Lista de obras - Giuseppina Andreotti - Dominio Público Uruguay

A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin.

artículo científico publicado en 2005

A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG. ⬇️

artículo científico publicado en 2017

A thermodynamic assay to test pharmacological chaperones for Fabry disease.

artículo científico publicado en 2013

An extremely thermostable aromatic aminotransferase from the hyperthermophilic archaeon Pyrococcus furiosus.

artículo científico publicado en 1995

CDG Therapies: From Bench to Bedside.

artículo científico publicado en 2018

Challenging popular tools for the annotation of genetic variations with a real case, pathogenic mutations of lysosomal alpha-galactosidase

artículo científico publicado en 2018

Characterization of aromatic aminotransferases from the hyperthermophilic archaeon Thermococcus litoralis.

artículo científico publicado en 1994

Conformational response to ligand binding in phosphomannomutase2: insights into inborn glycosylation disorder.

artículo científico publicado en 2014

Converting the Highly Amyloidogenic Human Calcitonin into a Powerful Fibril Inhibitor by Three-dimensional Structure Homology with a Non-amyloidogenic Analogue ⬇️

artículo científico publicado el 15 de noviembre de 2010

D2A sequence of the urokinase receptor induces cell growth through αvβ3 integrin and EGFR.

artículo científico publicado en 2017

Direct enzymatic glucosylation of naringin in grapefruit juice by alpha-D-glucosidase from the marine mollusc Aplysia fasciata.

artículo científico publicado en 2008

Drug Repositioning for Fabry Disease: Acetylsalicylic Acid Potentiates the Stabilization of Lysosomal Alpha-Galactosidase by Pharmacological Chaperones

artículo científico publicado en 2022

Drug Repurposing and Lysosomal Storage Disorders: A Trick to Treat

artículo científico publicado en 2024

Drug repositioning can accelerate discovery of pharmacological chaperones

artículo científico publicado en 2015

E-Learning for Rare Diseases: An Example Using Fabry Disease

artículo científico publicado en 2017

Enzymatic syntheses and selective hydrolysis of O-beta-D-galactopyranosides using a marine mollusc beta-galactosidase

artículo científico publicado en 2005

Fabry_CEP: a tool to identify Fabry mutations responsive to pharmacological chaperones.

artículo científico publicado en 2013

Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2

artículo científico publicado en 2015

High-Yielding Enzymatic α-Glucosylation of Pyridoxine by Marine α-Glucosidase from Aplysia fasciata

artículo científico publicado en 2006

Hydrolyses and transglycosylations performed by purified alpha-D-glucosidase of the marine mollusc Aplysia fasciata

artículo científico publicado en 2005

Hydrosoluble antioxidants by enzymatic glucosylation of a vitamin E derivative using marine α-D-glucosidase from Aplysia fasciata

artículo científico publicado en 2011

Identification and analysis of conserved pockets on protein surfaces

artículo científico publicado en 2013

Identification of Trombospondin-1 as a Novel Amelogenin Interactor by Functional Proteomics

artículo científico publicado en 2017

Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease

artículo científico publicado en 2016

Indole-3-glycerol-phosphate synthase from Sulfolobus solfataricus as a model for studying thermostable TIM-barrel enzymes.

artículo científico publicado en 1994

Looking for protein stabilizing drugs with thermal shift assay.

artículo científico publicado en 2015

Marine glycosyl hydrolases in the hydrolysis and synthesis of oligosaccharides.

artículo científico publicado en 2006

Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.

artículo científico publicado en 2003

Pharmacological Chaperones: A Therapeutic Approach for Diseases Caused by Destabilizing Missense Mutations

scientific article published on 13 January 2020

Prediction of the responsiveness to pharmacological chaperones: lysosomal human alpha-galactosidase, a case of study

artículo científico publicado en 2010

Purification and characterization of a beta-D-mannosidase from the marine anaspidean Aplysia fasciata

artículo científico publicado en 2005

Rational Design, Synthesis, Characterization and Evaluation of Iodinated 4,4'-Bipyridines as New Transthyretin Fibrillogenesis Inhibitors

artículo científico publicado en 2020

Taming molecular flexibility to tackle rare diseases.

artículo científico publicado en 2015

The Analysis of Variants in the General Population Reveals That Is Extremely Tolerant to Missense Mutations and That Diagnosis of PMM2-CDG Can Benefit from the Identification of Modifiers

artículo científico publicado en 2018

The Large Phenotypic Spectrum of Fabry Disease Requires Graduated Diagnosis and Personalized Therapy: A Meta-Analysis Can Help to Differentiate Missense Mutations

artículo científico publicado en 2016

The active site of Sulfolobus solfataricus aspartate aminotransferase.

artículo científico publicado en 1991

Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy

artículo científico publicado en 2003

β-Glucose-1,6-Bisphosphate Stabilizes Pathological Phophomannomutase2 Mutants In Vitro and Represents a Lead Compound to Develop Pharmacological Chaperones for the Most Common Disorder of Glycosylation, PMM2-CDG ⬇️

artículo científico publicado en 2019

Lista de obras de Giuseppina Andreotti

A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin.

A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG. ⬇️

A thermodynamic assay to test pharmacological chaperones for Fabry disease.

An extremely thermostable aromatic aminotransferase from the hyperthermophilic archaeon Pyrococcus furiosus.

CDG Therapies: From Bench to Bedside.

Challenging popular tools for the annotation of genetic variations with a real case, pathogenic mutations of lysosomal alpha-galactosidase

Characterization of aromatic aminotransferases from the hyperthermophilic archaeon Thermococcus litoralis.

Conformational response to ligand binding in phosphomannomutase2: insights into inborn glycosylation disorder.

Converting the Highly Amyloidogenic Human Calcitonin into a Powerful Fibril Inhibitor by Three-dimensional Structure Homology with a Non-amyloidogenic Analogue ⬇️

D2A sequence of the urokinase receptor induces cell growth through αvβ3 integrin and EGFR.

Direct enzymatic glucosylation of naringin in grapefruit juice by alpha-D-glucosidase from the marine mollusc Aplysia fasciata.

Drug Repositioning for Fabry Disease: Acetylsalicylic Acid Potentiates the Stabilization of Lysosomal Alpha-Galactosidase by Pharmacological Chaperones

Drug Repurposing and Lysosomal Storage Disorders: A Trick to Treat

Drug repositioning can accelerate discovery of pharmacological chaperones

E-Learning for Rare Diseases: An Example Using Fabry Disease

Enzymatic syntheses and selective hydrolysis of O-beta-D-galactopyranosides using a marine mollusc beta-galactosidase

Fabry_CEP: a tool to identify Fabry mutations responsive to pharmacological chaperones.

Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2

High-Yielding Enzymatic α-Glucosylation of Pyridoxine by Marine α-Glucosidase from Aplysia fasciata

Hydrolyses and transglycosylations performed by purified alpha-D-glucosidase of the marine mollusc Aplysia fasciata

Hydrosoluble antioxidants by enzymatic glucosylation of a vitamin E derivative using marine α-D-glucosidase from Aplysia fasciata

Identification and analysis of conserved pockets on protein surfaces

Identification of Trombospondin-1 as a Novel Amelogenin Interactor by Functional Proteomics

Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease

Indole-3-glycerol-phosphate synthase from Sulfolobus solfataricus as a model for studying thermostable TIM-barrel enzymes.

Looking for protein stabilizing drugs with thermal shift assay.

Marine glycosyl hydrolases in the hydrolysis and synthesis of oligosaccharides.

Modulating calcitonin fibrillogenesis: an antiparallel alpha-helical dimer inhibits fibrillation of salmon calcitonin.

Pharmacological Chaperones: A Therapeutic Approach for Diseases Caused by Destabilizing Missense Mutations

Prediction of the responsiveness to pharmacological chaperones: lysosomal human alpha-galactosidase, a case of study

Purification and characterization of a beta-D-mannosidase from the marine anaspidean Aplysia fasciata

Rational Design, Synthesis, Characterization and Evaluation of Iodinated 4,4'-Bipyridines as New Transthyretin Fibrillogenesis Inhibitors

Taming molecular flexibility to tackle rare diseases.

The Analysis of Variants in the General Population Reveals That Is Extremely Tolerant to Missense Mutations and That Diagnosis of PMM2-CDG Can Benefit from the Identification of Modifiers

The Large Phenotypic Spectrum of Fabry Disease Requires Graduated Diagnosis and Personalized Therapy: A Meta-Analysis Can Help to Differentiate Missense Mutations

The active site of Sulfolobus solfataricus aspartate aminotransferase.

Two distinct calcium-calmodulin interactions with N-terminal regions of the olfactory and rod cyclic nucleotide-gated channels characterized by NMR spectroscopy

β-Glucose-1,6-Bisphosphate Stabilizes Pathological Phophomannomutase2 Mutants In Vitro and Represents a Lead Compound to Develop Pharmacological Chaperones for the Most Common Disorder of Glycosylation, PMM2-CDG ⬇️