Filtros de búsqueda

Lista de obras de Sébastien Albrecht

Alkynes as masked ylides: gold-catalysed intermolecular reactions of propargylic carboxylates with sulfides

scientific article published on 24 October 2007

Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.

artículo científico publicado en 2017

Amino-benzosuberone: a novel warhead for selective inhibition of human aminopeptidase-N/CD13

artículo científico publicado en 2011

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

artículo científico publicado en 2018

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

scientific article published in Nature

Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma brucei

artículo científico publicado en 2015

Exploring S1 plasticity and probing S1' subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors

artículo científico publicado en 2015

Gold- or platinum-catalyzed synthesis of sulfur heterocycles: access to sulfur ylides without using sacrificial functionality

artículo científico publicado en 2009

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

artículo científico publicado en 2018

Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis.

artículo científico publicado en 2017

Rapid and efficient synthesis of a novel series of substituted aminobenzosuberone derivatives as potent, selective, non-peptidic neutral aminopeptidase inhibitors

artículo científico publicado en 2012

Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo

artículo científico publicado en 2017

Synthesis and structure activity relationships of novel non-peptidic metallo-aminopeptidase inhibitors

artículo científico publicado en 2006

Synthesis of amino-hydroxy-benzocycloheptenones as potent, selective, non-peptidic dinuclear zinc metalloaminopeptidase inhibitors.

artículo científico publicado en 2013