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Lista de obras de Helen M Roche

A Conjugated Linoleic Acid-Enriched Beef Diet Attenuates Lipopolysaccharide-Induced Inflammation in Mice in Part through PPARγ-Mediated Suppression of Toll-Like Receptor 4

scientific article published on 21 October 2009

A Low-Fat, High-Complex Carbohydrate Diet Supplemented with Long-Chain (n-3) Fatty Acids Alters the Postprandial Lipoprotein Profile in Patients with Metabolic Syndrome

artículo científico publicado en 2010

A Period 2 genetic variant interacts with plasma SFA to modify plasma lipid concentrations in adults with metabolic syndrome.

artículo científico publicado en 2012

A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome-mediated inflammation and improving insulin signaling

artículo científico publicado en 2016

A gene variation (rs12691) in the CCAT/enhancer binding protein α modulates glucose metabolism in metabolic syndrome.

artículo científico publicado en 2012

A low-fat high-carbohydrate diet supplemented with long-chain n-3 PUFA reduces the risk of the metabolic syndrome

artículo científico publicado en 2011

ACC2 gene polymorphisms, metabolic syndrome, and gene-nutrient interactions with dietary fat.

artículo científico publicado en 2010

APOE genotype influences insulin resistance, apolipoprotein CII and CIII according to plasma fatty acid profile in the Metabolic Syndrome

artículo científico publicado en 2017

Acute-on-chronic effects of fatty acids on intestinal triacylglycerol-rich lipoprotein metabolism

artículo científico publicado en 2002

Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components

artículo científico publicado en 2010

Adipose tissue dysregulation and metabolic consequences in childhood and adolescent obesity: potential impact of dietary fat quality

artículo científico publicado en 2014

Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome.

artículo científico publicado en 2012

Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages.

artículo científico publicado en 2009

Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue

artículo científico publicado en 2007

Antioxidant system response is modified by dietary fat in adipose tissue of metabolic syndrome patients.

artículo científico publicado en 2013

Association of the tumor necrosis factor-alpha promoter polymorphism with change in triacylglycerol response to sequential meals

artículo científico publicado en 2016

Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet.

artículo científico publicado en 2009

Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome

artículo científico publicado en 2010

Body mass index mediates inflammatory response to acute dietary challenges

artículo científico publicado en 2015

Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome.

artículo científico publicado en 2011

Chronic but not acute conjugated linoleic acid treatment inhibits deoxycholic acid-induced protein kinase C and nuclear factor-kappaB activation in human colorectal cancer cells

artículo científico publicado en 2006

Cis-9, trans-11-conjugated linoleic acid but not its precursor trans-vaccenic acid attenuate inflammatory markers in the human colonic epithelial cell line Caco-2.

artículo científico publicado en 2008

Clustering high-dimensional mixed data to uncover sub-phenotypes: joint analysis of phenotypic and genotypic data.

artículo científico publicado en 2017

Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance

artículo científico publicado en 2017

Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome

article

Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages

artículo científico publicado en 2004

Conjugated linoleic acid supplementation reduces peripheral blood mononuclear cell interleukin-2 production in healthy middle-aged males

scientific article published on 21 March 2007

Conjugated linoleic acid suppresses dendritic cell activation and subsequent Th17 responses

article

Conjugated linoleic acid: a functional nutrient in the different pathophysiological components of the metabolic syndrome?

artículo científico publicado en 2006

Diet and Metabolic Syndrome: An Overview

artículo científico publicado en 2013

Dietary Saturated Fat Modulates the Association between STAT3 Polymorphisms and Abdominal Obesity in Adults

scientific article published on 23 September 2009

Dietary carbohydrates and triacylglycerol metabolism.

artículo científico publicado en 1999

Dietary fat differentially influences regulatory endothelial function during the postprandial state in patients with metabolic syndrome: from the LIPGENE study.

artículo científico publicado en 2009

Dietary fat differentially influences the lipids storage on the adipose tissue in metabolic syndrome patients.

artículo científico publicado en 2013

Dietary fat may modulate adipose tissue homeostasis through the processes of autophagy and apoptosis.

artículo científico publicado en 2016

Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study

artículo científico publicado en 2010

Dietary fat modifies lipid metabolism in the adipose tissue of metabolic syndrome patients.

artículo científico publicado en 2014

Dietary fat modifies the postprandial inflammatory state in subjects with metabolic syndrome: the LIPGENE study.

artículo científico publicado en 2012

Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome.

artículo científico publicado en 2017

Dietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome risk

article by Catherine M. Phillips et al published February 2012 in Atherosclerosis

Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers

artículo científico publicado en 2014

Dietary lipids and gene expression.

artículo científico publicado en 2004

Dietary saturated fat, gender and genetic variation at the TCF7L2 locus predict the development of metabolic syndrome

artículo científico publicado en 2011

Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance.

artículo científico publicado en 2012

Differences in postprandial lipaemic response between Northern and Southern Europeans.

artículo científico publicado en 1998

Discriminating dietary responses by combining transcriptomics and metabolomics data in nutrition intervention studies

artículo científico publicado en 2020

Divergent effects of a CLA-enriched beef diet on metabolic health in ApoE-/- and ob/ob mice.

artículo científico publicado en 2012

Divergent mechanisms of cis9, trans11-and trans10, cis12-conjugated linoleic acid affecting insulin resistance and inflammation in apolipoprotein E knockout mice: a proteomics approach.

artículo científico publicado en 2005

Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA.

artículo científico publicado en 2011

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.

artículo científico publicado en 2006

Effect of Dietary Lipids on Endotoxemia Influences Postprandial Inflammatory Response.

artículo científico publicado en 2017

Effect of dietary fat modification on subcutaneous white adipose tissue insulin sensitivity in patients with metabolic syndrome

artículo científico publicado en 2014

Effect of dietary supplementation with conjugated linoleic acid on markers of calcium and bone metabolism in healthy adult men.

artículo científico publicado en 2005

Effect of long-term olive oil dietary intervention on postprandial triacylglycerol and factor VII metabolism

scientific article published on 01 September 1998

Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome—LIPGENE: a European randomized dietary intervention study

artículo científico publicado en 2010

Effects of dietary fat modification on oxidative stress and inflammatory markers in the LIPGENE study

artículo científico publicado en 2010

Effects of dietary fat modification on skeletal muscle fatty acid handling in the metabolic syndrome.

artículo científico publicado en 2010

Effects of dietary fat on insulin secretion in subjects with the metabolic syndrome

scientific article published on 01 May 2019

Effects of rs7903146 variation in the Tcf7l2 gene in the lipid metabolism of three different populations

artículo científico publicado en 2012

Effects of the Mediterranean Diet Supplemented With Coenzyme Q10 on Metabolomic Profiles in Elderly Men and Women

artículo científico publicado en 2014

Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells

artículo científico publicado en 2006

Elevated Tumor Expression of PAI-1 and SNAI2 in Obese Esophageal Adenocarcinoma Patients and Impact on Prognosis

artículo científico publicado en 2012

Endogenous Oils Derived From Human Adipocytes Are Potent Adjuvants That Promote IL-1α–Dependent Inflammation

scientific article published on 23 January 2014

Endoplasmic reticulum stress in adipose tissue determines postprandial lipoprotein metabolism in metabolic syndrome patients

artículo científico publicado en 2013

Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach

artículo científico publicado en 2017

Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue.

artículo científico

Fatty Acids and NLRP3 Inflammasome-Mediated Inflammation in Metabolic Tissues

artículo científico

Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome

artículo científico publicado en 2016

Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells

artículo científico publicado en 2001

Fatty acids and the metabolic syndrome

artículo científico publicado en 2005

Gene-nutrient interactions and gender may modulate the association between ApoA1 and ApoB gene polymorphisms and metabolic syndrome risk

artículo científico publicado en 2010

Gene-nutrient interactions in the metabolic syndrome

artículo científico publicado en 2008

Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1interact with plasma saturated fatty acids to modulate insulin resistance

article

Gene-nutrient interactions on the phosphoenolpyruvate carboxykinase influence insulin sensitivity in metabolic syndrome subjects

artículo científico publicado en 2012

Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome

artículo científico publicado en 2010

Genetic and nutrient determinants of the metabolic syndrome

artículo científico publicado en 2006

Genetic variations at the lipoprotein lipase gene influence plasma lipid concentrations and interact with plasma n-6 polyunsaturated fatty acids to modulate lipid metabolism

artículo científico publicado en 2011

Glucokinase regulatory protein genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome

artículo científico publicado en 2011

Habitual dietary intake impacts on the lipidomic profile.

artículo científico publicado en 2014

High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults

artículo científico publicado en 2012

High-Density Lipoprotein Proteomic Composition, and not Efflux Capacity, Reflects Differential Modulation of Reverse Cholesterol Transport by Saturated and Monounsaturated Fat Diets

article

High-molecular-weight adiponectin is selectively reduced in women with polycystic ovary syndrome independent of body mass index and severity of insulin resistance.

artículo científico publicado en 2010

Hormonal and metabolic effects of polyunsaturated fatty acids in young women with polycystic ovary syndrome: results from a cross-sectional analysis and a randomized, placebo-controlled, crossover trial

artículo científico publicado en 2011

Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort.

artículo científico publicado en 2017

Identification of differential responses to an oral glucose tolerance test in healthy adults

artículo científico publicado en 2013

Impact of anti-inflammatory nutrients on obesity-associated metabolic-inflammation from childhood through to adulthood

artículo científico publicado en 2016

Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome

artículo científico publicado en 2012

Impact of geographical region on urinary metabolomic and plasma fatty acid profiles in subjects with the metabolic syndrome across Europe: the LIPGENE study

artículo científico publicado en 2013

Impact of leucine on energy balance

artículo científico

Increased levels of microparticles originating from endothelial cells, platelets and erythrocytes in subjects with metabolic syndrome: Relationship with oxidative stress

scientific article published on 15 April 2010

Influence of endothelial dysfunction on telomere length in subjects with metabolic syndrome: LIPGENE study

artículo científico publicado en 2014

Insights into the role of macrophage migration inhibitory factor in obesity and insulin resistance

artículo científico

Insulin receptor substrate-2 gene variants in subjects with metabolic syndrome: association with plasma monounsaturated and n-3 polyunsaturated fatty acid levels and insulin resistance.

artículo científico publicado en 2011

Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study.

artículo científico publicado en 2015

Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice

artículo científico publicado en 2012

Interactions between differential fatty acids and inflammatory stressors-impact on metabolic health

artículo científico publicado en 2014

Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.

artículo científico publicado en 2009

Intermittent hypoxia in obstructive sleep apnoea mediates insulin resistance through adipose tissue inflammation

artículo científico publicado en 2017

Isomer-dependent metabolic effects of conjugated linoleic acid: insights from molecular markers sterol regulatory element-binding protein-1c and LXRalpha

artículo científico publicado en 2002

LIPGENE food-exchange model for alteration of dietary fat quantity and quality in free-living participants from eight European countries.

artículo científico publicado en 2008

LPS induced tissue factor expression in the THP-1 monocyte cell line is attenuated by conjugated linoleic acid

artículo científico publicado en 2006

Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis.

artículo científico publicado en 2011

Leptin Receptor Polymorphisms Interact with Polyunsaturated Fatty Acids to Augment Risk of Insulin Resistance and Metabolic Syndrome in Adults

scholarly article by Catherine M. Phillips et al published 23 December 2009 in Journal of Nutrition

Lipoprotein profile, plasma ischemia modified albumin and LDL density change in the course of postprandial lipemia. Insights from the LIPGENE study

artículo científico publicado en 2010

Lipoprotein subclass patterns in women with polycystic ovary syndrome (PCOS) compared with equally insulin-resistant women without PCOS.

artículo científico publicado en 2010

Lipoxin A4 attenuates adipose inflammation

artículo científico publicado en 2012

Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice.

artículo científico publicado en 2013

Low-grade inflammation, diet composition and health: current research evidence and its translation

artículo científico publicado en 2015

Macrophage migration inhibitory factor deficiency ameliorates high-fat diet induced insulin resistance in mice with reduced adipose inflammation and hepatic steatosis

artículo científico publicado en 2014

Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies

artículo científico publicado en 2013

Mediterranean Diet, Glucose Homeostasis and Inflammasome Genetic Variants: The CORDIOPREV Study.

artículo científico publicado en 2018

Metabolic Inflammation-Differential Modulation by Dietary Constituents

artículo científico publicado en 2016

Metabolic and hormonal aspects of polycystic ovary syndrome: the impact of diet

scientific article published on 10 August 2010

Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver

scientific article published on 03 March 2009

Modulation of the lipidomic profile due to a lipid challenge and fitness level: a postprandial study

artículo científico publicado en 2015

Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.

artículo científico publicado en 2015

NOS3 gene polymorphisms are associated with risk markers of cardiovascular disease, and interact with omega-3 polyunsaturated fatty acids

article

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice

article

Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy

artículo científico publicado en 2012

Nutrigenomics—new approaches for human nutrition research

Nutritional Modulation of AMPK-Impact upon Metabolic-Inflammation

artículo científico publicado en 2018

Nutritional aspects of metabolic inflammation in relation to health--insights from transcriptomic biomarkers in PBMC of fatty acids and polyphenols

artículo científico publicado en 2014

Nutritional modulation of metabolic inflammation

artículo científico publicado en 2017

Nutritional status, genetic susceptibility, and insulin resistance--important precedents to atherosclerosis.

artículo científico

Obesity and Body Fat Classification in the Metabolic Syndrome: Impact on Cardiometabolic Risk Metabotype

scholarly article by Catherine M. Phillips et al published 28 June 2012 in Obesity

Obesity and Insulin Resistance Are the Main Determinants of Postprandial Lipoprotein Dysmetabolism in Polycystic Ovary Syndrome

artículo científico publicado en 2016

Obesity and body fat classification in the metabolic syndrome: Impact on cardiometabolic risk metabotype

artículo científico publicado en 2013

Omega-3 fatty acid concentrate decreased triglycerides in coronary heart disease patients treated with simvastatin

Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ

artículo científico publicado en 2010

Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study.

artículo científico publicado en 2013

PBMCs reflect the immune component of the WAT transcriptome--implications as biomarkers of metabolic health in the postprandial state

artículo científico publicado en 2013

Peripheral blood mononuclear cells as in vivo model for dietary intervention induced systemic oxidative stress

artículo científico publicado en 2014

Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study.

artículo científico publicado en 2010

Postprandial changes in the proteome are modulated by dietary fat in patients with metabolic syndrome

artículo científico publicado en 2012

Postprandial inflammatory response in adipose tissue of patients with metabolic syndrome after the intake of different dietary models

scientific article published on 01 December 2011

Postprandial oxidative stress is modified by dietary fat: evidence from a human intervention study

artículo científico publicado en 2010

Postprandial triacylglycerolaemia--nutritional implications.

artículo científico publicado en 1995

Prediction of the metabolic syndrome status based on dietary and genetic parameters, using Random Forest

artículo científico publicado en 2008

Processed red meat contribution to dietary patterns and the associated cardio-metabolic outcomes.

artículo científico publicado en 2017

Profound resolution of early atherosclerosis with conjugated linoleic acid.

artículo científico publicado en 2005

Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice

artículo científico publicado en 2017

Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL/6J mice.

artículo científico publicado en 2014

Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids.

artículo científico publicado en 2015

Regression of pre-established atherosclerosis in the apoE−/− mouse by conjugated linoleic acid ⬇️

artículo científico publicado el 1 de octubre de 2003

Relationship between the lipidome, inflammatory markers and insulin resistance

artículo científico publicado en 2014

Selective effect of conjugated linoleic acid isomers on atherosclerotic lesion development in apolipoprotein E knockout mice

artículo científico publicado en 2006

Serum vitamin D concentration does not predict insulin action or secretion in European subjects with the metabolic syndrome

artículo científico publicado en 2010

Session 2: Personalised nutrition. Transcriptomic signatures that have identified key features of metabolic syndrome

artículo científico publicado en 2008

Sexual Dimorphism, Age, and Fat Mass Are Key Phenotypic Drivers of Proteomic Signatures

artículo científico publicado en 2017

Skeletal muscle fatty acid handling in insulin resistant men.

artículo científico publicado en 2011

Substitution of dietary monounsaturated fatty acids for saturated fatty acids in a free-living population: a feasibility study

The Lipgene Food-Exchange Model: a tool to enable investigation of four diets distinct in fatty acid composition.

artículo científico publicado en 2008

The SGBS cell strain as a model for the in vitro study of obesity and cancer

artículo científico publicado en 2012

The challenges for molecular nutrition research 4: the "nutritional systems biology level".

artículo científico publicado en 2008

The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects

artículo científico publicado en 2002

The effect of low-dose fish oil supplementation on serum growth factors in healthy humans

artículo científico publicado en 2000

The effect of test meal monounsaturated fatty acid: saturated fatty acid ratio on postprandial lipid metabolism.

artículo científico publicado en 1998

The effect of the plasma n-3/n-6 polyunsaturated fatty acid ratio on the dietary LDL phenotype transformation - insights from the LIPGENE study

artículo científico

The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers.

artículo científico publicado en 2005

The metabolic syndrome: the crossroads of diet and genetics

artículo científico publicado en 2005

The potential role of olive oil-derived MUFA in insulin sensitivity

artículo científico publicado en 2007

The relationship between BMI and metabolomic profiles: a focus on amino acids

artículo científico

The relationship between aerobic fitness level and metabolic profiles in healthy adults

artículo científico publicado en 2013

The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA.

artículo científico publicado en 2010

Thermolabile methylenetetrahydrofolate reductase (C677T): frequency in the Irish population.

artículo científico publicado en 2002

Top single nucleotide polymorphisms affecting carbohydrate metabolism in metabolic syndrome: from the LIPGENE study

artículo científico publicado en 2013

Transcriptional Metabolic Inflexibility in Skeletal Muscle Among Individuals With Increasing Insulin Resistance

scholarly article by Anneke Jans et al published 23 June 2011 in Obesity

Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health

artículo científico publicado en 2011

Uncovering Factors Related to Pancreatic Beta-Cell Function

artículo científico publicado en 2016

Weighted Gene Co-Expression Network Analysis Identifies Gender Specific Modules and Hub Genes Related to Metabolism and Inflammation in Response to an Acute Lipid Challenge

artículo científico publicado en 2017

Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes

artículo científico publicado en 2013

Within-person variation in the postprandial lipemic response of healthy adults

artículo científico publicado en 2013

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