role for cathepsin E in the processing of mast-cell carboxypeptidase A.

A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis

A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins

Activation of the Nipah virus fusion protein in MDCK cells is mediated by cathepsin B within the endosome-recycling compartment.

Adaptation of protein carbonyl detection to the requirements of proteome analysis demonstrated for hypoxia/reoxygenation in isolated rat liver mitochondria

Allergic Airway Inflammation in Mice Deficient for the Antigen-Processing Protease Cathepsin E

An open source protein gel documentation system for proteome analyses

Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation

B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts--a bioinformatical analysis

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity.

Cardiac and ocular pathologies in a mouse model of mucopolysaccharidosis type VI.

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

Cathepsin B & L are not required for ebola virus replication

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice

Cathepsin B release from rodent intestine mucosa due to mechanical injury results in extracellular matrix damage in early post-traumatic phases

Cathepsin B-deficient mice as source of monoclonal anti-cathepsin B antibodies

Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.

Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling

Cathepsin D is one of the major enzymes involved in intracellular degradation of AGE-modified proteins.

Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.

Cathepsin E Deficiency Ameliorates Graft-versus-Host Disease and Modifies Dendritic Cell Motility.

Cathepsin G in Experimental Tuberculosis: Relevance for Antibacterial Protection and Potential for Immunotherapy

Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling

Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters.

Cathepsin H is an additional convertase of pro-granzyme B

Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.

Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.

Cathepsin L is crucial for the development of early experimental diabetic nephropathy

Cathepsin L is required for endothelial progenitor cell-induced neovascularization

Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression.

Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression

Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.

Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain.

Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice

Cathepsins D and L reduce the toxicity of advanced glycation end products.

Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression

Cellular senescence induced by cathepsin X downregulation.

Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes.

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

Comparison of protein oxidation and aldehyde formation during oxidative stress in isolated mitochondria.

Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts ⬇️

Cylinder implantation--a new method for endoscopic treatment of anastomotic dehiscence

Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.

Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment

Degradation of hypochlorite-damaged glucose-6-phosphate dehydrogenase by the 20S proteasome.

Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome.

Degradation of oxidized proteins in mammalian cells.

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target.

Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress

Differential oxidative injury in extrapancreatic tissues during experimental pancreatitis: modification of lung proteins by 4-hydroxynonenal.

Differentially expressed genes in hippocampal cell cultures in response to an excitotoxic insult by quinolinic acid.

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis.

Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Distinct protease requirements for antigen presentation in vitro and in vivo.

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

Endoscopic treatment of clinically symptomatic leaks of thoracic esophageal anastomoses

Evaluation of UVA-mediated oxidative damage to proteins and lipids in extracorporeal photoimmunotherapy

Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment

Gene targeting of the cysteine peptidase cathepsin H impairs lung surfactant in mice

Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein

Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.

Impact of cathepsin B on the interstitial fluid proteome of murine breast cancers

Impact of proteolysis on cancer stem cell functions

In Vivo Imaging of Antileukemic Drug Asparaginase Reveals a Rapid Macrophage-Mediated Clearance from the Bone Marrow

Induction of premalignant host responses by cathepsin x/z-deficiency in Helicobacter pylori-infected mice.