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Lista de obras de Pierre Dourlen

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

artículo científico publicado en 2016

Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models

artículo científico publicado en 2017

Drosophila fatty acid transport protein regulates rhodopsin-1 metabolism and is required for photoreceptor neuron survival.

artículo científico publicado en 2012

Drosophila models of tauopathies: what have we learned?

artículo científico publicado en 2012

Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

artículo científico publicado en 2012

ER stress inhibits neuronal death by promoting autophagy

artículo científico publicado en 2012

ER stress protects from retinal degeneration

artículo científico publicado en 2009

Fatty acid transport proteins in disease: New insights from invertebrate models

artículo científico

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.

artículo científico publicado en 2016

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

artículo científico publicado en 2016

Identification of Tau Toxicity Modifiers in the Drosophila Eye.

artículo científico publicado en 2017

In vivo assessment of neuronal cell death in Drosophila.

artículo científico publicado en 2015

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

artículo científico publicado en 2013

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

article

Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina

scientific article published on 10 September 2018

Pin1 allows for differential Tau dephosphorylation in neuronal cells

artículo científico publicado en 2006

TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila

artículo científico publicado en 2013

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

artículo científico publicado en 2012

Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domain

artículo científico publicado en 2015

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

artículo científico publicado en 2022

The Tomato/GFP-FLP/FRT method for live imaging of mosaic adult Drosophila photoreceptor cells

artículo científico publicado en 2013

The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis?

artículo científico publicado en 2019

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

scientific journal article

Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila

artículo científico publicado en 2011

Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals