Lista de obras - Cristina Bolzati - Dominio Público Uruguay

'3+1' mixed-ligand oxotechnetium(V) complexes with affinity for melanoma: synthesis and evaluation in vitro and in vivo

artículo científico publicado en 2000

(99m)Tc(N)-DBODC(5), a potential radiolabeled probe for SPECT of multidrug resistance: in vitro study.

artículo científico publicado en 2013

(99m)Tc-radiolabelled peptides for tumour imaging: present and future.

artículo científico publicado en 2010

An 86Y-labeled mirror-image oligonucleotide: influence of Y-DOTA isomers on the biodistribution in rats

artículo científico publicado en 2008

An alternative approach to the preparation of (188)Re radiopharmaceuticals from generator-produced [(188)ReO(4)](-): efficient synthesis of (188)Re(V)-meso-2,3-dimercaptosuccinic acid

scientific article published on 01 April 2000

Assessment of the best N(3-) donors in preparation of [M(N)(PNP)]-based (M=(99m)Tc-; (188)Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methy

artículo científico publicado en 2014

Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors

artículo científico publicado en 2003

Avidin-biotin system: a small library of cysteine biotinylated derivatives designed for the [99mTc(N)(PNP)]2+ metal fragment.

artículo científico publicado en 2007

Biological in vitro and in vivo studies of a series of new asymmetrical cationic [99mTc(N)(DTC-Ln)(PNP)]+ complex (DTC-Ln = alicyclic dithiocarbamate and PNP = diphosphinoamine).

artículo científico publicado en 2010

Characterisation via electrospray ionisation multistage mass spectrometry of three related series of nitrido technetium complexes containing phosphinothiolate and dithiocarbamate ligands

artículo científico publicado en 2005

Chelating systems for (99m)Tc/(188)Re in the development of radiolabeled peptide pharmaceuticals

artículo científico

Chemistry of the strong electrophilic metal fragment [(99)Tc(N)(PXP)](2+) (PXP = diphosphine ligand). A novel tool for the selective labeling of small molecules.

artículo científico publicado en 2002

Contribution of electrospray mass spectrometry for the characterization, design, and development of nitrido technetium and rhenium heterocomplexes as potential radiopharmaceuticals.

artículo científico publicado en 2004

Development of 177Lu-scFvD2B as a Potential Immunotheranostic Agent for Tumors Overexpressing the Prostate Specific Membrane Antigen

artículo científico publicado en 2020

Electrospray ionization mass spectrometry in the structural characterization of a mixed nitrido-Tc heterocomplex of interest for myocardial imaging

artículo científico publicado en 2003

Electrospray mass spectrometry of a series of mixed nitrido 99gTc- heterocomplexes conjugated with bioactive molecules.

artículo científico publicado en 2004

Enzymatic Methods for the Site-Specific Radiolabeling of Targeting Proteins

artículo científico publicado en 2021

Folic acid-conjugated europium complexes as luminescent probes for selective targeting of cancer cells

artículo científico publicado en 2015

From symmetrical to asymmetrical nitrido phosphino-thiol complexes: a new class of neutral mixed-ligand (99m)Tc compounds as potential brain imaging agents

artículo científico publicado en 2006

High-yield synthesis of the terminal 188Re triple bond N multiple bond from generator-produced [188ReO4](-).

artículo científico publicado en 2003

Improved synthesis on solid phase of dithiocarbamic cRGD-derivative and 99m Tc-radiolabelling

scientific article published on 01 February 2019

Insights into the failure of the potential, neutral myocardial imaging agent TcN-NOET: physicochemical identification of by-products and degradation species

artículo científico publicado en 2011

Labeling and biodistribution studies of Tc-99m radiopharmaceuticals with (o-hydroxyphenyl)diphenylphosphine

scientific article published on 01 January 1998

Labeling of fatty acid ligands with the strong electrophilic metal fragment [99mTc(N)(PNP)]2+ (PNP=diphosphane ligand)

artículo científico publicado en 2008

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties.

artículo científico publicado en 2016

New approach to the chemistry of technetium(V) and rhenium(V) phenylimido complexes: novel [M(NPh)PNP]3+ metal fragments (M = Tc, Re; PNP = aminodiphosphine) suitable for the synthesis of stable mixed-ligand compounds

artículo científico publicado en 2005

Novel [99mTcIII(PS)2(Ln)] mixed-ligand compounds (PS = phosphino-thiolate; L = dithiocarbamate) useful in design and development of TcIII-based agents: synthesis, in vitro, and ex vivo biodistribution studies

scientific article published on 03 November 2014

Radiation effective dose assessment of [51Mn]- and [52Mn]-chloride

artículo científico publicado en 2019

Radiochemical and radiopharmacological characterization of a 64 Cu-labeled α-MSH analog conjugated with different chelators

artículo científico publicado en 2019

Radiopharmacological characterization of ⁶⁴Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma

artículo científico publicado en 2015

Reactivity of the [M(PS)2](+) building block (M = Re(III) and (99m)Tc(III); PS = phosphinothiolate) toward isopropylxanthate and pyridine-2-thiolate

artículo científico publicado en 2015

Subcellular distribution and metabolism studies of the potential myocardial imaging agent [99mTc(N)(DBODC)(PNP5)]+.

artículo científico publicado en 2008

Synthesis and Characterization of Nitrido Tc(V) and Re(V) Complexes with Ferrocenedithiocarboxylate {FcCS(2) = [Fe(C(5)H(4)CS(2))(C(5)H(5))](-)}

artículo científico publicado en 1997

Synthesis and biologic evaluation of monocationic asymmetric 99mTc-nitride heterocomplexes showing high heart uptake and improved imaging properties.

artículo científico publicado en 2003

Synthesis and biological evaluation of new [Tc(N)(PS)]-based mixed-ligand compounds useful in the design of target-specific radiopharmaceuticals: the 2-methoxyphenylpiperazine dithiocarbamate derivatives as an example.

artículo científico publicado en 2010

Synthesis and characterization of rhenium(iii) complexes with (Ph2PCH2CH2)2NR diphosphinoamine ligands

artículo científico publicado en 2017

Synthesis of a Novel Class of Trigonal Bipyramidal Nitrido Tc(V) Complexes with Phosphino-Thiol Ligands. Crystal Structure of [(99g)Tc(N)(L(1))(2)] [L(1) = 2-(Diphenylphosphino)ethanethiolato] and [(99g)Tc(N)(L(5))(2)] [L(5) = 2-(Ditolylphosphino)pr

artículo científico publicado en 1999

Synthesis of a novel class of nitrido Tc-99m radiopharmaceuticals with phosphino-thiol ligands showing transient heart uptake

artículo científico publicado en 2000

Synthesis of hybrid distamycin–cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents

artículo científico publicado en 2000

Synthesis, Characterization, and Initial Biological Evaluation of [99m Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging

artículo científico publicado en 2018

Synthesis, characterization and biological evaluation of [188Re(N)(cys ∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals.

artículo científico publicado en 2010

Synthesis, characterization, and biological evaluation of neutral nitrido technetium(V) mixed ligand complexes containing dithiolates and aminodiphosphines. A novel system for linking technetium to biomolecules

artículo científico publicado en 2004

Technetium and rhenium in five-coordinate symmetrical and dissymmetrical nitrido complexes with alkyl phosphino-thiol ligands. Synthesis and structural characterization.

artículo científico publicado en 2008

The [(99m)Tc(N)(PNP)](2+) metal fragment: a technetium-nitrido synthon for use with biologically active molecules. The N-(2-methoxyphenyl)piperazyl-cysteine analogues as examples.

artículo científico publicado en 2003

The [Tc(N)(PNP)]2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: in vitro and in vivo studies

artículo científico publicado en 2007

The crucial role of the diphosphine heteroatom X in the stereochemistry and stabilization of the substitution-inert [M(N)(PXP)]2+ metal fragments (M = Tc, Re; PXP = diphosphine ligand)

scientific article published on 01 December 2004

The emerging value of copper-64 for molecular imaging and therapy

scientific article published on 07 October 2020

Transglutaminase-mediated conjugation and nitride-technetium-99m labelling of a bis(thiosemicarbazone) bifunctional chelator

artículo científico publicado en 2018

Water-Soluble [Tc(N)(PNP)] Moiety for Room-Temperature <sup>99m</sup>Tc Labeling of Sensitive Target Vectors

artículo científico publicado en 2022

[99mTc][Tc(N)(DASD)(PNP n)]+ (DASD = 1,4-Dioxa-8-azaspiro[4,5]decandithiocarbamate, PNP n = Bisphosphinoamine) for Myocardial Imaging: Synthesis, Pharmacological and Pharmacokinetic Studies

scientific article published on 14 December 2018

[99mTc][Tc(N)PNP43]-labeled RGD peptides as new probes for a selective detection of αvβ3 Integrin: synthesis, structure-activity and pharmacokinetic studies

scientific article published on 17 October 2018

[99mTc]oxotechnetium(V) complexes amine-amide-dithiol chelates with dialkylaminoalkyl substituents as potential diagnostic probes for malignant melanoma

scientific article published on 01 September 2001

Lista de obras de Cristina Bolzati

'3+1' mixed-ligand oxotechnetium(V) complexes with affinity for melanoma: synthesis and evaluation in vitro and in vivo

(99m)Tc(N)-DBODC(5), a potential radiolabeled probe for SPECT of multidrug resistance: in vitro study.

(99m)Tc-radiolabelled peptides for tumour imaging: present and future.

An 86Y-labeled mirror-image oligonucleotide: influence of Y-DOTA isomers on the biodistribution in rats

An alternative approach to the preparation of (188)Re radiopharmaceuticals from generator-produced [(188)ReO(4)](-): efficient synthesis of (188)Re(V)-meso-2,3-dimercaptosuccinic acid

Assessment of the best N(3-) donors in preparation of [M(N)(PNP)]-based (M=(99m)Tc-; (188)Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methy

Asymmetrical nitrido tc-99m heterocomplexes as potential imaging agents for benzodiazepine receptors

Avidin-biotin system: a small library of cysteine biotinylated derivatives designed for the [99mTc(N)(PNP)]2+ metal fragment.

Biological in vitro and in vivo studies of a series of new asymmetrical cationic [99mTc(N)(DTC-Ln)(PNP)]+ complex (DTC-Ln = alicyclic dithiocarbamate and PNP = diphosphinoamine).

Characterisation via electrospray ionisation multistage mass spectrometry of three related series of nitrido technetium complexes containing phosphinothiolate and dithiocarbamate ligands

Chelating systems for (99m)Tc/(188)Re in the development of radiolabeled peptide pharmaceuticals

Chemistry of the strong electrophilic metal fragment [(99)Tc(N)(PXP)](2+) (PXP = diphosphine ligand). A novel tool for the selective labeling of small molecules.

Contribution of electrospray mass spectrometry for the characterization, design, and development of nitrido technetium and rhenium heterocomplexes as potential radiopharmaceuticals.

Development of 177Lu-scFvD2B as a Potential Immunotheranostic Agent for Tumors Overexpressing the Prostate Specific Membrane Antigen

Electrospray ionization mass spectrometry in the structural characterization of a mixed nitrido-Tc heterocomplex of interest for myocardial imaging

Electrospray mass spectrometry of a series of mixed nitrido 99gTc- heterocomplexes conjugated with bioactive molecules.

Enzymatic Methods for the Site-Specific Radiolabeling of Targeting Proteins

Folic acid-conjugated europium complexes as luminescent probes for selective targeting of cancer cells

From symmetrical to asymmetrical nitrido phosphino-thiol complexes: a new class of neutral mixed-ligand (99m)Tc compounds as potential brain imaging agents

High-yield synthesis of the terminal 188Re triple bond N multiple bond from generator-produced [188ReO4](-).

Improved synthesis on solid phase of dithiocarbamic cRGD-derivative and 99m Tc-radiolabelling

Insights into the failure of the potential, neutral myocardial imaging agent TcN-NOET: physicochemical identification of by-products and degradation species

Labeling and biodistribution studies of Tc-99m radiopharmaceuticals with (o-hydroxyphenyl)diphenylphosphine

Labeling of fatty acid ligands with the strong electrophilic metal fragment [99mTc(N)(PNP)]2+ (PNP=diphosphane ligand)

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties.

New approach to the chemistry of technetium(V) and rhenium(V) phenylimido complexes: novel [M(NPh)PNP]3+ metal fragments (M = Tc, Re; PNP = aminodiphosphine) suitable for the synthesis of stable mixed-ligand compounds

Novel [99mTcIII(PS)2(Ln)] mixed-ligand compounds (PS = phosphino-thiolate; L = dithiocarbamate) useful in design and development of TcIII-based agents: synthesis, in vitro, and ex vivo biodistribution studies

Radiation effective dose assessment of [51Mn]- and [52Mn]-chloride

Radiochemical and radiopharmacological characterization of a 64 Cu-labeled α-MSH analog conjugated with different chelators

Radiopharmacological characterization of ⁶⁴Cu-labeled α-MSH analogs for potential use in imaging of malignant melanoma

Reactivity of the [M(PS)2](+) building block (M = Re(III) and (99m)Tc(III); PS = phosphinothiolate) toward isopropylxanthate and pyridine-2-thiolate

Subcellular distribution and metabolism studies of the potential myocardial imaging agent [99mTc(N)(DBODC)(PNP5)]+.

Synthesis and Characterization of Nitrido Tc(V) and Re(V) Complexes with Ferrocenedithiocarboxylate {FcCS(2) = [Fe(C(5)H(4)CS(2))(C(5)H(5))](-)}

Synthesis and biologic evaluation of monocationic asymmetric 99mTc-nitride heterocomplexes showing high heart uptake and improved imaging properties.

Synthesis and biological evaluation of new [Tc(N)(PS)]-based mixed-ligand compounds useful in the design of target-specific radiopharmaceuticals: the 2-methoxyphenylpiperazine dithiocarbamate derivatives as an example.

Synthesis and characterization of rhenium(iii) complexes with (Ph2PCH2CH2)2NR diphosphinoamine ligands

Synthesis of a Novel Class of Trigonal Bipyramidal Nitrido Tc(V) Complexes with Phosphino-Thiol Ligands. Crystal Structure of [(99g)Tc(N)(L(1))(2)] [L(1) = 2-(Diphenylphosphino)ethanethiolato] and [(99g)Tc(N)(L(5))(2)] [L(5) = 2-(Ditolylphosphino)pr

Synthesis of a novel class of nitrido Tc-99m radiopharmaceuticals with phosphino-thiol ligands showing transient heart uptake

Synthesis of hybrid distamycin–cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents

Synthesis, Characterization, and Initial Biological Evaluation of [99m Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging

Synthesis, characterization and biological evaluation of [188Re(N)(cys ∼)(PNP)]+/0 mixed-ligand complexes as prototypes for the development of 188Re(N)-based target-specific radiopharmaceuticals.

Synthesis, characterization, and biological evaluation of neutral nitrido technetium(V) mixed ligand complexes containing dithiolates and aminodiphosphines. A novel system for linking technetium to biomolecules

Technetium and rhenium in five-coordinate symmetrical and dissymmetrical nitrido complexes with alkyl phosphino-thiol ligands. Synthesis and structural characterization.

The [(99m)Tc(N)(PNP)](2+) metal fragment: a technetium-nitrido synthon for use with biologically active molecules. The N-(2-methoxyphenyl)piperazyl-cysteine analogues as examples.

The [Tc(N)(PNP)]2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: in vitro and in vivo studies

The crucial role of the diphosphine heteroatom X in the stereochemistry and stabilization of the substitution-inert [M(N)(PXP)]2+ metal fragments (M = Tc, Re; PXP = diphosphine ligand)

The emerging value of copper-64 for molecular imaging and therapy

Transglutaminase-mediated conjugation and nitride-technetium-99m labelling of a bis(thiosemicarbazone) bifunctional chelator

Water-Soluble [Tc(N)(PNP)] Moiety for Room-Temperature <sup>99m</sup>Tc Labeling of Sensitive Target Vectors

[99mTc][Tc(N)(DASD)(PNP n)]+ (DASD = 1,4-Dioxa-8-azaspiro[4,5]decandithiocarbamate, PNP n = Bisphosphinoamine) for Myocardial Imaging: Synthesis, Pharmacological and Pharmacokinetic Studies

[99mTc][Tc(N)PNP43]-labeled RGD peptides as new probes for a selective detection of αvβ3 Integrin: synthesis, structure-activity and pharmacokinetic studies

[99mTc]oxotechnetium(V) complexes amine-amide-dithiol chelates with dialkylaminoalkyl substituents as potential diagnostic probes for malignant melanoma