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Lista de obras de Karim Malik

A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis

artículo científico publicado en 2007

A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

artículo científico publicado en 2020

A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway

artículo científico publicado en 2010

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

artículo científico publicado en 2013

Autoregulation of the human WT1 gene promoter

article

Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

artículo científico publicado en 2018

Characterization of 17.94, a novel anaplastic Wilms' tumor cell line

artículo científico publicado en 2012

Cloning and sequencing of the cDNA encoding a mouse tissue inhibitor of metalloproteinase-2.

artículo científico publicado en 1992

Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A.

artículo científico publicado en 2012

Epigenetic deregulation of GATA3 in neuroblastoma is associated with increased GATA3 protein expression and with poor outcomes

scientific article published on 12 December 2019

Epigenetic gene deregulation in cancer.

artículo científico publicado en 2000

Frequency and Timing of Loss of Imprinting at 11p13 and 11p15 in Wilms' Tumor Development

article

Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor

artículo científico publicado en 2009

Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma

artículo científico publicado en 2016

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours

artículo científico publicado en 2003

Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter

artículo científico publicado en 2015

Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors

artículo científico publicado en 2007

Identification of novel Wilms' tumor suppressor gene target genes implicated in kidney development

artículo científico publicado en 2007

Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells.

artículo científico publicado en 2006

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma

artículo científico publicado en 2015

Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.

artículo científico publicado en 2012

MYCN is recruited to the RASSF1A promoter but is not critical for DNA hypermethylation in neuroblastoma

artículo científico publicado el 31 de diciembre de 2012

PRMT1 promotes neuroblastoma cell survival through ATF5

artículo científico publicado en 2020

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells

artículo científico publicado en 2014

The molecular biology of Wilms' tumour

artículo científico publicado en 2001

The parathyroid hormone-responsive B1 gene is interrupted by a t(1;7)(q42;p15) breakpoint associated with Wilms' tumour

artículo científico publicado en 2003

The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines

artículo científico publicado en 2003

The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis

artículo científico publicado en 2017

Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma

artículo científico publicado en 2017

Transactivation of the WT1 antisense promoter is unique to the WT1[+/−] isoform

artículo científico publicado en 1999

Wilms' tumor: a paradigm for the new genetics.

artículo científico publicado en 2001

Wnt Signaling Is a Major Determinant of Neuroblastoma Cell Lineages

artículo científico publicado en 2019

Wnt Signalling Drives Context-Dependent Differentiation or Proliferation in Neuroblastoma

artículo científico publicado en 2018

Wnt signalling drives context-dependent differentiation or proliferation in neuroblastoma