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Lista de obras de Silva Hecimovic

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains

artículo científico publicado en 2018

Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

artículo científico publicado en 2010

Cholesterol-dependent energy transfer between fluorescent proteins-insights into protein proximity of APP and BACE1 in different membranes in Niemann-Pick type C disease cells.

artículo científico publicado en 2012

Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells.

artículo científico publicado en 2012

Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes

artículo científico publicado en 2004

Enhanced activity of superoxide dismutase is a common response to dietary and genetically induced increased cholesterol levels

scientific article published on 17 August 2018

Expand Long PCR for fragile X mutation detection.

artículo científico publicado en 1997

GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells.

artículo científico publicado en 2014

Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins

artículo científico publicado en 2016

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia

artículo científico publicado en 2021

Mutations in APP have independent effects on Abeta and CTFgamma generation

artículo científico publicado en 2004

N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick Type C disease model cells.

artículo científico publicado en 2018

Nano-HPLC-MS analysis of phospholipids in cerebrospinal fluid of Alzheimer's disease patients--a pilot study

artículo científico publicado en 2010

Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathway

artículo científico publicado en 2010

With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions

artículo científico publicado en 2016