Lista de obras - José C García-Borrón - Dominio Público Uruguay

A new spectrophotometric assay for dopachrome tautomerase

artículo científico publicado en 1990

A three-dimensional model of mammalian tyrosinase active site accounting for loss of function mutations

scientific article published on 01 October 2007

Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady-state retention of mutant forms in the proximal golgi

artículo científico publicado en 2009

After dopachrome

scientific article published on 01 December 1991

Agonist-independent, high constitutive activity of the human melanocortin 1 receptor.

artículo científico publicado en 2004

Alpha-MSH and other melanogenic activators mediate opposite effects on tyrosinase and dopachrome tautomerase in B16/F10 mouse melanoma cells

scientific article published on 01 October 1992

Anti-inflammatory and anti-invasive effects of α-melanocyte-stimulating hormone in human melanoma cells ⬇️

artículo científico publicado el 17 de noviembre de 2003

Apoptosis and molecular pathways in the seminiferous epithelium of aged and photoinhibited Syrian hamsters (Mesocricetus auratus).

artículo científico publicado en 2006

Association of Melanocortin-1 Receptor Variants with Pigmentary Traits in Humans: A Pooled Analysis from the M-Skip Project ⬇️

artículo científico publicado en 2016

Comparative action of dopachrome tautomerase and metal ions on the rearrangement of dopachrome

artículo científico publicado en 1991

Comparison of TRPs from murine and human malignant melanocytes

scientific article published on 01 August 1997

Conformational studies of soluble and immobilized frog epidermis tyrosinase by fluorescence

artículo científico publicado en 1984

Conjugation with Dihydrolipoic Acid Imparts Caffeic Acid Ester Potent Inhibitory Effect on Dopa Oxidase Activity of Human Tyrosinase

artículo científico publicado en 2018

Differential and competitive regulation of human melanocortin 1 receptor signaling by β-arrestin isoforms ⬇️

artículo científico publicado el 7 de junio de 2013

Dopachrome tautomerase decreases the binding of indolic melanogenesis intermediates to proteins

artículo científico publicado en 1994

Effect of detergents and endogenous lipids on the activity and properties of tyrosinase and its related proteins

artículo científico publicado en 1995

Elevated glucocorticoid levels are responsible for induction of tyrosine hydroxylase mRNA expression, phosphorylation, and enzyme activity in the nucleus of the solitary tract during morphine withdrawal

artículo científico publicado en 2009

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor.

artículo científico publicado en 2015

Functional interplay between secreted ligands and receptors in melanoma

artículo científico publicado en 2017

Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.

artículo científico publicado en 2012

Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase.

artículo científico publicado en 2017

Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients.

artículo científico publicado en 2009

Identification and functional characterization of natural human melanocortin 1 receptor mutant alleles in Pakistani population.

artículo científico publicado en 2015

Identification of active site residues involved in metal cofactor binding and stereospecific substrate recognition in Mammalian tyrosinase. Implications to the catalytic cycle.

artículo científico publicado en 2002

Improved tyrosinase activity stains in polyacrylamide electrophoresis gels

artículo científico publicado en 1993

Incorporation of bovine thyroid peroxidase in liposomes

scientific article published on 01 March 1984

Is dopachrome tautomerase necessary to get DHICA from dopachrome?

artículo científico publicado en 1994

Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function.

artículo científico publicado en 2002

MC1R signaling. Intracellular partners and pathophysiological implications

artículo científico publicado en 2017

MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project. ⬇️

artículo científico publicado en 2018

MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project

artículo científico publicado en 2014

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

artículo científico publicado en 2014

Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas

artículo científico publicado en 2009

Melanocortin 1 receptor and skin pathophysiology: beyond colour, much more than meets the eye

scientific article published on 01 June 2014

Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology.

artículo científico publicado en 2006

Melanocortin-1 receptor structure and functional regulation.

artículo científico publicado en 2005

Melanocortin-1 receptor, skin cancer and phenotypic characteristics (M-SKIP) project: study design and methods for pooling results of genetic epidemiological studies ⬇️

artículo científico publicado el 3 de agosto de 2012

Melanocyte stimulating hormone activation of tyrosinase in B16 mouse melanoma cells. Evidence for a differential induction of two distinct isoenzymes

scientific article published on 01 June 1992

Molecular anatomy of tyrosinase and its related proteins: beyond the histidine-bound metal catalytic center.

artículo científico publicado en 2002

Molecular basis of the extreme dilution mottled mouse mutation: a combination of coding and noncoding genomic alterations

scientific journal article

Molecular interactions within the melanogenic complex: formation of heterodimers of tyrosinase and TRP1 from B16 mouse melanoma

scientific journal article

New insights on the structure of the mouse silver locus and on the function of the silver protein

artículo científico publicado en 2000

N‐glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role ⬇️

artículo científico publicado el 5 de abril de 2011

Partial characterization of IR-alpha-MSH peptides found in melanoma tumors

artículo científico publicado el 1 de septiembre de 1992

Preparation of purified tyrosinase devoid of dopachrome tautomerase from mammalian malignant melanocytes

scientific article published on 01 June 1993

Quantitative determination of tryptophanyl and tyrosyl residues of proteins by second-derivative fluorescence spectroscopy

scientific article published on 01 September 1982

Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer

artículo científico publicado en 2006

Regulation of mammalian melanogenesis. I: Partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase

scientific journal article

Regulation of mammalian melanogenesis. II: The role of metal cations

artículo científico publicado en 1990

Regulation of the cytosolic and melanosome-bound tyrosinase activities in Harding-Passey mouse melanoma

scientific article published on 01 January 1985

Regulation of the final phase of mammalian melanogenesis. The role of dopachrome tautomerase and the ratio between 5,6-dihydroxyindole-2-carboxylic acid and 5,6-dihydroxyindole

artículo científico publicado el 15 de agosto de 1992

Regulation of the murine silver locus product (gp87) by the hypopigmenting cytokines TGF-beta1 and TNF-alpha

scientific article published on 01 April 2000

Regulation of tyrosine hydroxylase levels and activity and Fos expression during opioid withdrawal in the hypothalamic PVN and medulla oblongata catecholaminergic cell groups innervating the PVN.

artículo científico publicado en 2003

SOX9 and the tanning response: something new under the sun

scientific article published on 01 February 2008

Selective labeling of alpha-bungarotoxin with fluorescein isothiocyanate and its use for the study of toxin-acetylcholine receptor interactions

scientific article published on 01 December 1990

Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.

artículo científico publicado en 2010

Sticky fingers at work: palmitoylation-dependent MC1R activation

artículo científico publicado en 2017

The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase

artículo científico publicado en 2001

The DHICA oxidase activity of the melanosomal tyrosinases LEMT and HEMT

scientific article published on 01 October 1994

The Pro162 variant is a loss-of-function mutation of the human melanocortin 1 receptor gene

scientific article published on 01 July 2001

The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis.

artículo científico publicado en 2013

The melanogenic system of Xenopus laevis

artículo científico publicado en 1998

The mouse silver locus encodes a single transcript truncated by the silver mutation.

artículo científico publicado en 1999

Thr40 and Met122 are new partial loss-of-function natural mutations of the human melanocortin 1 receptor.

artículo científico publicado en 2001

Tyrosinase isoenzymes in mammalian melanocytes. 1. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma

artículo científico publicado en 1993

Tyrosinase isoenzymes in mammalian melanocytes. 2. Differential activation by alpha-melanocyte-stimulating hormone

artículo científico publicado en 1993

Tyrosinase isoenzymes: two melanosomal tyrosinases with different kinetic properties and susceptibility to inhibition by calcium

scientific article published on 01 October 1994

alpha-Melanotropin immunoreactivity in human melanoma exudate is related to necrosis.

artículo científico publicado en 1998

cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage

article

Lista de obras de José C García-Borrón

A new spectrophotometric assay for dopachrome tautomerase

A three-dimensional model of mammalian tyrosinase active site accounting for loss of function mutations

Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady-state retention of mutant forms in the proximal golgi

After dopachrome

Agonist-independent, high constitutive activity of the human melanocortin 1 receptor.

Alpha-MSH and other melanogenic activators mediate opposite effects on tyrosinase and dopachrome tautomerase in B16/F10 mouse melanoma cells

Anti-inflammatory and anti-invasive effects of α-melanocyte-stimulating hormone in human melanoma cells ⬇️

Apoptosis and molecular pathways in the seminiferous epithelium of aged and photoinhibited Syrian hamsters (Mesocricetus auratus).

Association of Melanocortin-1 Receptor Variants with Pigmentary Traits in Humans: A Pooled Analysis from the M-Skip Project ⬇️

Comparative action of dopachrome tautomerase and metal ions on the rearrangement of dopachrome

Comparison of TRPs from murine and human malignant melanocytes

Conformational studies of soluble and immobilized frog epidermis tyrosinase by fluorescence

Conjugation with Dihydrolipoic Acid Imparts Caffeic Acid Ester Potent Inhibitory Effect on Dopa Oxidase Activity of Human Tyrosinase

Differential and competitive regulation of human melanocortin 1 receptor signaling by β-arrestin isoforms ⬇️

Dopachrome tautomerase decreases the binding of indolic melanogenesis intermediates to proteins

Effect of detergents and endogenous lipids on the activity and properties of tyrosinase and its related proteins

Elevated glucocorticoid levels are responsible for induction of tyrosine hydroxylase mRNA expression, phosphorylation, and enzyme activity in the nucleus of the solitary tract during morphine withdrawal

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor.

Functional interplay between secreted ligands and receptors in melanoma

Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.

Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase.

Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients.

Identification and functional characterization of natural human melanocortin 1 receptor mutant alleles in Pakistani population.

Identification of active site residues involved in metal cofactor binding and stereospecific substrate recognition in Mammalian tyrosinase. Implications to the catalytic cycle.

Improved tyrosinase activity stains in polyacrylamide electrophoresis gels

Incorporation of bovine thyroid peroxidase in liposomes

Is dopachrome tautomerase necessary to get DHICA from dopachrome?

Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function.

MC1R signaling. Intracellular partners and pathophysiological implications

MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project. ⬇️

MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas

Melanocortin 1 receptor and skin pathophysiology: beyond colour, much more than meets the eye

Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology.

Melanocortin-1 receptor structure and functional regulation.

Melanocortin-1 receptor, skin cancer and phenotypic characteristics (M-SKIP) project: study design and methods for pooling results of genetic epidemiological studies ⬇️

Melanocyte stimulating hormone activation of tyrosinase in B16 mouse melanoma cells. Evidence for a differential induction of two distinct isoenzymes

Molecular anatomy of tyrosinase and its related proteins: beyond the histidine-bound metal catalytic center.

Molecular basis of the extreme dilution mottled mouse mutation: a combination of coding and noncoding genomic alterations

Molecular interactions within the melanogenic complex: formation of heterodimers of tyrosinase and TRP1 from B16 mouse melanoma

New insights on the structure of the mouse silver locus and on the function of the silver protein

N‐glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role ⬇️

Partial characterization of IR-alpha-MSH peptides found in melanoma tumors

Preparation of purified tyrosinase devoid of dopachrome tautomerase from mammalian malignant melanocytes

Quantitative determination of tryptophanyl and tyrosyl residues of proteins by second-derivative fluorescence spectroscopy

Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer

Regulation of mammalian melanogenesis. I: Partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase

Regulation of mammalian melanogenesis. II: The role of metal cations

Regulation of the cytosolic and melanosome-bound tyrosinase activities in Harding-Passey mouse melanoma

Regulation of the final phase of mammalian melanogenesis. The role of dopachrome tautomerase and the ratio between 5,6-dihydroxyindole-2-carboxylic acid and 5,6-dihydroxyindole

Regulation of the murine silver locus product (gp87) by the hypopigmenting cytokines TGF-beta1 and TNF-alpha

Regulation of tyrosine hydroxylase levels and activity and Fos expression during opioid withdrawal in the hypothalamic PVN and medulla oblongata catecholaminergic cell groups innervating the PVN.

SOX9 and the tanning response: something new under the sun

Selective labeling of alpha-bungarotoxin with fluorescein isothiocyanate and its use for the study of toxin-acetylcholine receptor interactions

Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.

Sticky fingers at work: palmitoylation-dependent MC1R activation

The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase

The DHICA oxidase activity of the melanosomal tyrosinases LEMT and HEMT

The Pro162 variant is a loss-of-function mutation of the human melanocortin 1 receptor gene

The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis.

The melanogenic system of Xenopus laevis

The mouse silver locus encodes a single transcript truncated by the silver mutation.

Thr40 and Met122 are new partial loss-of-function natural mutations of the human melanocortin 1 receptor.

Tyrosinase isoenzymes in mammalian melanocytes. 1. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma

Tyrosinase isoenzymes in mammalian melanocytes. 2. Differential activation by alpha-melanocyte-stimulating hormone

Tyrosinase isoenzymes: two melanosomal tyrosinases with different kinetic properties and susceptibility to inhibition by calcium

alpha-Melanotropin immunoreactivity in human melanoma exudate is related to necrosis.

cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage