Lista de obras - Haruhisa Kikuchi - Dominio Público Uruguay

1-Methyl-2-undecyl-4(1H)-quinolone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-1.

artículo científico publicado en 2016

5,19-cyclo-9beta,10xi-androstane-3,17-dione promotes neurotrophic factor biosynthesis in 1321N1 human astrocytoma cells and improves passive avoidance learning impairment.

artículo científico publicado en 2007

A novel carbon skeletal trichothecane, tenuipesine A, isolated from an entomopathogenic fungus, Paecilomyces tenuipes.

artículo científico publicado en 2004

A phytoceramide analog stimulates the production of chemokines through CREB activation in human endothelial cells.

artículo científico publicado en 2011

Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells.

artículo científico publicado en 2016

Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans.

artículo científico publicado en 2016

An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes

artículo científico publicado en 2019

Anti-leukemic activities of Dictyostelium secondary metabolites: a novel aromatic metabolite, 4-methyl-5-n-pentylbenzene-1,3-diol, isolated from Dictyostelium mucoroides suppresses cell growth in human leukemia K562 and HL-60 cells

artículo científico publicado en 2006

Antimicrobial Activities of Dictyostelium Differentiation-Inducing Factors and Their Derivatives

artículo científico publicado en 2019

Antimicrobial and antioxidant properties of methanol extract, fractions and compounds from the stem bark of Entada abyssinica Stend ex A. Satabie

artículo científico publicado en 2011

Antimycobacterial flavonoids from the leaf extract of Galenia africana

artículo científico publicado en 2009

Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.

artículo científico publicado en 2012

Artificial compounds differentially control Dictyostelium chemotaxis and cell differentiation

scientific article published on 19 January 2011

Atg1 allows second-signaled autophagic cell death in Dictyostelium ⬇️

artículo científico publicado el 1 de mayo de 2011

Autophagic or necrotic cell death triggered by distinct motifs of the differentiation factor DIF-1.

artículo científico publicado en 2008

Biological Activities of Novel Derivatives of Differentiation-Inducing Factor 3 from Dictyostelium discoideum.

artículo científico publicado en 2017

Biological activities of novel derivatives of DIF-1 isolated from Dictyostelium.

artículo científico publicado en 2008

Construction of a Meroterpenoid-like Compounds Library Based on Diversity-Enhanced Extracts

artículo científico publicado en 2018

Correction to "Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons"

artículo científico publicado en 2019

Correction: ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor

artículo científico publicado en 2015

Defects in the synthetic pathway prevent DIF-1 mediated stalk lineage specification cascade in the non-differentiating social amoeba, Acytostelium subglobosum.

artículo científico publicado en 2014

Derivatives of Dictyostelium differentiation-inducing factors inhibit lysophosphatidic acid-stimulated migration of murine osteosarcoma LM8 cells

artículo científico publicado en 2015

Derivatives of Dictyostelium differentiation-inducing factors promote mitogen-activated IL-2 production via AP-1 in Jurkat cells ⬇️

artículo científico publicado el 14 de enero de 2011

Derivatives of Dictyostelium discoideum differentiation-inducing factor-3 suppress the activities of Trypanosoma cruzi in vitro and in vivo.

artículo científico publicado en 2013

Design and Synthesis of Structure-Simplified Derivatives of Gonytolide for the Promotion of Innate Immune Responses

artículo científico publicado en 2016

Development of a Terpenoid Alkaloid-like Compound Library Based on the Humulene Skeleton.

artículo científico publicado en 2016

Development of diversity-enhanced extracts of Curcuma zedoaria and their new sesquiterpene-like compounds

artículo científico publicado en 2014

Development of novel DIF-1 derivatives that selectively suppress innate immune responses

artículo científico publicado en 2015

Dictyopyrones, novel alpha-pyronoids isolated from Dictyostelium spp., promote stalk cell differentiation in Dictyostelium discoideum

artículo científico publicado en 2005

Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery

artículo científico publicado en 2018

Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation

scientific article published on 30 September 2019

Effect of brefelamide on proliferation of 1321N1 human astrocytoma cells induced by glial cell line-derived neurotrophic factor.

artículo científico publicado en 2018

Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum.

artículo científico publicado en 2017

Exploitation of the derivatives of Dictyostelium differentiation-inducing factor-1, which promote glucose consumption in mammalian cells.

artículo científico publicado en 2008

Exploration of a new type of antimalarial compounds based on febrifugine.

artículo científico publicado en 2006

Furanodictine A and B: amino sugar analogues produced by cellular slime mold Dictyostelium discoideum showing neuronal differentiation activity

scientific article published on 01 October 2001

Glutathione S-transferase 4 is a putative DIF-binding protein that regulates the size of fruiting bodies in Dictyostelium discoideum.

artículo científico publicado en 2016

Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.

artículo científico publicado en 2016

Halogen-Substituted Derivatives of Dictyostelium Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro

scientific article published on 28 June 2019

Identification of brefelamide as a novel inhibitor of osteopontin that suppresses invasion of A549 lung cancer cells.

artículo científico publicado en 2016

Induction of Osteopontin by Dengue Virus-3 Infection in THP-1 Cells: Inhibition of the Synthesis by Brefelamide and Its Derivative.

artículo científico publicado en 2017

Inhibition of inflammatory-molecule synthesis in THP-1 cells stimulated with phorbol 12-myristate 13-acetate by brefelamide derivatives

scientific article published on 19 August 2019

Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.

artículo científico publicado en 2010

Isolation of a Cyclic Depsipetide, Aspergillicin F, and Synthesis of Aspergillicins with Innate Immune-Modulating Activity

artículo científico publicado en 2015

Isolation, Synthesis, and Biological Activity of Chlorinated Alkylresorcinols from Dictyostelium Cellular Slime Molds

artículo científico publicado en 2017

Labdane-type diterpenes and flavones from Dodonaea viscosa ⬇️

artículo científico publicado el 20 de marzo de 2012

Metarhizin A suppresses cell proliferation by inhibiting cytochrome c oxidase activity.

artículo científico publicado en 2014

Mitochondria are the target organelle of differentiation-inducing factor-3, an anti-tumor agent isolated from Dictyostelium discoideum [corrected]

artículo científico publicado en 2013

Monoterpene Indole Alkaloid-Like Compounds Based on Diversity-Enhanced Extracts of Iridoid-Containing Plants and Their Immune Checkpoint Inhibitory Activity

scientific article published on 10 November 2016

Novel acyl alpha-pyronoids, dictyopyrone A, B, and C, from Dictyostelium cellular slime molds

artículo científico publicado en 2000

Novel chlorinated dibenzofurans isolated from the cellular slime mold, Polysphondylium filamentosum, and their biological activities.

artículo científico publicado en 2013

Novel spirocyclic trichothecanes, spirotenuipesine A and B, isolated from entomopathogenic fungus, Paecilomyces tenuipes.

artículo científico publicado en 2004

Oral administration of Dictyostelium differentiation-inducing factor 1 lowers blood glucose levels in streptozotocin-induced diabetic rats

artículo científico publicado en 2016

Peltophorum africanum, a traditional South African medicinal plant, contains an anti HIV-1 constituent, betulinic acid

artículo científico publicado en 2009

Potent antimalarial febrifugine analogues against the plasmodium malaria parasite.

artículo científico publicado en 2002

Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2.

artículo científico publicado en 2016

Preparation of an antibody that recognizes and neutralizes Dictyostelium differentiation-inducing factor-1

artículo científico publicado en 2010

Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum.

artículo científico publicado en 2014

Regulation of IL-2 production in Jurkat cells by Dictyostelium-derived factors.

artículo científico publicado en 2009

Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons

scientific article published on 05 November 2018

Stigmastane derivatives from the roots of Vernonia guineensis and their antimicrobial activity

Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase

artículo científico publicado en 2014

Structural requirements of Dictyostelium differentiation-inducing factors for their stalk-cell-inducing activity in Dictyostelium cells and anti-proliferative activity in K562 human leukemic cells

scientific article published on 01 September 2005

Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007

scientific article published on 03 September 2019

Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis

artículo científico publicado en 2015

Structures of the dimeric and monomeric chromanones, gonytolides A-C, isolated from the fungus Gonytrichum sp. and their promoting activities of innate immune responses.

artículo científico publicado en 2011

Synthesis and innate immunosuppressive effect of 1,2-cyclopentanediol derivatives ⬇️

artículo científico publicado el 3 de febrero de 2011

Synthesis of febrifugine derivatives and development of an effective and safe tetrahydroquinazoline-type antimalarial

scientific article published on 25 January 2014

Synthesis of prenylated quinolinecarboxylic acid derivatives and their anti-obesity activities

artículo científico publicado en 2014

Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis

artículo científico publicado en 2017

The Dictyostelium prestalk inducer DIF-1 directs phosphorylation of a bZIP transcription factor.

artículo científico publicado en 2013

Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds

artículo científico publicado en 2020

Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold

artículo científico publicado en 2015

ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor.

artículo científico publicado en 2014

Lista de obras de Haruhisa Kikuchi

1-Methyl-2-undecyl-4(1H)-quinolone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-1.

5,19-cyclo-9beta,10xi-androstane-3,17-dione promotes neurotrophic factor biosynthesis in 1321N1 human astrocytoma cells and improves passive avoidance learning impairment.

A novel carbon skeletal trichothecane, tenuipesine A, isolated from an entomopathogenic fungus, Paecilomyces tenuipes.

A phytoceramide analog stimulates the production of chemokines through CREB activation in human endothelial cells.

Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells.

Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans.

An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes

Anti-leukemic activities of Dictyostelium secondary metabolites: a novel aromatic metabolite, 4-methyl-5-n-pentylbenzene-1,3-diol, isolated from Dictyostelium mucoroides suppresses cell growth in human leukemia K562 and HL-60 cells

Antimicrobial Activities of Dictyostelium Differentiation-Inducing Factors and Their Derivatives

Antimicrobial and antioxidant properties of methanol extract, fractions and compounds from the stem bark of Entada abyssinica Stend ex A. Satabie

Antimycobacterial flavonoids from the leaf extract of Galenia africana

Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.

Artificial compounds differentially control Dictyostelium chemotaxis and cell differentiation

Atg1 allows second-signaled autophagic cell death in Dictyostelium ⬇️

Autophagic or necrotic cell death triggered by distinct motifs of the differentiation factor DIF-1.

Biological Activities of Novel Derivatives of Differentiation-Inducing Factor 3 from Dictyostelium discoideum.

Biological activities of novel derivatives of DIF-1 isolated from Dictyostelium.

Construction of a Meroterpenoid-like Compounds Library Based on Diversity-Enhanced Extracts

Correction to "Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons"

Correction: ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor

Defects in the synthetic pathway prevent DIF-1 mediated stalk lineage specification cascade in the non-differentiating social amoeba, Acytostelium subglobosum.

Derivatives of Dictyostelium differentiation-inducing factors inhibit lysophosphatidic acid-stimulated migration of murine osteosarcoma LM8 cells

Derivatives of Dictyostelium differentiation-inducing factors promote mitogen-activated IL-2 production via AP-1 in Jurkat cells ⬇️

Derivatives of Dictyostelium discoideum differentiation-inducing factor-3 suppress the activities of Trypanosoma cruzi in vitro and in vivo.

Design and Synthesis of Structure-Simplified Derivatives of Gonytolide for the Promotion of Innate Immune Responses

Development of a Terpenoid Alkaloid-like Compound Library Based on the Humulene Skeleton.

Development of diversity-enhanced extracts of Curcuma zedoaria and their new sesquiterpene-like compounds

Development of novel DIF-1 derivatives that selectively suppress innate immune responses

Dictyopyrones, novel alpha-pyronoids isolated from Dictyostelium spp., promote stalk cell differentiation in Dictyostelium discoideum

Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery

Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation

Effect of brefelamide on proliferation of 1321N1 human astrocytoma cells induced by glial cell line-derived neurotrophic factor.

Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum.

Exploitation of the derivatives of Dictyostelium differentiation-inducing factor-1, which promote glucose consumption in mammalian cells.

Exploration of a new type of antimalarial compounds based on febrifugine.

Furanodictine A and B: amino sugar analogues produced by cellular slime mold Dictyostelium discoideum showing neuronal differentiation activity

Glutathione S-transferase 4 is a putative DIF-binding protein that regulates the size of fruiting bodies in Dictyostelium discoideum.

Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.

Halogen-Substituted Derivatives of Dictyostelium Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro

Identification of brefelamide as a novel inhibitor of osteopontin that suppresses invasion of A549 lung cancer cells.

Induction of Osteopontin by Dengue Virus-3 Infection in THP-1 Cells: Inhibition of the Synthesis by Brefelamide and Its Derivative.

Inhibition of inflammatory-molecule synthesis in THP-1 cells stimulated with phorbol 12-myristate 13-acetate by brefelamide derivatives

Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.

Isolation of a Cyclic Depsipetide, Aspergillicin F, and Synthesis of Aspergillicins with Innate Immune-Modulating Activity

Isolation, Synthesis, and Biological Activity of Chlorinated Alkylresorcinols from Dictyostelium Cellular Slime Molds

Labdane-type diterpenes and flavones from Dodonaea viscosa ⬇️

Metarhizin A suppresses cell proliferation by inhibiting cytochrome c oxidase activity.

Mitochondria are the target organelle of differentiation-inducing factor-3, an anti-tumor agent isolated from Dictyostelium discoideum [corrected]

Monoterpene Indole Alkaloid-Like Compounds Based on Diversity-Enhanced Extracts of Iridoid-Containing Plants and Their Immune Checkpoint Inhibitory Activity

Novel acyl alpha-pyronoids, dictyopyrone A, B, and C, from Dictyostelium cellular slime molds

Novel chlorinated dibenzofurans isolated from the cellular slime mold, Polysphondylium filamentosum, and their biological activities.

Novel spirocyclic trichothecanes, spirotenuipesine A and B, isolated from entomopathogenic fungus, Paecilomyces tenuipes.

Oral administration of Dictyostelium differentiation-inducing factor 1 lowers blood glucose levels in streptozotocin-induced diabetic rats

Peltophorum africanum, a traditional South African medicinal plant, contains an anti HIV-1 constituent, betulinic acid

Potent antimalarial febrifugine analogues against the plasmodium malaria parasite.

Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2.

Preparation of an antibody that recognizes and neutralizes Dictyostelium differentiation-inducing factor-1

Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum.

Regulation of IL-2 production in Jurkat cells by Dictyostelium-derived factors.

Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons

Stigmastane derivatives from the roots of Vernonia guineensis and their antimicrobial activity

Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase

Structural requirements of Dictyostelium differentiation-inducing factors for their stalk-cell-inducing activity in Dictyostelium cells and anti-proliferative activity in K562 human leukemic cells

Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007

Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis

Structures of the dimeric and monomeric chromanones, gonytolides A-C, isolated from the fungus Gonytrichum sp. and their promoting activities of innate immune responses.

Synthesis and innate immunosuppressive effect of 1,2-cyclopentanediol derivatives ⬇️

Synthesis of febrifugine derivatives and development of an effective and safe tetrahydroquinazoline-type antimalarial

Synthesis of prenylated quinolinecarboxylic acid derivatives and their anti-obesity activities

Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis

The Dictyostelium prestalk inducer DIF-1 directs phosphorylation of a bZIP transcription factor.

Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds

Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold

ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor.