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Lista de obras de Lee Jia

A Biofunctional Molecular Beacon for Detecting Single Base Mutations in Cancer Cells

artículo científico publicado en 2016

A Flavonoid Glycoside Compound from Murraya paniculata (L.) Interrupts Metastatic Characteristics of A549 Cells by Regulating STAT3/NF-κB/COX-2 and EGFR Signaling Pathways

artículo científico publicado en 2017

A functionalized dumbbell probe-based cascading exponential amplification DNA machine enables amplified probing of microRNAs

scientific article published on 01 February 2020

A novel S-nitrosocaptopril monohydrate for pulmonary arterial hypertension: H2O and -SNO intermolecular stabilization chemistry

artículo científico publicado en 2018

A novel SPE-HPLC method for simultaneous determination of selected sulfonated phthalocyanine zinc complexes in mouse plasma following cassette dosing

artículo científico publicado en 2013

A novel UPLC-MS/MS method for sensitive quantitation of boldine in plasma, a potential anti-inflammatory agent: application to a pharmacokinetic study in rats

artículo científico publicado en 2014

A novel UPLC/MS/MS method for rapid determination of metapristone in rat plasma, a new cancer metastasis chemopreventive agent derived from mifepristone (RU486).

artículo científico publicado en 2014

A novel UPLC/MS/MS method for rapid determination of murrayone in rat plasma and its pharmacokinetics

scientific article published on 16 December 2019

A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment

artículo científico publicado en 2016

A novel nanomissile targeting two biomarkers and accurately bombing CTCs with doxorubicin.

artículo científico publicado en 2017

A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis.

artículo científico publicado en 2015

A smart pH-responsive nano-carrier as a drug delivery system for the targeted delivery of ursolic acid: suppresses cancer growth and metastasis by modulating P53/MMP-9/PTEN/CD44 mediated multiple signaling pathways.

artículo científico publicado en 2017

AIDS treatment with novel anti-HIV compounds improved by nanotechnology

artículo científico publicado en 2010

Abortifacient metapristone (RU486 derivative) interrupts CXCL12/CXCR4 axis for ovarian metastatic chemoprevention.

artículo científico publicado en 2017

Achyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT

scientific article published on 31 August 2020

Antiangiogenic effects of S-nitrosocaptopril crystals as a nitric oxide donor

artículo científico publicado en 2000

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

artículo científico publicado en 2006

Aptamer-Conjugated Chitosan-Anchored Liposomal Complexes for Targeted Delivery of Erlotinib to EGFR-Mutated Lung Cancer Cells.

artículo científico publicado en 2017

Aspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil

artículo científico publicado en 2015

Author Correction: Achyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT

scientific article published on 13 October 2020

Autonomous assembly of ordered metastable DNA nanoarchitecture and in situ visualizing of intracellular microRNAs.

artículo científico publicado en 2016

Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048).

artículo científico publicado en 2008

Bioactivity-guided fast screen and identification of cancer metastasis chemopreventive components from raw extracts of Murraya exotica.

artículo científico publicado en 2015

Biomedical activities of endohedral metallofullerene optimized for nanopharmaceutics.

artículo científico publicado en 2010

Biostability and pharmacokinetics of LJP 920, an octameric Gal (alpha1-3) Gal conjugate for the inhibition of xenotransplantation rejection.

artículo científico publicado en 2001

Blood Flow Regulation by S-Nitrosohemoglobin in the Physiological Oxygen Gradient

scientific article published in Science

CXCR7 is not obligatory for CXCL12-CXCR4-induced epithelial-mesenchymal transition in human ovarian cancer

scientific article published on 16 October 2018

Carbendazim: disposition, cellular permeability, metabolite identification, and pharmacokinetic comparison with its nanoparticle.

artículo científico publicado en 2003

Cascade DNA nanomachine and exponential amplification biosensing.

artículo científico publicado en 2015

China and the United States--Global partners, competitors and collaborators in nanotechnology development.

artículo científico publicado en 2015

Co-delivery of oxygen and erlotinib by aptamer-modified liposomal complexes to reverse hypoxia-induced drug resistance in lung cancer.

artículo científico publicado en 2017

Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib.

artículo científico publicado en 2019

Collapse of chain anadiplosis-structured DNA nanowires for highly sensitive colorimetric assay of nucleic acids.

artículo científico publicado en 2017

Comparisons between Graphene Oxide and Graphdiyne Oxide in Physicochemistry Biology and Cytotoxicity

artículo científico publicado en 2018

Correction: A novel nanomissile targeting two biomarkers and accurately bombing CTCs with doxorubicin

artículo científico publicado en 2018

Corrigendum to 'Metapristone suppresses non-small cell lung cancer proliferation and metastasis via modulating RAS/RAF/MEK/MAPK signaling pathway' [Biomed. Pharmacother. 90 (2017) 437-445].

artículo científico publicado en 2018

Corrigendum to ‘Intracellular distribution and mechanisms of actions of photosensitizer Zinc(II)-phthalocyanine solubilized in Cremophor EL against human hepatocellular carcinoma HepG2 cells’ [Cancer letters, 2013, 330(1): 49–56]

artículo científico publicado en 2018

Current evaluation of the millennium phytomedicine- ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine.

artículo científico publicado en 2009

Current evaluation of the millennium phytomedicine--ginseng (I): etymology, pharmacognosy, phytochemistry, market and regulations

scientific article published on January 2009

Dendrimeric anticancer prodrugs for targeted delivery of ursolic acid to folate receptor-expressing cancer cells: synthesis and biological evaluation.

artículo científico publicado en 2015

Double-stem Hairpin Probe and Ultrasensitive Colorimetric Detection of Cancer-related Nucleic Acids

artículo científico publicado en 2016

Drug enterohepatic circulation and disposition: constituents of systems pharmacokinetics.

artículo científico

Dual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells

artículo científico publicado en 2019

Dual-cyclical nucleic acid strand-displacement polymerization based signal amplification system for highly sensitive determination of p53 gene.

artículo científico publicado en 2016

Effect of nanonization on absorption of 301029: ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry

artículo científico publicado en 2002

Effect of nitric oxide on cytotoxicity of Taxol: enhanced Taxol transcellular permeability.

artículo científico publicado en 2003

Effects of cyclosporine A and itraconazole on permeability, biliary excretion and pharmacokinetics of amlodipine.

artículo científico publicado en 2008

EpCAM aptamer-functionalized mesoporous silica nanoparticles for efficient colon cancer cell-targeted drug delivery

artículo científico

Epigenetic modulation of human breast cancer by metallofullerenol nanoparticles: in vivo treatment and in vitro analysis

artículo científico publicado en 2011

Erlotinib-guided self-assembled trifunctional click nanotheranostics for distinguishing druggable mutations and synergistic therapy of NSCLC

artículo científico publicado en 2018

Ex vivo and in vivo capture and deactivation of circulating tumor cells by dual-antibody-coated nanomaterials

artículo científico publicado en 2015

Exploring cancer metastasis prevention strategy: interrupting adhesion of cancer cells to vascular endothelia of potential metastatic tissues by antibody-coated nanomaterial

artículo científico publicado en 2015

Fibronectin 1 promotes melanoma proliferation and metastasis by inhibiting apoptosis and regulating EMT

artículo científico publicado en 2019

Fluorescent Se-modified carbon nitride nanosheets as biomimetic catalases for free-radical scavenging

scientific article published on 18 December 2019

Functionalized MoS2-erlotinib produces hyperthermia under NIR.

artículo científico publicado en 2019

Global deregulation of ginseng products may be a safety hazard to warfarin takers: solid evidence of ginseng-warfarin interaction

artículo científico publicado en 2017

HAMPT, A Novel Quadruple Drug Combination Designed for Cancer Metastatic Chemoprevention: From Hypothesis to Proof-of-concept

artículo científico publicado en 2019

Immunomagnetic antibody plus aptamer pseudo-DNA nanocatenane followed by rolling circle amplication for highly-sensitive CTC detection

artículo científico publicado en 2018

Immunomodulatory effects of Pseudostellaria heterophylla peptide on spleen lymphocytes via a Ca2+/CaN/NFATc1/IFN-γ pathway

artículo científico publicado en 2019

Impacts of Nanoparticles on Cardiovascular Diseases: Modulating Metabolism and Function of Endothelial Cells ⬇️

artículo científico publicado el 1 de octubre de 2012

In vitro and in vivo efficacy and safety evaluation of metapristone and mifepristone as cancer metastatic chemopreventive agents.

artículo científico publicado en 2016

Increasingly branched rolling circle amplification for the cancer gene detection

artículo científico publicado en 2016

Intelligent DNA machine for the ultrasensitive colorimetric detection of nucleic acids.

artículo científico publicado en 2015

Interspecies pharmacokinetics and in vitro metabolism of SQ109.

artículo científico publicado en 2006

Intracellular distribution and mechanisms of actions of photosensitizer Zinc(II)-phthalocyanine solubilized in Cremophor EL against human hepatocellular carcinoma HepG2 cells.

artículo científico publicado en 2012

Isolation and characterization of living circulating tumor cells in patients by immunomagnetic negative enrichment coupled with flow cytometry

artículo científico publicado en 2015

JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo.

artículo científico publicado en 2010

LC–MS/MS assay and dog pharmacokinetics of the dimeric pyrrolobenzodiazepine SJG-136 (NSC 694501)

artículo científico publicado en 2006

Long-stem shaped multifunctional molecular beacon for highly sensitive nucleic acids determination via intramolecular and intermolecular interactions based strand displacement amplification.

artículo científico publicado en 2017

Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis.

artículo científico publicado en 2010

Metapristone (RU486 metabolite) suppresses NSCLC by targeting EGFR-mediated PI3K/AKT pathway.

artículo científico publicado en 2017

Metapristone suppresses non-small cell lung cancer proliferation and metastasis via modulating RAS/RAF/MEK/MAPK signaling pathway.

artículo científico publicado en 2017

Mifepristone inhibits ovarian cancer metastasis by intervening in SDF-1/CXCR4 chemokine axis

artículo científico publicado en 2017

Mitaplatin increases sensitivity of tumor cells to cisplatin by inducing mitochondrial dysfunction.

artículo científico publicado en 2012

Mitochondria and Nuclei Dual-Targeted Hollow Carbon Nanospheres for Cancer Chemophotodynamic Synergistic Therapy

scientific article published on 02 April 2019

Molybdenum disulfide-based hyaluronic acid-guided multifunctional theranostic nanoplatform for magnetic resonance imaging and synergetic chemo-photothermal therapy

artículo científico publicado en 2019

Mouse pharmacokinetics and metabolism of the curcumin analog, 4-piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993).

artículo científico publicado en 2014

Multivalent conjugation of antibody to dendrimers for the enhanced capture and regulation on colon cancer cells

artículo científico publicado en 2015

Nanoproteomics: a new sprout from emerging links between nanotechnology and proteomics.

artículo científico

Nanotechnology-based intelligent drug design for cancer metastasis treatment

artículo científico publicado en 2013

New molecular beacon for p53 gene point mutation and significant potential in serving as the polymerization primer.

artículo científico publicado en 2014

Nitric oxide inhibits hetero-adhesion of cancer cells to endothelial cells: restraining circulating tumor cells from initiating metastatic cascade.

artículo científico publicado en 2014

Novel multifunction-integrated molecular beacon for the amplification detection of DNA hybridization based on primer/template-free isothermal polymerization.

artículo científico publicado en 2015

Optimal structural design of mannosylated nanocarriers for macrophage targeting.

artículo científico publicado en 2014

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

artículo científico publicado en 2006

Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug

artículo científico publicado en 2005

Pharmacokinetic differences of mifepristone between sexes in animals.

artículo científico publicado en 2018

Pharmacokinetics and metabolism study of isoboldine, a major bioactive component from Radix Linderae in male rats by UPLC-MS/MS.

artículo científico publicado en 2015

Pharmacokinetics and pharmacodynamics of Phor21-betaCG(ala), a lytic peptide conjugate.

artículo científico publicado en 2008

Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats

artículo científico publicado en 2010

Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas ⬇️

artículo científico publicado el 27 de julio de 2011

Physicochemistry, pharmacokinetics, and pharmacodynamics of S‐nitrosocaptopril crystals, a new nitric oxide donor††Abbreviations: CapNO, S‐nitrosocaptopril; Cap, Captopril; RSNOs, S‐nitrosothiols; ACE, angiotensin converting enzyme; MAP, me

artículo científico publicado en 1999

Polynitrosylated proteins: characterization, bioactivity, and functional consequences.

artículo científico publicado en 1996

Potential serious interactions between nutraceutical ginseng and warfarin in patients with ischemic stroke

scientific article published on 29 December 2012

Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination ⬇️

artículo científico publicado el 18 de noviembre de 2010

Preclinical pharmacology of novel indolecarboxamide ML-970, an investigative anticancer agent

scientific article published on 25 February 2012

Programmable nanoassembly consisting of two hairpin-DNAs for p53 gene determination

artículo científico publicado en 2017

Promising Compounds From Murraya exotica for Cancer Metastasis Chemoprevention.

artículo científico publicado en 2016

Quantitative determination of apogossypol, a pro-apoptotic analog of gossypol, in mouse plasma using LC/MS/MS

artículo científico publicado en 2006

RCA-enhanced multifunctional molecule beacon-based strand-displacement amplification for sensitive microRNA detection

RU486 Metabolite Inhibits CCN1/Cyr61 Secretion by MDA-MB-231-Endothelial Adhesion

scientific article published on 20 November 2019

Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs

scientific article published on 14 November 2018

S-Nitrosocaptopril prevents cancer metastasis in vivo by creating the hostile bloodstream microenvironment against circulating tumor cells

artículo científico publicado en 2018

S-nitrosocaptopril interrupts adhesion of cancer cells to vascular endothelium by suppressing cell adhesion molecules via inhibition of the NF-кB and JAK/STAT signal pathways in endothelial cells.

artículo científico publicado en 2016

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

artículo científico publicado en 1996

Separation of ginseng active ingredients and their roles in cancer metastasis supplementary therapy

artículo científico publicado en 2013

Sex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite).

artículo científico publicado en 2017

Similarities and differences between embryonic implantation and CTC invasion: Exploring the roles of abortifacients in cancer metastasis chemoprevention

artículo científico publicado en 2022

Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release

article

Simultaneous determination of three Panax notoginseng saponins at sub-nanograms by LC-MS/MS in dog plasma for pharmacokinetics of compound Danshen tablets.

artículo científico publicado en 2010

Simultaneous estimation of pharmacokinetic properties in mice of three anti-tubercular ethambutol analogs obtained from combinatorial lead optimization.

artículo científico publicado en 2004

Specific hemosiderin deposition in spleen induced by a low dose of cisplatin: altered iron metabolism and its implication as an acute hemosiderin formation model

artículo científico publicado en 2010

Stepwise nanoassembly of a single hairpin probe and its biosensing

artículo científico publicado en 2018

Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis

artículo científico publicado en 2014

Synthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatment

artículo científico publicado en 2013

Synthesis, spectral characterization, and in vitro cellular activities of metapristone, a potential cancer metastatic chemopreventive agent derived from mifepristone (RU486).

artículo científico publicado en 2014

Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex.

artículo científico publicado en 2015

The Architecture and Function of Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles Loaded with Mifepristone: Repurposing Abortifacient for Cancer Metastatic Chemoprevention.

artículo científico publicado en 2016

The conduct of drug metabolism studies considered good practice (II): in vitro experiments

artículo científico publicado en 2007

The paradigm-shifting idea and its practice: from traditional abortion Chinese medicine Murraya paniculata to safe and effective cancer metastatic chemopreventives.

artículo científico publicado en 2016

The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology

artículo científico publicado en 2017

The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis.

artículo científico publicado en 2014

Therapeutic strategies underpinning the development of novel techniques for the treatment of HIV infection.

artículo científico publicado en 2010

Thirty-day rat toxicity study reveals reversible liver toxicity of mifepristone (RU486) and metapristone.

artículo científico publicado en 2016

Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.

scientific article published on 10 August 2007

Two-wheel drive-based DNA nanomachine and its sensing potential for highly sensitive analysis of cancer-related gene.

artículo científico publicado en 2016

UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma.

artículo científico publicado en 2014

Use of lung-specific exosomes for miRNA-126 delivery in non-small cell lung cancer

artículo científico publicado en 2020

WDR74 induces nuclear β-catenin accumulation and activates Wnt-responsive genes to promote lung cancer growth and metastasis

scientific article published on 12 December 2019

Warfarin and coumarin-like Murraya paniculata extract down-regulate EpCAM-mediated cell adhesion: individual components versus mixture for studying botanical metastatic chemopreventives

artículo científico publicado en 2016

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