Lista de obras - Wai-Ping Fung-Leung - Dominio Público Uruguay

A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.

artículo científico publicado en 2005

ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism.

artículo científico publicado en 2001

Adoptively transferred CD4+ lymphocytes from CD8 -/- mice are sufficient to mediate the rejection of MHC class II or class I disparate skin grafts

artículo científico publicado en 1996

Altered Antigen Presentation in Mice Lacking H2-O ⬇️

artículo científico publicado el 1 de febrero de 1998

Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo ⬇️

artículo científico publicado el 27 de marzo de 2013

Antigen presentation and T cell development in H2-M-deficient mice

scientific journal article

Behavioral characterization of mice lacking histamine H(3) receptors.

artículo científico publicado en 2002

Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: implications on hypertension.

artículo científico publicado en 2010

Bone morphogenic protein-4 induces endothelial cell apoptosis through oxidative stress-dependent p38MAPK and JNK pathway

artículo científico publicado en 2011

CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice.

artículo científico publicado en 1996

CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule

artículo científico publicado en 1993

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny

artículo científico publicado en 1993

Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1

scientific journal article

Characteristics of fetal thymus-derived T cell receptor gamma delta intestinal intraepithelial lymphocytes

artículo científico publicado en 1994

Chronic black tea extract consumption improves endothelial function in ovariectomized rats

artículo científico publicado en 2015

Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats.

artículo científico publicado en 2012

Cilnidipine, a slow-acting Ca2+ channel blocker, induces relaxation in porcine coronary artery: role of endothelial nitric oxide and [Ca2+]i

artículo científico publicado en 2006

Comparison of RNA-Seq and microarray in transcriptome profiling of activated T cells

artículo científico publicado en 2014

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion

artículo científico publicado en 2006

Defective CD8+ T cell activation and cytolytic function in the absence of LFA-1 cannot be restored by increased TCR signaling

scientific article published on 01 November 1999

Down-regulation of CD8 on mature antigen-reactive T cells as a mechanism of peripheral tolerance

scientific article published on 01 October 1995

Embryonic stem cells and homologous recombination ⬇️

artículo científico publicado el 1 de abril de 1992

Endothelial mediators of the acetylcholine-induced relaxation of the rat femoral artery.

artículo científico publicado en 2006

Endothelium-independent relaxation to raloxifene in porcine coronary artery

artículo científico publicado en 2006

Exploiting CD22 To Selectively Tolerize Autoantibody Producing B-Cells in Rheumatoid Arthritis

scientific article published on 20 March 2019

Gender-biased regulation of human IL-17-producing cells in vitro by peptides corresponding to distinct HLA-DRB1 allele-coded sequences

artículo científico publicado en 2013

Generation of mutant mice lacking surface expression of CD4 or CD8 by gene targeting

scientific article published on 01 April 1992

Generation of mutant mice lacking surface expression of CD4 or CD8 gene targeting.

artículo científico publicado en 1992

Histamine H4 receptor antagonists: the new antihistamines?

artículo científico publicado en 2004

Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells

artículo científico publicado en 2003

Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

artículo científico publicado en 2004

Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model.

artículo científico publicado en 2017

IgE-dependent mast cell activation potentiates airway responses in murine asthma models

artículo científico publicado en 2002

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression ⬇️

artículo científico publicado el 1 de diciembre de 1991

Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor

artículo científico publicado en 2020

Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1.

artículo científico publicado en 1996

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells ⬇️

artículo científico publicado el 15 de noviembre de 1993

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

artículo científico publicado en 1998

Intestinal T cells in CD8 alpha knockout mice and T cell receptor transgenic mice.

artículo científico publicado en 1995

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

artículo científico publicado en 1992

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

artículo científico publicado en 2002

Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells.

artículo científico publicado en 1995

Norepinephrine release from the ischemic heart is greatly enhanced in mice lacking histamine H3 receptors.

artículo científico publicado en 2003

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

scientific journal article

Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats.

artículo científico publicado en 2011

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.

artículo científico publicado en 2014

PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.

artículo científico publicado en 2013

Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner.

artículo científico publicado en 1997

Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen

artículo científico publicado en 1992

Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis

artículo científico publicado en 2016

Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function

artículo científico publicado en 2011

Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease

artículo científico publicado en 2010

Prevention of nitroglycerin tolerance in vitro by T0156, a selective phosphodiesterase type 5 inhibitor.

artículo científico publicado en 2008

RORγt and RORα signature genes in human Th17 cells

artículo científico publicado en 2017

Raloxifene improves vascular reactivity in pressurized septal coronary arteries of ovariectomized hamsters fed cholesterol diet

artículo científico publicado en 2011

Raloxifene modulates pulmonary vascular reactivity in spontaneously hypertensive rats

scientific article published on 01 June 2007

Raloxifene relaxes rat intrarenal arteries by inhibiting Ca2+ influx.

artículo científico publicado en 2005

Raloxifene, tamoxifen and vascular tone.

artículo científico publicado en 2007

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

artículo científico publicado en 1994

Requirement of the CD8+ or CD4+ T lymphocyte subsets for the rejection of lymphoma and fibrosarcoma grafts studied in gene knockout hosts

artículo científico publicado en 1998

T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers

artículo científico publicado en 2017

T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation

artículo científico publicado en 2018

Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.

artículo científico publicado en 2000

Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-life.

artículo científico publicado en 2014

Tepoxalin, a novel immunomodulatory compound, synergizes with CsA in suppression of graft-versus-host reaction and allogeneic skin graft rejection

scientific article published on 01 August 1995

The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes

scientific article published on 01 November 1993

Therapeutically relevant concentrations of raloxifene dilate pressurized rat resistance arteries via calcium-dependent endothelial nitric oxide synthase activation.

artículo científico publicado en 2010

Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells.

artículo científico publicado en 1997

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association

artículo científico publicado en 1993

Use of a human skin-grafted nude mouse model for the evaluation of topical retinoic acid treatment

scientific article published on 01 April 1994

Lista de obras de Wai-Ping Fung-Leung

A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.

ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism.

Adoptively transferred CD4+ lymphocytes from CD8 -/- mice are sufficient to mediate the rejection of MHC class II or class I disparate skin grafts

Altered Antigen Presentation in Mice Lacking H2-O ⬇️

Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo ⬇️

Antigen presentation and T cell development in H2-M-deficient mice

Behavioral characterization of mice lacking histamine H(3) receptors.

Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: implications on hypertension.

Bone morphogenic protein-4 induces endothelial cell apoptosis through oxidative stress-dependent p38MAPK and JNK pathway

CD4-negative cytotoxic T cells with a T cell receptor alpha/beta intermediate expression in CD8-deficient mice.

CD8 is critically involved in lymphocyte activation by a T. brucei brucei-released molecule

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny

Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1

Characteristics of fetal thymus-derived T cell receptor gamma delta intestinal intraepithelial lymphocytes

Chronic black tea extract consumption improves endothelial function in ovariectomized rats

Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats.

Cilnidipine, a slow-acting Ca2+ channel blocker, induces relaxation in porcine coronary artery: role of endothelial nitric oxide and [Ca2+]i

Comparison of RNA-Seq and microarray in transcriptome profiling of activated T cells

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion

Defective CD8+ T cell activation and cytolytic function in the absence of LFA-1 cannot be restored by increased TCR signaling

Down-regulation of CD8 on mature antigen-reactive T cells as a mechanism of peripheral tolerance

Embryonic stem cells and homologous recombination ⬇️

Endothelial mediators of the acetylcholine-induced relaxation of the rat femoral artery.

Endothelium-independent relaxation to raloxifene in porcine coronary artery

Exploiting CD22 To Selectively Tolerize Autoantibody Producing B-Cells in Rheumatoid Arthritis

Gender-biased regulation of human IL-17-producing cells in vitro by peptides corresponding to distinct HLA-DRB1 allele-coded sequences

Generation of mutant mice lacking surface expression of CD4 or CD8 by gene targeting

Generation of mutant mice lacking surface expression of CD4 or CD8 gene targeting.

Histamine H4 receptor antagonists: the new antihistamines?

Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells

Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model.

IgE-dependent mast cell activation potentiates airway responses in murine asthma models

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression ⬇️

Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor

Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1.

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells ⬇️

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

Intestinal T cells in CD8 alpha knockout mice and T cell receptor transgenic mice.

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells.

Norepinephrine release from the ischemic heart is greatly enhanced in mice lacking histamine H3 receptors.

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats.

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.

PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.

Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner.

Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen

Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis

Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function

Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease

Prevention of nitroglycerin tolerance in vitro by T0156, a selective phosphodiesterase type 5 inhibitor.

RORγt and RORα signature genes in human Th17 cells

Raloxifene improves vascular reactivity in pressurized septal coronary arteries of ovariectomized hamsters fed cholesterol diet

Raloxifene modulates pulmonary vascular reactivity in spontaneously hypertensive rats

Raloxifene relaxes rat intrarenal arteries by inhibiting Ca2+ influx.

Raloxifene, tamoxifen and vascular tone.

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

Requirement of the CD8+ or CD4+ T lymphocyte subsets for the rejection of lymphoma and fibrosarcoma grafts studied in gene knockout hosts

T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers

T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation

Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.

Targeting the ion channel Kv1.3 with scorpion venom peptides engineered for potency, selectivity, and half-life.

Tepoxalin, a novel immunomodulatory compound, synergizes with CsA in suppression of graft-versus-host reaction and allogeneic skin graft rejection

The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes

Therapeutically relevant concentrations of raloxifene dilate pressurized rat resistance arteries via calcium-dependent endothelial nitric oxide synthase activation.

Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells.

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association

Use of a human skin-grafted nude mouse model for the evaluation of topical retinoic acid treatment