Lista de obras - Cinzia Tesauro - Dominio Público Uruguay

A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism.

artículo científico publicado en 2013

Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study

artículo científico publicado en 2017

Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin

artículo científico publicado en 2009

Decreased camptothecin sensitivity of the stem-cell-like fraction of Caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I

artículo científico publicado en 2014

Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement

artículo científico publicado en 2012

Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I.

artículo científico publicado en 2010

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

artículo científico publicado en 2009

Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX

artículo científico publicado en 2022

Interaction between natural compounds and human topoisomerase I.

artículo científico publicado en 2012

Isolation of functional mitochondria by inertial microfluidics – a new method to sort intracellular organelles from a small scale biological sample

scholarly article in RSC Advances, vol. 7 no. 38, 2017

Microfluidics-Enabled Enzyme Activity Measurement in Single Cells

artículo científico publicado en 2015

Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico

artículo científico publicado en 2013

Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation

artículo científico publicado en 2015

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

artículo científico publicado en 2014

On-slide detection of enzymatic activities in selected single cells.

artículo científico publicado en 2017

Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene.

artículo científico publicado en 2015

Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate.

artículo científico publicado en 2018

Refined Method for Droplet Microfluidics-Enabled Detection of Plasmodium falciparum Encoded Topoisomerase I in Blood from Malaria Patients

artículo científico publicado en 2015

Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant

artículo científico publicado en 2013

Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin

artículo científico publicado en 2012

Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads

artículo científico publicado en 2014

Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification

artículo científico publicado en 2012

Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity.

artículo científico publicado en 2016

The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance

scientific article published on 14 January 2019

The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation.

artículo científico publicado en 2013

Lista de obras de Cinzia Tesauro

A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism.

Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study

Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin

Decreased camptothecin sensitivity of the stem-cell-like fraction of Caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I

Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement

Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I.

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX

Interaction between natural compounds and human topoisomerase I.

Isolation of functional mitochondria by inertial microfluidics – a new method to sort intracellular organelles from a small scale biological sample

Microfluidics-Enabled Enzyme Activity Measurement in Single Cells

Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico

Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

On-slide detection of enzymatic activities in selected single cells.

Real-Time Label-Free Direct Electronic Monitoring of Topoisomerase Enzyme Binding Kinetics on Graphene.

Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate.

Refined Method for Droplet Microfluidics-Enabled Detection of Plasmodium falciparum Encoded Topoisomerase I in Blood from Malaria Patients

Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant

Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin

Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads

Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification

Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity.

The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance

The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation.