Lista de obras - Annette MacLeod - Dominio Público Uruguay

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense

artículo científico publicado en 2016

A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome

artículo científico

A major genetic locus in Trypanosoma brucei is a determinant of host pathology

artículo científico publicado en 2009

A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations

artículo científico publicado en 2017

A protocol to improve genotyping of problematic microsatellite loci of Trypanosoma brucei gambiense from body fluids

artículo científico publicado en 2013

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

artículo científico publicado en 2017

Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis

artículo científico publicado en 2005

Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon

article

Association of APOL1 renal disease risk alleles with Trypanosoma brucei rhodesiense infection outcomes in the northern part of Malawi

scientific article published on 14 August 2019

Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei

artículo científico publicado en 2018

Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea

artículo científico publicado en 2017

Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire

artículo científico publicado en 2017

Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire

article

Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016.

artículo científico publicado en 2017

Characterization of di-, tri-, and tetranucleotide microsatellite markers with perfect repeats for Trypanosoma brucei and related species

artículo científico publicado en 2006

Copy number variation in human genomes from three major ethno-linguistic groups in Africa

artículo científico publicado en 2020

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

artículo científico publicado en 2018

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1

artículo científico publicado en 2011

Differences in pathogenicity and virulence of Trypanosoma brucei gambiense field isolates in experimentally infected Balb/C mice

artículo científico publicado en 2018

Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of co-regulated genes

artículo científico publicado en 2010

Discovery of mating in the major African livestock pathogen Trypanosoma congolense

artículo científico publicado en 2009

Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?

artículo científico publicado en 2018

Evidence of population specific selection inferred from 289 genome sequences of Nilo-Saharan and Niger-Congo linguistic groups in Africa

Exploiting genetic variation to discover genes involved in important disease phenotypes

artículo científico publicado en 2015

Extravascular dermal trypanosomes in suspected and confirmed cases of gambiense Human African Trypanosomiasis

artículo científico publicado en 2020

First evidence that parasite infecting apparent aparasitemic serological suspects in human African trypanosomiasis are Trypanosoma brucei gambiense and are similar to those found in patients

artículo científico publicado en 2011

Genetic analysis of phenotype in Trypanosoma brucei: a classical approach to potentially complex traits

artículo científico publicado en 2002

Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map

artículo científico publicado en 2008

Genetic exchange in Trypanosoma brucei: evidence for mating prior to metacyclic stage development.

artículo científico publicado en 2006

Genome and phylogenetic analyses of trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty

artículo científico publicado en 2015

Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors

artículo científico publicado en 2012

High Levels of Genetic Diversity within Nilo-Saharan Populations: Implications for Human Adaptation

artículo científico publicado en 2020

Human African trypanosomiasis presenting at least 29 years after infection--what can this teach us about the pathogenesis and control of this neglected tropical disease?

artículo científico publicado en 2014

Human and animal Trypanosomes in Côte d'Ivoire form a single breeding population

artículo científico publicado en 2013

Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis

artículo científico publicado en 2017

Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population

scientific article published on 23 March 2019

Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factor

artículo científico publicado en 2010

Multilocus genotyping of Cryptosporidium parvum Type 2: population genetics and sub-structuring

artículo científico publicado en 2003

No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

artículo científico publicado en 2018

No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

scholarly article published 25 August 2017

Novel African trypanocidal agents: membrane rigidifying peptides

artículo científico publicado en 2012

Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection

artículo científico publicado en 2019

Persistently High Incidences of Trypanosoma brucei rhodesiense Sleeping Sickness With Contrasting Focus-Dependent Clinical Phenotypes in Malawi

artículo científico publicado en 2022

Population Genetics and Reproductive Strategies of African Trypanosomes: Revisiting Available Published Data

artículo científico publicado en 2015

Population genetic structure of Guinea Trypanosoma brucei gambiense isolates according to host factors

artículo científico publicado en 2011

Population genetics of Trypanosoma brucei gambiense in sleeping sickness patients with treatment failures in the focus of Mbuji-Mayi, Democratic Republic of the Congo

artículo científico publicado en 2014

Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci

artículo científico publicado en 2013

Population genomics reveals the origin and asexual evolution of human infective trypanosomes

artículo científico publicado en 2016

Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum

artículo científico publicado en 2003

Research capacity. Enabling the genomic revolution in Africa

artículo científico publicado en 2014

Resolving the apparent transmission paradox of African sleeping sickness

article

Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection

artículo científico publicado en 2010

Role of expression site switching in the development of resistance to human Trypanosome Lytic Factor-1 in Trypanosoma brucei brucei

artículo científico publicado en 2011

SNPs in IL4 and IFNG show no protective associations with human African trypanosomiasis in the Democratic Republic of the Congo: a case-control study

scientific article published on 04 August 2020

Spatially and genetically distinct African Trypanosome virulence variants defined by host interferon-gamma response

artículo científico publicado en 2007

T cell activation and the HLA locus associate with latent infections of human African trypanosomiasis

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

artículo científico publicado en 2003

The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense

artículo científico publicado en 2013

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

artículo científico publicado en 2005

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

artículo científico publicado en 2006

The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis

artículo científico publicado en 2010

The plasma membrane of bloodstream-form African trypanosomes confers susceptibility and specificity to killing by hydrophobic peptides

artículo científico publicado en 2010

The population structure of the Cryptosporidium parvum population in Scotland: a complex picture

artículo científico publicado en 2007

The sequence and analysis of Trypanosoma brucei chromosome II.

artículo científico publicado en 2003

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

artículo científico publicado en 2016

To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host

artículo científico publicado en 2020

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

artículo científico publicado en 2013

Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation

artículo científico publicado en 2008

Trypanosoma vivax displays a clonal population structure

artículo científico publicado en 2009

Trypanosome genetics: populations, phenotypes and diversity

artículo científico publicado en 2011

Trypanosome resistance to human innate immunity: targeting Achilles’ heel ⬇️

artículo científico publicado el 8 de octubre de 2012

Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters.

artículo científico publicado en 2007

Whole-genome sequencing of Trypanosoma brucei reveals introgression between subspecies that is associated with virulence

artículo científico publicado en 2013

Lista de obras de Annette MacLeod

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense

A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome

A major genetic locus in Trypanosoma brucei is a determinant of host pathology

A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations

A protocol to improve genotyping of problematic microsatellite loci of Trypanosoma brucei gambiense from body fluids

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis

Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon

Association of APOL1 renal disease risk alleles with Trypanosoma brucei rhodesiense infection outcomes in the northern part of Malawi

Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei

Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea

Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire

Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire

Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016.

Characterization of di-, tri-, and tetranucleotide microsatellite markers with perfect repeats for Trypanosoma brucei and related species

Copy number variation in human genomes from three major ethno-linguistic groups in Africa

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.

Differences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1

Differences in pathogenicity and virulence of Trypanosoma brucei gambiense field isolates in experimentally infected Balb/C mice

Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of co-regulated genes

Discovery of mating in the major African livestock pathogen Trypanosoma congolense

Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?

Evidence of population specific selection inferred from 289 genome sequences of Nilo-Saharan and Niger-Congo linguistic groups in Africa

Exploiting genetic variation to discover genes involved in important disease phenotypes

Extravascular dermal trypanosomes in suspected and confirmed cases of gambiense Human African Trypanosomiasis

First evidence that parasite infecting apparent aparasitemic serological suspects in human African trypanosomiasis are Trypanosoma brucei gambiense and are similar to those found in patients

Genetic analysis of phenotype in Trypanosoma brucei: a classical approach to potentially complex traits

Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map

Genetic exchange in Trypanosoma brucei: evidence for mating prior to metacyclic stage development.

Genome and phylogenetic analyses of trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty

Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors

High Levels of Genetic Diversity within Nilo-Saharan Populations: Implications for Human Adaptation

Human African trypanosomiasis presenting at least 29 years after infection--what can this teach us about the pathogenesis and control of this neglected tropical disease?

Human and animal Trypanosomes in Côte d'Ivoire form a single breeding population

Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis

Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population

Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factor

Multilocus genotyping of Cryptosporidium parvum Type 2: population genetics and sub-structuring

No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

Novel African trypanocidal agents: membrane rigidifying peptides

Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection

Persistently High Incidences of Trypanosoma brucei rhodesiense Sleeping Sickness With Contrasting Focus-Dependent Clinical Phenotypes in Malawi

Population Genetics and Reproductive Strategies of African Trypanosomes: Revisiting Available Published Data

Population genetic structure of Guinea Trypanosoma brucei gambiense isolates according to host factors

Population genetics of Trypanosoma brucei gambiense in sleeping sickness patients with treatment failures in the focus of Mbuji-Mayi, Democratic Republic of the Congo

Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci

Population genomics reveals the origin and asexual evolution of human infective trypanosomes

Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum

Research capacity. Enabling the genomic revolution in Africa

Resolving the apparent transmission paradox of African sleeping sickness

Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection

Role of expression site switching in the development of resistance to human Trypanosome Lytic Factor-1 in Trypanosoma brucei brucei

SNPs in IL4 and IFNG show no protective associations with human African trypanosomiasis in the Democratic Republic of the Congo: a case-control study

Spatially and genetically distinct African Trypanosome virulence variants defined by host interferon-gamma response

T cell activation and the HLA locus associate with latent infections of human African trypanosomiasis

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

The genetic map and comparative analysis with the physical map of Trypanosoma brucei

The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis

The plasma membrane of bloodstream-form African trypanosomes confers susceptibility and specificity to killing by hydrophobic peptides

The population structure of the Cryptosporidium parvum population in Scotland: a complex picture

The sequence and analysis of Trypanosoma brucei chromosome II.

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation

Trypanosoma vivax displays a clonal population structure

Trypanosome genetics: populations, phenotypes and diversity

Trypanosome resistance to human innate immunity: targeting Achilles’ heel ⬇️

Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters.

Whole-genome sequencing of Trypanosoma brucei reveals introgression between subspecies that is associated with virulence