Lista de obras - Daniel Ladant - Dominio Público Uruguay

3'-5' phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo

artículo científico publicado en 2012

A Bacterial Adenylate Cyclase-Based Two-Hybrid System Compatible with Gateway® Cloning

artículo científico publicado en 2018

A Gateway(®) -compatible bacterial adenylate cyclase-based two-hybrid system.

artículo científico publicado en 2013

A Tethered Bilayer Assembled on Top of Immobilized Calmodulin to Mimic Cellular Compartmentalization ⬇️

artículo científico publicado el 20 de abril de 2011

A bacterial two-hybrid system based on a reconstituted signal transduction pathway

artículo científico publicado en 1998

A bacterial two-hybrid system that exploits a cAMP signaling cascade in Escherichia coli

artículo científico publicado en 2000

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins.

artículo científico publicado en 2016

Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli.

artículo científico publicado en 1994

Affinity-based chromatography utilizing genetically engineered proteins. Interaction of Bordetella pertussis adenylate cyclase with calmodulin

scientific article published on 01 March 1988

Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studies

artículo científico publicado en 2014

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

artículo científico publicado en 2006

Analysis of Membrane Protein Interactions with a Bacterial Adenylate Cyclase-Based Two-Hybrid (BACTH) Technique.

artículo científico publicado en 2017

Analysis of MreB interactors in Chlamydia reveals a RodZ homolog but fails to detect an interaction with MraY

artículo científico publicado en 2014

Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay

artículo científico publicado en 2002

Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases.

artículo científico publicado en 2008

Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses

artículo científico publicado en 2014

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy

artículo científico publicado en 2018

Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo.

artículo científico publicado en 2004

Bordetella pertussis adenylate cyclase toxin as a tool to analyze molecular interactions in a bacterial two-hybrid system

artículo científico publicado en 2000

Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayer

scientific article published on 02 December 2013

Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells

scientific article published on 01 January 2000

Bordetella pertussis adenylate cyclase. Purification, characterization, and radioimmunoassay.

artículo científico publicado en 1986

Bordetella pertussis adenylate cyclase: a toxin with multiple talents

scientific article published on 01 April 1993

Calcium and membrane binding properties of bovine neurocalcin delta expressed in Escherichia coli

artículo científico publicado en 1995

Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form

artículo científico publicado en 2014

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

artículo científico publicado en 2018

Calcium-induced Folding of Intrinsically Disordered Repeat-in-Toxin (RTX) Motifs via Changes of Protein Charges and Oligomerization States ⬇️

artículo científico publicado el 15 de marzo de 2011

Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin

artículo científico publicado en 2010

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.

artículo científico publicado en 2017

Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin

artículo científico publicado en 2010

Cell entry and cAMP imaging of anthrax edema toxin

artículo científico publicado en 2006

Characterization of YmgF, a 72-residue inner membrane protein that associates with the Escherichia coli cell division machinery

artículo científico publicado en 2008

Characterization of a beta-galactosidase hybrid protein carrying the catalytic domain of Escherichia coli adenylate cyclase

scientific article published on 01 September 1986

Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin

artículo científico publicado en 2013

Characterization of interactions between inclusion membrane proteins from Chlamydia trachomatis

artículo científico publicado en 2015

Characterization of mutant Bordetella pertussis adenylate cyclase toxins with reduced affinity for calmodulin. Implications for the mechanism of toxin entry into target cells

artículo científico publicado en 1997

Characterization of recombinant Bordetella pertussis adenylate cyclase toxins carrying passenger proteins ⬇️

artículo científico publicado el 1 de diciembre de 2001

Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin.

artículo científico publicado en 2010

Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells.

artículo científico publicado en 1998

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes.

artículo científico publicado en 2018

Correction: Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases.

artículo científico publicado en 2008

Defining Membrane Protein Topology Using pho-lac Reporter Fusions

artículo científico publicado en 2017

Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates.

artículo científico publicado en 2006

Differential mechanisms for calcium-dependent protein/membrane association as evidenced from SPR-binding studies on supported biomimetic membranes.

artículo científico publicado en 2003

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

artículo científico publicado en 2018

Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway.

artículo científico publicado en 1999

Disorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretion

artículo científico publicado en 2014

Editorial: Pathogens and disease special issue ETOX18

scientific article published on 01 March 2019

Efficient display of two enzymes on filamentous phage using an improved signal sequence.

artículo científico publicado en 2003

Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein.

artículo científico publicado en 2005

Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system

scientific article published on 01 September 2007

Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases.

artículo científico publicado en 2004

Estimation of intrinsically disordered protein shape and time-averaged apparent hydration in native conditions by a combination of hydrodynamic methods

scientific article published on 01 January 2012

ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation.

artículo científico publicado en 2014

ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview.

artículo científico publicado en 2017

Exposure to Bordetella pertussis adenylate cyclase toxin affects integrin-mediated adhesion and mechanics in alveolar epithelial cells.

artículo científico publicado en 2017

Expression and characterization of calcium-myristoyl switch proteins.

artículo científico

Human immunodeficiency virus (HIV) type 1 transframe protein can restore activity to a dimerization-deficient HIV protease variant.

artículo científico publicado en 2003

Identification of a region that assists membrane insertion and translocation of the catalytic domain of Bordetella pertussis CyaA toxin.

artículo científico publicado en 2012

In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes

scientific article published on 01 June 1996

In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells

artículo científico publicado en 2002

Insertional mutagenesis of Bordetella pertussis adenylate cyclase ⬇️

artículo científico publicado el 5 de febrero de 1992

Interaction Network among Membrane Proteins Involved in Cell Division as Revealed by Bacterial Two-Hybrid Analysis

scientific article published in 2008

Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain

artículo científico publicado en 2003

Interaction of Bordetella pertussis adenylate cyclase with calmodulin. Identification of two separated calmodulin-binding domains

artículo científico publicado en 1988

Interaction of Calcium withBordetella pertussisAdenylate Cyclase Toxin

scientific article published in Journal of Biological Chemistry

Interaction of Calmodulin with Striatin, a WD-repeat Protein Present in Neuronal Dendritic Spines ⬇️

artículo científico publicado el 28 de agosto de 1998

Lack of MHC class II molecules favors CD8+ T-cell infiltration into tumors associated with an increased control of tumor growth.

artículo científico publicado en 2017

Large-scale study of the interactions between proteins involved in type IV pilus biology in Neisseria meningitidis: characterization of a subcomplex involved in pilus assembly

artículo científico publicado en 2012

Mean net charge of intrinsically disordered proteins: experimental determination of protein valence by electrophoretic mobility measurements.

artículo científico publicado en 2012

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region

artículo científico publicado en 2017

Molecular Motions as a Drug Target: Mechanistic Simulations of Anthrax Toxin Edema Factor Function Led to the Discovery of Novel Allosteric Inhibitors ⬇️

artículo científico publicado el 31 de julio de 2012

Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein.

artículo científico publicado en 2013

Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice

artículo científico publicado en 2011

Post-translational acylation controls the folding and functions of the CyaA RTX toxin

artículo científico publicado en 2019

Protein-Protein Interaction: Bacterial Two-Hybrid.

artículo científico publicado en 2017

Protein-protein interaction between Bacillus stearothermophilus tyrosyl-tRNA synthetase subdomains revealed by a bacterial two-hybrid system.

artículo científico publicado en 2001

Purification and immunological characterization of bacterial and secreted adenylate cyclase of "Bordetella pertussis"

artículo científico publicado en 1986

RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion.

artículo científico publicado en 2008

Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication

artículo científico publicado en 2015

Recombinant adenylate cyclase toxin of Bordetella pertussis induces cytotoxic T lymphocyte responses against HLA*0201-restricted melanoma epitopes.

artículo científico publicado en 2003

Repeat sequences in the Bordetella pertussis adenylate cyclase toxin can be recognized as alternative carboxy-proximal secretion signals by the Escherichia coli alpha-haemolysin translocator.

artículo científico publicado en 1993

Role of leucine zipper motifs in association of the Escherichia coli cell division proteins FtsL and FtsB.

artículo científico publicado en 2011

SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin.

artículo científico publicado en 2017

Sensitive genetic screen for protease activity based on a cyclic AMP signaling cascade in Escherichia coli.

artículo científico publicado en 2000

Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.

artículo científico publicado en 2017

Structural and functional characterization of an essential RTX subdomain of Bordetella pertussis adenylate cyclase toxin.

artículo científico publicado en 2006

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

artículo científico publicado en 2015

Synthesis and characterization of tethered lipid assemblies for membrane protein reconstitution (Review).

artículo científico publicado en 2017

The Adenylate Cyclase (CyaA) Toxin from Has No Detectable Phospholipase A (PLA) Activity In Vitro

artículo científico publicado en 2019

The adenylate cyclase of Bordetella pertussis: a vector to target antigen presenting cells.

artículo científico publicado en 2002

The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)

artículo científico publicado en 2001

The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling

artículo científico publicado en 2009

The effector protein ExoY secreted by Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for GTP.

artículo científico publicado en 2011

The extreme C-terminus of the effector ExoY is crucial for binding to its eukaryotic activator, F-actin

artículo científico publicado en 2018

The β-lactam resistance protein Blr, a small membrane polypeptide, is a component of the Escherichia coli cell division machinery.

artículo científico publicado en 2012

Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T cell epitope

artículo científico publicado en 1999

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis

scientific article published on 01 November 2018

Two-hybrid systems and their usage in infection biology.

artículo científico publicado en 2002

Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor.

artículo científico publicado en 2010

ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics

artículo científico

cAMP assays

artículo científico publicado en 2007

Lista de obras de Daniel Ladant

3'-5' phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo

A Bacterial Adenylate Cyclase-Based Two-Hybrid System Compatible with Gateway® Cloning

A Gateway(®) -compatible bacterial adenylate cyclase-based two-hybrid system.

A Tethered Bilayer Assembled on Top of Immobilized Calmodulin to Mimic Cellular Compartmentalization ⬇️

A bacterial two-hybrid system based on a reconstituted signal transduction pathway

A bacterial two-hybrid system that exploits a cAMP signaling cascade in Escherichia coli

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins.

Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli.

Affinity-based chromatography utilizing genetically engineered proteins. Interaction of Bordetella pertussis adenylate cyclase with calmodulin

Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studies

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

Analysis of Membrane Protein Interactions with a Bacterial Adenylate Cyclase-Based Two-Hybrid (BACTH) Technique.

Analysis of MreB interactors in Chlamydia reveals a RodZ homolog but fails to detect an interaction with MraY

Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay

Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases.

Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy

Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo.

Bordetella pertussis adenylate cyclase toxin as a tool to analyze molecular interactions in a bacterial two-hybrid system

Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayer

Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells

Bordetella pertussis adenylate cyclase. Purification, characterization, and radioimmunoassay.

Bordetella pertussis adenylate cyclase: a toxin with multiple talents

Calcium and membrane binding properties of bovine neurocalcin delta expressed in Escherichia coli

Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

Calcium-induced Folding of Intrinsically Disordered Repeat-in-Toxin (RTX) Motifs via Changes of Protein Charges and Oligomerization States ⬇️

Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.

Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin

Cell entry and cAMP imaging of anthrax edema toxin

Characterization of YmgF, a 72-residue inner membrane protein that associates with the Escherichia coli cell division machinery

Characterization of a beta-galactosidase hybrid protein carrying the catalytic domain of Escherichia coli adenylate cyclase

Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin

Characterization of interactions between inclusion membrane proteins from Chlamydia trachomatis

Characterization of mutant Bordetella pertussis adenylate cyclase toxins with reduced affinity for calmodulin. Implications for the mechanism of toxin entry into target cells

Characterization of recombinant Bordetella pertussis adenylate cyclase toxins carrying passenger proteins ⬇️

Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin.

Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells.

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes.

Correction: Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases.

Defining Membrane Protein Topology Using pho-lac Reporter Fusions

Delivery of the HIV-1 Tat protein to dendritic cells by the CyaA vector induces specific Th1 responses and high affinity neutralizing antibodies in non human primates.

Differential mechanisms for calcium-dependent protein/membrane association as evidenced from SPR-binding studies on supported biomimetic membranes.

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin

Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway.

Disorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretion

Editorial: Pathogens and disease special issue ETOX18

Efficient display of two enzymes on filamentous phage using an improved signal sequence.

Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein.

Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system

Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases.

Estimation of intrinsically disordered protein shape and time-averaged apparent hydration in native conditions by a combination of hydrodynamic methods

ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation.

ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview.

Exposure to Bordetella pertussis adenylate cyclase toxin affects integrin-mediated adhesion and mechanics in alveolar epithelial cells.

Expression and characterization of calcium-myristoyl switch proteins.

Human immunodeficiency virus (HIV) type 1 transframe protein can restore activity to a dimerization-deficient HIV protease variant.

Identification of a region that assists membrane insertion and translocation of the catalytic domain of Bordetella pertussis CyaA toxin.

In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes

In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells

Insertional mutagenesis of Bordetella pertussis adenylate cyclase ⬇️

Interaction Network among Membrane Proteins Involved in Cell Division as Revealed by Bacterial Two-Hybrid Analysis

Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain

Interaction of Bordetella pertussis adenylate cyclase with calmodulin. Identification of two separated calmodulin-binding domains

Interaction of Calcium withBordetella pertussisAdenylate Cyclase Toxin

Interaction of Calmodulin with Striatin, a WD-repeat Protein Present in Neuronal Dendritic Spines ⬇️

Lack of MHC class II molecules favors CD8+ T-cell infiltration into tumors associated with an increased control of tumor growth.

Large-scale study of the interactions between proteins involved in type IV pilus biology in Neisseria meningitidis: characterization of a subcomplex involved in pilus assembly

Mean net charge of intrinsically disordered proteins: experimental determination of protein valence by electrophoretic mobility measurements.

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region

Molecular Motions as a Drug Target: Mechanistic Simulations of Anthrax Toxin Edema Factor Function Led to the Discovery of Novel Allosteric Inhibitors ⬇️

Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein.

Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice

Post-translational acylation controls the folding and functions of the CyaA RTX toxin

Protein-Protein Interaction: Bacterial Two-Hybrid.

Protein-protein interaction between Bacillus stearothermophilus tyrosyl-tRNA synthetase subdomains revealed by a bacterial two-hybrid system.

Purification and immunological characterization of bacterial and secreted adenylate cyclase of "Bordetella pertussis"

RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion.